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TERQVLHGGTVLTGPQWRPRPADLLIAGGRIEAVAAPGSLAGVDAATHDVTGRLVIPGLINAHTHSHTAP ARGAARAWTLEDSLLNGGWMAAPRSEELTELAALLTATELIASGCTGAFDLIAQAGGPDPAGCHAAARGY ARAGLRTVLAPMVADRTLHEAVPAIGACCGAPSTGKPGPSTADVLAACTAYVRNFPALQGVMPALAPTIP GHCTPELTVGLGRLAAEHGLRVHTHLAESKPQALAGASRFGHSITRELARLGVLGDRLTVAHAIWVDDED IRMLAASGAVAVTVPGSNLRLGSGIADTRAMLAAGLRLAVGTDGANSADAFDALDAVRLTALLSRVSERP ARQWLTVEETLDAATAGGAAACGWTDTGRLAPGRRADFALLDLGARAFRPPTDLANQLLTAARAADVTDV VVGGRFVYRDRGFPHLDVAAALNRFDTLVEEFRARVAPVRADADRQTALAATALAGLRRAPSPVRRLIGW R*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3150 | - | - | 100% (492) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_0863 | - | 3e-52 | 34.48% (464) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_3147 | - | 4e-32 | 32.11% (436) | amidohydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0136 | - | 4e-06 | 42.42% (66) | amidohydrolase 3 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2927c | - | 1e-31 | 33.25% (385) | hydroxydechloroatrazine ethylaminohydrolase |
| M. marinum M | MMAR_2844 | - | 3e-27 | 31.67% (420) | metal-dependent hydrolase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1297 | - | 2e-28 | 31.73% (353) | hydroxydechloroatrazine ethylaminohydrolase |
| M. thermoresistible (build 8) | TH_3859 | - | 3e-20 | 25.76% (462) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2914 | - | 6e-26 | 31.19% (420) | hydroxydechloroatrazine ethylaminohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2844|M.marinum_M MSTILLTLMLECRVPKLVIDRVSIATVDPKAAEFSEGHIIVEDDLIVAVG
MUL_2914|M.ulcerans_Agy99 --------MLECRVPKLVIDRISIATVDPKAAEFSEGHIIVEDDLIVAVG
MSMEG_1297|M.smegmatis_MC2_155 -------------MPRLVIDGAAIATVDAAHTEHNRGYIVVDDNIITAVG
MAB_2927c|M.abscessus_ATCC_199 ------------MNPITLIENVFAATVDKSRREIADARVVIEGGRIAAVL
Mvan_3150|M.vanbaalenii_PYR-1 ------------MTERQVLHGGTVLTGPQWRP--RPADLLIAGGRIEAVA
TH_3859|M.thermoresistible__bu -----------------------VLAGDPLTAHVRAADLLIEDGRVTAIE
Mflv_0136|M.gilvum_PYR-GCK ------------MTYDLVIRGGTVVDG--LGGEPFTADVAVTDGIIREVG
. : : .. : :
MMAR_2844|M.marinum_M DG----PAPEVPGATVIDGRGCLATPGLVNTHEH-----LYQWITRGYTQ
MUL_2914|M.ulcerans_Agy99 DG----PAPEVPGATVIDGRGCLATPGLVNTHEH-----LYQWITRGHTQ
MSMEG_1297|M.smegmatis_MC2_155 AG----PAPEVPGAQFIDARGCLATPGLVNTHHH-----LYQWITRGHAQ
MAB_2927c|M.abscessus_ATCC_199 TAGENNPWQELPGVERVDGSGCLLTPGLVNTHHH-----LYQWITRGLAA
Mvan_3150|M.vanbaalenii_PYR-1 AP----GSLAGVDAATHDVTGRLVIPGLINAHTH-----SHTAPARGAAR
TH_3859|M.thermoresistible__bu SD------LAGVDAEIIDATGRWVLPGFVDTHRH-----LWQTTMRGLTA
Mflv_0136|M.gilvum_PYR-GCK AVG-------SAGAREIDATGLLVTPGFVDLHTHYDGQAIWSDRLTPSSA
.. * * **::: * * :
MMAR_2844|M.marinum_M KGTLFQWLTEMYPVWGRLDA-ELEFAAASAGLAGLALTGCTTTMDHHYVF
MUL_2914|M.ulcerans_Agy99 KGTLFQWLTEMYPVWGRLDA-ELEFAAASAGLAGLALTGCTTTMDHHYVF
MSMEG_1297|M.smegmatis_MC2_155 DGTLFEWLTTLYPLWSHLDA-DLEYVAASAALAALALSGCTTTTDHHYVF
MAB_2927c|M.abscessus_ATCC_199 DHTLFQWLTALYPVWQGIDA-DSLHVAAQGALSWLALSGCTTTTDHHYVF
Mvan_3150|M.vanbaalenii_PYR-1 AWTLEDSLLNGGWMAAPRSE-ELTELAALLTATELIASGCTGAFDLIAQA
TH_3859|M.thermoresistible__bu NWNLKDYFWCIRSHFAGLHDPDDVYGGQYAGGLDALVNGVTTTIDHSHIT
Mflv_0136|M.gilvum_PYR-GCK HGVTTAVMGNCGVGFAPCRPADHDVLVDVMAGVEDIPG--VVMVDGLPWQ
: : . *
MMAR_2844|M.marinum_M PHAGGDMLGAEIAAAKRIGVRFHPTRGSMD---------LGVASGGLPPE
MUL_2914|M.ulcerans_Agy99 PHAGGDMLGAEIVAAKRIGVRFHPTRGSMD---------LGVASGGLPPE
MSMEG_1297|M.smegmatis_MC2_155 PRGGGDVLGAEIAAAQRIGLRFHPTRGSMD---------LGASAGGLPPD
MAB_2927c|M.abscessus_ATCC_199 PSDAGDLLEAEIEAARQVGLRFDPTRGSMD---------LGRSAGGLPPD
Mvan_3150|M.vanbaalenii_PYR-1 GGPDPAGCHAAARGYARAGLRTVLAPMVADRTLHEAVPAIGACCGAPSTG
TH_3859|M.thermoresistible__bu NSP--DHSDAAVRGLLDSGVRALWCYGFYP----------------SPQA
Mflv_0136|M.gilvum_PYR-GCK WETFPEFLDAVASRQRDIDVAAFLPHSPLR---------VYVMGRRGVDR
* .:
MMAR_2844|M.marinum_M HTVEDIDTILTTCQDAVREHHDPTKGSMVQISLAPCSPFSVTGELMKQSA
MUL_2914|M.ulcerans_Agy99 HTVEDIDTILTTCQDAVREHHDPTKGSMVQISLAPCSPFSVTGELMKQSA
MSMEG_1297|M.smegmatis_MC2_155 NVVEDIDAILAAGQDAVGAHHDPSFGSMCRIALAPCSPFSVSGELMRESA
MAB_2927c|M.abscessus_ATCC_199 GLVESIDTALEASDAAIARWHDPAPGAMVRIGLAPCSPFSVSADLLRQSA
Mvan_3150|M.vanbaalenii_PYR-1 KPGPSTADVLAACTAYVRNFPALQG---VMPALAPTIPGHCTPELTVGLG
TH_3859|M.thermoresistible__bu DPVFTTPQHRLDDARRVRSTFFPTDDGLVRMGVALTELGMQPFTETQREL
Mflv_0136|M.gilvum_PYR-GCK EPATDEDLEMMRKLAAEAVHAGALGFASSRFTLHKTESGQPIPSYNADYA
:
MMAR_2844|M.marinum_M LLARDLGVRLHTHLSETVEEDEFCLAQFGSRPVDYVESLGWLGSDVWMAH
MUL_2914|M.ulcerans_Agy99 LLARDLGVRLHTHLSETVEEDEFCLAQFGSRPVDYVESLGWLGSDVWMAH
MSMEG_1297|M.smegmatis_MC2_155 ALARELGVRLHTHIAETTDEEQFCLERFGARPVDYVESLGWLGDDVWFAH
MAB_2927c|M.abscessus_ATCC_199 LLARERGVRLHTHLAETKDESVYCAERFGCSPLDYMEELGWLGPDVWFAH
Mvan_3150|M.vanbaalenii_PYR-1 RLAAEHGLRVHTHLAESKPQALAGASRFGHSITRELARLGVLGDRLTVAH
TH_3859|M.thermoresistible__bu QTAEDLAVPVTMHTN-------CVWTRPEFHDVELYHRAGLLRAGQIHSH
Mflv_0136|M.gilvum_PYR-GCK EIEAIARGVQDGGGGLIQFVPDLVAGDYEPVLQTVFDAAADVGLPVTFTL
. : :
MMAR_2844|M.marinum_M CVHLSKG-----DIAKLAATGTGVAHCPTSNGRFGAGIAPIPELLAADVA
MUL_2914|M.ulcerans_Agy99 CVHLSKG-----YIAKLAATGTGVAHCPTSNGRFGAGIAPIPELLAADVA
MSMEG_1297|M.smegmatis_MC2_155 GVHLSAS-----DIAKLAQTGTGVAHCPSSNARLGAGTAPIPELLAAGVP
MAB_2927c|M.abscessus_ATCC_199 GVHFDDA-----SIARLARTGTGIAHCPTSNGRLGAGIARVRELLAAGVP
Mvan_3150|M.vanbaalenii_PYR-1 AIWVDDE-----DIRMLAASGAVAVTVPGSNLRLGSGIADTRAMLAAGLR
TH_3859|M.thermoresistible__bu ANRCSDH-----ELALLRDAGCAVSSTPDTELQMGCGRPVFRRALATGVT
Mflv_0136|M.gilvum_PYR-GCK AVGNAGDPFFLDALTMVEKANANGGDITAQIFPRPIGLVLGLELSGNPFV
: : :. . * . .
MMAR_2844|M.marinum_M VGLGVDGAG-AEHRGLANEMRQAALAAR-FRLGPQ---------------
MUL_2914|M.ulcerans_Agy99 VGLGVDGAG-AEHRGLANEMRQAALAAR-FRLGPQ---------------
MSMEG_1297|M.smegmatis_MC2_155 VGMGVDGVASNEHGGLGGELRQALLMAR-NRLGPT---------------
MAB_2927c|M.abscessus_ATCC_199 VGLGVDGAASNESGRLLEEAHQALLLAR-AVGGPT---------------
Mvan_3150|M.vanbaalenii_PYR-1 LAVGTDGANSADAFDALDAVRLTALLSR-VSERPARQ-------------
TH_3859|M.thermoresistible__bu AGIGIDIVS-NNSGDMFTAMRVLMQHERGDALQPTLEESGLTAVAEPL--
Mflv_0136|M.gilvum_PYR-GCK MYPSYREIAALPLAERVAEMRKPEVRERILNDTPASDGHPLMFAAQAWNY
. : * *
MMAR_2844|M.marinum_M --ALDAREALWMATVGGARCLGRDQDLGSLEVGKL------------ADI
MUL_2914|M.ulcerans_Agy99 --ALDAREALWMATVGGARCLGRDQDLGSLEVGKL------------ADI
MSMEG_1297|M.smegmatis_MC2_155 --AITARQVLQAGTIGGARCLGRDRELGSLEPGKL------------ADM
MAB_2927c|M.abscessus_ATCC_199 --ALSTRTALELATLGGARLLGRSDEIGSIEVGKC------------ADL
Mvan_3150|M.vanbaalenii_PYR-1 --WLTVEETLDAATAGGAAACGWT-DTGRLAPGRR------------ADF
TH_3859|M.thermoresistible__bu --PVTTRQILHAATLAGARALGLESVCGSIDVGKS------------ADL
Mflv_0136|M.gilvum_PYR-GCK MFPLTDPPNYEPSPSDSIGARARARGVSPLEEAYDRLLDDDGHAMLLVTL
: .. . . . : . . :
MMAR_2844|M.marinum_M ALWQLDGLGHSDVEDPVWALIYGP-PAPLRLLLVGGNTVVE---------
MUL_2914|M.ulcerans_Agy99 ALWQLDGLGHSDVEDPVWALIYGP-PAPLRLLLVGGNTVVE---------
MSMEG_1297|M.smegmatis_MC2_155 ALWRVDGLGHADIDDPVCALVFGP-SAPLRLLLVNGVPVVA---------
MAB_2927c|M.abscessus_ATCC_199 VLWDLSTLGHSGIEDPVAAVILGE-VPPIRRSWVGGRPIVA---------
Mvan_3150|M.vanbaalenii_PYR-1 ALLDLGARAFRPPTDLANQLLTAARAADVTDVVVGGRFVYR---------
TH_3859|M.thermoresistible__bu LLLRHDRLHMRPVIDDIDSIVLQATTRDIDRVLVAGRTVVQ---------
Mflv_0136|M.gilvum_PYR-GCK ANFRDGTLDTVAELIRRDDVVLGLGDGGAHYGMICDASFPTYMLTHWVRD
. :: : . .
MMAR_2844|M.marinum_M --DGELRTADTETLATDAKNAAVTLRERG---------------------
MUL_2914|M.ulcerans_Agy99 --DGELRTADTETLATDAKNAAVTLRERG---------------------
MSMEG_1297|M.smegmatis_MC2_155 --DDELRTADTATLAGDARDAARTLRARAGT-------------------
MAB_2927c|M.abscessus_ATCC_199 --DGQMLTVDTERIAVAVRAAHHGLMNRER--------------------
Mvan_3150|M.vanbaalenii_PYR-1 --DRGFPHLDVAAALNRFDTLVEEFRARVAPVRADADRQTALAATALAGL
TH_3859|M.thermoresistible__bu --DGRLPAAVERRGVAAIEAAHSRLAERVAAVGGWKLAVPQGLMDQLGVT
Mflv_0136|M.gilvum_PYR-GCK RPSGRLTVPEAVRELTSVPARVAGLGDRGRIAVGYKADLNVIDADTLRLH
. : : *
MMAR_2844|M.marinum_M --------------------------------------------------
MUL_2914|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1297|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2927c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_3150|M.vanbaalenii_PYR-1 RRAPSPVRRLIGWR------------------------------------
TH_3859|M.thermoresistible__bu FHDNVANTPAQANS------------------------------------
Mflv_0136|M.gilvum_PYR-GCK RPVIVKDLPGGGRRLDQTADGYVATIVSGEVIAENGEPTDARPGALIRGR
MMAR_2844|M.marinum_M ------
MUL_2914|M.ulcerans_Agy99 ------
MSMEG_1297|M.smegmatis_MC2_155 ------
MAB_2927c|M.abscessus_ATCC_199 ------
Mvan_3150|M.vanbaalenii_PYR-1 ------
TH_3859|M.thermoresistible__bu ------
Mflv_0136|M.gilvum_PYR-GCK RPAPVA