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TDTTDGFIHLDDLAEPRYSPAAQQLREMMATLAADCPLDTDILHARAREATGLDDFGPQDYRERLDRYVA ELREIDMHGPGIVNFHAQLVQWLKNRLLLTDLLARHPEIEDIELVAPVVIAGLPRSGTTHLHNMLASAPT FRSLPYWESVEPFPLPAEAGIEPDPRVGRMDVAVQTMDLLMPHFALMHEMTTDHVHEEIQLLANDFSTML MDTLAHVPRWTDYFWSTDQTSSYRYLVTQLKALQFLRGGRRWILKSPQHLGQLPVLDEVMPGVVVVFTHR DPVPVALSMIAMVTYSERMHRDKVDVPTVARAWVDRLEHLLNACVRDRDIIPTERSADITFDAFMADEIG TAERVYRVAGEPLTEESRSAIGRYLDGHRRGRHGRVYTSAEMFGLDPEELRDRFTPYMGWMRNRPARCSQ AKVTSALG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1960 | - | - | 100% (429) | hypothetical protein Mvan_1960 |
| M. vanbaalenii PYR-1 | Mvan_2230 | - | e-109 | 48.88% (403) | hypothetical protein Mvan_2230 |
| M. vanbaalenii PYR-1 | Mvan_2324 | - | 8e-41 | 32.36% (377) | hypothetical protein Mvan_2324 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3559c | - | 4e-33 | 28.88% (374) | hypothetical protein Mb3559c |
| M. gilvum PYR-GCK | Mflv_4385 | - | 0.0 | 79.68% (379) | hypothetical protein Mflv_4385 |
| M. tuberculosis H37Rv | Rv3529c | - | 4e-33 | 28.88% (374) | hypothetical protein Rv3529c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3968 | - | 7e-48 | 29.55% (396) | putative sulfotransferase |
| M. marinum M | MMAR_0341 | - | 1e-154 | 69.11% (382) | hypothetical protein MMAR_0341 |
| M. avium 104 | MAV_5164 | - | 1e-161 | 67.41% (402) | hypothetical protein MAV_5164 |
| M. smegmatis MC2 155 | MSMEG_5930 | - | 2e-40 | 29.11% (371) | hypothetical protein MSMEG_5930 |
| M. thermoresistible (build 8) | TH_0375 | - | 2e-33 | 29.79% (376) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4363 | - | 2e-75 | 39.81% (422) | hypothetical protein MUL_4363 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1960|M.vanbaalenii_PYR-1 --MTDTTDGFIHLDDLAEPRYSPAAQQLREMMATLAADCPLDTDILHARA
Mflv_4385|M.gilvum_PYR-GCK -------------------------------MASLAADCPLDAEVLHTRA
MMAR_0341|M.marinum_M ------------------------------MMAALAPDCSLDSDALHAKA
MAV_5164|M.avium_104 --------MTVRLEDLAEPQFSAEGQQILDMMAAMAPQCPLDADALHAQA
MUL_4363|M.ulcerans_Agy99 MEPSSTDIADIDFDDLTRPVLTDVQRQV--LQFTESRHVEFDIAALLAEA
Mb3559c|M.bovis_AF2122/97 ------------------------------MTRRPDRKDVATVDELHASA
Rv3529c|M.tuberculosis_H37Rv ------------------------------MTRRPDRKDVATVDELHASA
MSMEG_5930|M.smegmatis_MC2_155 ---------------------------------------MGTVEDLHASA
TH_0375|M.thermoresistible__bu ------------------------------MTPR---TDVGTVEDLHASA
MAB_3968|M.abscessus_ATCC_1997 ------------------------------MRAGFKAARPWPIRALNRVG
* .
Mvan_1960|M.vanbaalenii_PYR-1 REATGL-DDFGPQD-YR-------------------ERLDRYVAELREID
Mflv_4385|M.gilvum_PYR-GCK REATGL-DDFGPDD-YR-------------------ERLEMYLAELREID
MMAR_0341|M.marinum_M SADTGL-HDFGDDD-YR-------------------ERLDVYLAALAEID
MAV_5164|M.avium_104 SADTGL-HDFGPDD-YR-------------------ERLEVYLTALREID
MUL_4363|M.ulcerans_Agy99 VDQAGVGDDLGDTDGFG-------------------NRLRAHVAAIEGDQ
Mb3559c|M.bovis_AF2122/97 TKLVGLDDFGTDDDNYR-------------------EALGVLLDAYQGEA
Rv3529c|M.tuberculosis_H37Rv TKLVGLDDFGTDDDNYR-------------------EALGVLLDAYQGEA
MSMEG_5930|M.smegmatis_MC2_155 TKATGLDDFGTDDDNYR-------------------EALGVLLESYQRDA
TH_0375|M.thermoresistible__bu VKACGLEDFGSDDDNYK-------------------EALAVLLDSYQREA
MAB_3968|M.abscessus_ATCC_1997 NPLTGIGAAPTLDTQWLRSAARRATGLEWVADAYLDDALEVLAASLRNDA
*: : : *
Mvan_1960|M.vanbaalenii_PYR-1 -MHGPGIVNFHAQLVQWLKNRLLLTDLLARHPEIEDIELVAPVVIAGLPR
Mflv_4385|M.gilvum_PYR-GCK -MHAPGVVNFHVQLVQWLKNRLLLTDLLTRHPEIEEIELLPPVVIAGLPR
MMAR_0341|M.marinum_M GMQPAGVVNFYGQLLQLLKNRLLLSELRHRHPEIDDIELQPPVVIAGLPR
MAV_5164|M.avium_104 GLHAAGTVNFYGQLLQILKNRLLLTDLLKRHPEIHDIELRSPVVIAGLPR
MUL_4363|M.ulcerans_Agy99 GLTQLTRSSLRQRVVRLLRNRLSLTDLIRRYPEIESIRIEKPFVVVGMPR
Mb3559c|M.bovis_AF2122/97 GLTVLGSKMNRFFLRGALVARLLSQSAWKQYPEHVDVAIKRPIFVTGLVR
Rv3529c|M.tuberculosis_H37Rv GLTVLGSKMNRFFLRGALVARLLSQSAWKQYPEHVDVAIKRPIFVTGLVR
MSMEG_5930|M.smegmatis_MC2_155 HLTELGSKMSRFFLRNALVARLLSEASWKANPQYADVEIERPIFVTGLPR
TH_0375|M.thermoresistible__bu DLTELGSKMSRFFLRNALVARLVSEAAWKQYPQHADVVIERPIFVTGLPR
MAB_3968|M.abscessus_ATCC_1997 KLSFLGRKMVQVRLVGMLSTRLRLRELIRKNPGIAQLPVEPPIVIVGLQR
: : * ** * .: : *..:.*: *
Mvan_1960|M.vanbaalenii_PYR-1 SGTTHLHNMLASAPTFRSLPYWESVEPFPLPAEAG--IEPDPRVGRMDVA
Mflv_4385|M.gilvum_PYR-GCK SGTTHLHNLLAAAPTFRSLPYWESVEPFPLPAEQG--VEPDPRIGRMDLA
MMAR_0341|M.marinum_M TGTTHLHNMLAAPTTFRTMPYWESVEPFPLPQEAG--VEPDPRLVRMDVA
MAV_5164|M.avium_104 TGTTHLHNLLAAPPTFRTMPYWESVEPFPMPNEVG--VQPDPRRTRMDVA
MUL_4363|M.ulcerans_Agy99 SGTTHLVNLLAADPRRRALPYWESQDPIPARGQGPDIFGVDPRYTRAKTE
Mb3559c|M.bovis_AF2122/97 TGTTALHRLLGADPAHQGLHMWLAEYPQPRPPRET--WESNPLYRQLDAQ
Rv3529c|M.tuberculosis_H37Rv TGTTALHRLLGADPAHQGLHMWLAEYPQPRPPRET--WESNPLYRQLDAQ
MSMEG_5930|M.smegmatis_MC2_155 TGTTVLHRLLTADPAHQGLEMWLAEFPQPRPPRET--WPDNPVYQQLAAS
TH_0375|M.thermoresistible__bu TGTTALHRLLAADPAHQGLELWLAEFPQPRPPRET--WPDNPIYRQLEAQ
MAB_3968|M.abscessus_ATCC_1997 TGTTLLHRLLAADPSAGSMSSWEGASPLPHPEQPS--GAPDLRIAQAAKD
:*** * .:* : . : * . * * . : :
Mvan_1960|M.vanbaalenii_PYR-1 VQTMDLLMPHFALMHEMTTDHVHEEIQLLANDFSTMLMDTLAHVPRWTDY
Mflv_4385|M.gilvum_PYR-GCK LQTMDLLMPHFALMHEMTTDHAHEEIQLLANDFSTMLMETLAHVPRWTEY
MMAR_0341|M.marinum_M VGVINTVMPHFALMHEMTADHVHEEIQLLANDFSTMLFETLGHVPRWRDY
MAV_5164|M.avium_104 VAVINTVMPHFALMHEMTTDHVHEEIQLLANDVSTMLLETLAEVPRWRAY
MUL_4363|M.ulcerans_Agy99 HDALMATAPVVAAMHDRFPEAIEEEVELLDLDLASYVLEWHARVPDWRDY
Mb3559c|M.bovis_AF2122/97 FTQHHAENPGYTGLHFMAAYELEECWQLLRQSLHSVSYEALAHVPSYADW
Rv3529c|M.tuberculosis_H37Rv FTQHHAENPGYTGLHFMAAYELEECWQLLRQSLHSVSYEALAHVPSYADW
MSMEG_5930|M.smegmatis_MC2_155 FSQHHQENPDYTGLHFMTADEVEECWQLLRQSLHSVSYETLAHLPTYANW
TH_0375|M.thermoresistible__bu FTKAHQENPDYTGLHFMTAGEVEECWQLLRQSVHSVSYETLAHVPSYARW
MAB_3968|M.abscessus_ATCC_1997 ERSLRYLAPQFFAIHSVEAEAPEEDVLLLDFALHSQMPEVMFHVPGYAKW
* :* . .* ** . : : .:* : :
Mvan_1960|M.vanbaalenii_PYR-1 FWSTDQTSSYRYLVTQLKALQFLRGGRRWILKSPQHLGQLPVLDEVMPGV
Mflv_4385|M.gilvum_PYR-GCK YWNRDQTPTYEYLVTQLKALQFLRGGGRWVLKSPQHLAQLPVIGRVLPGV
MMAR_0341|M.marinum_M YETHDQTPHYQYLATQLKAMQFLRGGRRWLLKSPQHLEQVPVLDRVFPGS
MAV_5164|M.avium_104 YQAHDQTPHYEYLATQLRAMQFLRGGRRWLLKSPQHLEQVPVLDRVFPDS
MUL_4363|M.ulcerans_Agy99 YLGLDQRRHYAYLKKVLQALTFLRGPQTWVLKRPQHCEQLGPLMATFPDA
Mb3559c|M.bovis_AF2122/97 LSRQDWTPSYCRHRRNLQLIGLNDAEKRWVLKNPSHLFALDALMATYPDA
Rv3529c|M.tuberculosis_H37Rv LSRQDWTPSYCRHRRNLQLIGLNDAEKRWVLKNPSHLFALDALMATYPDA
MSMEG_5930|M.smegmatis_MC2_155 LAQQDWTRPYQRHRRNLQLIGLNDAEKRWVLKNPSHLFALDALFATYPDA
TH_0375|M.thermoresistible__bu LARQDWTKPYQRHRRNLQLIGLNDVEKRWVLKNPSHLFALDALFATYPDA
MAB_3968|M.abscessus_ATCC_1997 LADQDMTPAYELHRLLLQVLQWQQPRGRWVLKTPAHLEHLDVLLRVYPGA
* * *: : *:** * * : : . *.
Mvan_1960|M.vanbaalenii_PYR-1 VVVFTHRDPVPVALSMIAMVTYSERMHRDKVDVPTVARAWVDRLEHLLNA
Mflv_4385|M.gilvum_PYR-GCK RVVFTHRDPVPVALSMIAMVTYSARMHRDHVDVPVVAAAWVDRLEKLLDA
MMAR_0341|M.marinum_M IVLFTHRDPVPVALSMLAMITYSARMHRWPVPVEQIAHYWVDRLDRMLAT
MAV_5164|M.avium_104 IVVFTHRDPVPVALSMIAMITYSARMHRSPVPVRQIAESWIDRLGQMLAA
MUL_4363|M.ulcerans_Agy99 TVAFTHRDPVAVIQSTITMMAYSDRLRRTSIDAGWLLDYWSDRVYPLLWA
Mb3559c|M.bovis_AF2122/97 LVVQTHRPVETIMASMCSLAQHTTEGWSTKFVGAQIGADAMDTWSRGLER
Rv3529c|M.tuberculosis_H37Rv LVVQTHRPVETIMASMCSLAQHTTEGWSTKFVGAQIGADAMDTWSRGLER
MSMEG_5930|M.smegmatis_MC2_155 LVIQCHRPAETIMASMCSLSAHTTAGWSNTFVGAQIGADAMDTWARGLEA
TH_0375|M.thermoresistible__bu LVVQCHRPAETIMASMCSLSQHTTAGWSNTFVGAQIGADAMETWTRGLRL
MAB_3968|M.abscessus_ATCC_1997 VVVWTHRDPAQTTASSSSMLAHYQALFSDRVDHHELARYWLGKNAQIIDR
* ** * :: : . : :
Mvan_1960|M.vanbaalenii_PYR-1 CVRDRDIIPTERSADITFDAFMADEIGTAERVYRVAGEPLTEESRSAIGR
Mflv_4385|M.gilvum_PYR-GCK CVRDREVIAPDRSLDVRFDDFMADELGVAESIYALTGEDFDGRSRAAVAQ
MMAR_0341|M.marinum_M LVRDRDTIGPERSIDIRFDDFMADEVGVAERIYALAGEPFTDSVRTATAG
MAV_5164|M.avium_104 LVRDRDVIGPDRSIDIRFDDFMADELGVAERVYALADEPFTDDARAAVAD
MUL_4363|M.ulcerans_Agy99 CVRDRDIVPPDRSIDIGFHQLNGNEMALLDELYRCSGVAITPKVRGLFQQ
Mb3559c|M.bovis_AF2122/97 FNAARAKYDSAQFYDVDYHDLIADPLGTVADIYRHFGLTLSDEARQAMTT
Rv3529c|M.tuberculosis_H37Rv FNAARAKYDSAQFYDVDYHDLIADPLGTVADIYRHFGLTLSDEARQAMTT
MSMEG_5930|M.smegmatis_MC2_155 FTAERAKHDPAQFLDVDYDDFVADPLATVESVYRHFGMPYTDAARAAVTE
TH_0375|M.thermoresistible__bu FNEARANYDPAQFHDVEYADFVKDPIGTVEGIYRHFGLEFTDAARDAMTR
MAB_3968|M.abscessus_ATCC_1997 AIAVRAEHP-AAFVDINYTELLDDPIAAVQRIYHAADRRLSDDALTAMRV
* *: : : : :. :* .
Mvan_1960|M.vanbaalenii_PYR-1 YLDGHRRGRHGRVYTSAE-MFGLDPEELRDRFTPYMGWMRNRPARCSQAK
Mflv_4385|M.gilvum_PYR-GCK YLQSHRRGRHGRVHTSAD-MFGLDPEELRERFAPYS------------AR
MMAR_0341|M.marinum_M YLAGHQRGRLGAVQTSCE-MFGLTEESLRERFAPYL------------KR
MAV_5164|M.avium_104 YLAGHRRGRLGNVETSYE-MFGLDEDSLRERFAPYV------------ER
MUL_4363|M.ulcerans_Agy99 YLDGNPRGKHGRVRYHLQRHFGSSAEQLRERFDFYF------------DR
Mb3559c|M.bovis_AF2122/97 VHAESQSGARAPKHSYSLADYGLTVEMVKERFAGL---------------
Rv3529c|M.tuberculosis_H37Rv VHAESQSGARAPKHSYSLADYGLTVEMVKERFAGL---------------
MSMEG_5930|M.smegmatis_MC2_155 VYEASRRGPRAPKHTYSLADYGLTSEAVKERFTGL---------------
TH_0375|M.thermoresistible__bu LHTESQRGPRAPRHSYSLADYGLTAESVRDAFSGL---------------
MAB_3968|M.abscessus_ATCC_1997 SLQQNRQHKHG-EHRYSLAQFGLTIAEVDAAYRRYI------------DH
. :* : :
Mvan_1960|M.vanbaalenii_PYR-1 VTSALG--------
Mflv_4385|M.gilvum_PYR-GCK FLS-----------
MMAR_0341|M.marinum_M FLG-----------
MAV_5164|M.avium_104 FLA-----------
MUL_4363|M.ulcerans_Agy99 FDVRPE--------
Mb3559c|M.bovis_AF2122/97 --------------
Rv3529c|M.tuberculosis_H37Rv --------------
MSMEG_5930|M.smegmatis_MC2_155 --------------
TH_0375|M.thermoresistible__bu --------------
MAB_3968|M.abscessus_ATCC_1997 FAIQTERGGVRGDR