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VTEIAPGSGACVRANIDAFLKDVGAGAVRDVASVGMRRASVTVVLPTRNEARNLPHVAERMPPVDEIVVI DGGSSDGTADVARELWPHATVIEQTRKGKGNALACGFRAATGDIIVMIDGDGSTDPAEIPRFVDALLGGA DLAKGTRFRGDGGSDDITSFRRIGNLGLNWLVNCLFGTEFSDLCYGYNAFWRRNLECLDLPATDLTAPQW GDGFEIETVINVRAARSGWLIREVNSFEGRRIYGRSNLNAVTDGLRVLRTIRREQRKHRAAAHAVVGAGW SP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2676 | - | - | 100% (282) | glycosyl transferase family protein |
| M. vanbaalenii PYR-1 | Mvan_0217 | - | 1e-50 | 49.56% (228) | glycosyl transferase family protein |
| M. vanbaalenii PYR-1 | Mvan_0886 | - | 4e-21 | 35.35% (215) | glycosyl transferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2077c | ppm1 | 1e-17 | 31.71% (205) | polyprenol-monophosphomannose synthase Ppm1 |
| M. gilvum PYR-GCK | Mflv_3118 | - | 9e-17 | 29.26% (229) | dolichyl-phosphate beta-D-mannosyltransferase |
| M. tuberculosis H37Rv | Rv2051c | ppm1 | 1e-17 | 31.71% (205) | polyprenol-monophosphomannose synthase Ppm1 |
| M. leprae Br4923 | MLBr_01440 | - | 5e-17 | 28.24% (255) | putative glycosyl transferase |
| M. abscessus ATCC 19977 | MAB_2207 | - | 6e-17 | 29.73% (222) | polyprenol phosphate mannosyl transferase 1 |
| M. marinum M | MMAR_0885 | - | 2e-19 | 34.42% (215) | glycosyl transferase - dolichol-P-sugar synthase |
| M. avium 104 | MAV_4605 | - | 5e-22 | 35.51% (214) | glycosyltransferase |
| M. smegmatis MC2 155 | MSMEG_0995 | - | 7e-23 | 34.07% (226) | glycosyl transferase, family protein 2 |
| M. thermoresistible (build 8) | TH_0733 | - | 5e-15 | 30.89% (191) | Polyprenol-monophosphomannose synthase Ppm1 |
| M. ulcerans Agy99 | MUL_0638 | - | 7e-20 | 34.88% (215) | glycosyl transferase - dolichol-P-sugar synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 MKLGAWVAAQLPTTRTAVRTRLTRLVVSIVAGLLLYASFPPRNCWWAAVV
Rv2051c|M.tuberculosis_H37Rv MKLGAWVAAQLPTTRTAVRTRLTRLVVSIVAGLLLYASFPPRNCWWAAVV
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MMAR_0885|M.marinum_M --------------------------------------------------
MUL_0638|M.ulcerans_Agy99 --------------------------------------------------
MAV_4605|M.avium_104 --------------------------------------------------
MSMEG_0995|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2676|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 ALALLAWVLTHRATTPVGGLGYGLLFGLVFYVSLLPWIGELVGPGPWLAL
Rv2051c|M.tuberculosis_H37Rv ALALLAWVLTHRATTPVGGLGYGLLFGLVFYVSLLPWIGELVGPGPWLAL
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MMAR_0885|M.marinum_M --------------------------------------------------
MUL_0638|M.ulcerans_Agy99 --------------------------------------------------
MAV_4605|M.avium_104 --------------------------------------------------
MSMEG_0995|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2676|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 ATTCALFPGIFGLFAVVVRLLPGWPIWFAVGWAAQEWLKSILPFGGFPWG
Rv2051c|M.tuberculosis_H37Rv ATTCALFPGIFGLFAVVVRLLPGWPIWFAVGWAAQEWLKSILPFGGFPWG
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MMAR_0885|M.marinum_M --------------------------------------------------
MUL_0638|M.ulcerans_Agy99 --------------------------------------------------
MAV_4605|M.avium_104 --------------------------------------------------
MSMEG_0995|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2676|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 SVAFGQAEGPLLPLVQLGGVALLSTGVALVGCGLTAIALEIEKWWRTGGQ
Rv2051c|M.tuberculosis_H37Rv SVAFGQAEGPLLPLVQLGGVALLSTGVALVGCGLTAIALEIEKWWRTGGQ
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MMAR_0885|M.marinum_M --------------------------------------------------
MUL_0638|M.ulcerans_Agy99 --------------------------------------------------
MAV_4605|M.avium_104 --------------------------------------------------
MSMEG_0995|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2676|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 GDAPPAVVLPAACICLVLFAAIVVWPQVRHAGSGSGGEPTVTVAVVQGNV
Rv2051c|M.tuberculosis_H37Rv GDAPPAVVLPAACICLVLFAAIVVWPQVRHAGSGSGGEPTVTVAVVQGNV
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MMAR_0885|M.marinum_M --------------------------------------------------
MUL_0638|M.ulcerans_Agy99 --------------------------------------------------
MAV_4605|M.avium_104 --------------------------------------------------
MSMEG_0995|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2676|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 PRLGLDFNAQRRAVLDNHVEETLRLAADVHAGLAQQPQFVIWPENSSDID
Rv2051c|M.tuberculosis_H37Rv PRLGLDFNAQRRAVLDNHVEETLRLAADVHAGLAQQPQFVIWPENSSDID
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MMAR_0885|M.marinum_M --------------------------------------------------
MUL_0638|M.ulcerans_Agy99 --------------------------------------------------
MAV_4605|M.avium_104 --------------------------------------------------
MSMEG_0995|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2676|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 PFVNPDAGQRISAAAEAIGAPILIGTLMDVPGRPRENPEWTNTAIVWNPG
Rv2051c|M.tuberculosis_H37Rv PFVNPDAGQRISAAAEAIGAPILIGTLMDVPGRPRENPEWTNTAIVWNPG
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MMAR_0885|M.marinum_M --------------------------------------------------
MUL_0638|M.ulcerans_Agy99 --------------------------------------------------
MAV_4605|M.avium_104 --------------------------------------------------
MSMEG_0995|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2676|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 TGPADRHDKAIVQPFGEYLPMPWLFRHLSGYADRAGHFVPGNGTGVVRIA
Rv2051c|M.tuberculosis_H37Rv TGPADRHDKAIVQPFGEYLPMPWLFRHLSGYADRAGHFVPGNGTGVVRIA
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MMAR_0885|M.marinum_M --------------------------------------------------
MUL_0638|M.ulcerans_Agy99 --------------------------------------------------
MAV_4605|M.avium_104 --------------------------------------------------
MSMEG_0995|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2676|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 GVPVGVATCWEVIFDRAPRKSILGGAQLLTVPSNNATFNKTMSEQQLAFA
Rv2051c|M.tuberculosis_H37Rv GVPVGVATCWEVIFDRAPRKSILGGAQLLTVPSNNATFNKTMSEQQLAFA
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MMAR_0885|M.marinum_M --------------------------------------------------
MUL_0638|M.ulcerans_Agy99 --------------------------------------------------
MAV_4605|M.avium_104 --------------------------------------------------
MSMEG_0995|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2676|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 KVRAVEHDRYVVVAGTTGISAVIAPDGGELIRTDFFQPAYLDSQVRLKTR
Rv2051c|M.tuberculosis_H37Rv KVRAVEHDRYVVVAGTTGISAVIAPDGGELIRTDFFQPAYLDSQVRLKTR
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MMAR_0885|M.marinum_M --------------------------------------------------
MUL_0638|M.ulcerans_Agy99 --------------------------------------------------
MAV_4605|M.avium_104 --------------------------------------------------
MSMEG_0995|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2676|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 LTPATRWGPILQWILVGAAAAVVLVAMRQNGWFPRPRRSEPKGENDDSDA
Rv2051c|M.tuberculosis_H37Rv LTPATRWGPILQWILVGAAAAVVLVAMRQNGWFPRPRRSEPKGENDDSDA
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MMAR_0885|M.marinum_M --------------------------------------------------
MUL_0638|M.ulcerans_Agy99 --------------------------------------------------
MAV_4605|M.avium_104 --------------------------------------------------
MSMEG_0995|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2676|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK -----------------------------------------MSVPGGVTG
TH_0733|M.thermoresistible__bu --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 PPGRSEASGPPALSESDDELIQPEQGGRHSSGFGRHRATSRSYMTTGQPA
Rv2051c|M.tuberculosis_H37Rv PPGRSEASGPPALSESDDELIQPEQGGRHSSGFGRHRATSRSYMTTGQPA
MLBr_01440|M.leprae_Br4923 -------------------------------------------MITGQPA
MMAR_0885|M.marinum_M --------------------------------------------------
MUL_0638|M.ulcerans_Agy99 --------------------------------------------------
MAV_4605|M.avium_104 --------------------------------------------------
MSMEG_0995|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2676|M.vanbaalenii_PYR-1 ---------------------MTEIAPGSGACVRANIDAFLKDVGAGAVR
Mflv_3118|M.gilvum_PYR-GCK REEPAGRPSARTLVIIPTYNERDNLLSIVSRVNDAAPDVHVLIVDDGSPD
TH_0733|M.thermoresistible__bu --------------------------------------VHVLIVDDGSPD
MAB_2207|M.abscessus_ATCC_1997 MDPVTERPSARTLVIIPTYNERENLPLILGRLHKAQPDVHVLIVDDGSPD
Mb2077c|M.bovis_AF2122/97 PPAPGNRPSQRVLVIIPTFNERENLPVIHRRLTQACPAVHVLVVDDSSPD
Rv2051c|M.tuberculosis_H37Rv PPAPGNRPSQRVLVIIPTFNERENLPVIHRRLTQACPAVHVLVVDDSSPD
MLBr_01440|M.leprae_Br4923 RKISGNRPSQCVLVIIPTFNELENLPVTHGRLKDAYPEIHVLIVDDGSPD
MMAR_0885|M.marinum_M ----MPGET--VTVVLPCLNEAESLPGVLAAIP---GSYRALVVDNNSTD
MUL_0638|M.ulcerans_Agy99 ----MPGET--VTVVLPCLNEAESLPGVLAAIP---GSYRALVVDNNSTD
MAV_4605|M.avium_104 ----MPGADGRVTVVLPCLNEEESLPGVLATIP---PGYRALVVDNNSTD
MSMEG_0995|M.smegmatis_MC2_155 ----MAPRSATVTVVLPCLDEEQSLPAVLAAIP---HGYQALVVDNNSTD
Mvan_2676|M.vanbaalenii_PYR-1 DVASVGMRRASVTVVLPTRNEARNLPHVAERMP---PVDEIVVIDGGSSD
. :::*..*.*
Mflv_3118|M.gilvum_PYR-GCK GTGELADELALGDPDRIHVMHRTSKDGLGAAYLAGFAWGLNREYTVLVEM
TH_0733|M.thermoresistible__bu GTGELADELALADPDRVHVMHRASKAGLGAAYLAGFRWGLNRQYSVLVEM
MAB_2207|M.abscessus_ATCC_1997 GTGELADEAALADPDRVHVMHRKEKGGLGAAYIAGFGWGLARQYSVLVEM
Mb2077c|M.bovis_AF2122/97 GTGQLADELAQADPGRTHVMHRTAKNGLGAAYLAGFAWGLSREYSVLVEM
Rv2051c|M.tuberculosis_H37Rv GTGQLADELAQADPGRTHVMHRTAKNGLGAAYLAGFAWGLSREYSVLVEM
MLBr_01440|M.leprae_Br4923 GTGELADELAQVDPGCTHVMHRTTKDGLGTAYLAGFAWGMSRDYSVLVEM
MMAR_0885|M.marinum_M DTAAVAARHG-------AEVVAEAQPGYGAAVHAGVVAAKT---PIVAVI
MUL_0638|M.ulcerans_Agy99 DTAAVAARHG-------AEVVAESQPGYGAAVHAGVVAAKT---PIVAVI
MAV_4605|M.avium_104 DTAGVARRHG-------AQVVTETRAGYGAAVHAGVLAATT---PIVAVL
MSMEG_0995|M.smegmatis_MC2_155 RTAEVARAHG-------AVVVHEPRPGYGSAVHAGVLAAQT---PVVAVL
Mvan_2676|M.vanbaalenii_PYR-1 GTADVARELWPH-----ATVIEQTRKGKGNALACGFRAATG---DIIVMI
*. :* : : * * * .*. . ::. :
Mflv_3118|M.gilvum_PYR-GCK DADGSHAPEDLHRLLAEIDAGADVVIGSRYVEGGDVRNWPRRRMVLSRTA
TH_0733|M.thermoresistible__bu DADGSHAPEELHRLLDAVDAGADLAIGSRYVDGGQVRNWPRRRLLLSRTA
MAB_2207|M.abscessus_ATCC_1997 DADGSHAPEQLSRLLDAVDAGADLAIGSRYVPGGTVVNWPWRRLVLSRSA
Mb2077c|M.bovis_AF2122/97 DADGSHAPEQLQRLLDAVDAGADLAIGSRYVAGGTVRNWPWRRLVLSKTA
Rv2051c|M.tuberculosis_H37Rv DADGSHAPEQLQRLLDAVDAGADLAIGSRYVAGGTVRNWPWRRLVLSKTA
MLBr_01440|M.leprae_Br4923 DADGSHAPEQLHRLLGAVDAGADLAIGSRYVNGGTVRNWPWQRLALSKTA
MMAR_0885|M.marinum_M DADGSMDPADLPRLVAELDRGADLVTGRRRPIPG--LHWPWVARIGTVVM
MUL_0638|M.ulcerans_Agy99 DADGSMDPADLPRLVAELDRGADLVTGRRRPIPG--LHWPWVARIGTVVM
MAV_4605|M.avium_104 DADGSMDGADLPRLVAALEAGADLVTGRRRPVRG--LRWPWVARVGTVVM
MSMEG_0995|M.smegmatis_MC2_155 DGDGSLDPAALPALVSALDDGADMVIGRRRPVAG--LRWPWHARLGTAAV
Mvan_2676|M.vanbaalenii_PYR-1 DGDGSTDPAEIPRFVDALLGGADLAKGTRFRGDGGSDDITSFRRIGNLGL
*.*** : :: : ***:. * * * . .
Mflv_3118|M.gilvum_PYR-GCK NAYSRILLGVDIHDITAGYRAYRREVLEKIDLAAVDSKG------YGFQV
TH_0733|M.thermoresistible__bu NTYSRLLLGVDIRDITAGYRAYRREVLEKIDLDAVDSKG------YCFQI
MAB_2207|M.abscessus_ATCC_1997 NVYARLVLGVKPHDITAGYRAYRREVLEKLDLGAVESHG------YCFQI
Mb2077c|M.bovis_AF2122/97 NTYSRLALGIGIHDITAGYRAYRREALEAIDLDGVDSKG------YCFQI
Rv2051c|M.tuberculosis_H37Rv NTYSRLALGIGIHDITAGYRAYRREALEAIDLDGVDSKG------YCFQI
MLBr_01440|M.leprae_Br4923 NKYSRLALGIDVHDITAGYRAYRREVLEAIDLDSVASKG------YCFQI
MMAR_0885|M.marinum_M SWRLRTRHGLPVHDIAP---MRVARRDALLALGVVDRRS-----GYPLEL
MUL_0638|M.ulcerans_Agy99 SWRLRTRHGLPVHDIAP---MRVARRDVLLALGVVDRRS-----GYPLEL
MAV_4605|M.avium_104 SWRLRTRHGLPVHDIAP---MRVARRDALLGLGVADRRS-----GYPLEL
MSMEG_0995|M.smegmatis_MC2_155 CWRLRRRYGLPVHDIAP---MRVARREALLDLGVTDRRS-----GYPLEL
Mvan_2676|M.vanbaalenii_PYR-1 NWLVNCLFGTEFSDLCYGYNAFWRRNLECLDLPATDLTAPQWGDGFEIET
. * *: . : * . . : ::
Mflv_3118|M.gilvum_PYR-GCK DLTWRSINAGFTVVEVPITFTEREHGVS---KMDGSTIREAIIKVAQWGM
TH_0733|M.thermoresistible__bu DLTWRAINHGFKVVEVPITFTERELGQS---KMSGSNIREAIFKVAEWGI
MAB_2207|M.abscessus_ATCC_1997 DLTLRTIAHGFEVAEVPITFTERAIGES---KMSGSIINEALVKVTKWGV
Mb2077c|M.bovis_AF2122/97 DLTWRTVSNGFVVTEVPITFTERELGVS---KMSGSNIREALVKVARWGI
Rv2051c|M.tuberculosis_H37Rv DLTWRTVSNGFVVTEVPITFTERELGVS---KMSGSNIREALVKVARWGI
MLBr_01440|M.leprae_Br4923 DLTWRTVNNGFVIIEVPITFTEREFGLS---KMSGSNIREALVKVTRWGI
MMAR_0885|M.marinum_M LV--RAAAAGWRVAEFDVSYGPRTGGKS---KVSGSLRGSMIAILDFWKV
MUL_0638|M.ulcerans_Agy99 LV--RAAAAGWRVAEFDVSYGPRTGGKS---KVSGSLRGSMIAILDFWKV
MAV_4605|M.avium_104 LV--RAAAAGWRVVELDVRYGPRTGGKS---KVSGSLRGSITAILDFWKV
MSMEG_0995|M.smegmatis_MC2_155 LV--RAAQAGWRVVEHDVTYGARTGGRS---KVSGSLRGSVIAAVDFWRA
Mvan_2676|M.vanbaalenii_PYR-1 VINVRAARSGWLIREVNSFEGRRIYGRSNLNAVTDGLRVLRTIRREQRKH
: *: *: : * * * * : ..
Mflv_3118|M.gilvum_PYR-GCK RARIDRARGNTP---------------------
TH_0733|M.thermoresistible__bu RGRLDRARGIVR---------------------
MAB_2207|M.abscessus_ATCC_1997 QSRLDRARGVNR---------------------
Mb2077c|M.bovis_AF2122/97 EGRLSRSDHARARPDIARPGAGGSRVSRADVTE
Rv2051c|M.tuberculosis_H37Rv EGRLSRSDHARARPDIARPGAGGSRVSRADVTE
MLBr_01440|M.leprae_Br4923 DGRIQRARTGRAYNSVSRGGGTGSSPSAP----
MMAR_0885|M.marinum_M IS-------------------------------
MUL_0638|M.ulcerans_Agy99 IS-------------------------------
MAV_4605|M.avium_104 IS-------------------------------
MSMEG_0995|M.smegmatis_MC2_155 I--------------------------------
Mvan_2676|M.vanbaalenii_PYR-1 RAAAHAVVGAGWSP-------------------