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TAPPSPRPAAAVHIADLARPTFSPEAQAIIDGMAAMADYCPLTADALHEQASIQTGLTDFGAQDYRERMA VLLEAFHELPRLTASGRTYAFSLMLTFLKGRLQVIDHLKRHPEVFDVDIAAPMIIAGLPRTGTTHLHSML AADPALRSLPYWEAQEPLPPLGEEGTIEPRRERTGAALNISNTLMPYFQLMHEMTIDHIHEDIGLMVQDF ASGFFTTLTHLPRWSDYLRDNDQTPGYQFLRMMLQVLSHQDGYERRWVLKSPQHLEQFVPIMNVFPDATF IVTHRDPVDVSVSMATMMTYTMRMSVDEVDVPTVAGYWIDRIDEMLSACLRDHDKLPPERTIDVRFDEFM ADDLAMVERVWDVAGYRPSAESRTAVSEYLAGHTRGRLGTVDYRAADLGLDSDELRRRFTPYIERFVH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2230 | - | - | 100% (419) | hypothetical protein Mvan_2230 |
| M. vanbaalenii PYR-1 | Mvan_1960 | - | e-109 | 48.88% (403) | hypothetical protein Mvan_1960 |
| M. vanbaalenii PYR-1 | Mvan_2268 | - | 5e-45 | 33.77% (379) | hypothetical protein Mvan_2268 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3559c | - | 6e-39 | 31.54% (371) | hypothetical protein Mb3559c |
| M. gilvum PYR-GCK | Mflv_4115 | - | 0.0 | 90.66% (407) | hypothetical protein Mflv_4115 |
| M. tuberculosis H37Rv | Rv3529c | - | 6e-39 | 31.54% (371) | hypothetical protein Rv3529c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3968 | - | 6e-44 | 29.11% (371) | putative sulfotransferase |
| M. marinum M | MMAR_0341 | - | 1e-106 | 49.10% (387) | hypothetical protein MMAR_0341 |
| M. avium 104 | MAV_5164 | - | 1e-118 | 51.35% (407) | hypothetical protein MAV_5164 |
| M. smegmatis MC2 155 | MSMEG_5930 | - | 2e-48 | 34.41% (372) | hypothetical protein MSMEG_5930 |
| M. thermoresistible (build 8) | TH_0375 | - | 1e-37 | 30.11% (372) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4363 | - | 7e-65 | 33.81% (420) | hypothetical protein MUL_4363 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2230|M.vanbaalenii_PYR-1 MTAPPSPRPAAAVHIADLARPTFSPEAQAIIDGMAAMADYCPLTADALHE
Mflv_4115|M.gilvum_PYR-GCK ----------MAVHITDLARPTFTPQAQVIIDGMAAMAPYCPLTAEALHE
MMAR_0341|M.marinum_M --------------------------------MMAALAPDCSLDSDALHA
MAV_5164|M.avium_104 ----------MTVRLEDLAEPQFSAEGQQILDMMAAMAPQCPLDADALHA
MUL_4363|M.ulcerans_Agy99 --MEPSSTDIADIDFDDLTRPVLTDVQRQVLQFTESR--HVEFDIAALLA
Mb3559c|M.bovis_AF2122/97 -----------MTRRPDRKDVATVDELHASATKLVGLDDFGTDDDNYR--
Rv3529c|M.tuberculosis_H37Rv -----------MTRRPDRKDVATVDELHASATKLVGLDDFGTDDDNYR--
MSMEG_5930|M.smegmatis_MC2_155 --------------------MGTVEDLHASATKATGLDDFGTDDDNYR--
TH_0375|M.thermoresistible__bu -----------MTPR---TDVGTVEDLHASAVKACGLEDFGSDDDNYK--
MAB_3968|M.abscessus_ATCC_1997 -----------MRAGFKAARPWPIRALNRVGNPLTGIGAAPTLDTQWLRS
.
Mvan_2230|M.vanbaalenii_PYR-1 QASIQTGL-TDFGAQD-YRERMAVLLEAFHELPRLTASGRTYAFSLMLTF
Mflv_4115|M.gilvum_PYR-GCK QASAQTGL-TDFGDQG-YRERMSVLLQAFEELPGLTSFGRTYAFSLMLTF
MMAR_0341|M.marinum_M KASADTGL-HDFGDDD-YRERLDVYLAALAEIDGMQPAGVVNFYGQLLQL
MAV_5164|M.avium_104 QASADTGL-HDFGPDD-YRERLEVYLTALREIDGLHAAGTVNFYGQLLQI
MUL_4363|M.ulcerans_Agy99 EAVDQAGVGDDLGDTDGFGNRLRAHVAAIEGDQGLTQLTRSSLRQRVVRL
Mb3559c|M.bovis_AF2122/97 -------------------EALGVLLDAYQGEAGLTVLGSKMNRFFLRGA
Rv3529c|M.tuberculosis_H37Rv -------------------EALGVLLDAYQGEAGLTVLGSKMNRFFLRGA
MSMEG_5930|M.smegmatis_MC2_155 -------------------EALGVLLESYQRDAHLTELGSKMSRFFLRNA
TH_0375|M.thermoresistible__bu -------------------EALAVLLDSYQREADLTELGSKMSRFFLRNA
MAB_3968|M.abscessus_ATCC_1997 AARRATGL--EWVADAYLDDALEVLAASLRNDAKLSFLGRKMVQVRLVGM
: : . : : :
Mvan_2230|M.vanbaalenii_PYR-1 LKGRLQVIDHLKRHPEVFDVDIAAPMIIAGLPRTGTTHLHSMLAADPALR
Mflv_4115|M.gilvum_PYR-GCK LKGRLQVVDHLKRYPEVFDIDIAAPMIIAGLPRTGTTHLHSMLAADPALR
MMAR_0341|M.marinum_M LKNRLLLSELRHRHPEIDDIELQPPVVIAGLPRTGTTHLHNMLAAPTTFR
MAV_5164|M.avium_104 LKNRLLLTDLLKRHPEIHDIELRSPVVIAGLPRTGTTHLHNLLAAPPTFR
MUL_4363|M.ulcerans_Agy99 LRNRLSLTDLIRRYPEIESIRIEKPFVVVGMPRSGTTHLVNLLAADPRRR
Mb3559c|M.bovis_AF2122/97 LVARLLSQSAWKQYPEHVDVAIKRPIFVTGLVRTGTTALHRLLGADPAHQ
Rv3529c|M.tuberculosis_H37Rv LVARLLSQSAWKQYPEHVDVAIKRPIFVTGLVRTGTTALHRLLGADPAHQ
MSMEG_5930|M.smegmatis_MC2_155 LVARLLSEASWKANPQYADVEIERPIFVTGLPRTGTTVLHRLLTADPAHQ
TH_0375|M.thermoresistible__bu LVARLVSEAAWKQYPQHADVVIERPIFVTGLPRTGTTALHRLLAADPAHQ
MAB_3968|M.abscessus_ATCC_1997 LSTRLRLRELIRKNPGIAQLPVEPPIVIVGLQRTGTTLLHRLLAADPSAG
* ** : * .: : *..:.*: *:*** * :* * .
Mvan_2230|M.vanbaalenii_PYR-1 SLPYWEAQEPLPPLGE--EGT-IEPRRERTGAALNISNTLMPYFQLMHEM
Mflv_4115|M.gilvum_PYR-GCK SLPYWEAQEPLPPPGE--EGT-IEPRRQRTGDALNISNTLMPYFQLMHEM
MMAR_0341|M.marinum_M TMPYWESVEPFPLPQE--AGVEPDPRLVRMDVAVGVINTVMPHFALMHEM
MAV_5164|M.avium_104 TMPYWESVEPFPMPNE--VGVQPDPRRTRMDVAVAVINTVMPHFALMHEM
MUL_4363|M.ulcerans_Agy99 ALPYWESQDPIPARGQGPDIFGVDPRYTRAKTEHDALMATAPVVAAMHDR
Mb3559c|M.bovis_AF2122/97 GLHMWLAEYPQPRPPR--ETWESNPLYRQLDAQFTQHHAENPGYTGLHFM
Rv3529c|M.tuberculosis_H37Rv GLHMWLAEYPQPRPPR--ETWESNPLYRQLDAQFTQHHAENPGYTGLHFM
MSMEG_5930|M.smegmatis_MC2_155 GLEMWLAEFPQPRPPR--ETWPDNPVYQQLAASFSQHHQENPDYTGLHFM
TH_0375|M.thermoresistible__bu GLELWLAEFPQPRPPR--ETWPDNPIYRQLEAQFTKAHQENPDYTGLHFM
MAB_3968|M.abscessus_ATCC_1997 SMSSWEGASPLPHPEQ--PSGAPDLRIAQAAKDERSLRYLAPQFFAIHSV
: * . * * . : : * :*
Mvan_2230|M.vanbaalenii_PYR-1 TIDHIHEDIGLMVQDFASGFFTTLTHLPRWSDYLRDNDQTPGYQFLRMML
Mflv_4115|M.gilvum_PYR-GCK TVDHIHEDIGLMVQDFSSGFFTTLTHLPRWSDYLRDHDQTPGYQFLRMML
MMAR_0341|M.marinum_M TADHVHEEIQLLANDFSTMLFETLGHVPRWRDYYETHDQTPHYQYLATQL
MAV_5164|M.avium_104 TTDHVHEEIQLLANDVSTMLLETLAEVPRWRAYYQAHDQTPHYEYLATQL
MUL_4363|M.ulcerans_Agy99 FPEAIEEEVELLDLDLASYVLEWHARVPDWRDYYLGLDQRRHYAYLKKVL
Mb3559c|M.bovis_AF2122/97 AAYELEECWQLLRQSLHSVSYEALAHVPSYADWLSRQDWTPSYCRHRRNL
Rv3529c|M.tuberculosis_H37Rv AAYELEECWQLLRQSLHSVSYEALAHVPSYADWLSRQDWTPSYCRHRRNL
MSMEG_5930|M.smegmatis_MC2_155 TADEVEECWQLLRQSLHSVSYETLAHLPTYANWLAQQDWTRPYQRHRRNL
TH_0375|M.thermoresistible__bu TAGEVEECWQLLRQSVHSVSYETLAHVPSYARWLARQDWTKPYQRHRRNL
MAB_3968|M.abscessus_ATCC_1997 EAEAPEEDVLLLDFALHSQMPEVMFHVPGYAKWLADQDMTPAYELHRLLL
.* *: . : .:* : : * * *
Mvan_2230|M.vanbaalenii_PYR-1 QVLSHQDGYERRWVLKSPQHLEQFVPIMNVFPDATFIVTHRDPVDVSVSM
Mflv_4115|M.gilvum_PYR-GCK QVLSHQDGSTRRWVLKSPQHLEQFVPIMNVFPDATFIVTHRDPVDVSVSM
MMAR_0341|M.marinum_M KAMQFLRG-GRRWLLKSPQHLEQVPVLDRVFPGSIVLFTHRDPVPVALSM
MAV_5164|M.avium_104 RAMQFLRG-GRRWLLKSPQHLEQVPVLDRVFPDSIVVFTHRDPVPVALSM
MUL_4363|M.ulcerans_Agy99 QALTFLRG-PQTWVLKRPQHCEQLGPLMATFPDATVAFTHRDPVAVIQST
Mb3559c|M.bovis_AF2122/97 QLIGLNDA-EKRWVLKNPSHLFALDALMATYPDALVVQTHRPVETIMASM
Rv3529c|M.tuberculosis_H37Rv QLIGLNDA-EKRWVLKNPSHLFALDALMATYPDALVVQTHRPVETIMASM
MSMEG_5930|M.smegmatis_MC2_155 QLIGLNDA-EKRWVLKNPSHLFALDALFATYPDALVIQCHRPAETIMASM
TH_0375|M.thermoresistible__bu QLIGLNDV-EKRWVLKNPSHLFALDALFATYPDALVVQCHRPAETIMASM
MAB_3968|M.abscessus_ATCC_1997 QVLQWQQP-RGRWVLKTPAHLEHLDVLLRVYPGAVVVWTHRDPAQTTASS
: : *:** * * . : .:*.: . ** *
Mvan_2230|M.vanbaalenii_PYR-1 ATMMTYTMRMSVDEVDVPTVAGYWIDRIDEMLSACLRDHDKLPPERTIDV
Mflv_4115|M.gilvum_PYR-GCK ATMMTYTMRMSVDEVDVPTVAGYWIDRIDEMLSACLRDHDKLPAERTIDV
MMAR_0341|M.marinum_M LAMITYSARMHRWPVPVEQIAHYWVDRLDRMLATLVRDRDTIGPERSIDI
MAV_5164|M.avium_104 IAMITYSARMHRSPVPVRQIAESWIDRLGQMLAALVRDRDVIGPDRSIDI
MUL_4363|M.ulcerans_Agy99 ITMMAYSDRLRRTSIDAGWLLDYWSDRVYPLLWACVRDRDIVPPDRSIDI
Mb3559c|M.bovis_AF2122/97 CSLAQHTTEGWSTKFVGAQIGADAMDTWSRGLERFNAARAKYDSAQFYDV
Rv3529c|M.tuberculosis_H37Rv CSLAQHTTEGWSTKFVGAQIGADAMDTWSRGLERFNAARAKYDSAQFYDV
MSMEG_5930|M.smegmatis_MC2_155 CSLSAHTTAGWSNTFVGAQIGADAMDTWARGLEAFTAERAKHDPAQFLDV
TH_0375|M.thermoresistible__bu CSLSQHTTAGWSNTFVGAQIGADAMETWTRGLRLFNEARANYDPAQFHDV
MAB_3968|M.abscessus_ATCC_1997 SSMLAHYQALFSDRVDHHELARYWLGKNAQIIDRAIAVRAEHP-AAFVDI
:: : . : : : *:
Mvan_2230|M.vanbaalenii_PYR-1 RFDEFMADDLAMVERVWDVAGYRPSAESRTAVSEYLAGHTRGRLGTVDYR
Mflv_4115|M.gilvum_PYR-GCK RFDEFMADDLAMVQRVWDTAGYTPSDESRAAVAEYLAGHTRGRLGTVDYR
MMAR_0341|M.marinum_M RFDDFMADEVGVAERIYALAGEPFTDSVRTATAGYLAGHQRGRLGAVQTS
MAV_5164|M.avium_104 RFDDFMADELGVAERVYALADEPFTDDARAAVADYLAGHRRGRLGNVETS
MUL_4363|M.ulcerans_Agy99 GFHQLNGNEMALLDELYRCSGVAITPKVRGLFQQYLDGNPRGKHGRVRYH
Mb3559c|M.bovis_AF2122/97 DYHDLIADPLGTVADIYRHFGLTLSDEARQAMTTVHAESQSGARAPKHSY
Rv3529c|M.tuberculosis_H37Rv DYHDLIADPLGTVADIYRHFGLTLSDEARQAMTTVHAESQSGARAPKHSY
MSMEG_5930|M.smegmatis_MC2_155 DYDDFVADPLATVESVYRHFGMPYTDAARAAVTEVYEASRRGPRAPKHTY
TH_0375|M.thermoresistible__bu EYADFVKDPIGTVEGIYRHFGLEFTDAARDAMTRLHTESQRGPRAPRHSY
MAB_3968|M.abscessus_ATCC_1997 NYTELLDDPIAAVQRIYHAADRRLSDDALTAMRVSLQQNRQHKHG-EHRY
: :: : :. :: . : .
Mvan_2230|M.vanbaalenii_PYR-1 AA-DLGLDSDELRRRFTPYIERFVH-----------
Mflv_4115|M.gilvum_PYR-GCK AE-DLGVDRDELRRRFAPYVERFVR-----------
MMAR_0341|M.marinum_M CE-MFGLTEESLRERFAPYLKRFLG-----------
MAV_5164|M.avium_104 YE-MFGLDEDSLRERFAPYVERFLA-----------
MUL_4363|M.ulcerans_Agy99 LQRHFGSSAEQLRERFDFYFDRFDVRPE--------
Mb3559c|M.bovis_AF2122/97 SLADYGLTVEMVKERFAGL-----------------
Rv3529c|M.tuberculosis_H37Rv SLADYGLTVEMVKERFAGL-----------------
MSMEG_5930|M.smegmatis_MC2_155 SLADYGLTSEAVKERFTGL-----------------
TH_0375|M.thermoresistible__bu SLADYGLTAESVRDAFSGL-----------------
MAB_3968|M.abscessus_ATCC_1997 SLAQFGLTIAEVDAAYRRYIDHFAIQTERGGVRGDR
* : :