For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VLPERVFDAGPLRPFADAGIFEAADIHVAQRLTALTGESDDRVALAVALLVRALRGGSVCVDLRAVPAQV GAADLPWPAAGDWLAAVRASPLLGPPPVLRFFGDLLYFDRYWLEEEQVCTDLLALSAPAGDVESSCYERL FPPGYEEQRAAARIAVSQALTVLTGGPGTGKTTTVARLLALLVEQAERAGEPRPRIALAAPTGKAAARLA EAVAAEIEHLDPADRARLAGLTGTTLHRLLGPRPDTSVRFKHNRGNRLPHDIIVVDETSMVSLTMMARLA EAVRPDTRLILVGDPDQLASVEAGAVLADLVDGLAGRAGVRVAALATPHRFGSAIGALAAAIRAGDADRV VELLAAGGEHIEWVDSERPADRLREVLVSHALRLRSAALLGAAQAALATLDEHRLLCAHRDGPHGAVRWN TLVHNWIAEETGQPAWSQWYAGRPLLVTANDYGLRLYNGDTGVTVAGADGLRAVIAGAAGPLDFATSRLG EVETMHAMTIHKSQGSQADEVTVLIPPEDSRLLTRELFYTAVTRAKSRVRVVGPEASVRAAIERRAIRAT GLRQRLRVVG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_4544 | recD | - | 100% (570) | exodeoxyribonuclease V, alpha subunit |
M. avium 104 | MAV_1388 | - | 3e-06 | 27.31% (216) | ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0645c | recD | 0.0 | 71.40% (563) | exonuclease V alpha chain |
M. gilvum PYR-GCK | Mflv_5131 | - | 0.0 | 69.15% (551) | exodeoxyribonuclease V, alpha subunit |
M. tuberculosis H37Rv | Rv0629c | recD | 0.0 | 71.58% (563) | exonuclease V alpha chain |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0398c | - | 0.0 | 74.55% (550) | exodeoxyribonuclease V, alpha subunit (RecD) |
M. marinum M | MMAR_0956 | recD | 0.0 | 70.30% (569) | exodeoxyribonuclease V (alpha chain), RecD |
M. smegmatis MC2 155 | MSMEG_1325 | recD | 0.0 | 72.89% (557) | exodeoxyribonuclease V, alpha subunit |
M. thermoresistible (build 8) | TH_3422 | - | 2e-05 | 25.93% (162) | PUTATIVE conserved hypothetical protein |
M. ulcerans Agy99 | MUL_0707 | recD | 0.0 | 70.30% (569) | exodeoxyribonuclease V (alpha chain), RecD |
M. vanbaalenii PYR-1 | Mvan_1208 | - | 0.0 | 70.80% (548) | exodeoxyribonuclease V, alpha subunit |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_5131|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1208|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0645c|M.bovis_AF2122/97 -------------------------------------------------- Rv0629c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_4544|M.avium_104 -------------------------------------------------- MMAR_0956|M.marinum_M -------------------------------------------------- MUL_0707|M.ulcerans_Agy99 -------------------------------------------------- MAB_0398c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_1325|M.smegmatis_MC2_155 -------------------------------------------------- TH_3422|M.thermoresistible__bu VTTTVTERLLTPSKVTAWLDCPHYLSLCAQVDDGILPRPESRFGSFAELL Mflv_5131|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1208|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0645c|M.bovis_AF2122/97 -------------------------------------------------- Rv0629c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_4544|M.avium_104 -------------------------------------------------- MMAR_0956|M.marinum_M -------------------------------------------------- MUL_0707|M.ulcerans_Agy99 -------------------------------------------------- MAB_0398c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_1325|M.smegmatis_MC2_155 -------------------------------------------------- TH_3422|M.thermoresistible__bu LDKGRAHEQACLADFERQGKRVLRIPDRENGESFAAWVARVGNPLTDDHD Mflv_5131|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1208|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0645c|M.bovis_AF2122/97 -------------------------------------------------- Rv0629c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_4544|M.avium_104 -------------------------------------------------- MMAR_0956|M.marinum_M -------------------------------------------------- MUL_0707|M.ulcerans_Agy99 -------------------------------------------------- MAB_0398c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_1325|M.smegmatis_MC2_155 -------------------------------------------------- TH_3422|M.thermoresistible__bu VIYQMPFVHNGIAGIADFLVRVTHPDTGEVSWEPVDAKLTRIEAKPGHVL Mflv_5131|M.gilvum_PYR-GCK --------------------------MSLDAF------------------ Mvan_1208|M.vanbaalenii_PYR-1 --------------------------MTVEAF------------------ Mb0645c|M.bovis_AF2122/97 -------------MKLTDVDFAVEASGMVRAFNQ---------------- Rv0629c|M.tuberculosis_H37Rv -------------MKLTDVDFAVEASGMVRAFNQ---------------- MAV_4544|M.avium_104 --------------MLPER---VFDAGPLRPFAD---------------- MMAR_0956|M.marinum_M --------MTIDVVDPADWRQAASASGPLRTFNE---------------- MUL_0707|M.ulcerans_Agy99 --------MTIEVVDPADWRQAASASGPLRTFNE---------------- MAB_0398c|M.abscessus_ATCC_199 -------------------------MSLVEAF------------------ MSMEG_1325|M.smegmatis_MC2_155 -------------------------MSLLEAF------------------ TH_3422|M.thermoresistible__bu QLCFYADALEALTGRRPEHMHIWLGSGQLETLRVNEFQPYWRRLQTQLAA : .: Mflv_5131|M.gilvum_PYR-GCK ----------------------------------AEVFEPADIHVAQR-- Mvan_1208|M.vanbaalenii_PYR-1 ----------------------------------SELFEPADLHVAQR-- Mb0645c|M.bovis_AF2122/97 ----------------------------------AGVLDVSDVHVAQR-- Rv0629c|M.tuberculosis_H37Rv ----------------------------------AGVLDVSDVHVAQR-- MAV_4544|M.avium_104 ----------------------------------AGIFEAADIHVAQR-- MMAR_0956|M.marinum_M ----------------------------------AGVIDAADVHVAQR-- MUL_0707|M.ulcerans_Agy99 ----------------------------------ARVIDAADVHVAQR-- MAB_0398c|M.abscessus_ATCC_199 ----------------------------------GEILEPADVHVAQR-- MSMEG_1325|M.smegmatis_MC2_155 ----------------------------------AEILEPADVHVAQR-- TH_3422|M.thermoresistible__bu ALAAGPEAGTVAEQCAHCEFCEFQPTCEMYWRDTDSLIYVANIRKPDREA :: :::: .:* Mflv_5131|M.gilvum_PYR-GCK --------LTELGRDSDPTVALAVALAVRAVRSGSVCVDLRTVAAQVGVP Mvan_1208|M.vanbaalenii_PYR-1 --------LTTLGKEGDDSVALAVALAVRALRGGSVCVDLRAIATQVGMP Mb0645c|M.bovis_AF2122/97 --------LCALAGESDERVALAVAVAVRALRAGSVCVDLLSIARVAGHD Rv0629c|M.tuberculosis_H37Rv --------LCALAGESDERVALAVAVAVRALRAGSVCVDLLSIARVAGHD MAV_4544|M.avium_104 --------LTALTGESDDRVALAVALLVRALRGGSVCVDLRAVPAQVGAA MMAR_0956|M.marinum_M --------LAAMSGESDPVVLLAIAFVVRALRGGSVCVDLSTIEAQVGIA MUL_0707|M.ulcerans_Agy99 --------LAAMSGESDPVVLLAIAFVVRALRGGSVCVDLSTIEAQVGIA MAB_0398c|M.abscessus_ATCC_199 --------LTALASETDESVELAIALAVRALRGGSVCVDLRAVAAQVDMP MSMEG_1325|M.smegmatis_MC2_155 --------LTVLADEPDASVELAVALAVRALRGGSVCVDLRSVAGQVELP TH_3422|M.thermoresistible__bu LAGADIATLTALATSDGPVEGMDPDRLARLRRQAALQLAAREQQREKPPF * : . . : .* * .:: : Mflv_5131|M.gilvum_PYR-GCK ELPWPDPDGWLSTVGASP-LAEHK-VVRLDGD-LLYLDR----------- Mvan_1208|M.vanbaalenii_PYR-1 ELPWPEPDRWLAAVGASP-LADER-VLRMHGD-LLYLDR----------- Mb0645c|M.bovis_AF2122/97 DLPWPDPADWLAAVRASP-LLADPPVLHLYDDRLLYLDR----------- Rv0629c|M.tuberculosis_H37Rv DLPWPDPADWLAAVRASP-LLADPPVLHLYDDRLLYLDR----------- MAV_4544|M.avium_104 DLPWPAAGDWLAAVRASP-LLGPPPVLRFFGD-LLYFDR----------- MMAR_0956|M.marinum_M DLPWPAAGEWLAAVRASP-LVGSPAVLRLHEDNLVYLDR----------- MUL_0707|M.ulcerans_Agy99 DLPWPAAGEWLAAVRASP-LVGSPAVLRLHEDNLVYLDR----------- MAB_0398c|M.abscessus_ATCC_199 SLPWPAADDWLAAVRASP-LAGEPPVLRLFGD-LLYLDR----------- MSMEG_1325|M.smegmatis_MC2_155 DLPWPDPDAWLAALAASP-LLGQPPVLRLFGD-LLYLDR----------- TH_3422|M.thermoresistible__bu ELIRPGPEPWGHGFEMLPEPDGGDVFLDFEGHPFWRADTGLFFLFGLIEQ .* * . * . * .: : . : * Mflv_5131|M.gilvum_PYR-GCK -----------YWREEEQVRDDVVALLSS--PPRTAVPGLERLFPAGWEE Mvan_1208|M.vanbaalenii_PYR-1 -----------YWREEQQVCDDVLALLAS--PLPATAPSIERLFPAGWEE Mb0645c|M.bovis_AF2122/97 -----------YWREEEQVCADLLALLTS--RRPAGVPDLRRLFPTGFDE Rv0629c|M.tuberculosis_H37Rv -----------YWREEEQVCADLLALLTS--RRPAGVPDLRRLFPTGFDE MAV_4544|M.avium_104 -----------YWLEEEQVCTDLLALSAP--AGDVESSCYERLFPPGYEE MMAR_0956|M.marinum_M -----------YWREEQQVADDILALLAARASASGPAIEVNRLFPPGYEE MUL_0707|M.ulcerans_Agy99 -----------YWREEQQVADDILALLAARASASGPAIEVNRLFPPGYEE MAB_0398c|M.abscessus_ATCC_199 -----------YWREEQQVCTDVQALMAA-AQPRTEVPTYERLFPQGFEE MSMEG_1325|M.smegmatis_MC2_155 -----------YWLEEQQVCDDVLALVS--ARPGGAVPDVSRLFGAGFEE TH_3422|M.thermoresistible__bu DDDGGRWRYRCWWAHDRDEEAAAVAQLVEYLVERRKQHPAMHVYHYNHTE :* .:.: * ::: . * Mflv_5131|M.gilvum_PYR-GCK QRAAAEAALTRSLTVLTGGP------------------------------ Mvan_1208|M.vanbaalenii_PYR-1 QREAAKVALRQSLTVLTGGP------------------------------ Mb0645c|M.bovis_AF2122/97 QRRAAEIALSQGVTVLTGGP------------------------------ Rv0629c|M.tuberculosis_H37Rv QRRAAEIALSQGVTVLTGGP------------------------------ MAV_4544|M.avium_104 QRAAARIAVSQALTVLTGGP------------------------------ MMAR_0956|M.marinum_M QRAAAKIALAQGLTVLTGGP------------------------------ MUL_0707|M.ulcerans_Agy99 QRAAAKIALAQGLTVLTGGP------------------------------ MAB_0398c|M.abscessus_ATCC_199 QRAAADIALSQGLTVLTGGP------------------------------ MSMEG_1325|M.smegmatis_MC2_155 QRAAAKVALSQGLTVLTGGP------------------------------ TH_3422|M.thermoresistible__bu RSALQRMAEEHGVAELALAELIDTGAFVDLLLVARNSIQVGAESYGLKHL : * :.:: *: . Mflv_5131|M.gilvum_PYR-GCK --------------------------GTGKTTTVARLLAAFAEQAELAGG Mvan_1208|M.vanbaalenii_PYR-1 --------------------------GTGKTTTVARLLASIAEQAESAGG Mb0645c|M.bovis_AF2122/97 --------------------------GTGKTTTVARLLALVAEQAELAGE Rv0629c|M.tuberculosis_H37Rv --------------------------GTGKTTTVARLLALVAEQAELAGE MAV_4544|M.avium_104 --------------------------GTGKTTTVARLLALLVEQAERAGE MMAR_0956|M.marinum_M --------------------------GTGKTTTVARLLALFAEQAQLAGK MUL_0707|M.ulcerans_Agy99 --------------------------GTGKTTTVARLLALFAEQAQLAGK MAB_0398c|M.abscessus_ATCC_199 --------------------------GTGKTTTVARLLALLADQASSASA MSMEG_1325|M.smegmatis_MC2_155 --------------------------GTGKTTTVARLLALLAEQAALAGK TH_3422|M.thermoresistible__bu ERLTDFERSHDIDQGAGAVVQYEQYIADGNQAHLDAIAAYNADDVRATLA . *: : : : * .::. : Mflv_5131|M.gilvum_PYR-GCK PPPRMALAAPTGKAAARLQDAVQAEVDRLSAVDR---------------- Mvan_1208|M.vanbaalenii_PYR-1 APPRMALAAPTGKAAARLQDAVHAEVGKLPAVDQ---------------- Mb0645c|M.bovis_AF2122/97 PRPRIALAAPTGKAAARLAEAVRREMAKLDATDR---------------- Rv0629c|M.tuberculosis_H37Rv PRPRIALAAPTGKAAARLAEAVRREMAKLDATDR---------------- MAV_4544|M.avium_104 PRPRIALAAPTGKAAARLAEAVAAEIEHLDPADR---------------- MMAR_0956|M.marinum_M ARLRIALAAPTGKAAARLHEAVQSQIDKLDAIDQ---------------- MUL_0707|M.ulcerans_Agy99 ARLRIALAAPTGKAAARLHEAVQSQIDKLDAIDQ---------------- MAB_0398c|M.abscessus_ATCC_199 APLRIALAAPTGKAAARLQEAVQLEVNQLDAVDR---------------- MSMEG_1325|M.smegmatis_MC2_155 PSPRIALAAPTGKAAARLQEAVQLEIDQLDLIER---------------- TH_3422|M.thermoresistible__bu LRDWLVEHRPPGLPWRSAVLEPDPELPGLGETVERLHQFPVGSDEHNLGD :. *.* . :: * . Mflv_5131|M.gilvum_PYR-GCK -------------------------------ARLAGLRATTMHRLLG--S Mvan_1208|M.vanbaalenii_PYR-1 -------------------------------GRLAGLRATTLHRLLG--S Mb0645c|M.bovis_AF2122/97 -------------------------------ARLGDLHAVTLHRLLG--A Rv0629c|M.tuberculosis_H37Rv -------------------------------ARLGDLHAVTLHRLLG--A MAV_4544|M.avium_104 -------------------------------ARLAGLTGTTLHRLLG--P MMAR_0956|M.marinum_M -------------------------------QRVRGLQATTLHRLLG--S MUL_0707|M.ulcerans_Agy99 -------------------------------QRVRGLQATTLHRLLG--S MAB_0398c|M.abscessus_ATCC_199 -------------------------------SRLAGLQATTLHRLLG--S MSMEG_1325|M.smegmatis_MC2_155 -------------------------------RRLTGLHATTLHRLLG--P TH_3422|M.thermoresistible__bu LLNYWRDEGLAYIAPKNAKLATDPVDLYDDAEVIADLRPETLLESTGRAR : .* *: . * Mflv_5131|M.gilvum_PYR-GCK RPDTSSRFRHHRGNRLPHD---VIVVDET------SMVSLTMMARLLEAV Mvan_1208|M.vanbaalenii_PYR-1 RPDTSSRFRHHRDNRLPHD---VIVVDET------SMVSLTMMARLLEAV Mb0645c|M.bovis_AF2122/97 KP--GARFRQDRQNRLPHN---VIVVDET------SMVSLTLMARLAEAV Rv0629c|M.tuberculosis_H37Rv KP--GARFRQDRQNRLPHN---VIVVDET------SMVSLTLMARLAEAV MAV_4544|M.avium_104 RPDTSVRFKHNRGNRLPHD---IIVVDET------SMVSLTMMARLAEAV MMAR_0956|M.marinum_M RPDTSSRFRHHRGNRLPHD---VIVIDET------SMVSLTMMARLLEAV MUL_0707|M.ulcerans_Agy99 RPDTSSRFRHHRGNRLPHD---VIVIDET------SMVSLTMMARLLEAV MAB_0398c|M.abscessus_ATCC_199 RPDTSSRFKHDRGNRLPHD---VIVVDET------SMVSLTMMARLLEAV MSMEG_1325|M.smegmatis_MC2_155 RPDTSSRFRHHRANRLPHD---VIVVDET------SMVSLTMMARLLEAV TH_3422|M.thermoresistible__bu HPRRRFRFPDQDVDRFPSDGGSVMVATSTGERLCTGIANLDRDAHTLDLV :* ** .. :*:* : ::* .* .:..* *: : * Mflv_5131|M.gilvum_PYR-GCK R----------PDTRLLFVGDPDQLASVDAGAVLADLVDG---------- Mvan_1208|M.vanbaalenii_PYR-1 R----------PDTRLLFVGDPDQLASVDAGAVLADLVEG---------- Mb0645c|M.bovis_AF2122/97 R----------PGARLILVGDADQLASVEAGAVLADLVDG---------- Rv0629c|M.tuberculosis_H37Rv R----------PGARLILVGDADQLASVEAGAVLADLVDG---------- MAV_4544|M.avium_104 R----------PDTRLILVGDPDQLASVEAGAVLADLVDG---------- MMAR_0956|M.marinum_M R----------PQTRLLLVGDPDQLASVEAGAVLADLVDG---------- MUL_0707|M.ulcerans_Agy99 R----------PQTRLLLVGDPDQLASVEAGAVLADLVDG---------- MAB_0398c|M.abscessus_ATCC_199 R----------PQARLLLVGDPDQLASVEAGAVLADLVEG---------- MSMEG_1325|M.smegmatis_MC2_155 R----------PQTRLVLVGDPDQLASVEAGAVLADLVEG---------- TH_3422|M.thermoresistible__bu WNDKLQEAGCPPRIAVLHDWVKSEVKVKALQAFAEDLLDGRNPNPVTLAL * :: .:: *. **::* Mflv_5131|M.gilvum_PYR-GCK --------LGEAG---VVELTTSHRFGERIGALALAIRS--------GDA Mvan_1208|M.vanbaalenii_PYR-1 --------LGDAG---VVELKTPHRFGETIGSLAEAIRA--------GDA Mb0645c|M.bovis_AF2122/97 --------FSVRDDALVAQLRTSHRFGKVIGTLAEAIRA--------GDG Rv0629c|M.tuberculosis_H37Rv --------FSVRDDALVAQLRTSHRFGKVIGTLAEAIRA--------GDG MAV_4544|M.avium_104 --------LAGRAGVRVAALATPHRFGSAIGALAAAIRA--------GDA MMAR_0956|M.marinum_M --------LGARHDTHVAALRRLHRFGESIGQLAAAIRG--------GDA MUL_0707|M.ulcerans_Agy99 --------LGARHDTHVAALRRLHRFGESIGQLAAAIRG--------GDA MAB_0398c|M.abscessus_ATCC_199 --------LESER---VAALRTSHRFGAAIGALAAAVRD--------GDA MSMEG_1325|M.smegmatis_MC2_155 --------LGSRG---VAELKTSHRFGESIGALASAIRT--------GDA TH_3422|M.thermoresistible__bu LRRELPRFTDRPRTAFVDDLDDMIDWGTRLDHSCVAVQGPPGTGKTYRGA * * :* :. . *:: .. Mflv_5131|M.gilvum_PYR-GCK DATVEVLRAGGDA-----------------IGWLDTDDAADALRGPLVDR Mvan_1208|M.vanbaalenii_PYR-1 DTAVQLLRAGGDA-----------------VAWLDTDDPSDALRATLVAR Mb0645c|M.bovis_AF2122/97 DAVLGLLRSGEER-----------------IEFVDDEDPAPRLRAVLVPH Rv0629c|M.tuberculosis_H37Rv DAVLGLLRSGEER-----------------IEFVDDEDPAPRLRAVLVPH MAV_4544|M.avium_104 DRVVELLAAGGEH-----------------IEWVDSERPADRLREVLVSH MMAR_0956|M.marinum_M DRVVEILRAGDDH-----------------IEWINAADPTPQLRNVLLPH MUL_0707|M.ulcerans_Agy99 DRVVEILRAGDDH-----------------IEWINAADPTPQLRNVLLPH MAB_0398c|M.abscessus_ATCC_199 DRALEVLASGDPH-----------------VEWS-TDS--EGLRDVLVPQ MSMEG_1325|M.smegmatis_MC2_155 DAALAVLAAGGEH-----------------IEWV-HEDPVEQLREVVVPH TH_3422|M.thermoresistible__bu RMIRALVKAGKRVGITAISHYAIGNLLEGVVAAFRETDELDSLRAVCNPG :: :* : ** Mflv_5131|M.gilvum_PYR-GCK AADLREAALLGDGETALRILDGHRLLCAHRRGPFGVAHWNRQIERWLAER Mvan_1208|M.vanbaalenii_PYR-1 ADELRRAALLGDARAALGVLDGHRLLCAHRRGPFGVTHWNRQVERWLADK Mb0645c|M.bovis_AF2122/97 ALRLREAALLGASDVALATLDEHRLLCAHRDGPTGVLHWNRRVQAWLAEE Rv0629c|M.tuberculosis_H37Rv ALRLREAALLGASDVALATLDEHRLLCAHRDGPTGVLHWNRRVQAWLAEE MAV_4544|M.avium_104 ALRLRSAALLGAAQAALATLDEHRLLCAHRDGPHGAVRWNTLVHNWIAEE MMAR_0956|M.marinum_M ALELRRAGALGDTAAALATLDEQRLLCAHRRGPYGIAHWNHQVQRWLTEA MUL_0707|M.ulcerans_Agy99 ALELRRAGALGDTAAALATLDEQRLLCAHRRGPYGIAHWNHQVQRWLTEA MAB_0398c|M.abscessus_ATCC_199 ALALRAASLSGDATAALAVLDEHRMLCAHRHGPFGVTHWNRQVERWITEE MSMEG_1325|M.smegmatis_MC2_155 AMRLRQAAILGDQREALATLDEHRLLCAHRRGPAGVDHWNRQVQRWLGEE TH_3422|M.thermoresistible__bu KSALRRLPEIAYGGNKKCAREEYNVVAGTTWLFSSKEMRAAPVDVLVIDE ** . : .::.. . :. : : Mflv_5131|M.gilvum_PYR-GCK TGQSIWSQPYAGR---------------PLLVTANDYGLG---------- Mvan_1208|M.vanbaalenii_PYR-1 TGQPMWSQWYPGR---------------PLLVTANDYGLG---------- Mb0645c|M.bovis_AF2122/97 TGQPPWTPWYAGR---------------PLLVTANDYGLR---------- Rv0629c|M.tuberculosis_H37Rv TGQPPWTPWYAGR---------------PLLVTANDYGLR---------- MAV_4544|M.avium_104 TGQPAWSQWYAGR---------------PLLVTANDYGLR---------- MMAR_0956|M.marinum_M TGEPIWSSWYAGR---------------PVLVTANDYGLG---------- MUL_0707|M.ulcerans_Agy99 TGEPIWSSWYAGR---------------PVLVTANDYGLG---------- MAB_0398c|M.abscessus_ATCC_199 TGEPHWAPWYAGR---------------PILVTANDYGLR---------- MSMEG_1325|M.smegmatis_MC2_155 TGEPLWGSWYVGR---------------PILVTANDYGLK---------- TH_3422|M.thermoresistible__bu AGQLALADALAASGAAHNLVLLGDPLQLPQVAHANHPGIAGRSVLDHIVG :*: . * :. **. *: Mflv_5131|M.gilvum_PYR-GCK ------------------------------VYNG----------DTGVVV Mvan_1208|M.vanbaalenii_PYR-1 ------------------------------VYNG----------DTGVVV Mb0645c|M.bovis_AF2122/97 ------------------------------VYNG----------DTGVVL Rv0629c|M.tuberculosis_H37Rv ------------------------------VYNG----------DTGVVL MAV_4544|M.avium_104 ------------------------------LYNG----------DTGVTV MMAR_0956|M.marinum_M ------------------------------VYNG----------DTGVAV MUL_0707|M.ulcerans_Agy99 ------------------------------VYNG----------DTGVAV MAB_0398c|M.abscessus_ATCC_199 ------------------------------LYNG----------DTGVTV MSMEG_1325|M.smegmatis_MC2_155 ------------------------------LYNG----------DTGVVV TH_3422|M.thermoresistible__bu DDMLLPPDRGVFMHETRRMHPDVCAFISDQIYDGRLHSISDCNRQTTVAG :*:* :* *. Mflv_5131|M.gilvum_PYR-GCK AA-------PEGLRAHIGTPASSRELAVGRLG------------------ Mvan_1208|M.vanbaalenii_PYR-1 AA-------PDGLRAHVG----SLQFAPGRLG------------------ Mb0645c|M.bovis_AF2122/97 AG-------PTGLRAVISGASGPLDVATGRLG------------------ Rv0629c|M.tuberculosis_H37Rv AG-------PTGLRAVISGASGPLDVATGRLG------------------ MAV_4544|M.avium_104 AG-------ADGLRAVIAGAAGPLDFATSRLG------------------ MMAR_0956|M.marinum_M LDGTNRAAAPGALRVLIAGAQEPLKFATSRLS------------------ MUL_0707|M.ulcerans_Agy99 LDGTNRAAAPGALRVVIAGAQEPLKFATSRLS------------------ MAB_0398c|M.abscessus_ATCC_199 AG-------PDGLRAVIG-AAS---FATSRLV------------------ MSMEG_1325|M.smegmatis_MC2_155 AT-------PDGMRAVIGDAGT---FATGRLT------------------ TH_3422|M.thermoresistible__bu TGLRWMRVDHHGNRTRSPEEADAIADELTRLIGTPWTNQCGEEAPLRPQD . *. ** Mflv_5131|M.gilvum_PYR-GCK ----------------------EVETMFAMTIHKSQGSQADEVTVLMPPQ Mvan_1208|M.vanbaalenii_PYR-1 ----------------------EVETMFAMTIHKSQGSQADEVTVLLPPQ Mb0645c|M.bovis_AF2122/97 ----------------------DVETMHAMTIHKSQGSQVDEVTVLMPQE Rv0629c|M.tuberculosis_H37Rv ----------------------DVETMHAMTIHKSQGSQVDEVTVLMPQE MAV_4544|M.avium_104 ----------------------EVETMHAMTIHKSQGSQADEVTVLIPPE MMAR_0956|M.marinum_M ----------------------DVETMHAMTIHKSQGSQADDVTVLLPPA MUL_0707|M.ulcerans_Agy99 ----------------------DVETMHAMTIHKSQGSQADDVTVLLPPA MAB_0398c|M.abscessus_ATCC_199 ----------------------EVETMHAMTIHKSQGSQANEVTVLLPSE MSMEG_1325|M.smegmatis_MC2_155 ----------------------DVETMHAMTIHKSQGSQADEVTVLLPSE TH_3422|M.thermoresistible__bu VMVVAPYNLQVNTIRARLRQDPRLADVPVGTVDKFQGREAAVVFFSMASS : : . *:.* ** :. * . :. Mflv_5131|M.gilvum_PYR-GCK DSR--------LLTRELFYTAVTRAKERVQVVGTEASVR----------- Mvan_1208|M.vanbaalenii_PYR-1 DSR--------LLTRELFYTAVTRAKKHVRVVGTEASVR----------- Mb0645c|M.bovis_AF2122/97 DSR--------LLTRELLYTAVARAKRKVRVVGSEASVR----------- Rv0629c|M.tuberculosis_H37Rv DSR--------LLTRELLYTAVTRAKRKVRVVGSEASVR----------- MAV_4544|M.avium_104 DSR--------LLTRELFYTAVTRAKSRVRVVGPEASVR----------- MMAR_0956|M.marinum_M DSR--------LLTRELFYTAVTRAARKVRIVGPECDVR----------- MUL_0707|M.ulcerans_Agy99 DSR--------LLTRELFYTAVTRAARKVRIVGPECDVR----------- MAB_0398c|M.abscessus_ATCC_199 DSR--------LLTRELFYTAVTRAKQRVRVVGSEAEVR----------- MSMEG_1325|M.smegmatis_MC2_155 DSR--------LLTRELFYTAVTRAKTRVRVVGAEAEVR----------- TH_3422|M.thermoresistible__bu SGEDISRGVDFLLSRNRLNVAVSRARCLAYLVCTDALLDTRARTVEDMRL ... **:*: : .**:** . :* .:. : Mflv_5131|M.gilvum_PYR-GCK -AAVGRRAVRASGLARRLSTAR-- Mvan_1208|M.vanbaalenii_PYR-1 -TAIGRRATRASGLAQRLRTRP-- Mb0645c|M.bovis_AF2122/97 -AAIARRAVRASGLRMRLQSTGCG Rv0629c|M.tuberculosis_H37Rv -AAIARRAVRASGLRMRLQSTGCG MAV_4544|M.avium_104 -AAIERRAIRATGLRQRLRVVG-- MMAR_0956|M.marinum_M -AAIARRAIRATGLRSRLQP---- MUL_0707|M.ulcerans_Agy99 -AAIARRAIRATGLRSRLQP---- MAB_0398c|M.abscessus_ATCC_199 -AAIQRQAVRASGLGRRLRHSPN- MSMEG_1325|M.smegmatis_MC2_155 -AAIERQAVRATGLRKRLRPAGV- TH_3422|M.thermoresistible__bu VATLNAFVEAAQPVTPVPSTAGC- ::: . * :