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M. avium 104 MAV_4544 (recD)

annotation: exodeoxyribonuclease V, alpha subunit
coordinates: 4674395 - 4676107
length: 570

VLPERVFDAGPLRPFADAGIFEAADIHVAQRLTALTGESDDRVALAVALLVRALRGGSVCVDLRAVPAQV
GAADLPWPAAGDWLAAVRASPLLGPPPVLRFFGDLLYFDRYWLEEEQVCTDLLALSAPAGDVESSCYERL
FPPGYEEQRAAARIAVSQALTVLTGGPGTGKTTTVARLLALLVEQAERAGEPRPRIALAAPTGKAAARLA
EAVAAEIEHLDPADRARLAGLTGTTLHRLLGPRPDTSVRFKHNRGNRLPHDIIVVDETSMVSLTMMARLA
EAVRPDTRLILVGDPDQLASVEAGAVLADLVDGLAGRAGVRVAALATPHRFGSAIGALAAAIRAGDADRV
VELLAAGGEHIEWVDSERPADRLREVLVSHALRLRSAALLGAAQAALATLDEHRLLCAHRDGPHGAVRWN
TLVHNWIAEETGQPAWSQWYAGRPLLVTANDYGLRLYNGDTGVTVAGADGLRAVIAGAAGPLDFATSRLG
EVETMHAMTIHKSQGSQADEVTVLIPPEDSRLLTRELFYTAVTRAKSRVRVVGPEASVRAAIERRAIRAT
GLRQRLRVVG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_4544recD-100% (570)exodeoxyribonuclease V, alpha subunit
M. avium 104MAV_1388-3e-0627.31% (216) ATPase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0645crecD0.071.40% (563) exonuclease V alpha chain
M. gilvum PYR-GCKMflv_5131-0.069.15% (551) exodeoxyribonuclease V, alpha subunit
M. tuberculosis H37RvRv0629crecD0.071.58% (563) exonuclease V alpha chain
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0398c-0.074.55% (550) exodeoxyribonuclease V, alpha subunit (RecD)
M. marinum MMMAR_0956recD0.070.30% (569) exodeoxyribonuclease V (alpha chain), RecD
M. smegmatis MC2 155MSMEG_1325recD0.072.89% (557) exodeoxyribonuclease V, alpha subunit
M. thermoresistible (build 8)TH_3422-2e-0525.93% (162) PUTATIVE conserved hypothetical protein
M. ulcerans Agy99MUL_0707recD0.070.30% (569) exodeoxyribonuclease V (alpha chain), RecD
M. vanbaalenii PYR-1Mvan_1208-0.070.80% (548) exodeoxyribonuclease V, alpha subunit

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5131|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1208|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0645c|M.bovis_AF2122/97           --------------------------------------------------
Rv0629c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_4544|M.avium_104                --------------------------------------------------
MMAR_0956|M.marinum_M               --------------------------------------------------
MUL_0707|M.ulcerans_Agy99           --------------------------------------------------
MAB_0398c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_1325|M.smegmatis_MC2_155      --------------------------------------------------
TH_3422|M.thermoresistible__bu      VTTTVTERLLTPSKVTAWLDCPHYLSLCAQVDDGILPRPESRFGSFAELL
                                                                                      

Mflv_5131|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1208|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0645c|M.bovis_AF2122/97           --------------------------------------------------
Rv0629c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_4544|M.avium_104                --------------------------------------------------
MMAR_0956|M.marinum_M               --------------------------------------------------
MUL_0707|M.ulcerans_Agy99           --------------------------------------------------
MAB_0398c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_1325|M.smegmatis_MC2_155      --------------------------------------------------
TH_3422|M.thermoresistible__bu      LDKGRAHEQACLADFERQGKRVLRIPDRENGESFAAWVARVGNPLTDDHD
                                                                                      

Mflv_5131|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1208|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0645c|M.bovis_AF2122/97           --------------------------------------------------
Rv0629c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_4544|M.avium_104                --------------------------------------------------
MMAR_0956|M.marinum_M               --------------------------------------------------
MUL_0707|M.ulcerans_Agy99           --------------------------------------------------
MAB_0398c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_1325|M.smegmatis_MC2_155      --------------------------------------------------
TH_3422|M.thermoresistible__bu      VIYQMPFVHNGIAGIADFLVRVTHPDTGEVSWEPVDAKLTRIEAKPGHVL
                                                                                      

Mflv_5131|M.gilvum_PYR-GCK          --------------------------MSLDAF------------------
Mvan_1208|M.vanbaalenii_PYR-1       --------------------------MTVEAF------------------
Mb0645c|M.bovis_AF2122/97           -------------MKLTDVDFAVEASGMVRAFNQ----------------
Rv0629c|M.tuberculosis_H37Rv        -------------MKLTDVDFAVEASGMVRAFNQ----------------
MAV_4544|M.avium_104                --------------MLPER---VFDAGPLRPFAD----------------
MMAR_0956|M.marinum_M               --------MTIDVVDPADWRQAASASGPLRTFNE----------------
MUL_0707|M.ulcerans_Agy99           --------MTIEVVDPADWRQAASASGPLRTFNE----------------
MAB_0398c|M.abscessus_ATCC_199      -------------------------MSLVEAF------------------
MSMEG_1325|M.smegmatis_MC2_155      -------------------------MSLLEAF------------------
TH_3422|M.thermoresistible__bu      QLCFYADALEALTGRRPEHMHIWLGSGQLETLRVNEFQPYWRRLQTQLAA
                                                                : .:                  

Mflv_5131|M.gilvum_PYR-GCK          ----------------------------------AEVFEPADIHVAQR--
Mvan_1208|M.vanbaalenii_PYR-1       ----------------------------------SELFEPADLHVAQR--
Mb0645c|M.bovis_AF2122/97           ----------------------------------AGVLDVSDVHVAQR--
Rv0629c|M.tuberculosis_H37Rv        ----------------------------------AGVLDVSDVHVAQR--
MAV_4544|M.avium_104                ----------------------------------AGIFEAADIHVAQR--
MMAR_0956|M.marinum_M               ----------------------------------AGVIDAADVHVAQR--
MUL_0707|M.ulcerans_Agy99           ----------------------------------ARVIDAADVHVAQR--
MAB_0398c|M.abscessus_ATCC_199      ----------------------------------GEILEPADVHVAQR--
MSMEG_1325|M.smegmatis_MC2_155      ----------------------------------AEILEPADVHVAQR--
TH_3422|M.thermoresistible__bu      ALAAGPEAGTVAEQCAHCEFCEFQPTCEMYWRDTDSLIYVANIRKPDREA
                                                                        ::  :::: .:*  

Mflv_5131|M.gilvum_PYR-GCK          --------LTELGRDSDPTVALAVALAVRAVRSGSVCVDLRTVAAQVGVP
Mvan_1208|M.vanbaalenii_PYR-1       --------LTTLGKEGDDSVALAVALAVRALRGGSVCVDLRAIATQVGMP
Mb0645c|M.bovis_AF2122/97           --------LCALAGESDERVALAVAVAVRALRAGSVCVDLLSIARVAGHD
Rv0629c|M.tuberculosis_H37Rv        --------LCALAGESDERVALAVAVAVRALRAGSVCVDLLSIARVAGHD
MAV_4544|M.avium_104                --------LTALTGESDDRVALAVALLVRALRGGSVCVDLRAVPAQVGAA
MMAR_0956|M.marinum_M               --------LAAMSGESDPVVLLAIAFVVRALRGGSVCVDLSTIEAQVGIA
MUL_0707|M.ulcerans_Agy99           --------LAAMSGESDPVVLLAIAFVVRALRGGSVCVDLSTIEAQVGIA
MAB_0398c|M.abscessus_ATCC_199      --------LTALASETDESVELAIALAVRALRGGSVCVDLRAVAAQVDMP
MSMEG_1325|M.smegmatis_MC2_155      --------LTVLADEPDASVELAVALAVRALRGGSVCVDLRSVAGQVELP
TH_3422|M.thermoresistible__bu      LAGADIATLTALATSDGPVEGMDPDRLARLRRQAALQLAAREQQREKPPF
                                            *  :  . .    :     .*  * .:: :            

Mflv_5131|M.gilvum_PYR-GCK          ELPWPDPDGWLSTVGASP-LAEHK-VVRLDGD-LLYLDR-----------
Mvan_1208|M.vanbaalenii_PYR-1       ELPWPEPDRWLAAVGASP-LADER-VLRMHGD-LLYLDR-----------
Mb0645c|M.bovis_AF2122/97           DLPWPDPADWLAAVRASP-LLADPPVLHLYDDRLLYLDR-----------
Rv0629c|M.tuberculosis_H37Rv        DLPWPDPADWLAAVRASP-LLADPPVLHLYDDRLLYLDR-----------
MAV_4544|M.avium_104                DLPWPAAGDWLAAVRASP-LLGPPPVLRFFGD-LLYFDR-----------
MMAR_0956|M.marinum_M               DLPWPAAGEWLAAVRASP-LVGSPAVLRLHEDNLVYLDR-----------
MUL_0707|M.ulcerans_Agy99           DLPWPAAGEWLAAVRASP-LVGSPAVLRLHEDNLVYLDR-----------
MAB_0398c|M.abscessus_ATCC_199      SLPWPAADDWLAAVRASP-LAGEPPVLRLFGD-LLYLDR-----------
MSMEG_1325|M.smegmatis_MC2_155      DLPWPDPDAWLAALAASP-LLGQPPVLRLFGD-LLYLDR-----------
TH_3422|M.thermoresistible__bu      ELIRPGPEPWGHGFEMLPEPDGGDVFLDFEGHPFWRADTGLFFLFGLIEQ
                                    .*  * .  *   .   *       .: :  . :   *            

Mflv_5131|M.gilvum_PYR-GCK          -----------YWREEEQVRDDVVALLSS--PPRTAVPGLERLFPAGWEE
Mvan_1208|M.vanbaalenii_PYR-1       -----------YWREEQQVCDDVLALLAS--PLPATAPSIERLFPAGWEE
Mb0645c|M.bovis_AF2122/97           -----------YWREEEQVCADLLALLTS--RRPAGVPDLRRLFPTGFDE
Rv0629c|M.tuberculosis_H37Rv        -----------YWREEEQVCADLLALLTS--RRPAGVPDLRRLFPTGFDE
MAV_4544|M.avium_104                -----------YWLEEEQVCTDLLALSAP--AGDVESSCYERLFPPGYEE
MMAR_0956|M.marinum_M               -----------YWREEQQVADDILALLAARASASGPAIEVNRLFPPGYEE
MUL_0707|M.ulcerans_Agy99           -----------YWREEQQVADDILALLAARASASGPAIEVNRLFPPGYEE
MAB_0398c|M.abscessus_ATCC_199      -----------YWREEQQVCTDVQALMAA-AQPRTEVPTYERLFPQGFEE
MSMEG_1325|M.smegmatis_MC2_155      -----------YWLEEQQVCDDVLALVS--ARPGGAVPDVSRLFGAGFEE
TH_3422|M.thermoresistible__bu      DDDGGRWRYRCWWAHDRDEEAAAVAQLVEYLVERRKQHPAMHVYHYNHTE
                                               :* .:.:      *                :::  .  *

Mflv_5131|M.gilvum_PYR-GCK          QRAAAEAALTRSLTVLTGGP------------------------------
Mvan_1208|M.vanbaalenii_PYR-1       QREAAKVALRQSLTVLTGGP------------------------------
Mb0645c|M.bovis_AF2122/97           QRRAAEIALSQGVTVLTGGP------------------------------
Rv0629c|M.tuberculosis_H37Rv        QRRAAEIALSQGVTVLTGGP------------------------------
MAV_4544|M.avium_104                QRAAARIAVSQALTVLTGGP------------------------------
MMAR_0956|M.marinum_M               QRAAAKIALAQGLTVLTGGP------------------------------
MUL_0707|M.ulcerans_Agy99           QRAAAKIALAQGLTVLTGGP------------------------------
MAB_0398c|M.abscessus_ATCC_199      QRAAADIALSQGLTVLTGGP------------------------------
MSMEG_1325|M.smegmatis_MC2_155      QRAAAKVALSQGLTVLTGGP------------------------------
TH_3422|M.thermoresistible__bu      RSALQRMAEEHGVAELALAELIDTGAFVDLLLVARNSIQVGAESYGLKHL
                                    :      *  :.:: *: .                               

Mflv_5131|M.gilvum_PYR-GCK          --------------------------GTGKTTTVARLLAAFAEQAELAGG
Mvan_1208|M.vanbaalenii_PYR-1       --------------------------GTGKTTTVARLLASIAEQAESAGG
Mb0645c|M.bovis_AF2122/97           --------------------------GTGKTTTVARLLALVAEQAELAGE
Rv0629c|M.tuberculosis_H37Rv        --------------------------GTGKTTTVARLLALVAEQAELAGE
MAV_4544|M.avium_104                --------------------------GTGKTTTVARLLALLVEQAERAGE
MMAR_0956|M.marinum_M               --------------------------GTGKTTTVARLLALFAEQAQLAGK
MUL_0707|M.ulcerans_Agy99           --------------------------GTGKTTTVARLLALFAEQAQLAGK
MAB_0398c|M.abscessus_ATCC_199      --------------------------GTGKTTTVARLLALLADQASSASA
MSMEG_1325|M.smegmatis_MC2_155      --------------------------GTGKTTTVARLLALLAEQAALAGK
TH_3422|M.thermoresistible__bu      ERLTDFERSHDIDQGAGAVVQYEQYIADGNQAHLDAIAAYNADDVRATLA
                                                              . *: : :  : *  .::.  :  

Mflv_5131|M.gilvum_PYR-GCK          PPPRMALAAPTGKAAARLQDAVQAEVDRLSAVDR----------------
Mvan_1208|M.vanbaalenii_PYR-1       APPRMALAAPTGKAAARLQDAVHAEVGKLPAVDQ----------------
Mb0645c|M.bovis_AF2122/97           PRPRIALAAPTGKAAARLAEAVRREMAKLDATDR----------------
Rv0629c|M.tuberculosis_H37Rv        PRPRIALAAPTGKAAARLAEAVRREMAKLDATDR----------------
MAV_4544|M.avium_104                PRPRIALAAPTGKAAARLAEAVAAEIEHLDPADR----------------
MMAR_0956|M.marinum_M               ARLRIALAAPTGKAAARLHEAVQSQIDKLDAIDQ----------------
MUL_0707|M.ulcerans_Agy99           ARLRIALAAPTGKAAARLHEAVQSQIDKLDAIDQ----------------
MAB_0398c|M.abscessus_ATCC_199      APLRIALAAPTGKAAARLQEAVQLEVNQLDAVDR----------------
MSMEG_1325|M.smegmatis_MC2_155      PSPRIALAAPTGKAAARLQEAVQLEIDQLDLIER----------------
TH_3422|M.thermoresistible__bu      LRDWLVEHRPPGLPWRSAVLEPDPELPGLGETVERLHQFPVGSDEHNLGD
                                        :.   *.* .          ::  *    .                

Mflv_5131|M.gilvum_PYR-GCK          -------------------------------ARLAGLRATTMHRLLG--S
Mvan_1208|M.vanbaalenii_PYR-1       -------------------------------GRLAGLRATTLHRLLG--S
Mb0645c|M.bovis_AF2122/97           -------------------------------ARLGDLHAVTLHRLLG--A
Rv0629c|M.tuberculosis_H37Rv        -------------------------------ARLGDLHAVTLHRLLG--A
MAV_4544|M.avium_104                -------------------------------ARLAGLTGTTLHRLLG--P
MMAR_0956|M.marinum_M               -------------------------------QRVRGLQATTLHRLLG--S
MUL_0707|M.ulcerans_Agy99           -------------------------------QRVRGLQATTLHRLLG--S
MAB_0398c|M.abscessus_ATCC_199      -------------------------------SRLAGLQATTLHRLLG--S
MSMEG_1325|M.smegmatis_MC2_155      -------------------------------RRLTGLHATTLHRLLG--P
TH_3422|M.thermoresistible__bu      LLNYWRDEGLAYIAPKNAKLATDPVDLYDDAEVIADLRPETLLESTGRAR
                                                                     : .*   *: .  *   

Mflv_5131|M.gilvum_PYR-GCK          RPDTSSRFRHHRGNRLPHD---VIVVDET------SMVSLTMMARLLEAV
Mvan_1208|M.vanbaalenii_PYR-1       RPDTSSRFRHHRDNRLPHD---VIVVDET------SMVSLTMMARLLEAV
Mb0645c|M.bovis_AF2122/97           KP--GARFRQDRQNRLPHN---VIVVDET------SMVSLTLMARLAEAV
Rv0629c|M.tuberculosis_H37Rv        KP--GARFRQDRQNRLPHN---VIVVDET------SMVSLTLMARLAEAV
MAV_4544|M.avium_104                RPDTSVRFKHNRGNRLPHD---IIVVDET------SMVSLTMMARLAEAV
MMAR_0956|M.marinum_M               RPDTSSRFRHHRGNRLPHD---VIVIDET------SMVSLTMMARLLEAV
MUL_0707|M.ulcerans_Agy99           RPDTSSRFRHHRGNRLPHD---VIVIDET------SMVSLTMMARLLEAV
MAB_0398c|M.abscessus_ATCC_199      RPDTSSRFKHDRGNRLPHD---VIVVDET------SMVSLTMMARLLEAV
MSMEG_1325|M.smegmatis_MC2_155      RPDTSSRFRHHRANRLPHD---VIVVDET------SMVSLTMMARLLEAV
TH_3422|M.thermoresistible__bu      HPRRRFRFPDQDVDRFPSDGGSVMVATSTGERLCTGIANLDRDAHTLDLV
                                    :*    ** ..  :*:* :   ::*  .*      .:..*   *:  : *

Mflv_5131|M.gilvum_PYR-GCK          R----------PDTRLLFVGDPDQLASVDAGAVLADLVDG----------
Mvan_1208|M.vanbaalenii_PYR-1       R----------PDTRLLFVGDPDQLASVDAGAVLADLVEG----------
Mb0645c|M.bovis_AF2122/97           R----------PGARLILVGDADQLASVEAGAVLADLVDG----------
Rv0629c|M.tuberculosis_H37Rv        R----------PGARLILVGDADQLASVEAGAVLADLVDG----------
MAV_4544|M.avium_104                R----------PDTRLILVGDPDQLASVEAGAVLADLVDG----------
MMAR_0956|M.marinum_M               R----------PQTRLLLVGDPDQLASVEAGAVLADLVDG----------
MUL_0707|M.ulcerans_Agy99           R----------PQTRLLLVGDPDQLASVEAGAVLADLVDG----------
MAB_0398c|M.abscessus_ATCC_199      R----------PQARLLLVGDPDQLASVEAGAVLADLVEG----------
MSMEG_1325|M.smegmatis_MC2_155      R----------PQTRLVLVGDPDQLASVEAGAVLADLVEG----------
TH_3422|M.thermoresistible__bu      WNDKLQEAGCPPRIAVLHDWVKSEVKVKALQAFAEDLLDGRNPNPVTLAL
                                               *   ::     .::      *.  **::*          

Mflv_5131|M.gilvum_PYR-GCK          --------LGEAG---VVELTTSHRFGERIGALALAIRS--------GDA
Mvan_1208|M.vanbaalenii_PYR-1       --------LGDAG---VVELKTPHRFGETIGSLAEAIRA--------GDA
Mb0645c|M.bovis_AF2122/97           --------FSVRDDALVAQLRTSHRFGKVIGTLAEAIRA--------GDG
Rv0629c|M.tuberculosis_H37Rv        --------FSVRDDALVAQLRTSHRFGKVIGTLAEAIRA--------GDG
MAV_4544|M.avium_104                --------LAGRAGVRVAALATPHRFGSAIGALAAAIRA--------GDA
MMAR_0956|M.marinum_M               --------LGARHDTHVAALRRLHRFGESIGQLAAAIRG--------GDA
MUL_0707|M.ulcerans_Agy99           --------LGARHDTHVAALRRLHRFGESIGQLAAAIRG--------GDA
MAB_0398c|M.abscessus_ATCC_199      --------LESER---VAALRTSHRFGAAIGALAAAVRD--------GDA
MSMEG_1325|M.smegmatis_MC2_155      --------LGSRG---VAELKTSHRFGESIGALASAIRT--------GDA
TH_3422|M.thermoresistible__bu      LRRELPRFTDRPRTAFVDDLDDMIDWGTRLDHSCVAVQGPPGTGKTYRGA
                                                    *  *     :*  :.  . *::          ..

Mflv_5131|M.gilvum_PYR-GCK          DATVEVLRAGGDA-----------------IGWLDTDDAADALRGPLVDR
Mvan_1208|M.vanbaalenii_PYR-1       DTAVQLLRAGGDA-----------------VAWLDTDDPSDALRATLVAR
Mb0645c|M.bovis_AF2122/97           DAVLGLLRSGEER-----------------IEFVDDEDPAPRLRAVLVPH
Rv0629c|M.tuberculosis_H37Rv        DAVLGLLRSGEER-----------------IEFVDDEDPAPRLRAVLVPH
MAV_4544|M.avium_104                DRVVELLAAGGEH-----------------IEWVDSERPADRLREVLVSH
MMAR_0956|M.marinum_M               DRVVEILRAGDDH-----------------IEWINAADPTPQLRNVLLPH
MUL_0707|M.ulcerans_Agy99           DRVVEILRAGDDH-----------------IEWINAADPTPQLRNVLLPH
MAB_0398c|M.abscessus_ATCC_199      DRALEVLASGDPH-----------------VEWS-TDS--EGLRDVLVPQ
MSMEG_1325|M.smegmatis_MC2_155      DAALAVLAAGGEH-----------------IEWV-HEDPVEQLREVVVPH
TH_3422|M.thermoresistible__bu      RMIRALVKAGKRVGITAISHYAIGNLLEGVVAAFRETDELDSLRAVCNPG
                                         :: :*                    :           **      

Mflv_5131|M.gilvum_PYR-GCK          AADLREAALLGDGETALRILDGHRLLCAHRRGPFGVAHWNRQIERWLAER
Mvan_1208|M.vanbaalenii_PYR-1       ADELRRAALLGDARAALGVLDGHRLLCAHRRGPFGVTHWNRQVERWLADK
Mb0645c|M.bovis_AF2122/97           ALRLREAALLGASDVALATLDEHRLLCAHRDGPTGVLHWNRRVQAWLAEE
Rv0629c|M.tuberculosis_H37Rv        ALRLREAALLGASDVALATLDEHRLLCAHRDGPTGVLHWNRRVQAWLAEE
MAV_4544|M.avium_104                ALRLRSAALLGAAQAALATLDEHRLLCAHRDGPHGAVRWNTLVHNWIAEE
MMAR_0956|M.marinum_M               ALELRRAGALGDTAAALATLDEQRLLCAHRRGPYGIAHWNHQVQRWLTEA
MUL_0707|M.ulcerans_Agy99           ALELRRAGALGDTAAALATLDEQRLLCAHRRGPYGIAHWNHQVQRWLTEA
MAB_0398c|M.abscessus_ATCC_199      ALALRAASLSGDATAALAVLDEHRMLCAHRHGPFGVTHWNRQVERWITEE
MSMEG_1325|M.smegmatis_MC2_155      AMRLRQAAILGDQREALATLDEHRLLCAHRRGPAGVDHWNRQVQRWLGEE
TH_3422|M.thermoresistible__bu      KSALRRLPEIAYGGNKKCAREEYNVVAGTTWLFSSKEMRAAPVDVLVIDE
                                       **     .         :  .::..      .       :.  : : 

Mflv_5131|M.gilvum_PYR-GCK          TGQSIWSQPYAGR---------------PLLVTANDYGLG----------
Mvan_1208|M.vanbaalenii_PYR-1       TGQPMWSQWYPGR---------------PLLVTANDYGLG----------
Mb0645c|M.bovis_AF2122/97           TGQPPWTPWYAGR---------------PLLVTANDYGLR----------
Rv0629c|M.tuberculosis_H37Rv        TGQPPWTPWYAGR---------------PLLVTANDYGLR----------
MAV_4544|M.avium_104                TGQPAWSQWYAGR---------------PLLVTANDYGLR----------
MMAR_0956|M.marinum_M               TGEPIWSSWYAGR---------------PVLVTANDYGLG----------
MUL_0707|M.ulcerans_Agy99           TGEPIWSSWYAGR---------------PVLVTANDYGLG----------
MAB_0398c|M.abscessus_ATCC_199      TGEPHWAPWYAGR---------------PILVTANDYGLR----------
MSMEG_1325|M.smegmatis_MC2_155      TGEPLWGSWYVGR---------------PILVTANDYGLK----------
TH_3422|M.thermoresistible__bu      AGQLALADALAASGAAHNLVLLGDPLQLPQVAHANHPGIAGRSVLDHIVG
                                    :*:        .                * :. **. *:           

Mflv_5131|M.gilvum_PYR-GCK          ------------------------------VYNG----------DTGVVV
Mvan_1208|M.vanbaalenii_PYR-1       ------------------------------VYNG----------DTGVVV
Mb0645c|M.bovis_AF2122/97           ------------------------------VYNG----------DTGVVL
Rv0629c|M.tuberculosis_H37Rv        ------------------------------VYNG----------DTGVVL
MAV_4544|M.avium_104                ------------------------------LYNG----------DTGVTV
MMAR_0956|M.marinum_M               ------------------------------VYNG----------DTGVAV
MUL_0707|M.ulcerans_Agy99           ------------------------------VYNG----------DTGVAV
MAB_0398c|M.abscessus_ATCC_199      ------------------------------LYNG----------DTGVTV
MSMEG_1325|M.smegmatis_MC2_155      ------------------------------LYNG----------DTGVVV
TH_3422|M.thermoresistible__bu      DDMLLPPDRGVFMHETRRMHPDVCAFISDQIYDGRLHSISDCNRQTTVAG
                                                                  :*:*          :* *. 

Mflv_5131|M.gilvum_PYR-GCK          AA-------PEGLRAHIGTPASSRELAVGRLG------------------
Mvan_1208|M.vanbaalenii_PYR-1       AA-------PDGLRAHVG----SLQFAPGRLG------------------
Mb0645c|M.bovis_AF2122/97           AG-------PTGLRAVISGASGPLDVATGRLG------------------
Rv0629c|M.tuberculosis_H37Rv        AG-------PTGLRAVISGASGPLDVATGRLG------------------
MAV_4544|M.avium_104                AG-------ADGLRAVIAGAAGPLDFATSRLG------------------
MMAR_0956|M.marinum_M               LDGTNRAAAPGALRVLIAGAQEPLKFATSRLS------------------
MUL_0707|M.ulcerans_Agy99           LDGTNRAAAPGALRVVIAGAQEPLKFATSRLS------------------
MAB_0398c|M.abscessus_ATCC_199      AG-------PDGLRAVIG-AAS---FATSRLV------------------
MSMEG_1325|M.smegmatis_MC2_155      AT-------PDGMRAVIGDAGT---FATGRLT------------------
TH_3422|M.thermoresistible__bu      TGLRWMRVDHHGNRTRSPEEADAIADELTRLIGTPWTNQCGEEAPLRPQD
                                               . *.              **                   

Mflv_5131|M.gilvum_PYR-GCK          ----------------------EVETMFAMTIHKSQGSQADEVTVLMPPQ
Mvan_1208|M.vanbaalenii_PYR-1       ----------------------EVETMFAMTIHKSQGSQADEVTVLLPPQ
Mb0645c|M.bovis_AF2122/97           ----------------------DVETMHAMTIHKSQGSQVDEVTVLMPQE
Rv0629c|M.tuberculosis_H37Rv        ----------------------DVETMHAMTIHKSQGSQVDEVTVLMPQE
MAV_4544|M.avium_104                ----------------------EVETMHAMTIHKSQGSQADEVTVLIPPE
MMAR_0956|M.marinum_M               ----------------------DVETMHAMTIHKSQGSQADDVTVLLPPA
MUL_0707|M.ulcerans_Agy99           ----------------------DVETMHAMTIHKSQGSQADDVTVLLPPA
MAB_0398c|M.abscessus_ATCC_199      ----------------------EVETMHAMTIHKSQGSQANEVTVLLPSE
MSMEG_1325|M.smegmatis_MC2_155      ----------------------DVETMHAMTIHKSQGSQADEVTVLLPSE
TH_3422|M.thermoresistible__bu      VMVVAPYNLQVNTIRARLRQDPRLADVPVGTVDKFQGREAAVVFFSMASS
                                                           :  : . *:.* ** :.  * . :.  

Mflv_5131|M.gilvum_PYR-GCK          DSR--------LLTRELFYTAVTRAKERVQVVGTEASVR-----------
Mvan_1208|M.vanbaalenii_PYR-1       DSR--------LLTRELFYTAVTRAKKHVRVVGTEASVR-----------
Mb0645c|M.bovis_AF2122/97           DSR--------LLTRELLYTAVARAKRKVRVVGSEASVR-----------
Rv0629c|M.tuberculosis_H37Rv        DSR--------LLTRELLYTAVTRAKRKVRVVGSEASVR-----------
MAV_4544|M.avium_104                DSR--------LLTRELFYTAVTRAKSRVRVVGPEASVR-----------
MMAR_0956|M.marinum_M               DSR--------LLTRELFYTAVTRAARKVRIVGPECDVR-----------
MUL_0707|M.ulcerans_Agy99           DSR--------LLTRELFYTAVTRAARKVRIVGPECDVR-----------
MAB_0398c|M.abscessus_ATCC_199      DSR--------LLTRELFYTAVTRAKQRVRVVGSEAEVR-----------
MSMEG_1325|M.smegmatis_MC2_155      DSR--------LLTRELFYTAVTRAKTRVRVVGAEAEVR-----------
TH_3422|M.thermoresistible__bu      SGEDISRGVDFLLSRNRLNVAVSRARCLAYLVCTDALLDTRARTVEDMRL
                                    ...        **:*: : .**:**   . :* .:. :            

Mflv_5131|M.gilvum_PYR-GCK          -AAVGRRAVRASGLARRLSTAR--
Mvan_1208|M.vanbaalenii_PYR-1       -TAIGRRATRASGLAQRLRTRP--
Mb0645c|M.bovis_AF2122/97           -AAIARRAVRASGLRMRLQSTGCG
Rv0629c|M.tuberculosis_H37Rv        -AAIARRAVRASGLRMRLQSTGCG
MAV_4544|M.avium_104                -AAIERRAIRATGLRQRLRVVG--
MMAR_0956|M.marinum_M               -AAIARRAIRATGLRSRLQP----
MUL_0707|M.ulcerans_Agy99           -AAIARRAIRATGLRSRLQP----
MAB_0398c|M.abscessus_ATCC_199      -AAIQRQAVRASGLGRRLRHSPN-
MSMEG_1325|M.smegmatis_MC2_155      -AAIERQAVRATGLRKRLRPAGV-
TH_3422|M.thermoresistible__bu      VATLNAFVEAAQPVTPVPSTAGC-
                                     :::   .  *  :