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VIKGLVQRSAMPDPAAVLRSLACVAAVAVVAVQWGPQGSATAVVGAAAVAGATALQDSPRGRVTVVLLVT AVAGLAVLLGALTSGFSPLFVAVATLWCFGASMLWALGANPGLIGAASAALLVSAPPVTPTPTSVVVTWL LAVAGGLLQVWVISLWPPLRWRNQRKALVAAYRSLAADARKISDGTVGGGPAADPEPLAALRTAFTAADG PSRRRPATYRGWYALPERIADTLTDVARLPARSDALALALAEAADTLAAVADTSRTGRVGADVAIGRFDS VAATVDGSESVVVQKLSTQLHEAVAMRLGDFVPSTPDAVRLRRPELRTSVRSAVDVMRSHLDRHSPVLRH AVRLAAAVAVGCVVDRYAEGAYGFWIPLTVLMVLRPETAHTYTRCVGRVAGTLVGIVTASAVLVILNPGV AVSAVLALAAVGVACVLSGIGFIAMAAAVTAAAVFLVDIGRPDMPPAVADPVLAVLFGGALALIAHVVLP DDALTRLSQRAGELLRTEIDYAATVIKAYVHELDDPAETMTSAWQRAFRARAAFEATTGAMRMESRELRH WLRSYRTALNAVTSSCTTLEDQLPAQPAVTANREFVLAVDEYVEALRGDPPTAASPWRVDCAELAAAEAR LREAVRRHGPEEGPARLLVAEVDTITRHVSAISVSPSPTSVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3048 | - | - | 100% (672) | protein of unknown function DUF893, YccS/YhfK |
| M. vanbaalenii PYR-1 | Mvan_0100 | - | 3e-13 | 23.42% (696) | membrane protein-like protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3327 | - | 0.0 | 63.70% (675) | protein of unknown function DUF893, YccS/YhfK |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2160 | - | 2e-07 | 25.82% (275) | transmembrane alanine and valine and leucine rich protein |
| M. avium 104 | MAV_3441 | - | 1e-05 | 30.66% (137) | hypothetical protein MAV_3441 |
| M. smegmatis MC2 155 | MSMEG_3570 | - | 1e-152 | 46.47% (665) | hypothetical protein MSMEG_3570 |
| M. thermoresistible (build 8) | TH_4065 | - | 2e-94 | 48.13% (374) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3048|M.vanbaalenii_PYR-1 MIKG----LVQRSAMPDPAAVLRSLACVAAVAVVAVQWGPQGSATAVVGA
Mflv_3327|M.gilvum_PYR-GCK MIMG----LTVRSVLPDAAAALRSLAAVGVIAVIAALWGPPGSATSAVAV
MSMEG_3570|M.smegmatis_MC2_155 MQTGGPAADALRLSTPDPGAVARSLVGALAMTTAALALASPPAAMWTLGA
TH_4065|M.thermoresistible__bu --------------------------------------------------
MMAR_2160|M.marinum_M --------------------------------------------------
MAV_3441|M.avium_104 --------------------------------------------------
Mvan_3048|M.vanbaalenii_PYR-1 AAVAGATALQDSPRGRVTVVLLVTAVAGLAVLLGALTSGFSPLFVAVATL
Mflv_3327|M.gilvum_PYR-GCK AAVAGATAFQDSPRSRIPLVYLVSGLCGVAVLLGTAVSGLPVLFLLLCAL
MSMEG_3570|M.smegmatis_MC2_155 GVIAGAVALQRSPGGRVPLVVTASLEMAIVVALAVLTGSHDVVFVLAVAV
TH_4065|M.thermoresistible__bu --------------------------------------------------
MMAR_2160|M.marinum_M --------------------------------------------------
MAV_3441|M.avium_104 --------------------------------------------------
Mvan_3048|M.vanbaalenii_PYR-1 WCFGASMLWALGANPGLIGAASAALLVSAPPVTPTPTSV----VVTWLLA
Mflv_3327|M.gilvum_PYR-GCK WCAGVAMLWAHGPNTGLIGAASGALMVAATSAG-TPVSVGAA-LGTAALA
MSMEG_3570|M.smegmatis_MC2_155 WCFAAGMQWSVGANAGLIASAASSLLVIAPPDGYATAPTAFDGLLAPLLV
TH_4065|M.thermoresistible__bu --------------------------------------------------
MMAR_2160|M.marinum_M --------------------------------------------------
MAV_3441|M.avium_104 --------------------------------------------------
Mvan_3048|M.vanbaalenii_PYR-1 VAGGLLQVWVISLWPPLRWRNQRKALVAAYRSLAADARKISDGTVGGGPA
Mflv_3327|M.gilvum_PYR-GCK VVGGLSQAVVLAVWPPQRWRAQRDAVVAAYRSLAADARRLADGRDDG-WA
MSMEG_3570|M.smegmatis_MC2_155 FGAGVLQAVLIATLPPHRWRVQREGLTRAYRSLATDARNVAADRSAD---
TH_4065|M.thermoresistible__bu --------------------------------------------------
MMAR_2160|M.marinum_M --------------------------------------------------
MAV_3441|M.avium_104 --------------------------------------------------
Mvan_3048|M.vanbaalenii_PYR-1 ADPEPLAALRTAFTAADGPSRRRPATYRGWYALPERIADTLTDV----AR
Mflv_3327|M.gilvum_PYR-GCK VDTEPLVALREAFTDVSGPTLRRPAVYRGWYALPERIAATLTDM----AN
MSMEG_3570|M.smegmatis_MC2_155 VDDAPLTWLREVFADS--EAAQRSRANYGGYQVPERIAVTLAELRSAYAE
TH_4065|M.thermoresistible__bu --------------------------------------------------
MMAR_2160|M.marinum_M --------------------------------------------------
MAV_3441|M.avium_104 --------------------------------------------------
Mvan_3048|M.vanbaalenii_PYR-1 LPARSDALALALAEAADTLAAVADTSRTGRVGADVAIGRFDSVAATVDGS
Mflv_3327|M.gilvum_PYR-GCK GP-RSEALSRVLEEAADTMAAVADTSRAGRVGTHVSIGRFDSVVTEIDGP
MSMEG_3570|M.smegmatis_MC2_155 PASDAPGVPRLLAAAAALLDAIADQGHTARRDAEHALVRVDSAVASVDGP
TH_4065|M.thermoresistible__bu ------------------------------------------XAAQVS--
MMAR_2160|M.marinum_M --------------------------------------------------
MAV_3441|M.avium_104 --------------------------------------------------
Mvan_3048|M.vanbaalenii_PYR-1 ESVVVQKLSTQLHEAVAMRLGDFVPSTPDAVRLRRPELRTSVRSAVDVMR
Mflv_3327|M.gilvum_PYR-GCK ESGTVRRLSALLHEVAAMRLGDFVPSTPDAVRLRRPELPTSVRSAMDTVR
MSMEG_3570|M.smegmatis_MC2_155 EKALAQRLGDLLREAAVLRFG----------QLHRPDLIGSLASAPSVVR
TH_4065|M.thermoresistible__bu -------------DAVALRFG----------RLHR----RTPGDVLAAVQ
MMAR_2160|M.marinum_M ------------------------------------MEISLLTRAADGSL
MAV_3441|M.avium_104 -----------------------------------MRGSAVPSLVRTAAR
.
Mvan_3048|M.vanbaalenii_PYR-1 SHLDRHSPVLRHAVRLAAAVAVGCVVDR-YAEGAYGFWIPLTVLMVLRPE
Mflv_3327|M.gilvum_PYR-GCK GHLNQDSPVLRHAVRVGAAVGLGGGIAQ-YAGIPYGYWIPLTALLVLRPE
MSMEG_3570|M.smegmatis_MC2_155 SHLRWTSPILRHAVRLSAATALAAVAAR-FGGVEHGHWIALTVLVVLRPE
TH_4065|M.thermoresistible__bu AQLTWPSPVLRHALRLAVGTAGAIALAR-YGDLDQGHWMALTVLLVLRPE
MMAR_2160|M.marinum_M AAVRQLRTALWPITQASVTAGLAWFLTHDVLDHPQPFFAPISAAVCMSAT
MAV_3441|M.avium_104 AGGKRLGAVWFNLLQTSLAAGLSWYLAHDVLDHPQPFFAPIAAAVSLSTS
. . : . .. . : .: .::. : : .
Mvan_3048|M.vanbaalenii_PYR-1 TAHTYTRCVGRVAGTLVGIVTASAVLVILNPGVAVSAVLALAAVGVACVL
Mflv_3327|M.gilvum_PYR-GCK TAHTYTRCVGRVAGTAAGVVVASAVLVPFAPAPVVSLGFAVVAVGIAYLV
MSMEG_3570|M.smegmatis_MC2_155 TAHTYTRCAGRIATLAAGVTVASGLTLMWQPEALPAAACALALVALAYWL
TH_4065|M.thermoresistible__bu TAHTYTRCGGRILGLATGVAVATVPIVLWRPDGLVAATVAALLVAATYLA
MMAR_2160|M.marinum_M NVLRARRAVQMVGGVALGIVVGAGVQAVLGTGPTAMGVAVFAALSVAVLA
MAV_3441|M.avium_104 NVLRAQRAVQMMIGVTLGIGLGTVVQGMLGPGALPIAVAALVALGAAVFI
.. *. : *: .: . . :. :
Mvan_3048|M.vanbaalenii_PYR-1 SG-IGFIAMAAAVTAAAVFLVDIGRPDMPPAVADPVLAVLFGGALALIAH
Mflv_3327|M.gilvum_PYR-GCK SG-VGYIAMSGAVAAAAVFLLDVARAGTPSSLTDPLIATIAGGALAVIAH
MSMEG_3570|M.smegmatis_MC2_155 SR-FGYLAVGVPLGAALMFFLGVGGAAEWSGLADRLVEILIGGGLAVMAH
TH_4065|M.thermoresistible__bu LR-YGFIAVNVALGAALMFVLAIGDTGLPATFTGPVFAVVLGGAVAIMAH
MMAR_2160|M.marinum_M VRGFVAQGLMFVNQTAVSAVLVLVFAPTGDVVAERLFDALIGGGLALVVA
MAV_3441|M.avium_104 GGGFIGHGMMFANQTVVSALLVLALYR-GGAGPERIFDALIGGAVAIVVA
.: :. .: : . :. : **.:*::.
Mvan_3048|M.vanbaalenii_PYR-1 VVLP-DDALTRLSQRAGELLRTEIDYAATVIKAYVHELDDPAETMTSAWQ
Mflv_3327|M.gilvum_PYR-GCK VALP-DDELTRLAQRAGELLKTEIDYAATVIKGYVHERENATEEMTAAWQ
MSMEG_3570|M.smegmatis_MC2_155 VALP-DHALIRLRQRAGELLMTEIDYAAMVVRAFVHEIDHPAEALSAAWQ
TH_4065|M.thermoresistible__bu VALP-DDGLVRLRQRAGELLKTEIDYAALVVKAFVHGVDRPNEVLAAVWQ
MMAR_2160|M.marinum_M MLLFPADPVRILRDARTGALAALHDTLVEVIKFIDNPGGAAPDWLLATFD
MAV_3441|M.avium_104 VLLFPADPRTVLGAARAGVLAVLHDVLSRAADVSSGRRAAPPDWPLSAVD
: * . * * . * . . : :. :
Mvan_3048|M.vanbaalenii_PYR-1 RAFRAR-AAFEATTGAMRMESRELRHWLRSYRTALNAVTSSCTTLEDQLP
Mflv_3327|M.gilvum_PYR-GCK RVSRAR-SAFEATTGAMRLESRDFRLWLRSYRTAINSLTSSCTTLEAHMP
MSMEG_3570|M.smegmatis_MC2_155 RAFRAR-AAFEAAWGAARLDSPTLRRWLRSYRTALNSVTSACTTLENNLP
TH_4065|M.thermoresistible__bu RAFRAR-AAFEAASGMTRVDSRELRRWLRTFRAAVNAVTGACVALETNLP
MMAR_2160|M.marinum_M RLHNQLGGLIEARATAVLVSRRAPRRWAARDAIADIERQSARLGMLVSGV
MAV_3441|M.avium_104 RVHEQLSGLLEARTTARHVVAIAPRRWGLRDAVRAADHQAVHVALLAGSV
* . . :** : * * . :
Mvan_3048|M.vanbaalenii_PYR-1 AQPAVTANREFVLAVDEYVEALRGDPPTAASPWRVDCAELAAAEARLREA
Mflv_3327|M.gilvum_PYR-GCK TRPAG-VDREFAITVDEFVEALCGDPPTAASPWTVDAAELEAAAQRLREA
MSMEG_3570|M.smegmatis_MC2_155 THPSSALHPDFQAAVDDYVTALRGAPPSPAVPWSLDTGELAAALRRVQEV
TH_4065|M.thermoresistible__bu DQPSAKLDREFVAAVDEYIDALRGSPPNPAAAWTVDTAALTAADQKVREV
MMAR_2160|M.marinum_M LNLVRAITRLPEQQVPRPVRIALAELAAALAVADDEPAAAIAHAAAARDR
MAV_3441|M.avium_104 LQLARAVAPGPGDRQGQPVSTVLLVLAAATALADRDPAGACVYLGSARRH
. : . . : . . :
Mvan_3048|M.vanbaalenii_PYR-1 VRRHGPEEGPARLLVAEVDTITRHVSAISVSPSPTSVR--
Mflv_3327|M.gilvum_PYR-GCK APRERAEDGSSRVLVAEATAITRSLTAVAISPVPISAR--
MSMEG_3570|M.smegmatis_MC2_155 ASTLAADNGAARILVGELSTITRSLIGISIDRVTPAGESS
TH_4065|M.thermoresistible__bu AGRLPRDDRAARVLVAELGTITRSLLAVAATREPTSAG--
MMAR_2160|M.marinum_M AQELLS-QARDR-TEVVLADIVDACGVDLQRVIDVPGGDH
MAV_3441|M.avium_104 AARLRSGDGGDREPHVALADAVGACVDDLQRVIDLRPG--
. : * .