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LVAAGAAVVLATLVPLVYLGERAAERGWAFVFDELFQPRTAALVGRSLALVALVTAACVVLGVGLAVLVS RTDLRGRRVLAVVLTLPLAMPSYLLAYLWVSAYPQVAGFWGAALVLVLVSYPLVFLTTMAALSRVDPALE EVARSLGHGGFSVLFRVTLRQARGAITAGALLVALYVLSDFGAVAAMRYEAFTWVIYGAYRSGFNPSRAA VLSLVLLVLAVLLVTAEARARGIAAARIGGGTPRPAPLNRLGRWWPAALVAPIAVLMAAIGLPTVILVRW LLTAGARWDAQQWVDALTATLWLSFVTAIVCTFAALPLGVLAARYRDRVTRVLEGASYVAHGLPAIVIGI SMVSLGVLVLRPLYQREPLLILAYAVLLIPLAVGSVRAAIESTPARLEEVARSLGRNPLRAFTTVTARLS VPGIAAAAALVLLTCMKELPVTLLLHPTGTDTLATRLWGHSAVSDYAAAAPYAAALLVFAAIPTAVLGAW TAGRTGVRSD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3635 | - | - | 100% (501) | iron(III)-transport system permease protein SfuB |
| M. smegmatis MC2 155 | MSMEG_4532 | cysT | 4e-15 | 26.74% (258) | sulfate ABC transporter, permease protein CysT |
| M. smegmatis MC2 155 | MSMEG_4531 | cysW | 3e-14 | 25.71% (245) | sulfate ABC transporter, permease protein CysW |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2420c | cysW | 9e-16 | 26.23% (244) | sulfate-transport integral membrane protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_3362 | - | 0.0 | 77.09% (502) | binding-protein-dependent transport systems inner membrane |
| M. tuberculosis H37Rv | Rv2398c | cysW | 2e-15 | 26.36% (258) | sulfate-transport integral membrane protein ABC transporter |
| M. leprae Br4923 | MLBr_01088 | - | 2e-07 | 27.85% (158) | putative ABC-transport protein, inner membrane component |
| M. abscessus ATCC 19977 | MAB_1504 | - | 2e-15 | 28.87% (194) | ABC transporter permease |
| M. marinum M | MMAR_3716 | cysW | 2e-15 | 26.69% (251) | sulfate-transport integral membrane protein ABC transporter |
| M. avium 104 | MAV_1784 | cysW | 1e-13 | 25.88% (255) | sulfate ABC transporter, permease protein CysW |
| M. thermoresistible (build 8) | TH_0284 | - | 1e-105 | 81.71% (246) | iron(III)-transport system permease protein SfuB |
| M. ulcerans Agy99 | MUL_3659 | cysW | 1e-15 | 26.69% (251) | sulfate-transport integral membrane protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_3092 | - | 0.0 | 79.28% (502) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3362|M.gilvum_PYR-GCK -----------MSRLGRPPAGLLLPAALVAACTLVPLVYLFERAFERGLP
Mvan_3092|M.vanbaalenii_PYR-1 --------MPVITARSRPPALLLLPAALVAAGTLIPLVYLVERALGRGWP
MSMEG_3635|M.smegmatis_MC2_155 --------------------MLVAAGAAVVLATLVPLVYLGERAAERGWA
TH_0284|M.thermoresistible__bu -------VLLAARPRRRTPILLLMPAAAVVTATLLPLVYLVQRALERGWA
Mb2420c|M.bovis_AF2122/97 ----------MTSLPAARYLVRSVALGYVFVLLIVPVALILWRTFEPGFG
Rv2398c|M.tuberculosis_H37Rv ----------MTSLPAARYLVRSVALGYVFVLLIVPVALILWRTFEPGFG
MMAR_3716|M.marinum_M ----------MTSSPLVRYLLRAIALTYVFALLVVPVGVILWRTFEPGLG
MUL_3659|M.ulcerans_Agy99 ----------MTSSPLVRYLLRAIALTYVFALLVVPVGVILWRTFEPGLG
MAV_1784|M.avium_104 ----------MTSSPGVRYGLRFVALAYIFVLLVIPVSLILWRTFRPGFG
MAB_1504|M.abscessus_ATCC_1997 ---------MLLWNGRSRLILWSVFAVVITVVFIAPIATVVLAGFSGAWT
MLBr_01088|M.leprae_Br4923 MGIEKVKVTAGVRVGARRATIWVIIDTFVVGYALLPVLWILSLSLKPAST
: : *: : .
Mflv_3362|M.gilvum_PYR-GCK --------------FVVDELLQPRTAAMVGRSLLLVSVVTAACVVLGVGL
Mvan_3092|M.vanbaalenii_PYR-1 --------------FVVDELLQPRTAALVGRSLLLVAVVTAACVVLGVGL
MSMEG_3635|M.smegmatis_MC2_155 --------------FVFDELFQPRTAALVGRSLALVALVTAACVVLGVGL
TH_0284|M.thermoresistible__bu --------------FVLHELAQPRTAALIGRSLLLVVVVTAACVVLGVGF
Mb2420c|M.bovis_AF2122/97 --------------QFYAWISTPAAISALNLSLLVVAIVVPLNVIFGVTT
Rv2398c|M.tuberculosis_H37Rv --------------QFYAWISTPAAISALNLSLLVVAIVVPLNVIFGVTT
MMAR_3716|M.marinum_M --------------QFYDWISTPAAISALHLSLLLVAIVVPLNVIFGILT
MUL_3659|M.ulcerans_Agy99 --------------QFYDWISTPAAISALHLSLLLVAIVVPLEVIFGIPT
MAV_1784|M.avium_104 --------------QFYAWVSTPAAISALNLTLLVVAIVVPLNVFFGIPT
MAB_1504|M.abscessus_ATCC_1997 GP-----LPTQLSFMRYEKALGGDDLASMAVSLQTAVMSSGVALLLGTWA
MLBr_01088|M.leprae_Br4923 VKDGKLIPSLVTFDNYRGIFRSDLFSSALINSIGIGLTTTVIAVMFGAMA
: : :: :.:*
Mflv_3362|M.gilvum_PYR-GCK AVLVTRTDLRGRRVLAVALTLPLAMP----SYLLAYLWVSA---------
Mvan_3092|M.vanbaalenii_PYR-1 AVLVTRTNLRGRRALAVSLTLPLAMP----SYLLAYLWVSA---------
MSMEG_3635|M.smegmatis_MC2_155 AVLVSRTDLRGRRVLAVVLTLPLAMP----SYLLAYLWVSA---------
TH_0284|M.thermoresistible__bu AVLVNRTDLVARRVLAVALTLPLAIP----SYLLAFLWVSL---------
Mb2420c|M.bovis_AF2122/97 ALVLARNRFRGKGVLQAIIDLPFAVSPVIVGVSLILLWGSAGALGFVEQD
Rv2398c|M.tuberculosis_H37Rv ALVLARNRFRGKGVLQAIIDLPFAVSPVIVGVSLILLWGSAGALGFVEQD
MMAR_3716|M.marinum_M ALLLARNRFRGKGVLQAIIDLPFAVSPVIVGTALILLWGSAGALGFVERD
MUL_3659|M.ulcerans_Agy99 ALLLARNRFRGKGVLQAIIDLPFAVSPVIVGTALILLWGSAGALDFVERD
MAV_1784|M.avium_104 ALVLARNRFRGKGVLQAIIDLPFAVSPVIVGVALIVLWGSAGALGFVEKD
MAB_1504|M.abscessus_ATCC_1997 ALSVREVPSWLRRVIDAVFHLPIAIPSVAIGLGLLTAFNEP---------
MLBr_01088|M.leprae_Br4923 AYAIARLAFPGKRLLVGTTLLVTMFPAISLVTPLFNIERRVG--------
* : . : : * .. *
Mflv_3362|M.gilvum_PYR-GCK --FPTAAG--FWGAALVLTLVSYPLVLLTTMAALARVDPAQEEVARSLGL
Mvan_3092|M.vanbaalenii_PYR-1 --YPTITG--FWGAALVLTLVSYPLVLLTTMAALARVDPAQEEVARSLGL
MSMEG_3635|M.smegmatis_MC2_155 --YPQVAG--FWGAALVLVLVSYPLVFLTTMAALSRVDPALEEVARSLGH
TH_0284|M.thermoresistible__bu --VPTISG--FWGSTLVLVLVSYPLVMLTTMAALSRVDPAQEEVARSLGL
Mb2420c|M.bovis_AF2122/97 LGFKIIFG--LPGIVLASMFVTCPFVVREVEPVLHELGTDQEQAAATLGS
Rv2398c|M.tuberculosis_H37Rv LGFKIIFG--LPGIVLGSMFVTCPFVVREVEPVLHELGTDQEQAAATLGS
MMAR_3716|M.marinum_M LGIRIIFG--LPGMVLASIFVTLPFVVREVEPVLHELGTDQEQAAATLGS
MUL_3659|M.ulcerans_Agy99 LGIRIIFG--LPGMVLASIFVTLPFVVREVEPVLHELGTDQEQAAATLGS
MAV_1784|M.avium_104 LGFKIIFG--LPGIVLASIFVTLPFVVREVEPVLHELGTDQEEAAATLGS
MAB_1504|M.abscessus_ATCC_1997 ---PLLLGGTKWIVIVAHTALVLAFAFSSVSAALERLDPAYRQVAESLGA
MLBr_01088|M.leprae_Br4923 -LFDTWAG-----LILPYITFALPLAIYTLSAFFAEIPWDLEKAAKMDGA
* : . .:.. . : .: .:.* *
Mflv_3362|M.gilvum_PYR-GCK GGVATLFRVTLRQTRAAIAAGALLVALYVLSDFGAVAAMR------YEAF
Mvan_3092|M.vanbaalenii_PYR-1 GGVAVLFRVTLRQARPAIAAGALLVALYVLSDFGAVAAMR------FEAF
MSMEG_3635|M.smegmatis_MC2_155 GGFSVLFRVTLRQARGAITAGALLVALYVLSDFGAVAAMR------YEAF
TH_0284|M.thermoresistible__bu GGWRVLFRVTLRQSRAAITAGALLVALYVLSDFGAVAAMR------YEAF
Mb2420c|M.bovis_AF2122/97 GWWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVIIVSSNLPGTSQTL
Rv2398c|M.tuberculosis_H37Rv GWWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVIIVSSNLPGTSQTL
MMAR_3716|M.marinum_M GWWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVLMVSSNLPGTSQTL
MUL_3659|M.ulcerans_Agy99 GWWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVLMVSSNLPGTSQTL
MAV_1784|M.avium_104 GWWQTFWRITLPSIRWGLTYGIVLTIARSLGEYGAVLMVSSNLPGKSQTL
MAB_1504|M.abscessus_ATCC_1997 GSVRVVRTVTLPLLMPSLGAAAGLAIALSMGELGATVMVYP---SSWRTL
MLBr_01088|M.leprae_Br4923 TSGQAFRKVIVPLAAPGLVTAAILVFIFAWNDLLLALSLTSTKAAITAPV
.. : : .: . *. .: . : ..
Mflv_3362|M.gilvum_PYR-GCK TWVIYGAYRSGFNPSRAAVLSLVLIVFAVLLVVGEHRARGVAAAGRIGGG
Mvan_3092|M.vanbaalenii_PYR-1 TWVIYGAYRSGFNPSRAAVLSLVLMVFAVALVVAEHRARGRAAASRIGGG
MSMEG_3635|M.smegmatis_MC2_155 TWVIYGAYRSGFNPSRAAVLSLVLLVLAVLLVTAEARARGIAAA-RIGGG
TH_0284|M.thermoresistible__bu TWVIYGAYRSGFNPSRAAVLALVLLVFAVVLVLAEARARGRAAASRVGGG
Mb2420c|M.bovis_AF2122/97 TLLVSDRYHRGAEYGAYALSTLLMAVSVVVLIVQMVLDAHRARAVSEG--
Rv2398c|M.tuberculosis_H37Rv TLLVSDRYHRGAEYGAYALSTLLMAVSVVVLIVQMVLDARRARAVSEG--
MMAR_3716|M.marinum_M TLLVSDRYHRGAEYGAYALSTLLMAVAVVVLIVQVALDVRRSRTTSRA--
MUL_3659|M.ulcerans_Agy99 TLLVSDRYHRGAGYGAYALSTLLMAVAVVVLIVQVALDVRRSRTTSRA--
MAV_1784|M.avium_104 TLLVSDRYNRGAEYGAYALSTLLMGVAVLVLVFQVVLDARRGRAARQA--
MAB_1504|M.abscessus_ATCC_1997 PVTIFGLSDRGQVFSAAASTTLLLMVTLLALLVVGRLRGKVAFR------
MLBr_01088|M.leprae_Br4923 AITNFTGSSQFEEPTGSIAAGAIVITAPIIVFVWIFQRRIVAGLTSGAVK
. :: . : :. .
Mflv_3362|M.gilvum_PYR-GCK APRPAPVSRLGRWRWPALAVPAVVLTAALVVPGIELMDWLLAAGMQWNVG
Mvan_3092|M.vanbaalenii_PYR-1 SPRPAPLNRLGPWSPLALLVPAAVLAAAVAVPTVELAGWLLTAGPRWDVA
MSMEG_3635|M.smegmatis_MC2_155 TPRPAPLNRLGRWWPAALVAPIAVLMAAIGLPTVILVRWLLTAGARWDAQ
TH_0284|M.thermoresistible__bu TPRXX-----------------------------------XRSGPDWRR-
Mb2420c|M.bovis_AF2122/97 --------------------------------------------------
Rv2398c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3716|M.marinum_M --------------------------------------------------
MUL_3659|M.ulcerans_Agy99 --------------------------------------------------
MAV_1784|M.avium_104 --------------------------------------------------
MAB_1504|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01088|M.leprae_Br4923 G-------------------------------------------------
Mflv_3362|M.gilvum_PYR-GCK EWLGALGSTVWLSAAAALVSTAAALPLGVLAARHRDRVTRALEGASFLAH
Mvan_3092|M.vanbaalenii_PYR-1 EWLDALGSTVWLSAAAAVVSTAAALPLGVLAARHRDRATRTLEGASYVAH
MSMEG_3635|M.smegmatis_MC2_155 QWVDALTATLWLSFVTAIVCTFAALPLGVLAARYRDRVTRVLEGASYVAH
TH_0284|M.thermoresistible__bu --------------------------------------------------
Mb2420c|M.bovis_AF2122/97 --------------------------------------------------
Rv2398c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3716|M.marinum_M --------------------------------------------------
MUL_3659|M.ulcerans_Agy99 --------------------------------------------------
MAV_1784|M.avium_104 --------------------------------------------------
MAB_1504|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01088|M.leprae_Br4923 --------------------------------------------------
Mflv_3362|M.gilvum_PYR-GCK GLPSIVIAISMVSLGVLLLRPIYQREPLLILAYAVLFVPMAIGSIRASVQ
Mvan_3092|M.vanbaalenii_PYR-1 GLPAIVIAISMVSLGVLLLRPIYQREPLLILAYTVLFVPMAIGSIRAAVE
MSMEG_3635|M.smegmatis_MC2_155 GLPAIVIGISMVSLGVLVLRPLYQREPLLILAYAVLLIPLAVGSVRAAIE
TH_0284|M.thermoresistible__bu --------------------------------------------------
Mb2420c|M.bovis_AF2122/97 --------------------------------------------------
Rv2398c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3716|M.marinum_M --------------------------------------------------
MUL_3659|M.ulcerans_Agy99 --------------------------------------------------
MAV_1784|M.avium_104 --------------------------------------------------
MAB_1504|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01088|M.leprae_Br4923 --------------------------------------------------
Mflv_3362|M.gilvum_PYR-GCK ATPVRLEEVARSLGRPPVRAFATVTARVALPGIAAGAALVLLTCMKELPV
Mvan_3092|M.vanbaalenii_PYR-1 AAPIRLEEVARSLGRPPVRAFGAVTARVALPGIAAGAALVLLTCMKELPV
MSMEG_3635|M.smegmatis_MC2_155 STPARLEEVARSLGRNPLRAFTTVTARLSVPGIAAAAALVLLTCMKELPV
TH_0284|M.thermoresistible__bu --------------------------------------------------
Mb2420c|M.bovis_AF2122/97 --------------------------------------------------
Rv2398c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3716|M.marinum_M --------------------------------------------------
MUL_3659|M.ulcerans_Agy99 --------------------------------------------------
MAV_1784|M.avium_104 --------------------------------------------------
MAB_1504|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01088|M.leprae_Br4923 --------------------------------------------------
Mflv_3362|M.gilvum_PYR-GCK TLLLHPTGTDTLATRLWGYSSISDYAAAAPYAAALLLFAAVPTAVLGLWS
Mvan_3092|M.vanbaalenii_PYR-1 TLLLHPTGTDTLATRLWGYSSVSDYAAAAPYAAALLLFAAVPTAVLGMWG
MSMEG_3635|M.smegmatis_MC2_155 TLLLHPTGTDTLATRLWGHSAVSDYAAAAPYAAALLVFAAIPTAVLGAWT
TH_0284|M.thermoresistible__bu --------------------------------------------------
Mb2420c|M.bovis_AF2122/97 --------------------------------------------------
Rv2398c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3716|M.marinum_M --------------------------------------------------
MUL_3659|M.ulcerans_Agy99 --------------------------------------------------
MAV_1784|M.avium_104 --------------------------------------------------
MAB_1504|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01088|M.leprae_Br4923 --------------------------------------------------
Mflv_3362|M.gilvum_PYR-GCK TRSAEVRVD
Mvan_3092|M.vanbaalenii_PYR-1 TDDAGVRSD
MSMEG_3635|M.smegmatis_MC2_155 AGRTGVRSD
TH_0284|M.thermoresistible__bu ---------
Mb2420c|M.bovis_AF2122/97 ---------
Rv2398c|M.tuberculosis_H37Rv ---------
MMAR_3716|M.marinum_M ---------
MUL_3659|M.ulcerans_Agy99 ---------
MAV_1784|M.avium_104 ---------
MAB_1504|M.abscessus_ATCC_1997 ---------
MLBr_01088|M.leprae_Br4923 ---------