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MSMHKLTAGDGYLYLVRQVAAADSTERGRSSLADYYSAKGESPGRWMGRGLAALADTGAREVSDEVRQNV WAVEGGSVVTEAQMKALFGLGWHPNADKIYGHLSPRLGVQPATAAGQLGRKYPAQEEPSSEFTRRVGKAF RAHNIEAGLAGNATIDDDVRAGIRTQVAREMFAEQFGRDPADDRELSGFVARATRARTTAVAGYDLTFSP VKSISALWAIAPPEIAEQIEAAHEAAVADVLEWLQDKAAFTRTGTNGVAQVDTEGLIAAVFTHRDSRAGD PDLHTHVAIANKVSYLDQNGVRRWLALDGQPLHRVIVAASEMYNTRMEVHTIDRLGVDFAEASRGRGKRP VREIVGMSVELMMRWSSRGIAIKARTAELAKQFQHDHGREPTTIESLALAQQATLESREAKHEPRSFAEQ RATWRNQAIEVLGHDGLNRMLATVLAPRRAQKTPEITAEWVASRAVALVATVAETRATWQAHHVRAEALR MVRAEGVAHVAGLVERLTDTALSEAFSVPHARVEDGELGEPVALRRRDGSSVYSRHGVATYTSRDVLAAE ERILAAVARRDGRMATASEVDLALSDSAARGKPLNLGQAALVEQMATSGRRVALALAPAGAGKTTAMAAL AHAWRSSGGHVLGLAPTAAAAIVLGEDLGATTDTLDKYVHCADPDNAATFGTPQWFTDIGPDTLIIVDEA GMASTAGLDAMIADAQRKGASVRLVADDCQLASISAGGVLRDIATETGALTLSEVVRFHSRAEAAASLAL RGGDPAGIGFYIDSGRIHVGTEQTAADTAFSAWLADRNAGRDSLLLGPTNAIVDDLNARARTARIAAHVE ADPNWRPGRETVLADQLRASVGDVIRTRHNARWLPLSGTDYVRNGYTFDILDVARDGALRARHSGTGHEI TLPADYVTEHVTLGYASTINGAQGSTAGYSCHVVGAEHLTRQQLYVALTRGRAENHLYLSTAETDPHRIL APKATHPDTAVDVLSRIVARGGGQVSATTTARQAADPTRRLAAAADMFTDALGAAAEHQLGAGARDRLDA IAESVHTDLSTCAAWPVLRRRLAVRALSGADPGELLAAAHARGGLDDAADAAAVLDYRIDPTGSAGRDCG PLRWLPAIPDRLAGDPQWGDYLRRRGQLVSDLADQIREQARAWTPDTAPSWAQPLVTANPALAAEIAVFR AATGVDGADTRLTGPAQYPVATRAIQDLLQRHGTDAIERNSADPTRFNDLLDQIDPRIRADAYWPTLAAH LTNAARGNDISDAITAAAQRGPLPDEMPAAALWWRLADALSRTAAIPDRTVVDHATAQGDGLHASIAAER ALVEVLAASWRNADPLPLARPRTDPAAVALSLPYVVATVAAERYTPELAEAIHTAATDANRHHVRITATP QPDRLSLNHLAEQITIHEPTRRGPVIVVEDAAAADPDALAAVATALVPAHGRLLLVDNGQLGSARRLLDG LTLPWAENTRPAAGIDNPRLAAAADEHRAIAARSWRTLTTGPTRDRGRDRDRGHGLDID
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3254 | - | - | 100% (1529) | exonuclease V subunit alpha |
| M. vanbaalenii PYR-1 | Mvan_3734 | - | 0.0 | 69.03% (1314) | exonuclease V subunit alpha |
| M. vanbaalenii PYR-1 | Mvan_1208 | - | 4e-09 | 26.38% (398) | exodeoxyribonuclease V, alpha subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2338 | - | 1e-10 | 38.95% (95) | hypothetical protein Mb2338 |
| M. gilvum PYR-GCK | Mflv_2792 | - | 0.0 | 69.18% (1314) | exonuclease V subunit alpha |
| M. tuberculosis H37Rv | Rv2311 | - | 1e-10 | 38.95% (95) | hypothetical protein Rv2311 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3605 | - | 2e-71 | 30.64% (878) | ATP-dependent exoDNAse (exonuclease V) |
| M. avium 104 | MAV_4544 | recD | 4e-11 | 27.36% (413) | exodeoxyribonuclease V, alpha subunit |
| M. smegmatis MC2 155 | MSMEG_3290 | - | 3e-05 | 32.35% (204) | regulatory protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_5087 | - | 5e-11 | 40.96% (83) | hypothetical protein MUL_5087 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3254|M.vanbaalenii_PYR-1 --MSMHKLTAGDGYLYLVRQVAAADSTERGRSSLADYYSAKGESPGRWMG
Mflv_2792|M.gilvum_PYR-GCK MVMTLHKLTAGDGYLYLVRQVAAADSTERGRSTLADYYSAKGESPGRWMG
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 ------------------------------------------MVQVSGVS
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 RGLAALADTGAREVSDEVRQNVWAVEGGSVVTEAQMKALFGLGWHPNADK
Mflv_2792|M.gilvum_PYR-GCK RGLAALSNTGRFEVSPTAREEIWTVEEGSGVSETQMRALYGVGLHPNAQR
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M -----------------------------------------MLTIAKLSR
MSMEG_3290|M.smegmatis_MC2_155 RDDGPVAGLIGRRDECAVLDQLVDAVAGGASRALMIRGEAGVGKTALLDY
MAV_4544|M.avium_104 -----------------------------------MLPERVFDAGPLRPF
Mvan_3254|M.vanbaalenii_PYR-1 IYGHLSPRLGVQPATAAGQLGRKYPAQEEPSSEFTRRVGKAFRAHNIEAG
Mflv_2792|M.gilvum_PYR-GCK IQTYVTGHN-MGNQRAASRLGREFQVRDG-KPEFSRRLAVAFRDHNAEIG
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M WSINYYNDTARAAGAAAADAQRAGGGLGEYYAEHDTRTPVWLCAGDAHTA
MSMEG_3290|M.smegmatis_MC2_155 AAARAAELQIARIVGIQSEMELAFAGIHQLCLPLLPRLGHLPVPQRDALE
MAV_4544|M.avium_104 ADAGIFEAADIHVAQRLTALTGESDDRVALAVALLVRALRGGSVCVDLRA
Mvan_3254|M.vanbaalenii_PYR-1 LAGNATIDDDVRAGIRTQVAREMFAEQFGRDPADDRELSGFVARATRART
Mflv_2792|M.gilvum_PYR-GCK AHWNATIGPEIRSGIRTRMAMELFGEEYGRPPADDRELSGFIARNTRAKT
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M AKLVGLTDVQRAGGPADPEVVQRWLDDGTAPNG---------ASGRAFGN
MSMEG_3290|M.smegmatis_MC2_155 VALGMATGSSPDRFLVGLAVLNLLADAAADRPLLCLVDDEQWLDRSSAQV
MAV_4544|M.avium_104 VPAQVGAADLPWPAAGDWLAAVRASPLLGPPPVLRFFGDLLYFDRYWLEE
Mvan_3254|M.vanbaalenii_PYR-1 TAVAGYDLTFSPVKSISALW--AIAP-PEIAEQIEAAHEAAVADVLEWLQ
Mflv_2792|M.gilvum_PYR-GCK TAVAGYDLTFSPVKSVSALW--AIAP-LPVAEQIEAAHDAAVADVLEWLQ
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M RGVHGFDLTFCAPKSVSLIR--ALRAGDVADKAIATAHATAVSEALEYLA
MSMEG_3290|M.smegmatis_MC2_155 LAFVARRLGSESVGMIFAAREPSDAAAGVPALVVRGLRGADARALLDSAL
MAV_4544|M.avium_104 EQVCTDLLALSAP-------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 DKAAFTRTG---TNGVAQVDTEGLIAAVFTHRDSRAGDPDLHTHVAIANK
Mflv_2792|M.gilvum_PYR-GCK EQAAFTRTG---AGGVAQVDTEGLIAAVFTHRDSRAGDPDLHTHVAISNK
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M AHAGYTRVHNPVTGEKDLLRLPGLVAIAYQHETSRAGDPHLHTHVIVPNR
MSMEG_3290|M.smegmatis_MC2_155 SAPLDPRVRDQILAETDGNPLALLELPRTLTRDALAGVFGLPGGSGVAAD
MAV_4544|M.avium_104 ------------AGDVESSCYERLFPPGYEEQRAAARIAVSQALTVLTGG
Mvan_3254|M.vanbaalenii_PYR-1 VSYLDQNGVRRWLALDGQPLHRVIVAASEMYNTRMEVHTIDRLGVDFAEA
Mflv_2792|M.gilvum_PYR-GCK VSYVDANGVRRWLALDGQPLHRVTVAASELYNTRLEAHLIARLGVRFAEQ
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M QARADGQLVS----IDGTSLYHEAKAAGVIYQATLRRELHQSLGFEWLPV
MSMEG_3290|M.smegmatis_MC2_155 IEHAFGVRIGELPEPTRDLLLIAAAEPTGDAPLVWRAAARLGIGSDAAAP
MAV_4544|M.avium_104 PGTGKTTTVARLLALLVEQAERAGEPRPRIALAAPTGKAAARLAEAVAAE
Mvan_3254|M.vanbaalenii_PYR-1 SRGRGKRPVREIVGMSVELMMRWSSRGIAIKARTAELAKQFQHDHGREPT
Mflv_2792|M.gilvum_PYR-GCK SRGRGKRPVREIVGMSARLMERWSSRRAAIKARTAELAKQFQADHGREPT
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M DPATGMAEVAGIAPESVTAWSQRSSQLREWAAGNLALADGQNLSPAQLS-
MSMEG_3290|M.smegmatis_MC2_155 AVEAELASFDTRVTFQHPLVRSVVYRAAALDDRRRAHRALAAATDAEVDP
MAV_4544|M.avium_104 IEHLDPADRARLAGLTGTTLHRLLGPRPDTSVRFKHNRG-----------
Mvan_3254|M.vanbaalenii_PYR-1 TIESLALAQQATLESREAKHEPRSFAEQRATWRNQAIEVLGHDGLNRMLA
Mflv_2792|M.gilvum_PYR-GCK NVEIIALAQHATLESREAKHEPRSLGEQRQEWRTQAVEVLGERGVNQMLS
MUL_5087|M.ulcerans_Agy99 -----------------------------------------------MLA
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M ---------AAQKATRPAKPEQLSFAELRAAWR--------ADERGVRLD
MSMEG_3290|M.smegmatis_MC2_155 DRRAWHLAHAAAGPDAAAAAELESSAARARSRGGACAAAAFLERATALTV
MAV_4544|M.avium_104 ---------------------------------------------NRLPH
Mvan_3254|M.vanbaalenii_PYR-1 TVLAP-RRAQKTPEITAEWVASRAVALVATVAETRATWQAHHVRAEALRM
Mflv_2792|M.gilvum_PYR-GCK DTLAAPQTTREAVTIDEEWFASRAGELIATVAESRSTWQRHHVRAEALRM
MUL_5087|M.ulcerans_Agy99 DTLTA--RERPGVEITPDWIQSQAAAVIETISKSRSAWERNHVFAEAQRS
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M DAARRAARQARREGSRQPFDRRRLAAAAEQIDKAGFTRADLVEIVGAQLP
MSMEG_3290|M.smegmatis_MC2_155 DPVLRNDRALAAAAAKAEAGAFESAQDLLAMVEATSLSDLQQAQVDVLRA
MAV_4544|M.avium_104 DIIVVDETSMVSLTMMARLAEAVRPDTRLILVGDPDQLASVEAGAVLADL
Mvan_3254|M.vanbaalenii_PYR-1 VRAEGVAHVAGLVERLTDTALSEAFSVPHARVEDG------------ELG
Mflv_2792|M.gilvum_PYR-GCK ARGHDVAHDVALVERLTDTALGEGFSVPHARVEDA------------ELG
MUL_5087|M.ulcerans_Agy99 ARTEGAALDPRVAVAITDTALQEPQSIPRPRS------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M VDTEQSPRRLVEAAVEEIGILLTAARQPHQREGHDRFTLDRILAEEAALL
MSMEG_3290|M.smegmatis_MC2_155 RLAFVTSHGSDAPPLLLKAARRLGGIDPDRARAVY---------------
MAV_4544|M.avium_104 VDGLAGRAGVRVAALATPHRFGSAIG------------------------
Mvan_3254|M.vanbaalenii_PYR-1 EPVALRRRDGSSVYSRHGVATYTSRDVLAAEERILAAVARRDGRMATASE
Mflv_2792|M.gilvum_PYR-GCK EPVALRRRDGASVYRRHGVALYTSQETLAAEQRILDAVHRGDGRVASAAD
MUL_5087|M.ulcerans_Agy99 ---AHKSR------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M QL-------------------------------------------VDAQD
MSMEG_3290|M.smegmatis_MC2_155 ----------------------------------------LDAMLAAMFA
MAV_4544|M.avium_104 ---------------------------------------------ALAAA
Mvan_3254|M.vanbaalenii_PYR-1 VDLALSDSAARGKPLNLGQAALVEQMATSGRRVALALAPAGAGKTTAMAA
Mflv_2792|M.gilvum_PYR-GCK VEMALADSTARGRTLNPGQAALVTEMATAGRRVALALAPAGTGKTTAMAA
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M IRAELWVKERDTEGLSPDQKRVVENIATSPWLVQPLSAPAGAGKTTSLRA
MSMEG_3290|M.smegmatis_MC2_155 GRLATGANLVEVAAAARSAPERSGAAEVSDLLLDWLTAHYGRGYVAARSA
MAV_4544|M.avium_104 IRAGDADRVVELLAAGGEHIEWVDSERPADRLREVLVSHALRLRSAALLG
Mvan_3254|M.vanbaalenii_PYR-1 LAHAWRS-SGGHVLGLAPT-AAAAIVLGEDLGATTDTLDKYVHCADPDNA
Mflv_2792|M.gilvum_PYR-GCK LAHAWRS-SGGHVIGLAPT-ADAAIVLGEDLGATTDTLDKYVWSADPAKA
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 ---------------MAPTGQAVDVAVREGAGDVGYSVE-----------
Rv2311|M.tuberculosis_H37Rv ---------------MAPTGQAVDVAVREGAGDVGYSVE-----------
MMAR_3605|M.marinum_M LATMARRRHTARVFVLAPTGTAVDVAIREGAGDVGYTIAKALHELDKGTL
MSMEG_3290|M.smegmatis_MC2_155 LGDVLSAFDGEADDLPLNRMLLASTAAHYAWDDVRLDVFTAHHVERARAT
MAV_4544|M.avium_104 AAQAALATLDEHRLLCAHRDGPHGAVRWNTLVHN----------------
Mvan_3254|M.vanbaalenii_PYR-1 ATFGTPQWFTDIGPDTLIIVDEAGMASTAGLDAMIADAQRKGASVRLVAD
Mflv_2792|M.gilvum_PYR-GCK ATSHVPDWFSRVGPDTLIVVDEAGKAATAGLDAMIRDALKKGASVRLVGD
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M TLGHL----------DLVVVDEAAMVGTDDLRRLLAATTTARTKTVLVGD
MSMEG_3290|M.smegmatis_MC2_155 G-------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 DCQLASISAGG--VLRDIATETGALTLSEVVRFHSRAEAAASLALRGGDP
Mflv_2792|M.gilvum_PYR-GCK DGQLSSISAGG--ILRDIAEATDALTLSEVVRFKSPAEAAAGLALHDADP
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M AHQLAPVKARGGMFAQLCADLPWAQQLSEVWRMRDPEERTASLALRDGGP
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 AGIG----FYIDSGRIHVGTEQTAADTAFSAWLADRNAGRDSLLLGPTNA
Mflv_2792|M.gilvum_PYR-GCK AGIG----FYIDHHRIHVGTDETAADMAYQAWRADLAAGGDSILLAPTND
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M APVRRAVEWYRTHDRLHTGDAITMAADALAAYNRDTAAGRNALLICDTTE
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 IVDDLNARARTARIAAHVEADPNWRPGRETVLADQLRASVGDVIRTRHNA
Mflv_2792|M.gilvum_PYR-GCK VINELNARARIDRLAADPEAAK----SPTVVLAEQLHASVGDTIRTRKNN
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 ----------RENLPAD---------------------------------
Rv2311|M.tuberculosis_H37Rv ----------RENLPAD---------------------------------
MMAR_3605|M.marinum_M MADALNRRIHRDIIAADQPAVIAARGHRIAVGDLIISRRNDPTLPVFDAT
MSMEG_3290|M.smegmatis_MC2_155 -------ALSEVPIALNSRAIALLFFGDLDGAADAVDEIQAADDATGALL
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 RWLPLSGTDYVRNGYTFDILDVARDG-ALRARHSGTGHEITLPADYVTEH
Mflv_2792|M.gilvum_PYR-GCK RRIGIGRNDFVRNGYRYTITEVLADG-GVKARHLRSGRIVTLPADYIAEH
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------DPVRNGNRWRVIAVDTEHHRIAARRLGDGARAAFSGDYLHEH
Rv2311|M.tuberculosis_H37Rv --------DPVRNGNRWRVIAVDTEHHRIAARRLGDGARAAFSGDYLHEH
MMAR_3605|M.marinum_M DIK--KGADPVRNGNRWRIYAVDPGNNRVAARRLHDGARAAFTGDYLREH
MSMEG_3290|M.smegmatis_MC2_155 APYAEVGLAAMRGDLARTASLVDATVAAVTARGEGNGLTVAWWAEAVLHN
MAV_4544|M.avium_104 ---------WIAEETGQPAWSQWYAGRPLLVTANDYGLRLYNGDTGVTVA
Mvan_3254|M.vanbaalenii_PYR-1 VTLGYASTINGAQGSTAG-----YSCHVVGAEHLTRQQLYVALTRGRAEN
Mflv_2792|M.gilvum_PYR-GCK VTLGYAATIDSAQGLTSGSRDTRGTCHIVGSDMLTRQHLYVALTRGTDEN
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 ITHGYAITVHASQGTTAH------STHAVLGDNTSRATLYVAMTPARESN
Rv2311|M.tuberculosis_H37Rv ITHGYAITVHASQGTTAH------STHAVLGDNTSRATLYVAMTPARESN
MMAR_3605|M.marinum_M ITYGYAITVHSAQGVTAD------TTHAVLGENTTRALLYVAMTRGRSAN
MSMEG_3290|M.smegmatis_MC2_155 GFGSARKALEAASRAAAFPPELASANWALIELVEAATRCGAVETAAEAAA
MAV_4544|M.avium_104 GADGLRAVIAGAAGPLDF-------ATSRLGEVETMHAMTIHKSQGSQAD
Mvan_3254|M.vanbaalenii_PYR-1 HLYLSTAETDPHRILAPKATHPDTAVDVLSRIVARGGGQVSATTTARQAA
Mflv_2792|M.gilvum_PYR-GCK HLYLSTAEGDPHRLLSPKATHPDTAVDVLTRILARNGAQVSATTAARQAA
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 TAYLCERTAGEG-------------------------------ARVDLAG
Rv2311|M.tuberculosis_H37Rv TAYLCERTAGEG-------------------------------ARVDLAG
MMAR_3605|M.marinum_M TAYLHERIAGENEHRQPNGVH---------IPRRGTAKEAAQRARTIIAN
MSMEG_3290|M.smegmatis_MC2_155 DLAELTTSSGTDWALG-----------------LAARARALVSGPAESER
MAV_4544|M.avium_104 EVTVLIPPEDSR-----------------------------LLTRELFYT
Mvan_3254|M.vanbaalenii_PYR-1 DPTRRLAAAADMFTDALGAAAEHQLGAGARDRLDAIAESVHTDLSTCAAW
Mflv_2792|M.gilvum_PYR-GCK DPAARLQAAADMYYDALGAAAENRLGVGARDRLDAIADEVIPQLSQREAW
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 WDLWVSGKAEAMSDEKSASPVWCRVGARCDHRG---KRSCW---------
Rv2311|M.tuberculosis_H37Rv WDLWVSGKAEAMSDEKSASPVWCRVGARCDHRG---KRSCW---------
MMAR_3605|M.marinum_M QDEQAR-TADQIAQDADASALPERVRSLLRRRSDAIRQRCTTYQQWRNAV
MSMEG_3290|M.smegmatis_MC2_155 WYLESIERLENTRARAELARSRLVYGEWLRRERRRTAARSELRTAHEMFS
MAV_4544|M.avium_104 AVTRAKSRVRVVGPEASVRAAIERRAIRATGLRQRLRVVG----------
Mvan_3254|M.vanbaalenii_PYR-1 PVLRRRLAVRALSGADPGELLAAAHARGGLDDAADAAAVLDYRIDPTGSA
Mflv_2792|M.gilvum_PYR-GCK PVLRRNLSVLALRGADPRELLTEALAKGSVSDAADPAAVLDHRIDPAGTH
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M AGMNITDGYTLGQHIDRSRGQYVGYQAGL---------------------
MSMEG_3290|M.smegmatis_MC2_155 AMGMSAFAARAQRELAAAGDRIRETVIAAVDHRLTAQEAHIARLARDGLS
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 GRDCGPLRWLPAIPDRLAGDPQWGDYLRRRGQLVSDLADQIREQARAWTP
Mflv_2792|M.gilvum_PYR-GCK SSGIGVLRWLPAVPEALAEDPQWGAYLARREKLVEDLAGEIRERARGWTN
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 NPEIGARLFISARTVQYHLGKVFTKLGITSRSQLDGVLGHVTDR------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 DTAPSWAQPLVTANPALAAEIAVFRAATGVDGADTRLTGPAQYPVATRAI
Mflv_2792|M.gilvum_PYR-GCK ATAPAWARPLITVNPVLTAESAVFRAATGVAEADTRITGARQFPVRSRGV
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 QDLLQRHGTDAIERNSADPTRFNDLLDQIDPRIRADAYWPTLAAHLTNAA
Mflv_2792|M.gilvum_PYR-GCK QAALQRQAAADIGRHSADTSRWNDVIDGIDPRLRSDAYWPQLADQLVKAA
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 RGN-DISDAITAAAQRGPLPDEMPAAALWWRLADALSRTAAIPDRT----
Mflv_2792|M.gilvum_PYR-GCK RITPQLRQIITTAARQGPLPDELPAAALWWRISGALSPTATLATTHSRLR
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 ---VVDHATAQGDGLHASIAAERALVEVLAAS-------WRNADPLPLAR
Mflv_2792|M.gilvum_PYR-GCK PPWVTDIDVVFGTSLAETITSDPAWPGLVAAIGAADPRKWTPRDLLHVAA
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 PR------------------------------------------------
Mflv_2792|M.gilvum_PYR-GCK EQLADATDGDHPIPPGDYARLITYTVDAFTHRLQARLGVDFQDLPAPEDT
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 -TDPAAVALSLP--------------------------------------
Mflv_2792|M.gilvum_PYR-GCK PIDPAEEALFPPDPQDPSAHVEEHSPFDDSVDLAPPEEIDSFEYGSEGYA
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 -YVVATVAAERYTPEL-----------------AEAIHTAATDANR----
Mflv_2792|M.gilvum_PYR-GCK GLRFEDLSANRPTPELGITMDAFIALRAEYRNVCDEIKTLAADIRAGNGP
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 -----------------------------------------------HHV
Mflv_2792|M.gilvum_PYR-GCK ALRAAAGDLLRMRHQVDADRPYSHAITDVMEQWSDADRAYNDTLRLIEHS
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 R-----ITATPQPDRLSLNHLAEQITIH----------------------
Mflv_2792|M.gilvum_PYR-GCK RSQLDLLLATPDAEELDIISARQQIAFYTDMLPEQPPSLQFQQALADAQA
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2792|M.gilvum_PYR-GCK ARAAAAGGGGGGDKIVTERDIAAARGAAERTDIAALNVLRVRRPVLRREL
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 ------------------------------------------EPTRR---
Mflv_2792|M.gilvum_PYR-GCK ERAERDIATAFAAAQTSTSDTLEQLLESARSEVALLRVSGHLDPERTPLR
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2792|M.gilvum_PYR-GCK IPDAALSGLEPQTADRLKSVAAQPYRLAVIRADITDSETAAALYTLRNAA
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 ------------------------------------------------GP
Mflv_2792|M.gilvum_PYR-GCK NAEDRKVLWLSPTEASLTPAHDAELADTITTIRHAHQQVSEQQWALSAGA
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 VIVVEDAAAADPDALAAVATALVPAHGRLLLVDN----GQLGSARRLLDG
Mflv_2792|M.gilvum_PYR-GCK IVVIEDPAAAEPDQLVGLARHAADADARLVLLDPGTSRGPSSSAVQLLTN
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 -LTLPWAENTRPAAGID----NPRLAAAAD---------------EHRAI
Mflv_2792|M.gilvum_PYR-GCK SLPWNNALTTTPSTPEDPLLASTPAVTLADRLGRKRLSEPWQQLLTHYDI
MUL_5087|M.ulcerans_Agy99 --------------------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3605|M.marinum_M --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4544|M.avium_104 --------------------------------------------------
Mvan_3254|M.vanbaalenii_PYR-1 AARSWRTLTTG------PTRDRG--RDRDRGHGLDID-
Mflv_2792|M.gilvum_PYR-GCK AARAIRSAQRRQLARGWHTTDLAPSKDRDRTLGAGIDD
MUL_5087|M.ulcerans_Agy99 --------------------------------------
Mb2338|M.bovis_AF2122/97 --------------------------------------
Rv2311|M.tuberculosis_H37Rv --------------------------------------
MMAR_3605|M.marinum_M --------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------------------------
MAV_4544|M.avium_104 --------------------------------------