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VIMGLTVRSVLPDAAAALRSLAAVGVIAVIAALWGPPGSATSAVAVAAVAGATAFQDSPRSRIPLVYLVS GLCGVAVLLGTAVSGLPVLFLLLCALWCAGVAMLWAHGPNTGLIGAASGALMVAATSAGTPVSVGAALGT AALAVVGGLSQAVVLAVWPPQRWRAQRDAVVAAYRSLAADARRLADGRDDGWAVDTEPLVALREAFTDVS GPTLRRPAVYRGWYALPERIAATLTDMANGPRSEALSRVLEEAADTMAAVADTSRAGRVGTHVSIGRFDS VVTEIDGPESGTVRRLSALLHEVAAMRLGDFVPSTPDAVRLRRPELPTSVRSAMDTVRGHLNQDSPVLRH AVRVGAAVGLGGGIAQYAGIPYGYWIPLTALLVLRPETAHTYTRCVGRVAGTAAGVVVASAVLVPFAPAP VVSLGFAVVAVGIAYLVSGVGYIAMSGAVAAAAVFLLDVARAGTPSSLTDPLIATIAGGALAVIAHVALP DDELTRLAQRAGELLKTEIDYAATVIKGYVHERENATEEMTAAWQRVSRARSAFEATTGAMRLESRDFRL WLRSYRTAINSLTSSCTTLEAHMPTRPAGVDREFAITVDEFVEALCGDPPTAASPWTVDAAELEAAAQRL REAAPRERAEDGSSRVLVAEATAITRSLTAVAISPVPISAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3327 | - | - | 100% (671) | protein of unknown function DUF893, YccS/YhfK |
| M. gilvum PYR-GCK | Mflv_0746 | - | 3e-13 | 23.86% (700) | membrane protein-like protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2149 | - | 2e-05 | 35.09% (114) | hypothetical protein MAB_2149 |
| M. marinum M | MMAR_2160 | - | 5e-06 | 24.60% (313) | transmembrane alanine and valine and leucine rich protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_3570 | - | 1e-144 | 43.71% (668) | hypothetical protein MSMEG_3570 |
| M. thermoresistible (build 8) | TH_4065 | - | 1e-90 | 50.14% (361) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3048 | - | 0.0 | 63.70% (675) | protein of unknown function DUF893, YccS/YhfK |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3327|M.gilvum_PYR-GCK MIMG----LTVRSVLPDAAAALRSLAAVGVIAVIAALWGPPGSATSAVAV
Mvan_3048|M.vanbaalenii_PYR-1 MIKG----LVQRSAMPDPAAVLRSLACVAAVAVVAVQWGPQGSATAVVGA
MSMEG_3570|M.smegmatis_MC2_155 MQTGGPAADALRLSTPDPGAVARSLVGALAMTTAALALASPPAAMWTLGA
TH_4065|M.thermoresistible__bu --------------------------------------------------
MMAR_2160|M.marinum_M --------------------------------------------------
MAB_2149|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3327|M.gilvum_PYR-GCK AAVAGATAFQDSPRSRIPLVYLVSGLCGVAVLLGTAVSGLPVLFLLLCAL
Mvan_3048|M.vanbaalenii_PYR-1 AAVAGATALQDSPRGRVTVVLLVTAVAGLAVLLGALTSGFSPLFVAVATL
MSMEG_3570|M.smegmatis_MC2_155 GVIAGAVALQRSPGGRVPLVVTASLEMAIVVALAVLTGSHDVVFVLAVAV
TH_4065|M.thermoresistible__bu --------------------------------------------------
MMAR_2160|M.marinum_M --------------------------------------------------
MAB_2149|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3327|M.gilvum_PYR-GCK WCAGVAMLWAHGPNTGLIGAASGALMVAATSAG-TPVSVGAA-LGTAALA
Mvan_3048|M.vanbaalenii_PYR-1 WCFGASMLWALGANPGLIGAASAALLVSAPPVTPTPTSV----VVTWLLA
MSMEG_3570|M.smegmatis_MC2_155 WCFAAGMQWSVGANAGLIASAASSLLVIAPPDGYATAPTAFDGLLAPLLV
TH_4065|M.thermoresistible__bu --------------------------------------------------
MMAR_2160|M.marinum_M --------------------------------------------------
MAB_2149|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3327|M.gilvum_PYR-GCK VVGGLSQAVVLAVWPPQRWRAQRDAVVAAYRSLAADARRLADGRDDG-WA
Mvan_3048|M.vanbaalenii_PYR-1 VAGGLLQVWVISLWPPLRWRNQRKALVAAYRSLAADARKISDGTVGGGPA
MSMEG_3570|M.smegmatis_MC2_155 FGAGVLQAVLIATLPPHRWRVQREGLTRAYRSLATDARNVAADRSAD---
TH_4065|M.thermoresistible__bu --------------------------------------------------
MMAR_2160|M.marinum_M --------------------------------------------------
MAB_2149|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3327|M.gilvum_PYR-GCK VDTEPLVALREAFTDVSGPTLRRPAVYRGWYALPERIAATLTDM----AN
Mvan_3048|M.vanbaalenii_PYR-1 ADPEPLAALRTAFTAADGPSRRRPATYRGWYALPERIADTLTDV----AR
MSMEG_3570|M.smegmatis_MC2_155 VDDAPLTWLREVFADS--EAAQRSRANYGGYQVPERIAVTLAELRSAYAE
TH_4065|M.thermoresistible__bu --------------------------------------------------
MMAR_2160|M.marinum_M --------------------------------------------------
MAB_2149|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3327|M.gilvum_PYR-GCK GP-RSEALSRVLEEAADTMAAVADTSRAGRVGTHVSIGRFDSVVTEIDGP
Mvan_3048|M.vanbaalenii_PYR-1 LPARSDALALALAEAADTLAAVADTSRTGRVGADVAIGRFDSVAATVDGS
MSMEG_3570|M.smegmatis_MC2_155 PASDAPGVPRLLAAAAALLDAIADQGHTARRDAEHALVRVDSAVASVDGP
TH_4065|M.thermoresistible__bu ------------------------------------------XAAQVS--
MMAR_2160|M.marinum_M --------------------------------------------------
MAB_2149|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3327|M.gilvum_PYR-GCK ESGTVRRLSALLHEVAAMRLGDFVPSTPDAVRLRRPELPTSVRSAMDTVR
Mvan_3048|M.vanbaalenii_PYR-1 ESVVVQKLSTQLHEAVAMRLGDFVPSTPDAVRLRRPELRTSVRSAVDVMR
MSMEG_3570|M.smegmatis_MC2_155 EKALAQRLGDLLREAAVLRFG----------QLHRPDLIGSLASAPSVVR
TH_4065|M.thermoresistible__bu -------------DAVALRFG----------RLHR----RTPGDVLAAVQ
MMAR_2160|M.marinum_M --------------------------------MEISLLTRAADGSLAAVR
MAB_2149|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3327|M.gilvum_PYR-GCK GHLNQDSPVLRHAVRVGAAVGLGGGIAQYAGIPYGYWIPLTALLVLRPET
Mvan_3048|M.vanbaalenii_PYR-1 SHLDRHSPVLRHAVRLAAAVAVGCVVDRYAEGAYGFWIPLTVLMVLRPET
MSMEG_3570|M.smegmatis_MC2_155 SHLRWTSPILRHAVRLSAATALAAVAARFGGVEHGHWIALTVLVVLRPET
TH_4065|M.thermoresistible__bu AQLTWPSPVLRHALRLAVGTAGAIALARYGDLDQGHWMALTVLLVLRPET
MMAR_2160|M.marinum_M QLRTALWPITQASVTAGLAWFLTHDVLDHP---QPFFAPISAAVCMSATN
MAB_2149|M.abscessus_ATCC_1997 ---MTTYVAAPAMTQAGPSDDLTLVPARKPARSLTGFLSMTGGVLVAALT
. . : .:: : : . .
Mflv_3327|M.gilvum_PYR-GCK AHTYTRCVGRVAGTAAGVVVASAVLVPFAPAPVVSLGFAVVAVGIAYLVS
Mvan_3048|M.vanbaalenii_PYR-1 AHTYTRCVGRVAGTLVGIVTASAVLVILNPGVAVSAVLALAAVGVACVLS
MSMEG_3570|M.smegmatis_MC2_155 AHTYTRCAGRIATLAAGVTVASGLTLMWQPEALPAAACALALVALAYWLS
TH_4065|M.thermoresistible__bu AHTYTRCGGRILGLATGVAVATVPIVLWRPDGLVAATVAALLVAATYLAL
MMAR_2160|M.marinum_M VLRARRAVQMVGGVALGIVVGAGVQAVLGTGPTAMGVAVFAALSVAVLAV
MAB_2149|M.abscessus_ATCC_1997 RPPAVREFFRQAGAIARVSVLPMCMVAIPLAVLIVLVLEALVFGPTGFPT
* : . . .. :
Mflv_3327|M.gilvum_PYR-GCK G-VGYIAMSGAVAAAAVFLLDVARAGTPSSLTDPLIATIAGGALAVIAHV
Mvan_3048|M.vanbaalenii_PYR-1 G-IGFIAMAAAVTAAAVFLVDIGRPDMPPAVADPVLAVLFGGALALIAHV
MSMEG_3570|M.smegmatis_MC2_155 R-FGYLAVGVPLGAALMFFLGVGGAAEWSGLADRLVEILIGGGLAVMAHV
TH_4065|M.thermoresistible__bu R-YGFIAVNVALGAALMFVLAIGDTGLPATFTGPVFAVVLGGAVAIMAHV
MMAR_2160|M.marinum_M RGFVAQGLMFVNQTAVSAVLVLVFAPTGDVVAERLFDALIGGGLALVVAM
MAB_2149|M.abscessus_ATCC_1997 H-------------------------------AVLVAAAAG------ATV
:. * . :
Mflv_3327|M.gilvum_PYR-GCK ALPDDELTRLAQRAGELLKTEIDYAATVIKGYVHERENAT-EEMTAAWQR
Mvan_3048|M.vanbaalenii_PYR-1 VLPDDALTRLSQRAGELLRTEIDYAATVIKAYVHELDDPA-ETMTSAWQR
MSMEG_3570|M.smegmatis_MC2_155 ALPDHALIRLRQRAGELLMTEIDYAAMVVRAFVHEIDHPA-EALSAAWQR
TH_4065|M.thermoresistible__bu ALPDDGLVRLRQRAGELLKTEIDYAALVVKAFVHGVDRPN-EVLAAVWQR
MMAR_2160|M.marinum_M LLFPADPVRILRDARTGALAALHDTLVEVIKFIDNPGGAAPDWLLATFDR
MAB_2149|M.abscessus_ATCC_1997 VFAEADSARIQRDIGAMRSRGIDITHGFVVPRVLATAVAA---VPLAFIA
: *: : :. : : : . : .:
Mflv_3327|M.gilvum_PYR-GCK VSRAR-SAFEATTGAMRLESRDFRLWLR--------SYRTAINSLTSSCT
Mvan_3048|M.vanbaalenii_PYR-1 AFRAR-AAFEATTGAMRMESRELRHWLR--------SYRTALNAVTSSCT
MSMEG_3570|M.smegmatis_MC2_155 AFRAR-AAFEAAWGAARLDSPTLRRWLR--------SYRTALNSVTSACT
TH_4065|M.thermoresistible__bu AFRAR-AAFEAASGMTRVDSRELRRWLR--------TFRAAVNAVTGACV
MMAR_2160|M.marinum_M LHNQLGGLIEARATAVLVSRRAPRRWAARDAIADIERQSARLGMLVSGVL
MAB_2149|M.abscessus_ATCC_1997 VAAAG-VYFFSAFG-----------------------KHTPLSLFIGNLL
: : : :. . .
Mflv_3327|M.gilvum_PYR-GCK TLEAHMPTRPAG-VDREFAITVDEFVEALCGDPPTAASPWTVDAAELEAA
Mvan_3048|M.vanbaalenii_PYR-1 TLEDQLPAQPAVTANREFVLAVDEYVEALRGDPPTAASPWRVDCAELAAA
MSMEG_3570|M.smegmatis_MC2_155 TLENNLPTHPSSALHPDFQAAVDDYVTALRGAPPSPAVPWSLDTGELAAA
TH_4065|M.thermoresistible__bu ALETNLPDQPSAKLDREFVAAVDEYIDALRGSPPNPAAAWTVDTAALTAA
MMAR_2160|M.marinum_M NLVRAITRLPEQQVPRPVRIALAELAAALAVADDEPAAAIAHAAAARDRA
MAB_2149|M.abscessus_ATCC_1997 QLMSPLN-ILIVVIEAASLGLIAGLIACYRGATAT---------------
* : : .
Mflv_3327|M.gilvum_PYR-GCK AQRLREAAPRERAEDGSSRVLVAEATAITRSLTAVAISPVPISAR--
Mvan_3048|M.vanbaalenii_PYR-1 EARLREAVRRHGPEEGPARLLVAEVDTITRHVSAISVSPSPTSVR--
MSMEG_3570|M.smegmatis_MC2_155 LRRVQEVASTLAADNGAARILVGELSTITRSLIGISIDRVTPAGESS
TH_4065|M.thermoresistible__bu DQKVREVAGRLPRDDRAARVLVAELGTITRSLLAVAATREPTSAG--
MMAR_2160|M.marinum_M QELLSQAR------DRTEVVLADIVDACGVDLQRVIDVPGGDH----
MAB_2149|M.abscessus_ATCC_1997 -----------------------------------------------