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VAPTGQAVDVAVREGAGDVGYSVERENLPADDPVRNGNRWRVIAVDTEHHRIAARRLGDGARAAFSGDYL HEHITHGYAITVHASQGTTAHSTHAVLGDNTSRATLYVAMTPARESNTAYLCERTAGEGARVDLAGWDLW VSGKAEAMSDEKSASPVWCRVGARCDHRGKRSCW
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv2311 | - | - | 100% (174) | hypothetical protein Rv2311 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2338 | - | 1e-102 | 100.00% (174) | hypothetical protein Mb2338 |
M. gilvum PYR-GCK | Mflv_2792 | - | 5e-10 | 35.92% (103) | exonuclease V subunit alpha |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_3605 | - | 5e-38 | 74.23% (97) | ATP-dependent exoDNAse (exonuclease V) |
M. avium 104 | - | - | - | - | - |
M. smegmatis MC2 155 | - | - | - | - | - |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_3254 | - | 1e-11 | 38.95% (95) | exonuclease V subunit alpha |
CLUSTAL 2.0.9 multiple sequence alignment Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -----------------------MLTIAKLSRWSINYYNDTARAAGAAAA Mflv_2792|M.gilvum_PYR-GCK MVMTLHKLTAGDGYLYLVRQVAAADSTERGRSTLADYYSAKGESPGRWMG Mvan_3254|M.vanbaalenii_PYR-1 --MSMHKLTAGDGYLYLVRQVAAADSTERGRSSLADYYSAKGESPGRWMG Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M DAQRAGGGLGEYYAEHDTRTPVWLCAG----------------------- Mflv_2792|M.gilvum_PYR-GCK RGLAALSNTGRFEVSPTAREEIWTVEEGSGVSETQMRALYGVGLHPNAQR Mvan_3254|M.vanbaalenii_PYR-1 RGLAALADTGAREVSDEVRQNVWAVEGGSVVTEAQMKALFGLGWHPNADK Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M ------------DAHTAAKLVGLTDVQRAGGPADPEVVQRWLDDGTAPNG Mflv_2792|M.gilvum_PYR-GCK IQTYVTGHN-MGNQRAASRLGREFQVRDG-KPEFSRRLAVAFRDHNAEIG Mvan_3254|M.vanbaalenii_PYR-1 IYGHLSPRLGVQPATAAGQLGRKYPAQEEPSSEFTRRVGKAFRAHNIEAG Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M ASG------------------------------------------RAFGN Mflv_2792|M.gilvum_PYR-GCK AHWNATIGPEIRSGIRTRMAMELFGEEYGRPPADDRELSGFIARNTRAKT Mvan_3254|M.vanbaalenii_PYR-1 LAGNATIDDDVRAGIRTQVAREMFAEQFGRDPADDRELSGFVARATRART Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M RGVHGFDLTFCAPKSVSLIRALRAGDVADKAIATAHATAVSEALEYLAAH Mflv_2792|M.gilvum_PYR-GCK TAVAGYDLTFSPVKSVSALWAIAP-LPVAEQIEAAHDAAVADVLEWLQEQ Mvan_3254|M.vanbaalenii_PYR-1 TAVAGYDLTFSPVKSISALWAIAP-PEIAEQIEAAHEAAVADVLEWLQDK Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M AGYTRVHNPVTGEKDLLRLPGLVAIAYQHETSRAGDPHLHTHVIVPNRQA Mflv_2792|M.gilvum_PYR-GCK AAFTRTG---AGGVAQVDTEGLIAAVFTHRDSRAGDPDLHTHVAISNKVS Mvan_3254|M.vanbaalenii_PYR-1 AAFTRTG---TNGVAQVDTEGLIAAVFTHRDSRAGDPDLHTHVAIANKVS Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M RADG----QLVSIDGTSLYHEAKAAGVIYQATLRRELHQSLGFEWLPVDP Mflv_2792|M.gilvum_PYR-GCK YVDANGVRRWLALDGQPLHRVTVAASELYNTRLEAHLIARLGVRFAEQSR Mvan_3254|M.vanbaalenii_PYR-1 YLDQNGVRRWLALDGQPLHRVIVAASEMYNTRMEVHTIDRLGVDFAEASR Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M ATG---MAEVAGIAPESVTAWSQRSSQLREWAAGNLALADGQNLSP---- Mflv_2792|M.gilvum_PYR-GCK GRGKRPVREIVGMSARLMERWSSRRAAIKARTAELAKQFQADHGREPTNV Mvan_3254|M.vanbaalenii_PYR-1 GRGKRPVREIVGMSVELMMRWSSRGIAIKARTAELAKQFQHDHGREPTTI Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M ---AQLSAAQKATRPAKPEQLSFAELRAAWRADERGVRLDD--------- Mflv_2792|M.gilvum_PYR-GCK EIIALAQHATLESREAKHEPRSLGEQRQEWRTQAVEVLGERGVNQMLSDT Mvan_3254|M.vanbaalenii_PYR-1 ESLALAQQATLESREAKHEPRSFAEQRATWRNQAIEVLGHDGLNRMLATV Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M ------------------AARRAARQARREGSRQPFDRRRLAAAAEQIDK Mflv_2792|M.gilvum_PYR-GCK LAAPQTTREAVTIDEEWFASRAGELIATVAESRSTWQRHHVRAEALRMAR Mvan_3254|M.vanbaalenii_PYR-1 LAP-RRAQKTPEITAEWVASRAVALVATVAETRATWQAHHVRAEALRMVR Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M AGFTRADLVEIVGAQLPVDTEQSPRRLVEAAVEEIGILLTAARQP----H Mflv_2792|M.gilvum_PYR-GCK GHDVAHDVALVERLTDTALGEGFSVPHARVEDAELGEPVALRRRDGASVY Mvan_3254|M.vanbaalenii_PYR-1 AEGVAHVAGLVERLTDTALSEAFSVPHARVEDGELGEPVALRRRDGSSVY Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M QREGHDRFTLDRILAEEAALLQLVD--------AQDIRAELWVKERDTEG Mflv_2792|M.gilvum_PYR-GCK RRHGVALYTSQETLAAEQRILDAVHRGDGRVASAADVEMALADSTARGRT Mvan_3254|M.vanbaalenii_PYR-1 SRHGVATYTSRDVLAAEERILAAVARRDGRMATASEVDLALSDSAARGKP Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M LSPDQKRVVENIATSPWLVQPLSAPAGAGKTTSLRALATMARRRHTARVF Mflv_2792|M.gilvum_PYR-GCK LNPGQAALVTEMATAGRRVALALAPAGTGKTTAMAALAHAWRS-SGGHVI Mvan_3254|M.vanbaalenii_PYR-1 LNLGQAALVEQMATSGRRVALALAPAGAGKTTAMAALAHAWRS-SGGHVL Rv2311|M.tuberculosis_H37Rv -MAPTGQAVDVAVREGAGDVGYSVE------------------------- Mb2338|M.bovis_AF2122/97 -MAPTGQAVDVAVREGAGDVGYSVE------------------------- MMAR_3605|M.marinum_M VLAPTGTAVDVAIREGAGDVGYTIAKALHELDKG----------TLTLGH Mflv_2792|M.gilvum_PYR-GCK GLAPT-ADAAIVLGEDLGATTDTLDKYVWSADPAKAATSHVPDWFSRVGP Mvan_3254|M.vanbaalenii_PYR-1 GLAPT-AAAAIVLGEDLGATTDTLDKYVHCADPDNAATFGTPQWFTDIGP :*** . :.: *. * . :: Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M LDLVVVDEAAMVGTDDLRRLLAATTTARTKTVLVGDAHQLAPVKARGGMF Mflv_2792|M.gilvum_PYR-GCK DTLIVVDEAGKAATAGLDAMIRDALKKGASVRLVGDDGQLSSISAGG--I Mvan_3254|M.vanbaalenii_PYR-1 DTLIIVDEAGMASTAGLDAMIADAQRKGASVRLVADDCQLASISAGG--V Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M AQLCADLPWAQQLSEVWRMRDPEERTASLALRDGGPAPVRRAVEWYRTHD Mflv_2792|M.gilvum_PYR-GCK LRDIAEATDALTLSEVVRFKSPAEAAAGLALHDADPAGIG----FYIDHH Mvan_3254|M.vanbaalenii_PYR-1 LRDIATETGALTLSEVVRFHSRAEAAASLALRGGDPAGIG----FYIDSG Rv2311|M.tuberculosis_H37Rv ----------------------------------------------RENL Mb2338|M.bovis_AF2122/97 ----------------------------------------------RENL MMAR_3605|M.marinum_M RLHTGDAITMAADALAAYNRDTAAGRNALLICDTTEMADALNRRIHRDII Mflv_2792|M.gilvum_PYR-GCK RIHVGTDETAADMAYQAWRADLAAGGDSILLAPTNDVINELNARARIDRL Mvan_3254|M.vanbaalenii_PYR-1 RIHVGTEQTAADTAFSAWLADRNAGRDSLLLGPTNAIVDDLNARARTARI : Rv2311|M.tuberculosis_H37Rv PAD-----------------------------------------DPVRNG Mb2338|M.bovis_AF2122/97 PAD-----------------------------------------DPVRNG MMAR_3605|M.marinum_M AADQPAVIAARGHRIAVGDLIISRRNDPTLPVFDATDIK--KGADPVRNG Mflv_2792|M.gilvum_PYR-GCK AADPEAAK----SPTVVLAEQLHASVGDTIRTRKNNRRIGIGRNDFVRNG Mvan_3254|M.vanbaalenii_PYR-1 AAHVEADPNWRPGRETVLADQLRASVGDVIRTRHNARWLPLSGTDYVRNG .*. * **** Rv2311|M.tuberculosis_H37Rv NRWRVIAVDTEHHRIAARRLGDGARAAFSGDYLHEHITHGYAITVHASQG Mb2338|M.bovis_AF2122/97 NRWRVIAVDTEHHRIAARRLGDGARAAFSGDYLHEHITHGYAITVHASQG MMAR_3605|M.marinum_M NRWRIYAVDPGNNRVAARRLHDGARAAFTGDYLREHITYGYAITVHSAQG Mflv_2792|M.gilvum_PYR-GCK YRYTITEVLADG-GVKARHLRSGRIVTLPADYIAEHVTLGYAATIDSAQG Mvan_3254|M.vanbaalenii_PYR-1 YTFDILDVARDG-ALRARHSGTGHEITLPADYVTEHVTLGYASTINGAQG : : * : **: * ::..**: **:* *** *:..:** Rv2311|M.tuberculosis_H37Rv TTAH------STHAVLGDNTSRATLYVAMTPARESNTAYLCERTAGEG-- Mb2338|M.bovis_AF2122/97 TTAH------STHAVLGDNTSRATLYVAMTPARESNTAYLCERTAGEG-- MMAR_3605|M.marinum_M VTAD------TTHAVLGENTTRALLYVAMTRGRSANTAYLHERIAGENEH Mflv_2792|M.gilvum_PYR-GCK LTSGSRDTRGTCHIVGSDMLTRQHLYVALTRGTDENHLYLSTAEGDPHRL Mvan_3254|M.vanbaalenii_PYR-1 STAG-----YSCHVVGAEHLTRQQLYVALTRGRAENHLYLSTAETDPHRI *: : * * .: :* ****:* . * ** . Rv2311|M.tuberculosis_H37Rv -----------------------------ARVDLAGWDLWVSGKAEAMSD Mb2338|M.bovis_AF2122/97 -----------------------------ARVDLAGWDLWVSGKAEAMSD MMAR_3605|M.marinum_M RQPNGVHIPRRGTAKE---------AAQRARTIIANQDEQAR-TADQIAQ Mflv_2792|M.gilvum_PYR-GCK LSPKATHPDTAVDVLTRILARNGAQVSATTAARQAADPAARLQAAADMYY Mvan_3254|M.vanbaalenii_PYR-1 LAPKATHPDTAVDVLSRIVARGGGQVSATTTARQAADPTRRLAAAADMFT : . * * : Rv2311|M.tuberculosis_H37Rv EKSASPVWCRVGARCDHRG---KRSCW----------------------- Mb2338|M.bovis_AF2122/97 EKSASPVWCRVGARCDHRG---KRSCW----------------------- MMAR_3605|M.marinum_M DADASALPERVRSLLRRRSDAIRQRCTTYQQWRNAVAGMNITDGYTLGQH Mflv_2792|M.gilvum_PYR-GCK DALGAAAENRLGVGARDRLDAIADEVIPQLSQREAWPVLRRNLSVLALRG Mvan_3254|M.vanbaalenii_PYR-1 DALGAAAEHQLGAGARDRLDAIAESVHTDLSTCAAWPVLRRRLAVRALSG : .:. :: * Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M IDRSRGQYVGYQAGL----------------------------------- Mflv_2792|M.gilvum_PYR-GCK ADPRELLTEALAKGSVSDAADPAAVLDHRIDPAGTHSSGIGVLRWLPAVP Mvan_3254|M.vanbaalenii_PYR-1 ADPGELLAAAHARGGLDDAADAAAVLDYRIDPTGSAGRDCGPLRWLPAIP Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK EALAEDPQWGAYLARREKLVEDLAGEIRERARGWTNATAPAWARPLITVN Mvan_3254|M.vanbaalenii_PYR-1 DRLAGDPQWGDYLRRRGQLVSDLADQIREQARAWTPDTAPSWAQPLVTAN Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK PVLTAESAVFRAATGVAEADTRITGARQFPVRSRGVQAALQRQAAADIGR Mvan_3254|M.vanbaalenii_PYR-1 PALAAEIAVFRAATGVDGADTRLTGPAQYPVATRAIQDLLQRHGTDAIER Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK HSADTSRWNDVIDGIDPRLRSDAYWPQLADQLVKAARITPQLRQIITTAA Mvan_3254|M.vanbaalenii_PYR-1 NSADPTRFNDLLDQIDPRIRADAYWPTLAAHLTNAARGN-DISDAITAAA Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK RQGPLPDELPAAALWWRISGALSPTATLATTHSRLRPPWVTDIDVVFGTS Mvan_3254|M.vanbaalenii_PYR-1 QRGPLPDEMPAAALWWRLADALSRTAAIPDRT-------VVDHATAQGDG Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK LAETITSDPAWPGLVAAIGAADPRKWTPRDLLHVAAEQLADATDGDHPIP Mvan_3254|M.vanbaalenii_PYR-1 LHASIAAERALVEVLAAS-------WRNADPLPLARPR------------ Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK PGDYARLITYTVDAFTHRLQARLGVDFQDLPAPEDTPIDPAEEALFPPDP Mvan_3254|M.vanbaalenii_PYR-1 -------------------------------------TDPAAVALSLP-- Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK QDPSAHVEEHSPFDDSVDLAPPEEIDSFEYGSEGYAGLRFEDLSANRPTP Mvan_3254|M.vanbaalenii_PYR-1 -------------------------------------YVVATVAAERYTP Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK ELGITMDAFIALRAEYRNVCDEIKTLAADIRAGNGPALRAAAGDLLRMRH Mvan_3254|M.vanbaalenii_PYR-1 EL-----------------AEAIHTAATDANR------------------ Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK QVDADRPYSHAITDVMEQWSDADRAYNDTLRLIEHSRSQLDLLLATPDAE Mvan_3254|M.vanbaalenii_PYR-1 ---------------------------------HHVR-----ITATPQPD Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK ELDIISARQQIAFYTDMLPEQPPSLQFQQALADAQAARAAAAGGGGGGDK Mvan_3254|M.vanbaalenii_PYR-1 RLSLNHLAEQITIH------------------------------------ Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK IVTERDIAAARGAAERTDIAALNVLRVRRPVLRRELERAERDIATAFAAA Mvan_3254|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK QTSTSDTLEQLLESARSEVALLRVSGHLDPERTPLRIPDAALSGLEPQTA Mvan_3254|M.vanbaalenii_PYR-1 ----------------------------EPTRR----------------- Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK DRLKSVAAQPYRLAVIRADITDSETAAALYTLRNAANAEDRKVLWLSPTE Mvan_3254|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK ASLTPAHDAELADTITTIRHAHQQVSEQQWALSAGAIVVIEDPAAAEPDQ Mvan_3254|M.vanbaalenii_PYR-1 ----------------------------------GPVIVVEDAAAADPDA Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK LVGLARHAADADARLVLLDPGTSRGPSSSAVQLLTNSLPWNNALTTTPST Mvan_3254|M.vanbaalenii_PYR-1 LAAVATALVPAHGRLLLVDN----GQLGSARRLLDG-LTLPWAENTRPAA Rv2311|M.tuberculosis_H37Rv -------------------------------------------------- Mb2338|M.bovis_AF2122/97 -------------------------------------------------- MMAR_3605|M.marinum_M -------------------------------------------------- Mflv_2792|M.gilvum_PYR-GCK PEDPLLASTPAVTLADRLGRKRLSEPWQQLLTHYDIAARAIRSAQRRQLA Mvan_3254|M.vanbaalenii_PYR-1 GID----NPRLAAAAD---------------EHRAIAARSWRTLTTG--- Rv2311|M.tuberculosis_H37Rv ------------------------ Mb2338|M.bovis_AF2122/97 ------------------------ MMAR_3605|M.marinum_M ------------------------ Mflv_2792|M.gilvum_PYR-GCK RGWHTTDLAPSKDRDRTLGAGIDD Mvan_3254|M.vanbaalenii_PYR-1 ---PTRDRG--RDRDRGHGLDID-