For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TSLPAARYLVRSVALGYVFVLLIVPVALILWRTFEPGFGQFYAWISTPAAISALNLSLLVVAIVVPLNVI FGVTTALVLARNRFRGKGVLQAIIDLPFAVSPVIVGVSLILLWGSAGALGFVEQDLGFKIIFGLPGIVLG SMFVTCPFVVREVEPVLHELGTDQEQAAATLGSGWWQTFWRITLPSIRWGLTYGIVLTVARTLGEYGAVI IVSSNLPGTSQTLTLLVSDRYHRGAEYGAYALSTLLMAVSVVVLIVQMVLDARRARAVSEG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2398c | cysW | - | 100% (272) | PROBABLE SULFATE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER CYSW |
| M. tuberculosis H37Rv | Rv2399c | cysT | 1e-38 | 32.20% (264) | sulfate-transport integral membrane protein ABC transporter |
| M. tuberculosis H37Rv | Rv1858 | modB | 3e-32 | 35.69% (255) | molbdenum-transport integral membrane protein ABC |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2420c | cysW | 1e-150 | 99.26% (272) | sulfate-transport integral membrane protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_2680 | - | 1e-108 | 73.08% (260) | sulfate ABC transporter, inner membrane subunit CysW |
| M. leprae Br4923 | MLBr_01768 | uspA | 2e-14 | 24.56% (281) | sugar transport integral membrane protein |
| M. abscessus ATCC 19977 | MAB_1654 | - | 1e-117 | 80.15% (267) | sulfate ABC transporter, permease protein CysW |
| M. marinum M | MMAR_3716 | cysW | 1e-133 | 86.67% (270) | sulfate-transport integral membrane protein ABC transporter |
| M. avium 104 | MAV_1784 | cysW | 1e-132 | 85.24% (271) | sulfate ABC transporter, permease protein CysW |
| M. smegmatis MC2 155 | MSMEG_4531 | cysW | 1e-118 | 77.86% (271) | sulfate ABC transporter, permease protein CysW |
| M. thermoresistible (build 8) | TH_2990 | - | 1e-120 | 79.10% (268) | PUTATIVE sulfate ABC transporter, permease protein CysW |
| M. ulcerans Agy99 | MUL_3659 | cysW | 1e-131 | 85.56% (270) | sulfate-transport integral membrane protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_3873 | - | 1e-118 | 76.78% (267) | sulfate ABC transporter, inner membrane subunit CysW |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2398c|M.tuberculosis_H37Rv ------------------------------------------------MT
Mb2420c|M.bovis_AF2122/97 ------------------------------------------------MT
MMAR_3716|M.marinum_M ------------------------------------------------MT
MUL_3659|M.ulcerans_Agy99 ------------------------------------------------MT
MAV_1784|M.avium_104 ------------------------------------------------MT
MAB_1654|M.abscessus_ATCC_1997 ------------------------------------------------MT
MSMEG_4531|M.smegmatis_MC2_155 ------------------------------------------------MT
Mvan_3873|M.vanbaalenii_PYR-1 ------------------------------------------------MT
TH_2990|M.thermoresistible__bu ---------------------------------------VTSGSNGSGLT
Mflv_2680|M.gilvum_PYR-GCK ------------------------------------------------MI
MLBr_01768|M.leprae_Br4923 MCAHFNTSMTNTGDDTEQSDEVGSISRLRGRKTHRTRALTKNHPRSIALA
:
Rv2398c|M.tuberculosis_H37Rv SLPAARYLVRSVALGYVFVLLIVPVALILWRTFEP----GFGQFYAWIST
Mb2420c|M.bovis_AF2122/97 SLPAARYLVRSVALGYVFVLLIVPVALILWRTFEP----GFGQFYAWIST
MMAR_3716|M.marinum_M SSPLVRYLLRAIALTYVFALLVVPVGVILWRTFEP----GLGQFYDWIST
MUL_3659|M.ulcerans_Agy99 SSPLVRYLLRAIALTYVFALLVVPVGVILWRTFEP----GLGQFYDWIST
MAV_1784|M.avium_104 SSPGVRYGLRFVALAYIFVLLVIPVSLILWRTFRP----GFGQFYAWVST
MAB_1654|M.abscessus_ATCC_1997 LSPAVKYALRILALLYVAVLLIVPLGLILWRAFAP----GLVQFWEYIST
MSMEG_4531|M.smegmatis_MC2_155 LSPVVRRLLRFTALAYILVLVVVPVGLILWRTFAP----GIGAFVTSIST
Mvan_3873|M.vanbaalenii_PYR-1 LSPVMRHLLRWIALTYVAVLVIVPVGLILWRTFSP----GVGDFFASVGT
TH_2990|M.thermoresistible__bu PARPARYLLRFVALSYVVVLVAVPVGLILWRTFAP----GLGEFIASVTT
Mflv_2680|M.gilvum_PYR-GCK LSLRTRLILRIVALFYVIALLIVPLGAILWQTFAP----GLGAFWASITT
MLBr_01768|M.leprae_Br4923 YALLAPSLFGVVTFLLLPIIVVIWLSLFRWDLLGPLHYVGLANWRSVLTD
. :: : :: : :. : * : * *. : :
Rv2398c|M.tuberculosis_H37Rv PAAISALNLSLLVVAIVVPLNVIFGVTTALVLARNRFRGKGVLQAIIDLP
Mb2420c|M.bovis_AF2122/97 PAAISALNLSLLVVAIVVPLNVIFGVTTALVLARNRFRGKGVLQAIIDLP
MMAR_3716|M.marinum_M PAAISALHLSLLLVAIVVPLNVIFGILTALLLARNRFRGKGVLQAIIDLP
MUL_3659|M.ulcerans_Agy99 PAAISALHLSLLLVAIVVPLEVIFGIPTALLLARNRFRGKGVLQAIIDLP
MAV_1784|M.avium_104 PAAISALNLTLLVVAIVVPLNVFFGIPTALVLARNRFRGKGVLQAIIDLP
MAB_1654|M.abscessus_ATCC_1997 PAAISAFNLSLLVVAIVVPLNVIFGVPTALVLARNKFRGKGVLQAIIDLP
MSMEG_4531|M.smegmatis_MC2_155 PAAISALNLSLLVVAIVVPLNVLFGVPTALVLARNKFRGKSALQAVIDLP
Mvan_3873|M.vanbaalenii_PYR-1 PAAISALQLSLLVVAIVVPLNVLFGVPTALVLARNKFRGKSALQAVIDLP
TH_2990|M.thermoresistible__bu PAAISALQLSLLVVAIVVPLNVVFGVPTALVLARNRFRGKAALQAVIDLP
Mflv_2680|M.gilvum_PYR-GCK PAAQSALSLSLLVVAIVVPLNVVFGVSTALVLARRRFRGKNALQAAIDLP
MLBr_01768|M.leprae_Br4923 PNFANSLIVTAVFVAIVVPTQTMLGLLIATMLAR-QLPGTGVFRTLYVLP
* .:: :: :.****** :..:*: * :*** :: *. .::: **
Rv2398c|M.tuberculosis_H37Rv FAVSPVIVGVSLILLWG-SAGALGFVEQ---DLGFKIIFGLPGIVLGSMF
Mb2420c|M.bovis_AF2122/97 FAVSPVIVGVSLILLWG-SAGALGFVEQ---DLGFKIIFGLPGIVLASMF
MMAR_3716|M.marinum_M FAVSPVIVGTALILLWG-SAGALGFVER---DLGIRIIFGLPGMVLASIF
MUL_3659|M.ulcerans_Agy99 FAVSPVIVGTALILLWG-SAGALDFVER---DLGIRIIFGLPGMVLASIF
MAV_1784|M.avium_104 FAVSPVIVGVALIVLWG-SAGALGFVEK---DLGFKIIFGLPGIVLASIF
MAB_1654|M.abscessus_ATCC_1997 FAVSPVIVGVALIVLWG-SAGLLGFVEN---DWKFKIIFGLPGIVLASIF
MSMEG_4531|M.smegmatis_MC2_155 FAVSPVVVGVALILLWG-SAGLFGFVEN---NLGLKIIFGFPGIVLASIF
Mvan_3873|M.vanbaalenii_PYR-1 FAVSPVVVGVALILLWG-SAGLFGFLEN---DFGWRIIFGFPGIVLASIF
TH_2990|M.thermoresistible__bu FAVSPIIVGVALILLWG-TAGFLGFVEN---SLGLKIIFGFPGIVLASIF
Mflv_2680|M.gilvum_PYR-GCK FAVSPVVVGVALIALWG-TAGLFGFVQN---DFGVTVIFGFPGIVLASIF
MLBr_01768|M.leprae_Br4923 WICAPLAIAVLWRWLLAPTDGAFSMVLRHRIEWLSDPSLALPVVSAVVVW
: :*: :.. * . : * :.:: . . :.:* : ::
Rv2398c|M.tuberculosis_H37Rv VTCPFVVREVEPVLHELGTDQEQAAATLGSGWWQTFWRITLPSIRWGLTY
Mb2420c|M.bovis_AF2122/97 VTCPFVVREVEPVLHELGTDQEQAAATLGSGWWQTFWRITLPSIRWGLTY
MMAR_3716|M.marinum_M VTLPFVVREVEPVLHELGTDQEQAAATLGSGWWQTFWRITLPSIRWGLTY
MUL_3659|M.ulcerans_Agy99 VTLPFVVREVEPVLHELGTDQEQAAATLGSGWWQTFWRITLPSIRWGLTY
MAV_1784|M.avium_104 VTLPFVVREVEPVLHELGTDQEEAAATLGSGWWQTFWRITLPSIRWGLTY
MAB_1654|M.abscessus_ATCC_1997 VTLPFVIREVEPVLHEIGDDQEQAAATLGANPWQTFWRITLPSIRWGLTY
MSMEG_4531|M.smegmatis_MC2_155 VTVPFVIREVEPVLHEIGTDQEEAAATLGSTWWQTFWRITLPSIRWGLTY
Mvan_3873|M.vanbaalenii_PYR-1 VTVPFVIREVEPVLHEIGTDQEEASATLGAQWWQTFWRITLPSIRWGLTY
TH_2990|M.thermoresistible__bu VTVPFVIREVEPVLHEIGTDQEEAAATLGATWWQTFWRVTLPSIRWGLTY
Mflv_2680|M.gilvum_PYR-GCK VTLPFVIREVEPVLHEIGTDHEEASATLGANAWQTFWRVTLPSIRWGLTY
MLBr_01768|M.leprae_Br4923 TNVGYVSLSFLAGLLSIPEDINAAARTDGADAWQRFWRITLPMLRPTMFF
.. :* .. . * .: * : *: * *: ** ***:*** :* : :
Rv2398c|M.tuberculosis_H37Rv GIVLTVARTLGEYGAVIIVSSNLPGTSQTLTLLVSDRYHRG---AEYG-A
Mb2420c|M.bovis_AF2122/97 GIVLTVARTLGEYGAVIIVSSNLPGTSQTLTLLVSDRYHRG---AEYG-A
MMAR_3716|M.marinum_M GIVLTVARTLGEYGAVLMVSSNLPGTSQTLTLLVSDRYHRG---AEYG-A
MUL_3659|M.ulcerans_Agy99 GIVLTVARTLGEYGAVLMVSSNLPGTSQTLTLLVSDRYHRG---AGYG-A
MAV_1784|M.avium_104 GIVLTIARSLGEYGAVLMVSSNLPGKSQTLTLLVSDRYNRG---AEYG-A
MAB_1654|M.abscessus_ATCC_1997 GIVLTVARTLGEYGAVIMVSSGLPGKSQTLTLLVSDRHLRG---DEYG-A
MSMEG_4531|M.smegmatis_MC2_155 GIVLTIARTLGEFGAVIMVSSNLPGVSQTLTLLVADRYNRGTADSVYG-A
Mvan_3873|M.vanbaalenii_PYR-1 GIVLTIARTLGEFGAVLMVAANLPGSSQTLTLLVHDRYTRG---AEYG-A
TH_2990|M.thermoresistible__bu GVVLTVARTLGEFGAVLMVSSNLPGVSQTLTLLVHDRYNRG---AEYG-A
Mflv_2680|M.gilvum_PYR-GCK GVVLTVARTLGEFGAVLVVSSNLPGQSQTMTLLVHDRYTRG---DDYG-A
MLBr_01768|M.leprae_Br4923 VLVTGIVSTAQVFDTVYALTD--GGPKSRTDLVAHRIYAEAFGSAAIGRA
:* :. : :.:* :: * .. *:. : .. * *
Rv2398c|M.tuberculosis_H37Rv YALSTLLMAVSVVVLIVQMVLDARRARAVSEG
Mb2420c|M.bovis_AF2122/97 YALSTLLMAVSVVVLIVQMVLDAHRARAVSEG
MMAR_3716|M.marinum_M YALSTLLMAVAVVVLIVQVALDVRRSRTTSRA
MUL_3659|M.ulcerans_Agy99 YALSTLLMAVAVVVLIVQVALDVRRSRTTSRA
MAV_1784|M.avium_104 YALSTLLMGVAVLVLVFQVVLDARRGRAARQA
MAB_1654|M.abscessus_ATCC_1997 YALSVVLMAVALIVLVVQVVLDRNRAKTSK--
MSMEG_4531|M.smegmatis_MC2_155 YAISTLLMAVAVVVLVAQVLLDKRRAKAEQS-
Mvan_3873|M.vanbaalenii_PYR-1 YAISTLLMTVAVLVLIAQVILDARRTRTAK--
TH_2990|M.thermoresistible__bu YAISTLLMAVAVVVLIFQVILDARRAKSNQ--
Mflv_2680|M.gilvum_PYR-GCK YTISTVLMAVAVTVLIAQIVFDAQRTRTRTDD
MLBr_01768|M.leprae_Br4923 SVMAVLLFVVLFGVTVVQHLYFQRRISYELT-
.::.:*: * . * : * .*