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LTEIRIESLGAISAAVGEFDRGLTVLTGETGTGKTMVVTGLHLLGGARADATRVRSGADRAIVEGRFTTT DLDEALVVRLDEMLDASGAERDEDGSVIALRSVNRDGPSRAYLGGRSVPAKSLGDFTAELLTLHGQNDQL RLMRPEEQCGALDRFAKAGPALERYTKLRDAWLSARRDLADRRNRMRELALEADRLTFALGEIDAVDPQP GEDDALVAEIMRLSELDTLREAAAAARAALSADDADGSGLSAVDTLGKARAALESTDDPKLLALAGQIGE VLTVVVDAAGELAGFLEELPVDASALEAKLARQSELRGLTRKYAADIDGVLAWARESRERLAQLDVSEEG LSALAARVEELGRELAGAAADLSTIRRKAAKRLAKEVTAELSGLAMADAQFSIDVSTDVVPAGSGSDDAA VLTLPSGERVRAGADGIDQVEFGFAAHRGMDRLPLAKSASGGELSRVMLALEVVLAASRKETVGTTMVFD EVDAGVGGRAAVQIGRRLARLARTHQVIVVTHLPQVAAYADVHLVVHGAGPRGTSVVRRVTGDERVAELA RMLAGLGESDSGRAHARELLDAAQKDEI*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_3075 | recN | - | 100% (589) | DNA repair protein RecN |
M. avium 104 | MAV_3777 | smc | 2e-09 | 22.82% (447) | chromosome segregation protein SMC |
M. avium 104 | MAV_3135 | uvrA | 5e-07 | 26.30% (308) | excinuclease ABC subunit A |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1722 | recN | 0.0 | 76.78% (590) | DNA repair protein recN (recombination protein N) |
M. gilvum PYR-GCK | Mflv_3507 | - | 0.0 | 70.88% (601) | DNA repair protein RecN |
M. tuberculosis H37Rv | Rv1696 | recN | 0.0 | 76.78% (590) | DNA repair protein recN (recombination protein N) |
M. leprae Br4923 | MLBr_01360 | recN | 0.0 | 77.29% (590) | recombination and DNA repair |
M. abscessus ATCC 19977 | MAB_2361 | - | 0.0 | 68.75% (592) | DNA repair protein RecN |
M. marinum M | MMAR_2501 | recN | 0.0 | 77.38% (588) | DNA repair protein, RecN |
M. smegmatis MC2 155 | MSMEG_3808 | uvrA | 2e-07 | 27.18% (298) | excinuclease ABC subunit A |
M. thermoresistible (build 8) | TH_1548 | recN | 0.0 | 70.88% (594) | PROBABLE DNA REPAIR PROTEIN RECN (RECOMBINATION PROTEIN N) |
M. ulcerans Agy99 | MUL_1685 | recN | 0.0 | 77.55% (588) | DNA repair protein, RecN |
M. vanbaalenii PYR-1 | Mvan_3288 | - | 0.0 | 71.09% (595) | DNA repair protein RecN |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3507|M.gilvum_PYR-GCK MLAEIRIEALGAINAATAEFDG---GLTVLTGETGAGKTMVVTGLHLLGG Mvan_3288|M.vanbaalenii_PYR-1 MLAEIRIEALGAISAATAEFDG---GLTVLTGETGAGKTMVVTGLHLLGG TH_1548|M.thermoresistible__bu VLSEIRIESLGAISSATAEFDR---GLTVLTGETGTGKTMVVTGLHLLGG Mb1722|M.bovis_AF2122/97 MLTELRIESLGAISVATAEFDR---GFTVLTGETGTGKTMVVTGLHLLGG Rv1696|M.tuberculosis_H37Rv MLTELRIESLGAISVATAEFDR---GFTVLTGETGTGKTMVVTGLHLLGG MMAR_2501|M.marinum_M MLTEIRIESLGAISAATAEFDR---GLTVLTGETGTGKTMVVTGLHLLGG MUL_1685|M.ulcerans_Agy99 MLTEIRIESLGAISAATAEFDR---GLTVLTGETGTGKTMVVTGLHLLGG MAV_3075|M.avium_104 MLTEIRIESLGAISAAVGEFDR---GLTVLTGETGTGKTMVVTGLHLLGG MLBr_01360|M.leprae_Br4923 MLTEIRIESLGAISVATAEFDR---GLTVLTGETGTGKTMVVTGLHLLGG MAB_2361|M.abscessus_ATCC_1997 MLTEIRIESLGAIPAATAEFDS---GLTVLTGETGAGKTMVVTSLHLLGG MSMEG_3808|M.smegmatis_MC2_155 MADRLVVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEG : .: ::. ::* .: *:** :*:**: :. . : * Mflv_3507|M.gilvum_PYR-GCK ARADATKVRSGSDRAVVEGRFTTTEVGDAVSARVDGILDSSGAE-RDDDG Mvan_3288|M.vanbaalenii_PYR-1 ARADATKVRSGADRAVVEGRFTTAEVGDAVAAQVDGILDSSGAE-RDDDG TH_1548|M.thermoresistible__bu GRADPTRVRSGAQRAVVEGRFSTAELLDEAAARVDDILAASGAE-RDEDG Mb1722|M.bovis_AF2122/97 ARADATRVRSGADRAVVEGRFTTTDLDDATVAGLQAVLDSSGAE-RDEDG Rv1696|M.tuberculosis_H37Rv ARADATRVRSGADRAVVEGRFTTTDLDDATVAGLQAVLDSSGAE-RDEDG MMAR_2501|M.marinum_M ARADANRVRSGADRAIVEGRFTTVDLDQSATAHLDHMLDASGAD-RDEDG MUL_1685|M.ulcerans_Agy99 ARADANRVRSGADRAIVEGRFTTVDLDQSATAHLDHMLDASGAD-RDEDG MAV_3075|M.avium_104 ARADATRVRSGADRAIVEGRFTTTDLDEALVVRLDEMLDASGAE-RDEDG MLBr_01360|M.leprae_Br4923 ARADASRVRSGANRAVVEGRFTTTDLDDVVVAQLDGILNASGSE-RDEDG MAB_2361|M.abscessus_ATCC_1997 ARADANRVRAGADRAVVEGRFLTADPLGAEPAEVTEVLDSSGAQ-RDDDG MSMEG_3808|M.smegmatis_MC2_155 QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG * : : : : : : .: : ::. : *. * Mflv_3507|M.gilvum_PYR-GCK SVIAARSVS-----RDGPSRAYLGGRSVPAKSLSGFTNELLTLHG--QND Mvan_3288|M.vanbaalenii_PYR-1 SVIAARSVS-----RDGPSRAYLGGRSVPAKSLSGFTNELLTLHG--QND TH_1548|M.thermoresistible__bu TVIAARTVS-----RDGPSRAYLGGRSVPAKSLGNFTGELLTVHG--QND Mb1722|M.bovis_AF2122/97 SVIALRSIS-----RDGPSRAYLGGRGVPAKSLSGFTNELLTLHG--QND Rv1696|M.tuberculosis_H37Rv SVIALRSIS-----RDGPSRAYLGGRGVPAKSLSGFTNELLTLHG--QND MMAR_2501|M.marinum_M SVIALRSVS-----SSGPSRAYLGGRSVPAKSLSNFTNELLALHG--QND MUL_1685|M.ulcerans_Agy99 SVIALRSVS-----SSGPSRAYLGGRSVPAKSLSNFTNELLALHG--QND MAV_3075|M.avium_104 SVIALRSVN-----RDGPSRAYLGGRSVPAKSLGDFTAELLTLHG--QND MLBr_01360|M.leprae_Br4923 SVIVLRSVS-----RDGPSRSYLGGRSVPAKSLGSFTTELLALHG--QND MAB_2361|M.abscessus_ATCC_1997 SVIAARSVT-----SDGRSRAYLGGRSVPAKSLASFTAGLLTVHG--QND MSMEG_3808|M.smegmatis_MC2_155 TITEVYDYLRLLYARAGTPHCPVCGERIARQTPQQIVDQVLAMDEGLRFQ :: * .:. : *. :. :: :. :*::. : : Mflv_3507|M.gilvum_PYR-GCK QLRLMRPDEQRNALDRYA---------------------------DVTRR Mvan_3288|M.vanbaalenii_PYR-1 QLRLMRPDEQRAALDRYA---------------------------DVATQ TH_1548|M.thermoresistible__bu QLRLMRPDEQRAALDRFA---------------------------DLGGR Mb1722|M.bovis_AF2122/97 QLRLMRPDEQRGALDRFA---------------------------AAGEA Rv1696|M.tuberculosis_H37Rv QLRLMRPDEQRGALDRFA---------------------------AAGEA MMAR_2501|M.marinum_M QLRLMRPEEQRGALDRFA---------------------------TSASA MUL_1685|M.ulcerans_Agy99 QLRLMRPEEQRGALDRFA---------------------------TSASA MAV_3075|M.avium_104 QLRLMRPEEQCGALDRFA---------------------------KAGPA MLBr_01360|M.leprae_Br4923 QLRLVRPEEQRAALDRYA---------------------------AAGPS MAB_2361|M.abscessus_ATCC_1997 QLRLMRPEQQLAALDKFASD-------------------------SIEAL MSMEG_3808|M.smegmatis_MC2_155 VLAPVVRTRKGEFVDLFEKLNSQGYSRVRVDGVVYPLTDPPKLKKQEKHD * : .: :* : Mflv_3507|M.gilvum_PYR-GCK LDRYRSARDAWLEARRDLEDRRRRTRELAQEADRLHFALNEIDVVDPKPG Mvan_3288|M.vanbaalenii_PYR-1 LHRYRTARDSWLEAKRDLDDRRRRAREMAQEADRLQFALNEIDVIDPHSG TH_1548|M.thermoresistible__bu LQRYQLLHQQWLDARRDLADRRERARELAQEADRLTFALNEIDAVAPQPG Mb1722|M.bovis_AF2122/97 VQRYRKLRDAWLTARRDLVDRRNRARELAQEADRLKFALNEIDTVDPQPG Rv1696|M.tuberculosis_H37Rv VQRYRKLRDAWLTARRDLVDRRNRARELAQEADRLKFALNEIDTVDPQPG MMAR_2501|M.marinum_M LQRYRKLRDTWLSARRDLLDRRNRARELAQEADRLQFALDEIDTVDPQPG MUL_1685|M.ulcerans_Agy99 LQRYRKLRDTWLSARRDLLDRRNRARELAQEADRLQFALDEIDTVDPQPG MAV_3075|M.avium_104 LERYTKLRDAWLSARRDLADRRNRMRELALEADRLTFALGEIDAVDPQPG MLBr_01360|M.leprae_Br4923 CERYRELRDAWLLARSDLIDRRNRIRELVQEADRLKFALSEIDSVDPQPG MAB_2361|M.abscessus_ATCC_1997 LTTYRKLREEWLAARRDLIDRTNRVRELAQEADRLGFALNEIDTVDPKPG MSMEG_3808|M.smegmatis_MC2_155 IEVVVDRLTVKASAKQRLTDSIETALNLADGIVVLEFVDREDDHPHREQR *: * * . ::. * *. * * . Mflv_3507|M.gilvum_PYR-GCK EDEALVADIRRLSELDALRDAVQTARAALAGD-GDDSAHDGFSAAGAVGQ Mvan_3288|M.vanbaalenii_PYR-1 EDDALVAEIRRLSELDALREAVQTARAALSGE-SDD----GFSAAHAVGQ TH_1548|M.thermoresistible__bu EDDALAENIRRLSELDALREAARTARARLSGALDDDAAVDATSALDQVGQ Mb1722|M.bovis_AF2122/97 EDVALVADIARLSELDTLREAATTARATLCG--TPDADAFDRGAVDSLGR Rv1696|M.tuberculosis_H37Rv EDVALVADIARLSELDTLREAATTARATLCG--TPDADAFDRGAVDSLGR MMAR_2501|M.marinum_M EDDALVADIARLSELDTLREAASAARAALSG---ASEEAFGTGAAECLGR MUL_1685|M.ulcerans_Agy99 EDDALVADIARLSELDTLREAASAARAALSG---ASEEAFGTGAAECLGR MAV_3075|M.avium_104 EDDALVAEIMRLSELDTLREAAAAARAALS---ADDADGSGLSAVDTLGK MLBr_01360|M.leprae_Br4923 EDNALVADIVRLSELDMLREVAVNARAALSGA-LDDMDVSGSNAVACMGQ MAB_2361|M.abscessus_ATCC_1997 EDDQLTADIHRLSELDALRDAAASAREALAGADADGDAHDSHSAIDRIAR MSMEG_3808|M.smegmatis_MC2_155 FSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECTGLGIRKEVDPDLVV . *. : :* *. . . : Mflv_3507|M.gilvum_PYR-GCK ARSALENTDDVALKSLAEQLGAALTVVVDVSAELGHFLAELPSDASTLET Mvan_3288|M.vanbaalenii_PYR-1 ARSALEGTDDAPLKALAEQLGSALTVLVDVSAELGGYLDELPTDTSSLET TH_1548|M.thermoresistible__bu AKAALESTDDTALRALGARLDEALLLIGDVADELGGYLEGLPTDASTLET Mb1722|M.bovis_AF2122/97 ARAALQSSDDAALRGLAEQVGEALTVVVDAVAELGAYLDELPADASALDA Rv1696|M.tuberculosis_H37Rv ARAALQSSDDAALRGLAEQVGEALTVVVDAVAELGAYLDELPADASALDA MMAR_2501|M.marinum_M ARAALESSDDATLQALAKQVSDALAVVSDAAGELGSYVDALPADASALDT MUL_1685|M.ulcerans_Agy99 ARAALESSDDATLQALAKQVSDALAVVSDAAGELGSYVDALPADASALDT MAV_3075|M.avium_104 ARAALESTDDPKLLALAGQIGEVLTVVVDAAGELAGFLEELPVDASALEA MLBr_01360|M.leprae_Br4923 AKAALESTDDATLRAFADQVGEVLTVVVEVGRELGEYLEELPVDASALES MAB_2361|M.abscessus_ATCC_1997 AKALVEATDDATLRALAPQLAEALAVVSDVSRELTAFTDELPSDASTLEE MSMEG_3808|M.smegmatis_MC2_155 PDPELTLAEGAVAPWSVGQSAEYFTRMLAGLGEEMGFDVNTPWKKLPAKA . . : ::. : : : * : * . . . Mflv_3507|M.gilvum_PYR-GCK K-----------LARQAELRTLTRKYAADIDGVLAWAVEARERLSALDVS Mvan_3288|M.vanbaalenii_PYR-1 K-----------LARQAELRTLTRKYAADVDGVLAWAGEARDRLAALDVS TH_1548|M.thermoresistible__bu S-----------LARQSELRTLTRKYAADIDGVLQWAQQARDRLAQLDVS Mb1722|M.bovis_AF2122/97 K-----------LARQAQLRTLTRKYAADIDGVLRWADEARARLAQLDVS Rv1696|M.tuberculosis_H37Rv K-----------LARQAQLRTLTRKYAADIDGVLRWADEARARLAQLDVS MMAR_2501|M.marinum_M K-----------LARQAQLRTLTRKYAADIDGVLAWAQDSRARLAALDVS MUL_1685|M.ulcerans_Agy99 K-----------LARQAQLRTLTRKYAADIDGVLAWAQDSRARLAALDVS MAV_3075|M.avium_104 K-----------LARQSELRGLTRKYAADIDGVLAWARESRERLAQLDVS MLBr_01360|M.leprae_Br4923 K-----------LVRQAELCTLTRKYAADIDGVLQWARESRERLEQLDVS MAB_2361|M.abscessus_ATCC_1997 K-----------LARQGQLRTLTRKYAADLNGVIAWAKEARTRLAEVDTS MSMEG_3808|M.smegmatis_MC2_155 RRAILEGCDHQVHVRYKNRYGRTRSYYADFEGVMAFLQRRMEQTDSEQMK .* : **.* **.:**: : : : . Mflv_3507|M.gilvum_PYR-GCK E------ETLTGLQRRVDELQSAVVAAAQDVTKVRSKAAKGLSKAVTAEL Mvan_3288|M.vanbaalenii_PYR-1 E------ETLAGLERRVEELQATVVAAAQDLTKVRVKAAKGLSKAVTAEL TH_1548|M.thermoresistible__bu E------EALGELERRVDELQAQVVSAAMDLTKARTRAAGRLAKAVTAEL Mb1722|M.bovis_AF2122/97 E------EGLAALERRTGELAHELGQAAVDLSTIRRKAAKRLAKEVSAEL Rv1696|M.tuberculosis_H37Rv E------EGLAALERRTGELAHELGQAAVDLSTIRRKAAKRLAKEVSAEL MMAR_2501|M.marinum_M E------EGLAALQRRAGELEHEVAQAAAELSKTRARAAKRLAKEVTAEL MUL_1685|M.ulcerans_Agy99 E------EGLAALQRRAGELEHEVAQAAAELSKTRAKAAKRLAKEVTAEL MAV_3075|M.avium_104 E------EGLSALAARVEELGRELAGAAADLSTIRRKAAKRLAKEVTAEL MLBr_01360|M.leprae_Br4923 Y------ERLAGVESRVDELERQLSQAAVDLSKLRRDAANRLAKEVTAEL MAB_2361|M.abscessus_ATCC_1997 E------ETLNAIAARVDRLGAELATAATGLSKARAKAAKALSKAVTAEL MSMEG_3808|M.smegmatis_MC2_155 ERYEGFMRDIPCPECNGTRLKPEILAVTLSAGDFGAKSIAQVAELSIADC . : . .* : .: : ::: *: Mflv_3507|M.gilvum_PYR-GCK AGLA---------------------------------------------- Mvan_3288|M.vanbaalenii_PYR-1 SGLA---------------------------------------------- TH_1548|M.thermoresistible__bu AGLA---------------------------------------------- Mb1722|M.bovis_AF2122/97 SALA---------------------------------------------- Rv1696|M.tuberculosis_H37Rv SALA---------------------------------------------- MMAR_2501|M.marinum_M SALA---------------------------------------------- MUL_1685|M.ulcerans_Agy99 SALA---------------------------------------------- MAV_3075|M.avium_104 SGLA---------------------------------------------- MLBr_01360|M.leprae_Br4923 SALA---------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 AGLA---------------------------------------------- MSMEG_3808|M.smegmatis_MC2_155 ADFLNSLTLGPREQAIAGQVLKEIQSRLGFLLDVGLDYLSLSRAAATLSG : : Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_3808|M.smegmatis_MC2_155 GEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIDTLVRLRDLGN Mflv_3507|M.gilvum_PYR-GCK -----------MSGAQFAITVAPLAARA----------DDSAPLELPSGV Mvan_3288|M.vanbaalenii_PYR-1 -----------MAGADFAISVTPLPARA----------DDSAPLALPSGV TH_1548|M.thermoresistible__bu -----------MADAEFTVTVGPLTARP----------DDTAPLTMPDGQ Mb1722|M.bovis_AF2122/97 -----------MADAEFTIGVTTELADH----------GDPVALALASGE Rv1696|M.tuberculosis_H37Rv -----------MADAEFTIGVTTELADH----------GDPVALALASGE MMAR_2501|M.marinum_M -----------MADAEFTIAVGVEVADE----------DDAAALTLPTGE MUL_1685|M.ulcerans_Agy99 -----------MADAEFTIVVGVEVADE----------DDAAALTLPTGE MAV_3075|M.avium_104 -----------MADAQFSIDVSTDVVPAG------SGSDDAAVLTLPSGE MLBr_01360|M.leprae_Br4923 -----------MVDAEFTISVTTDLIPL-------TDYKRSAAVTLPSGG MAB_2361|M.abscessus_ATCC_1997 -----------MDRAAFSIGVEPIAARP----------DDSAPLTLPSGQ MSMEG_3808|M.smegmatis_MC2_155 TLIVVEHDLDTIAHADWVVDIGPAAGEHGGQIVHSGTYDDLLRNPESLTG : * : : : . Mflv_3507|M.gilvum_PYR-GCK TVHAGRDGVDAVEFGFAAHGGSDLLPLNKSASGGELSRVMLALEVVLSAS Mvan_3288|M.vanbaalenii_PYR-1 TVHAGHDGVDAVEFGFAAHGGSDLLPLNKSASGGELSRVMLALEVVLSAS TH_1548|M.thermoresistible__bu TVHAGRHGVDGVEFGFTAHRGTDVLPLAKSASGGELSRVMLALEVVLAAS Mb1722|M.bovis_AF2122/97 LARAGADGVDAVEFGFVAHRGMTVLPLAKSASGGELSRVMLSLEVVLATS Rv1696|M.tuberculosis_H37Rv LARAGADGVDAVEFGFVAHRGMTVLPLAKSASGGELSRVMLSLEVVLATS MMAR_2501|M.marinum_M RVRAGGDGVDLVEFGFAAHRGMTVLPLAKSASGGELSRVMLALEVVLAAS MUL_1685|M.ulcerans_Agy99 RVRAGGDGVDLVEFGFAAHRGMTVLPLAKSASGGELSRVMLALEVVLAAS MAV_3075|M.avium_104 RVRAGADGIDQVEFGFAAHRGMDRLPLAKSASGGELSRVMLALEVVLAAS MLBr_01360|M.leprae_Br4923 VARAGADGVDQVEFGFAAHRGMTVLPLAKSASGGELSRVMLALEVVLATS MAB_2361|M.abscessus_ATCC_1997 TVHAGSSGTDVVEFGFAAHRDNPMLPLAKSASGGELSRVMLALEVVLAAS MSMEG_3808|M.smegmatis_MC2_155 AYLSGKESIEVPAIRRPVDKKRQITVVGARENNLKEIDVAFPLGVLTSVT :* . : : .. : .. : * :.* *: :.: Mflv_3507|M.gilvum_PYR-GCK ---TEGTTMVFDEVDAGVGG------------------------------ Mvan_3288|M.vanbaalenii_PYR-1 ---TEGTTMVFDEVDAGVGG------------------------------ TH_1548|M.thermoresistible__bu ---AEGTTMVFDEVDAGVGG------------------------------ Mb1722|M.bovis_AF2122/97 RKQAAGTTMVFDEIDAGVGG------------------------------ Rv1696|M.tuberculosis_H37Rv RKQAAGTTMVFDEIDAGVGG------------------------------ MMAR_2501|M.marinum_M ---AAGTTMVFDEVDAGVGG------------------------------ MUL_1685|M.ulcerans_Agy99 ---AAGTTMVFDEVDAGVGG------------------------------ MAV_3075|M.avium_104 RKETVGTTMVFDEVDAGVGG------------------------------ MLBr_01360|M.leprae_Br4923 ---AAGTTMVFDEVDVGVGG------------------------------ MAB_2361|M.abscessus_ATCC_1997 ---TAGTTMVFDEVDAGVGG------------------------------ MSMEG_3808|M.smegmatis_MC2_155 GVSGSGKSTMVNDILATVLANKLNGARLVPGRHTRVNGLDQLDKLVRVDQ *.: :.::: . * . Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_3808|M.smegmatis_MC2_155 SPIGRTPRSNPATYTGVFDKIRSLFAATTEAKVRGYQPGRFSFNVKGGRC Mflv_3507|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3288|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_1548|M.thermoresistible__bu -------------------------------------------------- Mb1722|M.bovis_AF2122/97 -------------------------------------------------- Rv1696|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2501|M.marinum_M -------------------------------------------------- MUL_1685|M.ulcerans_Agy99 -------------------------------------------------- MAV_3075|M.avium_104 -------------------------------------------------- MLBr_01360|M.leprae_Br4923 -------------------------------------------------- MAB_2361|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_3808|M.smegmatis_MC2_155 EACSGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKTISEVLD Mflv_3507|M.gilvum_PYR-GCK --------------------RAAVQIGRRLARLARTHQVIVVTHLPQVAA Mvan_3288|M.vanbaalenii_PYR-1 --------------------RAAVQIGRRLARLARTHQVIVVTHLPQVAA TH_1548|M.thermoresistible__bu --------------------RAAVQIGRRLARLARTHQVIVVTHLPQVAA Mb1722|M.bovis_AF2122/97 --------------------WAAVQIGRRLARLARTHQVIVVTHLPQVAA Rv1696|M.tuberculosis_H37Rv --------------------WAAVQIGRRLARLARTHQVIVVTHLPQVAA MMAR_2501|M.marinum_M --------------------WAAVQIGRRLARLARTHQVIVVTHLPQVAA MUL_1685|M.ulcerans_Agy99 --------------------WAAVQIGRRLARLARTHQVIVVTHLPQVAA MAV_3075|M.avium_104 --------------------RAAVQIGRRLARLARTHQVIVVTHLPQVAA MLBr_01360|M.leprae_Br4923 --------------------RAAVQIGRRLARLARTHQVIVVTHLPQVAA MAB_2361|M.abscessus_ATCC_1997 --------------------RAAVQIGRRLAKLAHTHQVIVVTHLPQVAA MSMEG_3808|M.smegmatis_MC2_155 MSIEEATEFFEPISSIHRYLKTLVDVGLGYVRLGQPAPTLSGGEAQRVKL : *::* .:*.:. .: . :* Mflv_3507|M.gilvum_PYR-GCK YADVHLVVEGVGNDGAGSGDG--------------KKARAKSSGVRRLDD Mvan_3288|M.vanbaalenii_PYR-1 YADVHLVVEGV----AGRDDG--------------RKARAKSSGVRRLDD TH_1548|M.thermoresistible__bu YADIHLVVDSG-----GRDAD--------------NRG---ASRVQRLDE Mb1722|M.bovis_AF2122/97 YADVHLMVQRTG--------------------------RDGASGVRRLTS Rv1696|M.tuberculosis_H37Rv YADVHLMVQRTG--------------------------RDGASGVRRLTS MMAR_2501|M.marinum_M YADVHLMVHGT---------------------------KGGASEVRRLSD MUL_1685|M.ulcerans_Agy99 YADVHLMVHGT---------------------------KGGASEVRRLSD MAV_3075|M.avium_104 YADVHLVVHGAG--------------------------PRGTSVVRRVTG MLBr_01360|M.leprae_Br4923 YADVHLVVHSAG--------------------------LDGASDVRRLAG MAB_2361|M.abscessus_ATCC_1997 FADIHLTVDRVN---------------------------SKGSGVRRLDD MSMEG_3808|M.smegmatis_MC2_155 AAELQKRSTGRTIYILDEPTTGLHFEDIRKLLKVINGLVDKGNTVIVIEH *::: . * : Mflv_3507|M.gilvum_PYR-GCK DDRVAELARMLAGLGE---SDSGRAHAR-------------------DLL Mvan_3288|M.vanbaalenii_PYR-1 DDRVAELARMLAGLGE---SDSGRAHAR-------------------ELL TH_1548|M.thermoresistible__bu EGRVAELARMLAGLGE---TDSGRAHAR-------------------ELL Mb1722|M.bovis_AF2122/97 EDRVAELARMLAGLGD---SDSGRAHAR-------------------ELL Rv1696|M.tuberculosis_H37Rv EDRVAELARMLAGLGD---SDSGRAHAR-------------------ELL MMAR_2501|M.marinum_M DERVGELARMLAGLGE---SDSGRAHAR-------------------ELL MUL_1685|M.ulcerans_Agy99 DERVGELARMLAGLGE---SDSGRAHAR-------------------ELL MAV_3075|M.avium_104 DERVAELARMLAGLGE---SDSGRAHAR-------------------ELL MLBr_01360|M.leprae_Br4923 DDRVAELARMLAGLGE---SDSGRAHAR-------------------ELL MAB_2361|M.abscessus_ATCC_1997 EDRVAELARMLAGLGD---SDTGRAHAR-------------------ELL MSMEG_3808|M.smegmatis_MC2_155 NLDVIKTSDWIIDMGPEGGAGGGTVVAQGTPEDVAANPDSYTGKFLAELL : * : : : .:* :. * . *: :** Mflv_3507|M.gilvum_PYR-GCK DAARKDRAAE---- Mvan_3288|M.vanbaalenii_PYR-1 DAARAERAAAD--- TH_1548|M.thermoresistible__bu EAAQRERAEVSV-- Mb1722|M.bovis_AF2122/97 ETAQNDELT----- Rv1696|M.tuberculosis_H37Rv ETAQNDELT----- MMAR_2501|M.marinum_M DTARNDKD------ MUL_1685|M.ulcerans_Agy99 DTARNDKD------ MAV_3075|M.avium_104 DAAQKDEI------ MLBr_01360|M.leprae_Br4923 DAARKDKS------ MAB_2361|M.abscessus_ATCC_1997 DAARAERT------ MSMEG_3808|M.smegmatis_MC2_155 DVPTPKRKRRKVSA :.. ..