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PVITARSRPPALLLLPAALVAAGTLIPLVYLVERALGRGWPFVVDELLQPRTAALVGRSLLLVAVVTAAC VVLGVGLAVLVTRTNLRGRRALAVSLTLPLAMPSYLLAYLWVSAYPTITGFWGAALVLTLVSYPLVLLTT MAALARVDPAQEEVARSLGLGGVAVLFRVTLRQARPAIAAGALLVALYVLSDFGAVAAMRFEAFTWVIYG AYRSGFNPSRAAVLSLVLMVFAVALVVAEHRARGRAAASRIGGGSPRPAPLNRLGPWSPLALLVPAAVLA AAVAVPTVELAGWLLTAGPRWDVAEWLDALGSTVWLSAAAAVVSTAAALPLGVLAARHRDRATRTLEGAS YVAHGLPAIVIAISMVSLGVLLLRPIYQREPLLILAYTVLFVPMAIGSIRAAVEAAPIRLEEVARSLGRP PVRAFGAVTARVALPGIAAGAALVLLTCMKELPVTLLLHPTGTDTLATRLWGYSSVSDYAAAAPYAAALL LFAAVPTAVLGMWGTDDAGVRSD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3092 | - | - | 100% (514) | binding-protein-dependent transport systems inner membrane component |
| M. vanbaalenii PYR-1 | Mvan_6022 | - | 3e-35 | 25.70% (533) | binding-protein-dependent transport systems inner membrane |
| M. vanbaalenii PYR-1 | Mvan_2537 | - | 1e-14 | 27.67% (253) | NifC-like ABC-type porter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2420c | cysW | 1e-14 | 25.82% (244) | sulfate-transport integral membrane protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_3362 | - | 0.0 | 86.96% (506) | binding-protein-dependent transport systems inner membrane |
| M. tuberculosis H37Rv | Rv2398c | cysW | 1e-13 | 25.21% (234) | sulfate-transport integral membrane protein ABC transporter |
| M. leprae Br4923 | MLBr_02093 | pstA1 | 4e-06 | 26.35% (148) | membrane-bound component of phosphate transport |
| M. abscessus ATCC 19977 | MAB_2434 | - | 6e-17 | 30.42% (263) | molybdenum ABC transporter permease |
| M. marinum M | MMAR_3716 | cysW | 8e-14 | 26.36% (258) | sulfate-transport integral membrane protein ABC transporter |
| M. avium 104 | MAV_2861 | modB | 4e-14 | 28.74% (247) | molybdate ABC transporter, permease protein |
| M. smegmatis MC2 155 | MSMEG_3635 | - | 0.0 | 79.28% (502) | iron(III)-transport system permease protein SfuB |
| M. thermoresistible (build 8) | TH_0284 | - | 1e-111 | 81.35% (252) | iron(III)-transport system permease protein SfuB |
| M. ulcerans Agy99 | MUL_3659 | cysW | 4e-14 | 26.36% (258) | sulfate-transport integral membrane protein ABC transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2420c|M.bovis_AF2122/97 -------------------------MTSLPAARYLVRSVALGYVFVLLIV
Rv2398c|M.tuberculosis_H37Rv -------------------------MTSLPAARYLVRSVALGYVFVLLIV
MMAR_3716|M.marinum_M -------------------------MTSSPLVRYLLRAIALTYVFALLVV
MUL_3659|M.ulcerans_Agy99 -------------------------MTSSPLVRYLLRAIALTYVFALLVV
MAB_2434|M.abscessus_ATCC_1997 ----------------------MTPAPGLPRWVYVPAAIGAALIVLPLLA
MAV_2861|M.avium_104 --------------------------------MYLPAAAGTMFVVLPLLA
Mvan_3092|M.vanbaalenii_PYR-1 -------------------MPVITARSRPPALLLLPAALVAAGTLIPLVY
Mflv_3362|M.gilvum_PYR-GCK ----------------------MSRLGRPPAGLLLPAALVAACTLVPLVY
MSMEG_3635|M.smegmatis_MC2_155 -------------------------------MLVAAGAAVVLATLVPLVY
TH_0284|M.thermoresistible__bu ------------------VLLAARPRRRTPILLLMPAAAVVTATLLPLVY
MLBr_02093|M.leprae_Br4923 MNLDTLDRPVKAVVLRPISVRRRIKNNVATMFFFTSFLIALVPLVWLLSV
. *
Mb2420c|M.bovis_AF2122/97 PVALILWRTFEPGFGQFYAWISTPAAIS-----ALNLSLLVVAIVVPLNV
Rv2398c|M.tuberculosis_H37Rv PVALILWRTFEPGFGQFYAWISTPAAIS-----ALNLSLLVVAIVVPLNV
MMAR_3716|M.marinum_M PVGVILWRTFEPGLGQFYDWISTPAAIS-----ALHLSLLLVAIVVPLNV
MUL_3659|M.ulcerans_Agy99 PVGVILWRTFEPGLGQFYDWISTPAAIS-----ALHLSLLLVAIVVPLEV
MAB_2434|M.abscessus_ATCC_1997 LVVKADWG-------QFPALVTSPASQA-----ALLLSVRTCLASTALCL
MAV_2861|M.avium_104 IAVKVDWP-------HFWSLITSPSSRT-----ALLLSLRTAAASTALCV
Mvan_3092|M.vanbaalenii_PYR-1 LVERALGR----GWPFVVDELLQPRTAA-----LVGRSLLLVAVVTAACV
Mflv_3362|M.gilvum_PYR-GCK LFERAFER----GLPFVVDELLQPRTAA-----MVGRSLLLVSVVTAACV
MSMEG_3635|M.smegmatis_MC2_155 LGERAAER----GWAFVFDELFQPRTAA-----LVGRSLALVALVTAACV
TH_0284|M.thermoresistible__bu LVQRALER----GWAFVLHELAQPRTAA-----LIGRSLLLVVVVTAACV
MLBr_02093|M.leprae_Br4923 VVARGFYAVTRFDWWTHSLRGVMPEEFAGGVYHALYGSLVQAVVAAIMAV
* : : *: . :
Mb2420c|M.bovis_AF2122/97 IFG-VTTALVLARNRFRGKGVLQAIIDLPFAVSPVIVGVSLILLWGSAGA
Rv2398c|M.tuberculosis_H37Rv IFG-VTTALVLARNRFRGKGVLQAIIDLPFAVSPVIVGVSLILLWGSAGA
MMAR_3716|M.marinum_M IFG-ILTALLLARNRFRGKGVLQAIIDLPFAVSPVIVGTALILLWGSAGA
MUL_3659|M.ulcerans_Agy99 IFG-IPTALLLARNRFRGKGVLQAIIDLPFAVSPVIVGTALILLWGSAGA
MAB_2434|M.abscessus_ATCC_1997 LFG-VPLAVVLARGPGRMTRLLRPMILLPLVLPPVVGGIALLYAFGKLGL
MAV_2861|M.avium_104 ALG-VPMALVLARGGTRLVRSLRPLILLPLVLPPVVGGIALLYAFGRLGL
Mvan_3092|M.vanbaalenii_PYR-1 VLG-VGLAVLVTRTNLRGRRALAVSLTLPLAMPSYLLAYLWVSAYP----
Mflv_3362|M.gilvum_PYR-GCK VLG-VGLAVLVTRTDLRGRRVLAVALTLPLAMPSYLLAYLWVSAFP----
MSMEG_3635|M.smegmatis_MC2_155 VLG-VGLAVLVSRTDLRGRRVLAVVLTLPLAMPSYLLAYLWVSAYP----
TH_0284|M.thermoresistible__bu VLG-VGFAVLVNRTDLVARRVLAVALTLPLAIPSYLLAFLWVSLVP----
MLBr_02093|M.leprae_Br4923 PLGSMTAVYLVEYGSGPFVRVTTFMVDVLAGVPSIVAALFIFCLWIATLG
:* : . :: : : :.. : . .
Mb2420c|M.bovis_AF2122/97 LGFVEQDLGFKIIFGLPGIVLASMFVTCPFVVREVEPVLHELGTDQEQAA
Rv2398c|M.tuberculosis_H37Rv LGFVEQDLGFKIIFGLPGIVLGSMFVTCPFVVREVEPVLHELGTDQEQAA
MMAR_3716|M.marinum_M LGFVERDLGIRIIFGLPGMVLASIFVTLPFVVREVEPVLHELGTDQEQAA
MUL_3659|M.ulcerans_Agy99 LDFVERDLGIRIIFGLPGMVLASIFVTLPFVVREVEPVLHELGTDQEQAA
MAB_2434|M.abscessus_ATCC_1997 LGHYLDAAGIRIAYSTSAVVLAQTFVSLPFLVISLQGALTTTGQRYDEVA
MAV_2861|M.avium_104 LGHYLEAAGISVAFSTTAVVLAQTFVSLPFLVISLEGAARTAGADFEVVA
Mvan_3092|M.vanbaalenii_PYR-1 -----------TITGFWGAALVLTLVSYPLVLLTTMAALARVDPAQEEVA
Mflv_3362|M.gilvum_PYR-GCK -----------TAAGFWGAALVLTLVSYPLVLLTTMAALARVDPAQEEVA
MSMEG_3635|M.smegmatis_MC2_155 -----------QVAGFWGAALVLVLVSYPLVFLTTMAALSRVDPALEEVA
TH_0284|M.thermoresistible__bu -----------TISGFWGSTLVLVLVSYPLVMLTTMAALSRVDPAQEEVA
MLBr_02093|M.leprae_Br4923 -----------FQQSAFAVSLALVLLMLPVVVRSTEEILRLVPDELREAC
. . * :: *.:. ..
Mb2420c|M.bovis_AF2122/97 ATLGSGWWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVIIVSSNL--
Rv2398c|M.tuberculosis_H37Rv ATLGSGWWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVIIVSSNL--
MMAR_3716|M.marinum_M ATLGSGWWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVLMVSSNL--
MUL_3659|M.ulcerans_Agy99 ATLGSGWWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVLMVSSNL--
MAB_2434|M.abscessus_ATCC_1997 ASLGAPPTTVLRRVSLPLVMPALASGTVLAFARSLGEFGATLTFAGSR--
MAV_2861|M.avium_104 ATLGARPTTVWWRVTLPLLLPGVVSGAVLAFARSLGEFGATLTFAGSR--
Mvan_3092|M.vanbaalenii_PYR-1 RSLGLGGVAVLFRVTLRQARPAIAAGALLVALYVLSDFGAVAAMR-----
Mflv_3362|M.gilvum_PYR-GCK RSLGLGGVATLFRVTLRQTRAAIAAGALLVALYVLSDFGAVAAMR-----
MSMEG_3635|M.smegmatis_MC2_155 RSLGHGGFSVLFRVTLRQARGAITAGALLVALYVLSDFGAVAAMR-----
TH_0284|M.thermoresistible__bu RSLGLGGWRVLFRVTLRQSRAAITAGALLVALYVLSDFGAVAAMR-----
MLBr_02093|M.leprae_Br4923 YALGIPKWKTIVRIVFPIATPGIISGVLLSIARVIGETAPVLVLVGYSRS
:** . *: : .: * :* :.: ... .
Mb2420c|M.bovis_AF2122/97 ------PGTSQTLTLLVSDRYH----RGAEYGAYALSTLLMAVSVVVLIV
Rv2398c|M.tuberculosis_H37Rv ------PGTSQTLTLLVSDRYH----RGAEYGAYALSTLLMAVSVVVLIV
MMAR_3716|M.marinum_M ------PGTSQTLTLLVSDRYH----RGAEYGAYALSTLLMAVAVVVLIV
MUL_3659|M.ulcerans_Agy99 ------PGTSQTLTLLVSDRYH----RGAGYGAYALSTLLMAVAVVVLIV
MAB_2434|M.abscessus_ATCC_1997 ------QGVTRTLPLEIYLQRE----SDPQ-AAVALSLLLVAVAAVVLAV
MAV_2861|M.avium_104 ------QGVTRTLPLEIYLQRV----TDAD-AAVALSILLVAVAAVVVLG
Mvan_3092|M.vanbaalenii_PYR-1 ---------FEAFTWVIYGAYR----SGFNPSRAAVLSLVLMVFAVALVV
Mflv_3362|M.gilvum_PYR-GCK ---------YEAFTWVIYGAYR----SGFNPSRAAVLSLVLIVFAVLLVV
MSMEG_3635|M.smegmatis_MC2_155 ---------YEAFTWVIYGAYR----SGFNPSRAAVLSLVLLVLAVLLVT
TH_0284|M.thermoresistible__bu ---------YEAFTWVIYGAYR----SGFNPSRAAVLALVLLVFAVVLVL
MLBr_02093|M.leprae_Br4923 INFDIFDGNMASLPLLIYTELTNPEYAGFLRVWGAALTLIILVAGINLFG
::. : . * *:: * : :
Mb2420c|M.bovis_AF2122/97 QMVLDAHRARAVSEG-----------------------------------
Rv2398c|M.tuberculosis_H37Rv QMVLDARRARAVSEG-----------------------------------
MMAR_3716|M.marinum_M QVALDVRRSRTTSRA-----------------------------------
MUL_3659|M.ulcerans_Agy99 QVALDVRRSRTTSRA-----------------------------------
MAB_2434|M.abscessus_ATCC_1997 VGARTRRPAGGGYE------------------------------------
MAV_2861|M.avium_104 LGAR--RLTGTDAR------------------------------------
Mvan_3092|M.vanbaalenii_PYR-1 AEHRARGRAAASRIGGGSPRPAPLNRLGPWSPLALLVPAAVLAAAVAVPT
Mflv_3362|M.gilvum_PYR-GCK GEHRARGVAAAGRIGGGAPRPAPVSRLGRWRWPALAVPAVVLTAALVVPG
MSMEG_3635|M.smegmatis_MC2_155 AEARARGIAAA-RIGGGTPRPAPLNRLGRWWPAALVAPIAVLMAAIGLPT
TH_0284|M.thermoresistible__bu AEARARGRAAASRVGGGTPRXX----------------------------
MLBr_02093|M.leprae_Br4923 AAFRFLATRRCSGCR-----------------------------------
Mb2420c|M.bovis_AF2122/97 --------------------------------------------------
Rv2398c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3716|M.marinum_M --------------------------------------------------
MUL_3659|M.ulcerans_Agy99 --------------------------------------------------
MAB_2434|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2861|M.avium_104 --------------------------------------------------
Mvan_3092|M.vanbaalenii_PYR-1 VELAGWLLTAGPRWDVAEWLDALGSTVWLSAAAAVVSTAAALPLGVLAAR
Mflv_3362|M.gilvum_PYR-GCK IELMDWLLAAGMQWNVGEWLGALGSTVWLSAAAALVSTAAALPLGVLAAR
MSMEG_3635|M.smegmatis_MC2_155 VILVRWLLTAGARWDAQQWVDALTATLWLSFVTAIVCTFAALPLGVLAAR
TH_0284|M.thermoresistible__bu -------XRSGPDWRR----------------------------------
MLBr_02093|M.leprae_Br4923 --------------------------------------------------
Mb2420c|M.bovis_AF2122/97 --------------------------------------------------
Rv2398c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3716|M.marinum_M --------------------------------------------------
MUL_3659|M.ulcerans_Agy99 --------------------------------------------------
MAB_2434|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2861|M.avium_104 --------------------------------------------------
Mvan_3092|M.vanbaalenii_PYR-1 HRDRATRTLEGASYVAHGLPAIVIAISMVSLGVLLLRPIYQREPLLILAY
Mflv_3362|M.gilvum_PYR-GCK HRDRVTRALEGASFLAHGLPSIVIAISMVSLGVLLLRPIYQREPLLILAY
MSMEG_3635|M.smegmatis_MC2_155 YRDRVTRVLEGASYVAHGLPAIVIGISMVSLGVLVLRPLYQREPLLILAY
TH_0284|M.thermoresistible__bu --------------------------------------------------
MLBr_02093|M.leprae_Br4923 --------------------------------------------------
Mb2420c|M.bovis_AF2122/97 --------------------------------------------------
Rv2398c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3716|M.marinum_M --------------------------------------------------
MUL_3659|M.ulcerans_Agy99 --------------------------------------------------
MAB_2434|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2861|M.avium_104 --------------------------------------------------
Mvan_3092|M.vanbaalenii_PYR-1 TVLFVPMAIGSIRAAVEAAPIRLEEVARSLGRPPVRAFGAVTARVALPGI
Mflv_3362|M.gilvum_PYR-GCK AVLFVPMAIGSIRASVQATPVRLEEVARSLGRPPVRAFATVTARVALPGI
MSMEG_3635|M.smegmatis_MC2_155 AVLLIPLAVGSVRAAIESTPARLEEVARSLGRNPLRAFTTVTARLSVPGI
TH_0284|M.thermoresistible__bu --------------------------------------------------
MLBr_02093|M.leprae_Br4923 --------------------------------------------------
Mb2420c|M.bovis_AF2122/97 --------------------------------------------------
Rv2398c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3716|M.marinum_M --------------------------------------------------
MUL_3659|M.ulcerans_Agy99 --------------------------------------------------
MAB_2434|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2861|M.avium_104 --------------------------------------------------
Mvan_3092|M.vanbaalenii_PYR-1 AAGAALVLLTCMKELPVTLLLHPTGTDTLATRLWGYSSVSDYAAAAPYAA
Mflv_3362|M.gilvum_PYR-GCK AAGAALVLLTCMKELPVTLLLHPTGTDTLATRLWGYSSISDYAAAAPYAA
MSMEG_3635|M.smegmatis_MC2_155 AAAAALVLLTCMKELPVTLLLHPTGTDTLATRLWGHSAVSDYAAAAPYAA
TH_0284|M.thermoresistible__bu --------------------------------------------------
MLBr_02093|M.leprae_Br4923 --------------------------------------------------
Mb2420c|M.bovis_AF2122/97 --------------------------
Rv2398c|M.tuberculosis_H37Rv --------------------------
MMAR_3716|M.marinum_M --------------------------
MUL_3659|M.ulcerans_Agy99 --------------------------
MAB_2434|M.abscessus_ATCC_1997 --------------------------
MAV_2861|M.avium_104 --------------------------
Mvan_3092|M.vanbaalenii_PYR-1 ALLLFAAVPTAVLGMWGTDDAGVRSD
Mflv_3362|M.gilvum_PYR-GCK ALLLFAAVPTAVLGLWSTRSAEVRVD
MSMEG_3635|M.smegmatis_MC2_155 ALLVFAAIPTAVLGAWTAGRTGVRSD
TH_0284|M.thermoresistible__bu --------------------------
MLBr_02093|M.leprae_Br4923 --------------------------