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LAEIRIEALGAISAATAEFDGGLTVLTGETGAGKTMVVTGLHLLGGARADATKVRSGADRAVVEGRFTTA EVGDAVAAQVDGILDSSGAERDDDGSVIAARSVSRDGPSRAYLGGRSVPAKSLSGFTNELLTLHGQNDQL RLMRPDEQRAALDRYADVATQLHRYRTARDSWLEAKRDLDDRRRRAREMAQEADRLQFALNEIDVIDPHS GEDDALVAEIRRLSELDALREAVQTARAALSGESDDGFSAAHAVGQARSALEGTDDAPLKALAEQLGSAL TVLVDVSAELGGYLDELPTDTSSLETKLARQAELRTLTRKYAADVDGVLAWAGEARDRLAALDVSEETLA GLERRVEELQATVVAAAQDLTKVRVKAAKGLSKAVTAELSGLAMAGADFAISVTPLPARADDSAPLALPS GVTVHAGHDGVDAVEFGFAAHGGSDLLPLNKSASGGELSRVMLALEVVLSASTEGTTMVFDEVDAGVGGR AAVQIGRRLARLARTHQVIVVTHLPQVAAYADVHLVVEGVAGRDDGRKARAKSSGVRRLDDDDRVAELAR MLAGLGESDSGRAHARELLDAARAERAAAD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_3288 | - | - | 100% (591) | DNA repair protein RecN |
M. vanbaalenii PYR-1 | Mvan_2175 | - | 6e-12 | 22.39% (594) | chromosome segregation protein SMC |
M. vanbaalenii PYR-1 | Mvan_3339 | uvrA | 3e-05 | 25.89% (224) | excinuclease ABC subunit A |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1722 | recN | 0.0 | 71.86% (590) | DNA repair protein recN (recombination protein N) |
M. gilvum PYR-GCK | Mflv_3507 | - | 0.0 | 87.94% (597) | DNA repair protein RecN |
M. tuberculosis H37Rv | Rv1696 | recN | 0.0 | 71.86% (590) | DNA repair protein recN (recombination protein N) |
M. leprae Br4923 | MLBr_01360 | recN | 0.0 | 70.42% (595) | recombination and DNA repair |
M. abscessus ATCC 19977 | MAB_2361 | - | 0.0 | 69.70% (594) | DNA repair protein RecN |
M. marinum M | MMAR_2501 | recN | 0.0 | 72.16% (589) | DNA repair protein, RecN |
M. avium 104 | MAV_3075 | recN | 0.0 | 71.09% (595) | DNA repair protein RecN |
M. smegmatis MC2 155 | MSMEG_2423 | smc | 4e-08 | 22.30% (574) | chromosome segregation protein SMC |
M. thermoresistible (build 8) | TH_1548 | recN | 0.0 | 74.03% (593) | PROBABLE DNA REPAIR PROTEIN RECN (RECOMBINATION PROTEIN N) |
M. ulcerans Agy99 | MUL_1685 | recN | 0.0 | 72.33% (589) | DNA repair protein, RecN |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_3288|M.vanbaalenii_PYR-1 -MLAEIRIEALGAIS-AATAEFDGGLTVLTGETGAGKTMVVTGLHLLGGA Mflv_3507|M.gilvum_PYR-GCK -MLAEIRIEALGAIN-AATAEFDGGLTVLTGETGAGKTMVVTGLHLLGGA TH_1548|M.thermoresistible__bu -VLSEIRIESLGAIS-SATAEFDRGLTVLTGETGTGKTMVVTGLHLLGGG MLBr_01360|M.leprae_Br4923 -MLTEIRIESLGAIS-VATAEFDRGLTVLTGETGTGKTMVVTGLHLLGGA MAV_3075|M.avium_104 -MLTEIRIESLGAIS-AAVGEFDRGLTVLTGETGTGKTMVVTGLHLLGGA Mb1722|M.bovis_AF2122/97 -MLTELRIESLGAIS-VATAEFDRGFTVLTGETGTGKTMVVTGLHLLGGA Rv1696|M.tuberculosis_H37Rv -MLTELRIESLGAIS-VATAEFDRGFTVLTGETGTGKTMVVTGLHLLGGA MMAR_2501|M.marinum_M -MLTEIRIESLGAIS-AATAEFDRGLTVLTGETGTGKTMVVTGLHLLGGA MUL_1685|M.ulcerans_Agy99 -MLTEIRIESLGAIS-AATAEFDRGLTVLTGETGTGKTMVVTGLHLLGGA MAB_2361|M.abscessus_ATCC_1997 -MLTEIRIESLGAIP-AATAEFDSGLTVLTGETGAGKTMVVTSLHLLGGA MSMEG_2423|M.smegmatis_MC2_155 MHLKSLTLKGFKSFASPTTLRFEPGITCVVGPNGSGKSNVVDALTWVMGE * .: ::.: :: :. .*: *:* :.* .*:**: ** .* : * Mvan_3288|M.vanbaalenii_PYR-1 RADATKVRSGADRAVVEGRFTTAEVGDAVAAQVDGILDSSGAERDDDGSV Mflv_3507|M.gilvum_PYR-GCK RADATKVRSGSDRAVVEGRFTTTEVGDAVSARVDGILDSSGAERDDDGSV TH_1548|M.thermoresistible__bu RADPTRVRSGAQRAVVEGRFSTAELLDEAAARVDDILAASGAERDEDGTV MLBr_01360|M.leprae_Br4923 RADASRVRSGANRAVVEGRFTTTDLDDVVVAQLDGILNASGSERDEDGSV MAV_3075|M.avium_104 RADATRVRSGADRAIVEGRFTTTDLDEALVVRLDEMLDASGAERDEDGSV Mb1722|M.bovis_AF2122/97 RADATRVRSGADRAVVEGRFTTTDLDDATVAGLQAVLDSSGAERDEDGSV Rv1696|M.tuberculosis_H37Rv RADATRVRSGADRAVVEGRFTTTDLDDATVAGLQAVLDSSGAERDEDGSV MMAR_2501|M.marinum_M RADANRVRSGADRAIVEGRFTTVDLDQSATAHLDHMLDASGADRDEDGSV MUL_1685|M.ulcerans_Agy99 RADANRVRSGADRAIVEGRFTTVDLDQSATAHLDHMLDASGADRDEDGSV MAB_2361|M.abscessus_ATCC_1997 RADANRVRAGADRAVVEGRFLTADPLGAEPAEVTEVLDSSGAQRDDDGSV MSMEG_2423|M.smegmatis_MC2_155 QGAKTLRGGKMEDVIFAGTSSRAPLGRAEVT--LTIDNSDNALPIEYSEV :. . . : .:. * . . : :..: : . * Mvan_3288|M.vanbaalenii_PYR-1 IAARSVSRDGPSRAYLGGRSVPAKSLSGFTN--------ELLTLHGQNDQ Mflv_3507|M.gilvum_PYR-GCK IAARSVSRDGPSRAYLGGRSVPAKSLSGFTN--------ELLTLHGQNDQ TH_1548|M.thermoresistible__bu IAARTVSRDGPSRAYLGGRSVPAKSLGNFTG--------ELLTVHGQNDQ MLBr_01360|M.leprae_Br4923 IVLRSVSRDGPSRSYLGGRSVPAKSLGSFTT--------ELLALHGQNDQ MAV_3075|M.avium_104 IALRSVNRDGPSRAYLGGRSVPAKSLGDFTA--------ELLTLHGQNDQ Mb1722|M.bovis_AF2122/97 IALRSISRDGPSRAYLGGRGVPAKSLSGFTN--------ELLTLHGQNDQ Rv1696|M.tuberculosis_H37Rv IALRSISRDGPSRAYLGGRGVPAKSLSGFTN--------ELLTLHGQNDQ MMAR_2501|M.marinum_M IALRSVSSSGPSRAYLGGRSVPAKSLSNFTN--------ELLALHGQNDQ MUL_1685|M.ulcerans_Agy99 IALRSVSSSGPSRAYLGGRSVPAKSLSNFTN--------ELLALHGQNDQ MAB_2361|M.abscessus_ATCC_1997 IAARSVTSDGRSRAYLGGRSVPAKSLASFTA--------GLLTVHGQNDQ MSMEG_2423|M.smegmatis_MC2_155 SITRRMFRDGAGEYEINGASCRLMDVQELLSDSGIGREMHVIVGQGKLSE * : .* .. :.* . .: : ::. :*: .: Mvan_3288|M.vanbaalenii_PYR-1 LRLMRPDEQRAALDRYA--------------DVATQLHRYRTARDSWLEA Mflv_3507|M.gilvum_PYR-GCK LRLMRPDEQRNALDRYA--------------DVTRRLDRYRSARDAWLEA TH_1548|M.thermoresistible__bu LRLMRPDEQRAALDRFA--------------DLGGRLQRYQLLHQQWLDA MLBr_01360|M.leprae_Br4923 LRLVRPEEQRAALDRYA--------------AAGPSCERYRELRDAWLLA MAV_3075|M.avium_104 LRLMRPEEQCGALDRFA--------------KAGPALERYTKLRDAWLSA Mb1722|M.bovis_AF2122/97 LRLMRPDEQRGALDRFA--------------AAGEAVQRYRKLRDAWLTA Rv1696|M.tuberculosis_H37Rv LRLMRPDEQRGALDRFA--------------AAGEAVQRYRKLRDAWLTA MMAR_2501|M.marinum_M LRLMRPEEQRGALDRFA--------------TSASALQRYRKLRDTWLSA MUL_1685|M.ulcerans_Agy99 LRLMRPEEQRGALDRFA--------------TSASALQRYRKLRDTWLSA MAB_2361|M.abscessus_ATCC_1997 LRLMRPEQQLAALDKFASD------------SIEALLTTYRKLREEWLAA MSMEG_2423|M.smegmatis_MC2_155 ILESRPEDRRAFIEEAAGVLKHRKRKEKAVRKLDSMAANLARLTDLTTEL : **::: ::. * : Mvan_3288|M.vanbaalenii_PYR-1 KRDLD--------DRRRRAREMAQEADRLQFALNEIDVIDPHSGEDDALV Mflv_3507|M.gilvum_PYR-GCK RRDLE--------DRRRRTRELAQEADRLHFALNEIDVVDPKPGEDEALV TH_1548|M.thermoresistible__bu RRDLA--------DRRERARELAQEADRLTFALNEIDAVAPQPGEDDALA MLBr_01360|M.leprae_Br4923 RSDLI--------DRRNRIRELVQEADRLKFALSEIDSVDPQPGEDNALV MAV_3075|M.avium_104 RRDLA--------DRRNRMRELALEADRLTFALGEIDAVDPQPGEDDALV Mb1722|M.bovis_AF2122/97 RRDLV--------DRRNRARELAQEADRLKFALNEIDTVDPQPGEDVALV Rv1696|M.tuberculosis_H37Rv RRDLV--------DRRNRARELAQEADRLKFALNEIDTVDPQPGEDVALV MMAR_2501|M.marinum_M RRDLL--------DRRNRARELAQEADRLQFALDEIDTVDPQPGEDDALV MUL_1685|M.ulcerans_Agy99 RRDLL--------DRRNRARELAQEADRLQFALDEIDTVDPQPGEDDALV MAB_2361|M.abscessus_ATCC_1997 RRDLI--------DRTNRVRELAQEADRLGFALNEIDTVDPKPGEDDQLT MSMEG_2423|M.smegmatis_MC2_155 RRQLKPLGRQAEMARRAATIQADLRDARLRLAADDLVRRQVEFQNTNQAE : :* * : . ** :* .:: . : Mvan_3288|M.vanbaalenii_PYR-1 AEIRRLSELDALREAVQTARAALSGE-SDD----GFSAAHAVGQARSALE Mflv_3507|M.gilvum_PYR-GCK ADIRRLSELDALRDAVQTARAALAGD-GDDSAHDGFSAAGAVGQARSALE TH_1548|M.thermoresistible__bu ENIRRLSELDALREAARTARARLSGALDDDAAVDATSALDQVGQAKAALE MLBr_01360|M.leprae_Br4923 ADIVRLSELDMLREVAVNARAALSGA-LDDMDVSGSNAVACMGQAKAALE MAV_3075|M.avium_104 AEIMRLSELDTLREAAAAARAALS---ADDADGSGLSAVDTLGKARAALE Mb1722|M.bovis_AF2122/97 ADIARLSELDTLREAATTARATLCG--TPDADAFDRGAVDSLGRARAALQ Rv1696|M.tuberculosis_H37Rv ADIARLSELDTLREAATTARATLCG--TPDADAFDRGAVDSLGRARAALQ MMAR_2501|M.marinum_M ADIARLSELDTLREAASAARAALSG---ASEEAFGTGAAECLGRARAALE MUL_1685|M.ulcerans_Agy99 ADIARLSELDTLREAASAARAALSG---ASEEAFGTGAAECLGRARAALE MAB_2361|M.abscessus_ATCC_1997 ADIHRLSELDALRDAAASAREALAGADADGDAHDSHSAIDRIARAKALVE MSMEG_2423|M.smegmatis_MC2_155 TALRKEHEELTVRLQSATVELQAHEAAVAELTRRAEAAQQTWFRASALAE : : * :* .. * :* : : Mvan_3288|M.vanbaalenii_PYR-1 --------GTDDAPLKALAEQLG-----SALTVLVDVSAELG-GYLDELP Mflv_3507|M.gilvum_PYR-GCK --------NTDDVALKSLAEQLG-----AALTVVVDVSAELG-HFLAELP TH_1548|M.thermoresistible__bu --------STDDTALRALGARLD-----EALLLIGDVADELG-GYLEGLP MLBr_01360|M.leprae_Br4923 --------STDDATLRAFADQVG-----EVLTVVVEVGRELG-EYLEELP MAV_3075|M.avium_104 --------STDDPKLLALAGQIG-----EVLTVVVDAAGELA-GFLEELP Mb1722|M.bovis_AF2122/97 --------SSDDAALRGLAEQVG-----EALTVVVDAVAELG-AYLDELP Rv1696|M.tuberculosis_H37Rv --------SSDDAALRGLAEQVG-----EALTVVVDAVAELG-AYLDELP MMAR_2501|M.marinum_M --------SSDDATLQALAKQVS-----DALAVVSDAAGELG-SYVDALP MUL_1685|M.ulcerans_Agy99 --------SSDDATLQALAKQVS-----DALAVVSDAAGELG-SYVDALP MAB_2361|M.abscessus_ATCC_1997 --------ATDDATLRALAPQLA-----EALAVVSDVSRELT-AFTDELP MSMEG_2423|M.smegmatis_MC2_155 RVGATVRIATDRAQMLDSEPEMSSGRDPDALEAEAEEVAELEAQLLDELS :* : .: .* : ** *. Mvan_3288|M.vanbaalenii_PYR-1 TDTSSLETKLARQAELRTLTRKYAADVDGVLAWAGEARDRLA----ALDV Mflv_3507|M.gilvum_PYR-GCK SDASTLETKLARQAELRTLTRKYAADIDGVLAWAVEARERLS----ALDV TH_1548|M.thermoresistible__bu TDASTLETSLARQSELRTLTRKYAADIDGVLQWAQQARDRLA----QLDV MLBr_01360|M.leprae_Br4923 VDASALESKLVRQAELCTLTRKYAADIDGVLQWARESRERLE----QLDV MAV_3075|M.avium_104 VDASALEAKLARQSELRGLTRKYAADIDGVLAWARESRERLA----QLDV Mb1722|M.bovis_AF2122/97 ADASALDAKLARQAQLRTLTRKYAADIDGVLRWADEARARLA----QLDV Rv1696|M.tuberculosis_H37Rv ADASALDAKLARQAQLRTLTRKYAADIDGVLRWADEARARLA----QLDV MMAR_2501|M.marinum_M ADASALDTKLARQAQLRTLTRKYAADIDGVLAWAQDSRARLA----ALDV MUL_1685|M.ulcerans_Agy99 ADASALDTKLARQAQLRTLTRKYAADIDGVLAWAQDSRARLA----ALDV MAB_2361|M.abscessus_ATCC_1997 SDASTLEEKLARQGQLRTLTRKYAADLNGVIAWAKEARTRLA----EVDT MSMEG_2423|M.smegmatis_MC2_155 EARIALETARAELAEREQIAADAERAHMAAARAEADRREGLARLAGQVDT :*: .. .: :: . .. : * * :*. Mvan_3288|M.vanbaalenii_PYR-1 SEETLAGLERRVEELQATVVAAAQDLTKVRVKAAKGLSKAVTAELSGLAM Mflv_3507|M.gilvum_PYR-GCK SEETLTGLQRRVDELQSAVVAAAQDVTKVRSKAAKGLSKAVTAELAGLAM TH_1548|M.thermoresistible__bu SEEALGELERRVDELQAQVVSAAMDLTKARTRAAGRLAKAVTAELAGLAM MLBr_01360|M.leprae_Br4923 SYERLAGVESRVDELERQLSQAAVDLSKLRRDAANRLAKEVTAELSALAM MAV_3075|M.avium_104 SEEGLSALAARVEELGRELAGAAADLSTIRRKAAKRLAKEVTAELSGLAM Mb1722|M.bovis_AF2122/97 SEEGLAALERRTGELAHELGQAAVDLSTIRRKAAKRLAKEVSAELSALAM Rv1696|M.tuberculosis_H37Rv SEEGLAALERRTGELAHELGQAAVDLSTIRRKAAKRLAKEVSAELSALAM MMAR_2501|M.marinum_M SEEGLAALQRRAGELEHEVAQAAAELSKTRARAAKRLAKEVTAELSALAM MUL_1685|M.ulcerans_Agy99 SEEGLAALQRRAGELEHEVAQAAAELSKTRAKAAKRLAKEVTAELSALAM MAB_2361|M.abscessus_ATCC_1997 SEETLNAIAARVDRLGAELATAATGLSKARAKAAKALSKAVTAELAGLAM MSMEG_2423|M.smegmatis_MC2_155 MRTRVESIDEGVLRLSVSIEEAAAKAEHAQAEFEDVQSRVGELDAGEVGL : : . .* : ** : :: : . :.: Mvan_3288|M.vanbaalenii_PYR-1 AGADFAISVTPLPARA----DDSAPLALPSGVTVHAGHDGVDAVEFGFAA Mflv_3507|M.gilvum_PYR-GCK SGAQFAITVAPLAARA----DDSAPLELPSGVTVHAGRDGVDAVEFGFAA TH_1548|M.thermoresistible__bu ADAEFTVTVGPLTARP----DDTAPLTMPDGQTVHAGRHGVDGVEFGFTA MLBr_01360|M.leprae_Br4923 VDAEFTISVTTDLIPL-TDYKRSAAVTLPSGGVARAGADGVDQVEFGFAA MAV_3075|M.avium_104 ADAQFSIDVSTDVVPAGSGSDDAAVLTLPSGERVRAGADGIDQVEFGFAA Mb1722|M.bovis_AF2122/97 ADAEFTIGVTTELADH----GDPVALALASGELARAGADGVDAVEFGFVA Rv1696|M.tuberculosis_H37Rv ADAEFTIGVTTELADH----GDPVALALASGELARAGADGVDAVEFGFVA MMAR_2501|M.marinum_M ADAEFTIAVGVEVADE----DDAAALTLPTGERVRAGGDGVDLVEFGFAA MUL_1685|M.ulcerans_Agy99 ADAEFTIVVGVEVADE----DDAAALTLPTGERVRAGGDGVDLVEFGFAA MAB_2361|M.abscessus_ATCC_1997 DRAAFSIGVEPIAARP----DDSAPLTLPSGQTVHAGSSGTDVVEFGFAA MSMEG_2423|M.smegmatis_MC2_155 DEHHDRTVAALRLADER--VAELQAAERAAERQVASLRARIEALSVGLDR . . . : : :..*: Mvan_3288|M.vanbaalenii_PYR-1 HGGSDLLPLNKSASG-----GELSRVMLALEVVLSAS------------T Mflv_3507|M.gilvum_PYR-GCK HGGSDLLPLNKSASG-----GELSRVMLALEVVLSAS------------T TH_1548|M.thermoresistible__bu HRGTDVLPLAKSASG-----GELSRVMLALEVVLAAS------------A MLBr_01360|M.leprae_Br4923 HRGMTVLPLAKSASG-----GELSRVMLALEVVLATS------------A MAV_3075|M.avium_104 HRGMDRLPLAKSASG-----GELSRVMLALEVVLAASR---------KET Mb1722|M.bovis_AF2122/97 HRGMTVLPLAKSASG-----GELSRVMLSLEVVLATSR---------KQA Rv1696|M.tuberculosis_H37Rv HRGMTVLPLAKSASG-----GELSRVMLSLEVVLATSR---------KQA MMAR_2501|M.marinum_M HRGMTVLPLAKSASG-----GELSRVMLALEVVLAAS------------A MUL_1685|M.ulcerans_Agy99 HRGMTVLPLAKSASG-----GELSRVMLALEVVLAAS------------A MAB_2361|M.abscessus_ATCC_1997 HRDNPMLPLAKSASG-----GELSRVMLALEVVLAAS------------T MSMEG_2423|M.smegmatis_MC2_155 RDGAAWLQKNHSGGGLFGSIGDFLRVQPGYEVAVAAVLGAAADALAAENF : . * :*..* *:: ** . **.::: Mvan_3288|M.vanbaalenii_PYR-1 EGTTMVFDEVDAGVGGRAAVQIGRR--------------------LARLA Mflv_3507|M.gilvum_PYR-GCK EGTTMVFDEVDAGVGGRAAVQIGRR--------------------LARLA TH_1548|M.thermoresistible__bu EGTTMVFDEVDAGVGGRAAVQIGRR--------------------LARLA MLBr_01360|M.leprae_Br4923 AGTTMVFDEVDVGVGGRAAVQIGRR--------------------LARLA MAV_3075|M.avium_104 VGTTMVFDEVDAGVGGRAAVQIGRR--------------------LARLA Mb1722|M.bovis_AF2122/97 AGTTMVFDEIDAGVGGWAAVQIGRR--------------------LARLA Rv1696|M.tuberculosis_H37Rv AGTTMVFDEIDAGVGGWAAVQIGRR--------------------LARLA MMAR_2501|M.marinum_M AGTTMVFDEVDAGVGGWAAVQIGRR--------------------LARLA MUL_1685|M.ulcerans_Agy99 AGTTMVFDEVDAGVGGWAAVQIGRR--------------------LARLA MAB_2361|M.abscessus_ATCC_1997 AGTTMVFDEVDAGVGGRAAVQIGRR--------------------LAKLA MSMEG_2423|M.smegmatis_MC2_155 GAAAAAVAALKESDGGRAAIVLGDWNAIGSSPQAALPPGATWATDLVSVP .:: .. :. . ** **: :* *. :. Mvan_3288|M.vanbaalenii_PYR-1 RTHQVIVVTHLPQVAAYADVHLVVEGV----------------------- Mflv_3507|M.gilvum_PYR-GCK RTHQVIVVTHLPQVAAYADVHLVVEGVGN--------------------- TH_1548|M.thermoresistible__bu RTHQVIVVTHLPQVAAYADIHLVVDSG----------------------- MLBr_01360|M.leprae_Br4923 RTHQVIVVTHLPQVAAYADVHLVVHSAG---------------------- MAV_3075|M.avium_104 RTHQVIVVTHLPQVAAYADVHLVVHGAG---------------------- Mb1722|M.bovis_AF2122/97 RTHQVIVVTHLPQVAAYADVHLMVQRTG---------------------- Rv1696|M.tuberculosis_H37Rv RTHQVIVVTHLPQVAAYADVHLMVQRTG---------------------- MMAR_2501|M.marinum_M RTHQVIVVTHLPQVAAYADVHLMVHGT----------------------- MUL_1685|M.ulcerans_Agy99 RTHQVIVVTHLPQVAAYADVHLMVHGT----------------------- MAB_2361|M.abscessus_ATCC_1997 HTHQVIVVTHLPQVAAFADIHLTVDRVN---------------------- MSMEG_2423|M.smegmatis_MC2_155 DRLRGAVTAMLTGVAVVPDMAAGLALVSSRPELRAVTTEGDLVGPGWVSG : *.: *. **. .*: : Mvan_3288|M.vanbaalenii_PYR-1 ----AGRDDGRKARAKSSGVRRLDDDDRVAELARMLAGLGESDSGRAHAR Mflv_3507|M.gilvum_PYR-GCK --DGAGSGDGKKARAKSSGVRRLDDDDRVAELARMLAGLGESDSGRAHAR TH_1548|M.thermoresistible__bu -----GRDADNRG---ASRVQRLDEEGRVAELARMLAGLGETDSGRAHAR MLBr_01360|M.leprae_Br4923 -------------LDGASDVRRLAGDDRVAELARMLAGLGESDSGRAHAR MAV_3075|M.avium_104 -------------PRGTSVVRRVTGDERVAELARMLAGLGESDSGRAHAR Mb1722|M.bovis_AF2122/97 -------------RDGASGVRRLTSEDRVAELARMLAGLGDSDSGRAHAR Rv1696|M.tuberculosis_H37Rv -------------RDGASGVRRLTSEDRVAELARMLAGLGDSDSGRAHAR MMAR_2501|M.marinum_M -------------KGGASEVRRLSDDERVGELARMLAGLGESDSGRAHAR MUL_1685|M.ulcerans_Agy99 -------------KGGASEVRRLSDDERVGELARMLAGLGESDSGRAHAR MAB_2361|M.abscessus_ATCC_1997 --------------SKGSGVRRLDDEDRVAELARMLAGLGDSDTGRAHAR MSMEG_2423|M.smegmatis_MC2_155 GSDRKPSTLEIASEIDKARAELEQAERQTSELGAALSGALAEQSARQDAA : .. : :..**. *:* ::.* .* Mvan_3288|M.vanbaalenii_PYR-1 ELLDAARAERAAAD------------------------------------ Mflv_3507|M.gilvum_PYR-GCK DLLDAARKDRAAE------------------------------------- TH_1548|M.thermoresistible__bu ELLEAAQRERAEVSV----------------------------------- MLBr_01360|M.leprae_Br4923 ELLDAARKDKS--------------------------------------- MAV_3075|M.avium_104 ELLDAAQKDEI--------------------------------------- Mb1722|M.bovis_AF2122/97 ELLETAQNDELT-------------------------------------- Rv1696|M.tuberculosis_H37Rv ELLETAQNDELT-------------------------------------- MMAR_2501|M.marinum_M ELLDTARNDKD--------------------------------------- MUL_1685|M.ulcerans_Agy99 ELLDTARNDKD--------------------------------------- MAB_2361|M.abscessus_ATCC_1997 ELLDAARAERT--------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 EQALAALNESDAAISAIYEQLARLGQEARGAHQEWQRLIKQRDELEAGRT : :* : Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 KTVEELRELESRLSNAEQTPMFDIEPVDRQETVAAAEAARAVEVEARLAV Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 RTAEERANAVRGRADSLRRAAAAEREARVRAQRAREAREYAARVAAAVSE Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 CGRQIAGKLSAVVAAAARSRDELATERQLRVNALGEIREEVTALNNRINT Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 LTDALHRDEMAKAQAQLRIEQLEAQVLEQFGMSAGDLVAEYGPQVALPPS Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 ELEMAEYEQAKERGEQVTAPAPMPFDRATQERRAKRAERELAELGRVNPL Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 ALEEFAALEERYNFLSTQLEDVKAARADLLDVIADVDNRILQVFTEAYAD Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 VEREFEQVFATLFPGGEGRLLLTDPSDMLTTGIEVEARPPGKKIKRLSLL Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 SGGEKSLTAVAMLVAIFRARPSPFYVMDEVEAALDDVNLRRLISLFEQLR Mvan_3288|M.vanbaalenii_PYR-1 ------------------------------------------------- Mflv_3507|M.gilvum_PYR-GCK ------------------------------------------------- TH_1548|M.thermoresistible__bu ------------------------------------------------- MLBr_01360|M.leprae_Br4923 ------------------------------------------------- MAV_3075|M.avium_104 ------------------------------------------------- Mb1722|M.bovis_AF2122/97 ------------------------------------------------- Rv1696|M.tuberculosis_H37Rv ------------------------------------------------- MMAR_2501|M.marinum_M ------------------------------------------------- MUL_1685|M.ulcerans_Agy99 ------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 ------------------------------------------------- MSMEG_2423|M.smegmatis_MC2_155 EKSQLIVITHQKPTMEIADALYGVTMRGDGITTVISQRMRGQELVSNPS