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TAGRFDPDRLVEQACAAAGLDDFGDDGSWRDGLHRLCDGLVADARLNDLGVEIAAMDIHRALTSRLAIVD WRARHPAIGAAPVPRPIFIVGQPRTGTTILFDLLAQDPALRPPLTWEVDNPFPPPEPETYDTDPRIAQTQ ANIEMSEQIVPGLLAHHPMGALVGQECVRITAGQFTSMIFPTQYRLPDYYRWLLYDADHGPAYRYHRMFL QHLQSGVGGRWLLKSPAHLWQLDALVAEYPDALIVQTHRDPLNVISSISALLHHLRRLASDESSIPDCAA QSREQIIVGLQRAMALRDSGALAAHQVVDVHFADFMRDPFETLRTLYRRLGRELDPVTEQRMRAHLAEHP GDHGGGRYRWADTGLDAAEVRDQVRAYQQRYDVPDEPLR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2268 | - | - | 100% (390) | hypothetical protein Mvan_2268 |
| M. vanbaalenii PYR-1 | Mvan_2324 | - | 1e-49 | 39.26% (349) | hypothetical protein Mvan_2324 |
| M. vanbaalenii PYR-1 | Mvan_2230 | - | 4e-45 | 33.77% (379) | hypothetical protein Mvan_2230 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3559c | - | 2e-42 | 32.44% (373) | hypothetical protein Mb3559c |
| M. gilvum PYR-GCK | Mflv_4074 | - | 0.0 | 80.72% (389) | hypothetical protein Mflv_4074 |
| M. tuberculosis H37Rv | Rv3529c | - | 2e-42 | 32.44% (373) | hypothetical protein Rv3529c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3968 | - | 2e-46 | 33.59% (387) | putative sulfotransferase |
| M. marinum M | MMAR_0220 | - | 1e-159 | 69.23% (390) | hypothetical protein MMAR_0220 |
| M. avium 104 | MAV_5269 | - | 1e-160 | 69.95% (386) | hypothetical protein MAV_5269 |
| M. smegmatis MC2 155 | MSMEG_5930 | - | 2e-43 | 33.42% (368) | hypothetical protein MSMEG_5930 |
| M. thermoresistible (build 8) | TH_0375 | - | 2e-45 | 34.71% (363) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4091 | - | 3e-45 | 33.16% (374) | hypothetical protein MUL_4091 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5930|M.smegmatis_MC2_155 -------------------------MGTVEDLHASATKATGLDDFGTD--
TH_0375|M.thermoresistible__bu -------------------MTPRTDVGTVEDLHASAVKACGLEDFGSD--
Mb3559c|M.bovis_AF2122/97 ----------------MTRRPDRKDVATVDELHASATKLVGLDDFGTD--
Rv3529c|M.tuberculosis_H37Rv ----------------MTRRPDRKDVATVDELHASATKLVGLDDFGTD--
MUL_4091|M.ulcerans_Agy99 -------------------MADRTDVGTVDELHASATKLVGLDDFGSD--
MAB_3968|M.abscessus_ATCC_1997 MRAGFKAARPWPIRALNRVGNPLTGIGAAPTLDTQWLRSAARRATGLEWV
Mvan_2268|M.vanbaalenii_PYR-1 ---------------------MTAGRFDPDRLVEQACAAAGLDDFGDDGS
Mflv_4074|M.gilvum_PYR-GCK -----------------------MNRFAPEQLIVRACEATGLDDFGDDDT
MMAR_0220|M.marinum_M -------------------MSMPQDRFKPERLIATACEEAGSDDFGADG-
MAV_5269|M.avium_104 -------------------MSL-QDRFAPERLIAAACEEAGSDDFGAEG-
* . * :
MSMEG_5930|M.smegmatis_MC2_155 -DDNYREALGVLLESYQRDAHLTELGSKMSRFFLRNALVARLLSEASWKA
TH_0375|M.thermoresistible__bu -DDNYKEALAVLLDSYQREADLTELGSKMSRFFLRNALVARLVSEAAWKQ
Mb3559c|M.bovis_AF2122/97 -DDNYREALGVLLDAYQGEAGLTVLGSKMNRFFLRGALVARLLSQSAWKQ
Rv3529c|M.tuberculosis_H37Rv -DDNYREALGVLLDAYQGEAGLTVLGSKMNRFFLRGALVARLLSQSAWKQ
MUL_4091|M.ulcerans_Agy99 -QDTYREALEVLLDSYRREAGLTVLGSKMNRFFLRGALVARLLSEAAWKQ
MAB_3968|M.abscessus_ATCC_1997 ADAYLDDALEVLAASLRNDAKLSFLGRKMVQVRLVGMLSTRLRLRELIRK
Mvan_2268|M.vanbaalenii_PYR-1 ----WRDGLHRLCDGLVADARLNDLGVEIAAMDIHRALTSRLAIVDWRAR
Mflv_4074|M.gilvum_PYR-GCK ----WRDGLDLVCDGLTTDARLNEIGVEIAAADLHRALTSRLHIVGWRTQ
MMAR_0220|M.marinum_M ----WQDGLQRVTDALIHEARLSAIGVEIAHLDLMRALRNRLGVIAWRRQ
MAV_5269|M.avium_104 ----WRPGLHRLTDGLINDARLSDIGVEIAHLDIMRALKNRLNVIAWRKA
.* : . :* *. :* :: : * **
MSMEG_5930|M.smegmatis_MC2_155 NPQYADVEIERPIFVTGLPRTGTTVLHRLLTADPAHQGLEMWLAEFPQPR
TH_0375|M.thermoresistible__bu YPQHADVVIERPIFVTGLPRTGTTALHRLLAADPAHQGLELWLAEFPQPR
Mb3559c|M.bovis_AF2122/97 YPEHVDVAIKRPIFVTGLVRTGTTALHRLLGADPAHQGLHMWLAEYPQPR
Rv3529c|M.tuberculosis_H37Rv YPEHVDVAIKRPIFVTGLVRTGTTALHRLLGADPAHQGLHMWLAEYPQPR
MUL_4091|M.ulcerans_Agy99 YPQYAEVPIQRPIFVTGLVRTGTTALHRLLGADPAHQGLHMWLAEFPQPR
MAB_3968|M.abscessus_ATCC_1997 NPGIAQLPVEPPIVIVGLQRTGTTLLHRLLAADPSAGSMSSWEGASPLPH
Mvan_2268|M.vanbaalenii_PYR-1 HPAIGAAPVPRPIFIVGQPRTGTTILFDLLAQDPALRPPLTWEVDNPFPP
Mflv_4074|M.gilvum_PYR-GCK HPEIAAAPVARPIFIVGQPRTGTTILFDLLAQDPALRPPLTWEVDNPFPL
MMAR_0220|M.marinum_M HPEIATKAIDQPIVIVGQPRTGTTILYDLLAQDPDLRAPLTWEVDAPCPV
MAV_5269|M.avium_104 HPEVAEQKISAPIFIVGQPRTGTTILYDLLAQDPALRAPLTWEVDEPCPV
* : **.:.* ***** *. ** ** * * *
MSMEG_5930|M.smegmatis_MC2_155 PPRETWPDNPVYQQLAASFSQHHQENPDYTGLHFMTADEVEECWQLLRQS
TH_0375|M.thermoresistible__bu PPRETWPDNPIYRQLEAQFTKAHQENPDYTGLHFMTAGEVEECWQLLRQS
Mb3559c|M.bovis_AF2122/97 PPRETWESNPLYRQLDAQFTQHHAENPGYTGLHFMAAYELEECWQLLRQS
Rv3529c|M.tuberculosis_H37Rv PPRETWESNPLYRQLDAQFTQHHAENPGYTGLHFMAAYELEECWQLLRQS
MUL_4091|M.ulcerans_Agy99 PPRETWETNPFYRQLDAQLTQHRKDNTGYTGLHFMAAYELEECWQLLRQS
MAB_3968|M.abscessus_ATCC_1997 PEQPSGAPDLRIAQAAKDERSLRYLAPQFFAIHSVEAEAPEEDVLLLDFA
Mvan_2268|M.vanbaalenii_PYR-1 PEPETYDTDPRIAQTQANIEMSEQIVPGLLAHHPMGALVGQECVRITAGQ
Mflv_4074|M.gilvum_PYR-GCK PRLDTYTSDPRIAQTQASIEMSEQIVPGLLGHHPMGALVGQECVRIVAGQ
MMAR_0220|M.marinum_M PAPETYLSDPRIAQTQASIELSEQIIPGFLSFHPMGAQVGQECVRITASE
MAV_5269|M.avium_104 PRPETYHDDPRIARTQAGIDLSEQIMPGFLAFHPMGALVGQECVRITAAE
* : : : . . . * : * :* :
MSMEG_5930|M.smegmatis_MC2_155 LHSVSYETLAHLPTYANWLA-QQDWTRPYQRHRRNLQLIGLNDAEK--RW
TH_0375|M.thermoresistible__bu VHSVSYETLAHVPSYARWLA-RQDWTKPYQRHRRNLQLIGLNDVEK--RW
Mb3559c|M.bovis_AF2122/97 LHSVSYEALAHVPSYADWLS-RQDWTPSYCRHRRNLQLIGLNDAEK--RW
Rv3529c|M.tuberculosis_H37Rv LHSVSYEALAHVPSYADWLS-RQDWTPSYCRHRRNLQLIGLNDAEK--RW
MUL_4091|M.ulcerans_Agy99 LHSVSYETLAHLPSYAQWLA-KQDWTPSYQRHRKNLQLIGLNDAEK--RW
MAB_3968|M.abscessus_ATCC_1997 LHSQMPEVMFHVPGYAKWLA-DQDMTPAYELHRLLLQVLQWQQPRG--RW
Mvan_2268|M.vanbaalenii_PYR-1 FTSMIFPTQYRLPDYYRWLLYDADHGPAYRYHRMFLQHLQSGVGG---RW
Mflv_4074|M.gilvum_PYR-GCK FCSMIYPTQYRMPDYYRWLLYKADHGPAYRYHRMFLQHLQSGVGGPSCQW
MMAR_0220|M.marinum_M FTSMIYSVQYRLPSYYRWLLYEADHRGAYRFHRIFLQHLQSGVAG---QW
MAV_5269|M.avium_104 FVSMIFSVQYRLPNYYRWLLYEADHAGAYRFHRIFLQHLQSGVPG---QW
. * . ::* * ** * .* ** ** : :*
MSMEG_5930|M.smegmatis_MC2_155 VLKNPSHLFALDALFATYPDALVIQCHRPAETIMASMCSLSAHTTAGWSN
TH_0375|M.thermoresistible__bu VLKNPSHLFALDALFATYPDALVVQCHRPAETIMASMCSLSQHTTAGWSN
Mb3559c|M.bovis_AF2122/97 VLKNPSHLFALDALMATYPDALVVQTHRPVETIMASMCSLAQHTTEGWST
Rv3529c|M.tuberculosis_H37Rv VLKNPSHLFALDALMATYPDALVVQTHRPVETIMASMCSLAQHTTEGWST
MUL_4091|M.ulcerans_Agy99 VLKNPSHLFALDALMASYPDALVIQTHRPVETIMASMCSLAQHTSEGWST
MAB_3968|M.abscessus_ATCC_1997 VLKTPAHLEHLDVLLRVYPGAVVVWTHRDPAQTTASSSSMLAHYQALFSD
Mvan_2268|M.vanbaalenii_PYR-1 LLKSPAHLWQLDALVAEYPDALIVQTHRDPLNVISSISALLHHLRRLASD
Mflv_4074|M.gilvum_PYR-GCK LLKSPAHLWQLEALLAEYPDALIVQTHRDPLNVIASISALLHHLRRLASD
MMAR_0220|M.marinum_M LLKSPAHLWQLDALLAEYPDALIVQTHRDPLNVISSIAALTHHLRRMASD
MAV_5269|M.avium_104 LLKSPAHLWQLDALLAEYPDALIVQTHRDPLNVISSIAALTHHLRGMCSD
:**.*:** *:.*. **.*::: ** :* .:: * *
MSMEG_5930|M.smegmatis_MC2_155 TFVGAQIGADAMDTWARGLEAFTAER--AKHDPAQFLDVDYDDFVADPLA
TH_0375|M.thermoresistible__bu TFVGAQIGADAMETWTRGLRLFNEAR--ANYDPAQFHDVEYADFVKDPIG
Mb3559c|M.bovis_AF2122/97 KFVGAQIGADAMDTWSRGLERFNAAR--AKYDSAQFYDVDYHDLIADPLG
Rv3529c|M.tuberculosis_H37Rv KFVGAQIGADAMDTWSRGLERFNAAR--AKYDSAQFYDVDYHDLIADPLG
MUL_4091|M.ulcerans_Agy99 NFVGAQIGADAMETWSRGLQPFDSAR--TNYDPAQFYDVDYRDLIADPMG
MAB_3968|M.abscessus_ATCC_1997 RVDHHELARYWLGKNAQIIDRAIAVR--AEHP-AAFVDINYTELLDDPIA
Mvan_2268|M.vanbaalenii_PYR-1 ESSIPDCAAQSREQIIVGLQRAMALRDSGALAAHQVVDVHFADFMRDPFE
Mflv_4074|M.gilvum_PYR-GCK DSSIPECAAQSREQIVAGLEYAVRLRDSGVPAANQIVDVHFRDFMRDPFE
MMAR_0220|M.marinum_M ESSIAECAAQCYEEIVVGLDREMALRAGGALPAGQVIDVLYTDFINDPWS
MAV_5269|M.avium_104 ESSITECAAQSYEEIVVGLDREMALRDRGAVPPGRVIDVRYADFMKDPWT
: . : * . *: : ::: **
MSMEG_5930|M.smegmatis_MC2_155 TVESVYRHFGMPYTDAARAAVTEVYEASRRGPRAPKHTYSLADYGLTSEA
TH_0375|M.thermoresistible__bu TVEGIYRHFGLEFTDAARDAMTRLHTESQRGPRAPRHSYSLADYGLTAES
Mb3559c|M.bovis_AF2122/97 TVADIYRHFGLTLSDEARQAMTTVHAESQSGARAPKHSYSLADYGLTVEM
Rv3529c|M.tuberculosis_H37Rv TVADIYRHFGLTLSDEARQAMTTVHAESQSGARAPKHSYSLADYGLTVEM
MUL_4091|M.ulcerans_Agy99 TVADIYRHFGLTLTDEARAAMAKIHAESQTGERAPKHRYSLADYGLTAEA
MAB_3968|M.abscessus_ATCC_1997 AVQRIYHAADRRLSDDALTAMRVSLQQNRQHKHG-EHRYSLAQFGLTIAE
Mvan_2268|M.vanbaalenii_PYR-1 TLRTLYRRLGRELDPVTEQRMRAHLAEHPG--DHGGGRYRWADTGLDAAE
Mflv_4074|M.gilvum_PYR-GCK TIRALYARLGRELEPVAEQRMRDFLAAHPG--DHAGNRYRWADTGLDAAE
MMAR_0220|M.marinum_M TIRGVYRKLGRELAPETEQRMRDFLRAHPG--DGGRGRYTWSDTGLDASV
MAV_5269|M.avium_104 TIKDIYERLDRELRPDAEQRMREFLASHPS--DGGRSRYTWSDTGLDAGA
:: :* . : : * :: **
MSMEG_5930|M.smegmatis_MC2_155 VKERFTGL-----------------
TH_0375|M.thermoresistible__bu VRDAFSGL-----------------
Mb3559c|M.bovis_AF2122/97 VKERFAGL-----------------
Rv3529c|M.tuberculosis_H37Rv VKERFAGL-----------------
MUL_4091|M.ulcerans_Agy99 VKERFAGF-----------------
MAB_3968|M.abscessus_ATCC_1997 VDAAYRRYIDHFAIQTERGGVRGDR
Mvan_2268|M.vanbaalenii_PYR-1 VRDQVRAYQQRYDVPDEPLR-----
Mflv_4074|M.gilvum_PYR-GCK VRAQVRTYQERFGVPDEVLR-----
MMAR_0220|M.marinum_M VRDRVRPYQDRYGVPTEQLR-----
MAV_5269|M.avium_104 VRERVRAYQDRYGVPTEALR-----
*