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AGHGGGRGRCRRAAARRMHPSRRQPAGQAGVAGRTDHHTAGRGPAQPEGGRRRGEPVRGRRAGTLCRPGA GGRPAVARRPPPARLRRRPLDRRGRRVLHRGDGRGLPGRVRPGGRTGHGAADRRRMPRHHAECHHDAGPH LRVRRAARGGRRPRRQRALVAARDRLELRQPVRRRPQRRDRDHHLRTRARLRRGVAGRGGTGADRRAGQH RRVISPATRRGRCP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3199 | - | - | 100% (225) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1363 | - | 3e-08 | 32.48% (234) | LigA |
| M. vanbaalenii PYR-1 | Mvan_5774 | - | 3e-06 | 32.64% (144) | HNH endonuclease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1485 | - | 4e-07 | 32.17% (230) | hypothetical protein Mflv_1485 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_5011 | - | 8e-06 | 30.88% (204) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_5152 | - | 7e-12 | 33.64% (214) | hypothetical protein MSMEG_5152 |
| M. thermoresistible (build 8) | TH_2635 | - | 3e-05 | 39.24% (79) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3199|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1485|M.gilvum_PYR-GCK ------------------------------------------------MS
MSMEG_5152|M.smegmatis_MC2_155 --------------------------------------------------
MAV_5011|M.avium_104 -----------------------------------------MGALRVIRR
TH_2635|M.thermoresistible__bu VVTGRLHEAAKIAPPPERSWVGADLWRLLPYLMPYRARWTAMITVAVVSL
Mvan_3199|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1485|M.gilvum_PYR-GCK VGGCRACAGTSEYQTVRLRFCG-------DSTFGGPRARTDARRGVRRAG
MSMEG_5152|M.smegmatis_MC2_155 -----------------MSNTS-------NSIRSSPDVQSIDWENDEIHL
MAV_5011|M.avium_104 RSWQGLTLLVAAMVLTSCGWKG-------ISNVSIPGGPGSGPNSYNIYV
TH_2635|M.thermoresistible__bu SATVAIPLMTKAVIDGPVRQQDQQGLWILGSAAMAVGISEAVLMFIRRWL
Mvan_3199|M.vanbaalenii_PYR-1 -----MAGHGGGRG--------------------------RCRRAAARR-
Mflv_1485|M.gilvum_PYR-GCK RLRFCLRAAGGGRAGGSRRVQEAALAQIGARRHRDADDRLRVRPVASRRG
MSMEG_5152|M.smegmatis_MC2_155 ESHFHRHDRGSGRS--------------------------PGRGGPERR-
MAV_5011|M.avium_104 QVPDTLAINGNSKVMVADVFVGSIKAIQLKNWIATLTLGINKNVKLPKN-
TH_2635|M.thermoresistible__bu VARATMGVEADIRKDLYARLQILPMSFHGRWQSGQLVSRVMNDLSTIRRL
.. : :.
Mvan_3199|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1485|M.gilvum_PYR-GCK RGPGRFGARRLRTSRRRHRGYRRDRGDRRTSGSESGIGTGRSTRGRRPRP
MSMEG_5152|M.smegmatis_MC2_155 --------------------------------------------------
MAV_5011|M.avium_104 --------------ATAKIGQTSLLGSQHVELAAPPNPSPELLKDGDTIP
TH_2635|M.thermoresistible__bu LSFGLVFLVLNGLQIAVVTSILLAMYWPLGVVALLSIVPITMTVLHFQRL
Mvan_3199|M.vanbaalenii_PYR-1 MHPSRRQPAGQAGVAGRTDHHTAGRGPAQPEGGRR-----RGEPVRGRR-
Mflv_1485|M.gilvum_PYR-GCK HHAHRRPGAGRSRTDDRRALHPAASARQVAGAGRG-----RVGGIADRRR
MSMEG_5152|M.smegmatis_MC2_155 --GERRAGPG----SARADAEPAGGQPTRRRAGR------RAAAAAGRR-
MAV_5011|M.avium_104 LKNSSSYPTTEQTLASLSLILRGGGIPNLEVLQNE-----VYNIFNGRGE
TH_2635|M.thermoresistible__bu YTRLSRQAQDETGHVATHVEEAALGVRVVKSFGRERYSYDRFDEQATRLF
. . *
Mvan_3199|M.vanbaalenii_PYR-1 ------------AGTLCR----------------PGAGGRP---------
Mflv_1485|M.gilvum_PYR-GCK CRPHRDHETRSAAASLTRRAA-------------PGAAGPPDRRRAAGAG
MSMEG_5152|M.smegmatis_MC2_155 ---------------LRAHRN-------------PGAGSRA---------
MAV_5011|M.avium_104 AIRALLGKLDTFTNQLNQQRDDITHAIDSTNRLLTYVGGRADVVDRLLTD
TH_2635|M.thermoresistible__bu RTQVGRVEVSARFWTLLEIIPNLTLIVVLGFGAYAAGTGLVTMGTLVAFI
* . .
Mvan_3199|M.vanbaalenii_PYR-1 --------------------------------------AVARRPPPARLR
Mflv_1485|M.gilvum_PYR-GCK LHRVGEPSAGPQRPRTDQRPDFRRVPRTRTTDRSAPHTAAAAGSPDADLH
MSMEG_5152|M.smegmatis_MC2_155 -------------------------------------AADRAGNPDPAAG
MAV_5011|M.avium_104 VPPLIKHFADTKQLLINAVDSVG-----RLSQAADQYLSEARGPLHTDLQ
TH_2635|M.thermoresistible__bu TMMLSLVWPIASLGFLLSMTQESMTAANRIAEIFDAPIEITDGPITTPPR
.
Mvan_3199|M.vanbaalenii_PYR-1 R---------RPLDRRGR--------------------------------
Mflv_1485|M.gilvum_PYR-GCK RPRHPPDADGRPVPQRVRGRLCARWDAGRAGSVHRQRV------------
MSMEG_5152|M.smegmatis_MC2_155 AG------------------------------------------------
MAV_5011|M.avium_104 ALQCPLKELGKASPYLIGALKLILTQPFDIDTVPKIFRG-----------
TH_2635|M.thermoresistible__bu RGRLELRDVGFKFPDSGGVGASGGQDTWVLRHVTVTVEPGETLALVGPTG
Mvan_3199|M.vanbaalenii_PYR-1 ---------------------------------RVLHRGDGRGLPGRVRP
Mflv_1485|M.gilvum_PYR-GCK ----------------------------SAVTDQHLHRHGGQDLGDSRGP
MSMEG_5152|M.smegmatis_MC2_155 ------------------------------------HSARHGACRDRHRA
MAV_5011|M.avium_104 -----------------------DYINISLTLDLTYSAVDNAFLTGTGLS
TH_2635|M.thermoresistible__bu SGKSVLVSLLSRLYDVTEGQIRIDGIDIRELSLDALRRTVATAFEDPTLF
.
Mvan_3199|M.vanbaalenii_PYR-1 G------GRTGHGAADRRRMPRHHAECHHDAG-------------PHLRV
Mflv_1485|M.gilvum_PYR-GCK GDH-RLPGHDGRIASAVQPADHDHPGTRRSAGGVHPHDAARVLRRPRFRR
MSMEG_5152|M.smegmatis_MC2_155 R---------GHPGRQRRGLARAVGRGHHPAG-------------ARYAD
MAV_5011|M.avium_104 GALRALEQSYGRDPETMIPDVRYTPNPNDAPGGPLVERGDRNCDSLRPTP
TH_2635|M.thermoresistible__bu SVSVEENLRLGRPPANPASDAELAEAIEIAAAEFVHDLPYGLHTRIGEQG
*: . . ..
Mvan_3199|M.vanbaalenii_PYR-1 RRAARGG-----------------------------------RRPRRQRA
Mflv_1485|M.gilvum_PYR-GCK AGARRGRGAGVRHRRHLRHRSLAGRMGGPVRRPADRPGRHRFRGPRHEHP
MSMEG_5152|M.smegmatis_MC2_155 PAAADGQ------------------------------------HPRRPRF
MAV_5011|M.avium_104 TGRLRDPDRHLAARARHLLPADPELGGDRPVHAQGRAAGVGRPVPDGQRH
TH_2635|M.thermoresistible__bu MSLSGGQRQRLSLARAVLAAPTILVLDDTLSALDVHTEAVVTEALRRVLR
.
Mvan_3199|M.vanbaalenii_PYR-1 LVAARDRLELRQP--------------------------------VRRRP
Mflv_1485|M.gilvum_PYR-GCK HAGQRRRLDVRQHRHVRELGAVHGDRSAGPATVHAA-LRARGRNETALRP
MSMEG_5152|M.smegmatis_MC2_155 AGAHRLAAGRPRP---------------------------------GRHQ
MAV_5011|M.avium_104 LSRHHHRQGHRRR--------------------------------AHRAR
TH_2635|M.thermoresistible__bu DVTGIVVANRASTVLLADRVALLERVGPDGATITHVGTHAELLADVPQYR
Mvan_3199|M.vanbaalenii_PYR-1 QRRDRDHHLRTRARLRRG-VAGRGGTGADRRAG---QHRRVISPATRRGR
Mflv_1485|M.gilvum_PYR-GCK DRDDRRPRGDDAAVQRIG-AVGQGSDRHHDLPGGLPDQLLPVPPAGRAGL
MSMEG_5152|M.smegmatis_MC2_155 HRRQRGHGSRTRPHRTRG-FGPLGSRAAGAAAD----RRSAVTPELV---
MAV_5011|M.avium_104 RRGDHEHRQPLQDPDRRGGQRALGVGGRRAVPGPGVERKPGQVPVVRADH
TH_2635|M.thermoresistible__bu YLLAADPDLDDGAEPTPXXXVRAGTVATGSRSPTPTRCHPRRGSRRCRSR
* . .
Mvan_3199|M.vanbaalenii_PYR-1 CP------------------------------------------------
Mflv_1485|M.gilvum_PYR-GCK PPRCRPGPRHGAVPGHVAGPGPHRLRDVDHPAADEDGVRRRDPVPAVTFP
MSMEG_5152|M.smegmatis_MC2_155 --------------------------------------------------
MAV_5011|M.avium_104 HQGHGAGRDR-AGPGHREPRAGGAAQGEDRPVARRDGAVRRRVGPQPAAA
TH_2635|M.thermoresistible__bu PPAAPRRPPRRPTSSGCRPAPGRSRRIRHRADGRPGSSRRRSAGRRPSPS
Mvan_3199|M.vanbaalenii_PYR-1 -----------------------------------------
Mflv_1485|M.gilvum_PYR-GCK GVTS-------------------------------------
MSMEG_5152|M.smegmatis_MC2_155 -----------------------------------------
MAV_5011|M.avium_104 GRRHPGHRRRLQEPDHRRQRHHRALRAGDRQPGQIR-----
TH_2635|M.thermoresistible__bu PRDSRGSDRGVPVAYTGYMSCSSRLVPVVSTTFAPMLSVQM