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MMAALAPDCSLDSDALHAKASADTGLHDFGDDDYRERLDVYLAALAEIDGMQPAGVVNFYGQLLQLLKNR LLLSELRHRHPEIDDIELQPPVVIAGLPRTGTTHLHNMLAAPTTFRTMPYWESVEPFPLPQEAGVEPDPR LVRMDVAVGVINTVMPHFALMHEMTADHVHEEIQLLANDFSTMLFETLGHVPRWRDYYETHDQTPHYQYL ATQLKAMQFLRGGRRWLLKSPQHLEQVPVLDRVFPGSIVLFTHRDPVPVALSMLAMITYSARMHRWPVPV EQIAHYWVDRLDRMLATLVRDRDTIGPERSIDIRFDDFMADEVGVAERIYALAGEPFTDSVRTATAGYLA GHQRGRLGAVQTSCEMFGLTEESLRERFAPYLKRFLG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0341 | - | - | 100% (387) | hypothetical protein MMAR_0341 |
| M. marinum M | MMAR_5290 | - | 4e-72 | 40.42% (381) | hypothetical protein MMAR_5290 |
| M. marinum M | MMAR_5017 | - | 6e-39 | 29.92% (371) | hypothetical protein MMAR_5017 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3559c | - | 1e-37 | 30.35% (369) | hypothetical protein Mb3559c |
| M. gilvum PYR-GCK | Mflv_4385 | - | 1e-155 | 69.09% (385) | hypothetical protein Mflv_4385 |
| M. tuberculosis H37Rv | Rv3529c | - | 1e-37 | 30.35% (369) | hypothetical protein Rv3529c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3968 | - | 1e-47 | 29.74% (380) | putative sulfotransferase |
| M. avium 104 | MAV_5164 | - | 0.0 | 82.12% (386) | hypothetical protein MAV_5164 |
| M. smegmatis MC2 155 | MSMEG_5930 | - | 1e-43 | 30.60% (366) | hypothetical protein MSMEG_5930 |
| M. thermoresistible (build 8) | TH_0375 | - | 1e-37 | 29.70% (367) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4363 | - | 3e-71 | 39.90% (381) | hypothetical protein MUL_4363 |
| M. vanbaalenii PYR-1 | Mvan_1960 | - | 1e-154 | 69.11% (382) | hypothetical protein Mvan_1960 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0341|M.marinum_M ------------------------------MMAALAPDCSLDSDALHAKA
MAV_5164|M.avium_104 --------MTVRLEDLAEPQFSAEGQQILDMMAAMAPQCPLDADALHAQA
Mflv_4385|M.gilvum_PYR-GCK -------------------------------MASLAADCPLDAEVLHTRA
Mvan_1960|M.vanbaalenii_PYR-1 --MTDTTDGFIHLDDLAEPRYSPAAQQLREMMATLAADCPLDTDILHARA
MUL_4363|M.ulcerans_Agy99 MEPSSTDIADIDFDDLTRPVLTDVQRQV--LQFTESRHVEFDIAALLAEA
Mb3559c|M.bovis_AF2122/97 ------------------------------MTRRPDRKDVATVDELHASA
Rv3529c|M.tuberculosis_H37Rv ------------------------------MTRRPDRKDVATVDELHASA
MSMEG_5930|M.smegmatis_MC2_155 ---------------------------------------MGTVEDLHASA
TH_0375|M.thermoresistible__bu ------------------------------MTPR---TDVGTVEDLHASA
MAB_3968|M.abscessus_ATCC_1997 ------------------------------MRAGFKAARPWPIRALNRVG
* .
MMAR_0341|M.marinum_M SADTGL-HDFGDDD-YR-------------------ERLDVYLAALAEID
MAV_5164|M.avium_104 SADTGL-HDFGPDD-YR-------------------ERLEVYLTALREID
Mflv_4385|M.gilvum_PYR-GCK REATGL-DDFGPDD-YR-------------------ERLEMYLAELREID
Mvan_1960|M.vanbaalenii_PYR-1 REATGL-DDFGPQD-YR-------------------ERLDRYVAELREID
MUL_4363|M.ulcerans_Agy99 VDQAGVGDDLGDTDGFG-------------------NRLRAHVAAIEGDQ
Mb3559c|M.bovis_AF2122/97 TKLVGLDDFGTDDDNYR-------------------EALGVLLDAYQGEA
Rv3529c|M.tuberculosis_H37Rv TKLVGLDDFGTDDDNYR-------------------EALGVLLDAYQGEA
MSMEG_5930|M.smegmatis_MC2_155 TKATGLDDFGTDDDNYR-------------------EALGVLLESYQRDA
TH_0375|M.thermoresistible__bu VKACGLEDFGSDDDNYK-------------------EALAVLLDSYQREA
MAB_3968|M.abscessus_ATCC_1997 NPLTGIGAAPTLDTQWLRSAARRATGLEWVADAYLDDALEVLAASLRNDA
*: : : *
MMAR_0341|M.marinum_M GMQPAGVVNFYGQLLQLLKNRLLLSELRHRHPEIDDIELQPPVVIAGLPR
MAV_5164|M.avium_104 GLHAAGTVNFYGQLLQILKNRLLLTDLLKRHPEIHDIELRSPVVIAGLPR
Mflv_4385|M.gilvum_PYR-GCK -MHAPGVVNFHVQLVQWLKNRLLLTDLLTRHPEIEEIELLPPVVIAGLPR
Mvan_1960|M.vanbaalenii_PYR-1 -MHGPGIVNFHAQLVQWLKNRLLLTDLLARHPEIEDIELVAPVVIAGLPR
MUL_4363|M.ulcerans_Agy99 GLTQLTRSSLRQRVVRLLRNRLSLTDLIRRYPEIESIRIEKPFVVVGMPR
Mb3559c|M.bovis_AF2122/97 GLTVLGSKMNRFFLRGALVARLLSQSAWKQYPEHVDVAIKRPIFVTGLVR
Rv3529c|M.tuberculosis_H37Rv GLTVLGSKMNRFFLRGALVARLLSQSAWKQYPEHVDVAIKRPIFVTGLVR
MSMEG_5930|M.smegmatis_MC2_155 HLTELGSKMSRFFLRNALVARLLSEASWKANPQYADVEIERPIFVTGLPR
TH_0375|M.thermoresistible__bu DLTELGSKMSRFFLRNALVARLVSEAAWKQYPQHADVVIERPIFVTGLPR
MAB_3968|M.abscessus_ATCC_1997 KLSFLGRKMVQVRLVGMLSTRLRLRELIRKNPGIAQLPVEPPIVIVGLQR
: : * ** * .: : *..:.*: *
MMAR_0341|M.marinum_M TGTTHLHNMLAAPTTFRTMPYWESVEPFPLPQEAG--VEPDPRLVRMDVA
MAV_5164|M.avium_104 TGTTHLHNLLAAPPTFRTMPYWESVEPFPMPNEVG--VQPDPRRTRMDVA
Mflv_4385|M.gilvum_PYR-GCK SGTTHLHNLLAAAPTFRSLPYWESVEPFPLPAEQG--VEPDPRIGRMDLA
Mvan_1960|M.vanbaalenii_PYR-1 SGTTHLHNMLASAPTFRSLPYWESVEPFPLPAEAG--IEPDPRVGRMDVA
MUL_4363|M.ulcerans_Agy99 SGTTHLVNLLAADPRRRALPYWESQDPIPARGQGPDIFGVDPRYTRAKTE
Mb3559c|M.bovis_AF2122/97 TGTTALHRLLGADPAHQGLHMWLAEYPQPRPPRET--WESNPLYRQLDAQ
Rv3529c|M.tuberculosis_H37Rv TGTTALHRLLGADPAHQGLHMWLAEYPQPRPPRET--WESNPLYRQLDAQ
MSMEG_5930|M.smegmatis_MC2_155 TGTTVLHRLLTADPAHQGLEMWLAEFPQPRPPRET--WPDNPVYQQLAAS
TH_0375|M.thermoresistible__bu TGTTALHRLLAADPAHQGLELWLAEFPQPRPPRET--WPDNPIYRQLEAQ
MAB_3968|M.abscessus_ATCC_1997 TGTTLLHRLLAADPSAGSMSSWEGASPLPHPEQPS--GAPDLRIAQAAKD
:*** * .:* : . : * . * * . : :
MMAR_0341|M.marinum_M VGVINTVMPHFALMHEMTADHVHEEIQLLANDFSTMLFETLGHVPRWRDY
MAV_5164|M.avium_104 VAVINTVMPHFALMHEMTTDHVHEEIQLLANDVSTMLLETLAEVPRWRAY
Mflv_4385|M.gilvum_PYR-GCK LQTMDLLMPHFALMHEMTTDHAHEEIQLLANDFSTMLMETLAHVPRWTEY
Mvan_1960|M.vanbaalenii_PYR-1 VQTMDLLMPHFALMHEMTTDHVHEEIQLLANDFSTMLMDTLAHVPRWTDY
MUL_4363|M.ulcerans_Agy99 HDALMATAPVVAAMHDRFPEAIEEEVELLDLDLASYVLEWHARVPDWRDY
Mb3559c|M.bovis_AF2122/97 FTQHHAENPGYTGLHFMAAYELEECWQLLRQSLHSVSYEALAHVPSYADW
Rv3529c|M.tuberculosis_H37Rv FTQHHAENPGYTGLHFMAAYELEECWQLLRQSLHSVSYEALAHVPSYADW
MSMEG_5930|M.smegmatis_MC2_155 FSQHHQENPDYTGLHFMTADEVEECWQLLRQSLHSVSYETLAHLPTYANW
TH_0375|M.thermoresistible__bu FTKAHQENPDYTGLHFMTAGEVEECWQLLRQSVHSVSYETLAHVPSYARW
MAB_3968|M.abscessus_ATCC_1997 ERSLRYLAPQFFAIHSVEAEAPEEDVLLLDFALHSQMPEVMFHVPGYAKW
* :* . .* ** . : : .:* : :
MMAR_0341|M.marinum_M YETHDQTPHYQYLATQLKAMQFLRGGRRWLLKSPQHLEQVPVLDRVFPGS
MAV_5164|M.avium_104 YQAHDQTPHYEYLATQLRAMQFLRGGRRWLLKSPQHLEQVPVLDRVFPDS
Mflv_4385|M.gilvum_PYR-GCK YWNRDQTPTYEYLVTQLKALQFLRGGGRWVLKSPQHLAQLPVIGRVLPGV
Mvan_1960|M.vanbaalenii_PYR-1 FWSTDQTSSYRYLVTQLKALQFLRGGRRWILKSPQHLGQLPVLDEVMPGV
MUL_4363|M.ulcerans_Agy99 YLGLDQRRHYAYLKKVLQALTFLRGPQTWVLKRPQHCEQLGPLMATFPDA
Mb3559c|M.bovis_AF2122/97 LSRQDWTPSYCRHRRNLQLIGLNDAEKRWVLKNPSHLFALDALMATYPDA
Rv3529c|M.tuberculosis_H37Rv LSRQDWTPSYCRHRRNLQLIGLNDAEKRWVLKNPSHLFALDALMATYPDA
MSMEG_5930|M.smegmatis_MC2_155 LAQQDWTRPYQRHRRNLQLIGLNDAEKRWVLKNPSHLFALDALFATYPDA
TH_0375|M.thermoresistible__bu LARQDWTKPYQRHRRNLQLIGLNDVEKRWVLKNPSHLFALDALFATYPDA
MAB_3968|M.abscessus_ATCC_1997 LADQDMTPAYELHRLLLQVLQWQQPRGRWVLKTPAHLEHLDVLLRVYPGA
* * *: : *:** * * : : . *.
MMAR_0341|M.marinum_M IVLFTHRDPVPVALSMLAMITYSARMHRWPVPVEQIAHYWVDRLDRMLAT
MAV_5164|M.avium_104 IVVFTHRDPVPVALSMIAMITYSARMHRSPVPVRQIAESWIDRLGQMLAA
Mflv_4385|M.gilvum_PYR-GCK RVVFTHRDPVPVALSMIAMVTYSARMHRDHVDVPVVAAAWVDRLEKLLDA
Mvan_1960|M.vanbaalenii_PYR-1 VVVFTHRDPVPVALSMIAMVTYSERMHRDKVDVPTVARAWVDRLEHLLNA
MUL_4363|M.ulcerans_Agy99 TVAFTHRDPVAVIQSTITMMAYSDRLRRTSIDAGWLLDYWSDRVYPLLWA
Mb3559c|M.bovis_AF2122/97 LVVQTHRPVETIMASMCSLAQHTTEGWSTKFVGAQIGADAMDTWSRGLER
Rv3529c|M.tuberculosis_H37Rv LVVQTHRPVETIMASMCSLAQHTTEGWSTKFVGAQIGADAMDTWSRGLER
MSMEG_5930|M.smegmatis_MC2_155 LVIQCHRPAETIMASMCSLSAHTTAGWSNTFVGAQIGADAMDTWARGLEA
TH_0375|M.thermoresistible__bu LVVQCHRPAETIMASMCSLSQHTTAGWSNTFVGAQIGADAMETWTRGLRL
MAB_3968|M.abscessus_ATCC_1997 VVVWTHRDPAQTTASSSSMLAHYQALFSDRVDHHELARYWLGKNAQIIDR
* ** * :: : . : :
MMAR_0341|M.marinum_M LVRDRDTIGPERSIDIRFDDFMADEVGVAERIYALAGEPFTDSVRTATAG
MAV_5164|M.avium_104 LVRDRDVIGPDRSIDIRFDDFMADELGVAERVYALADEPFTDDARAAVAD
Mflv_4385|M.gilvum_PYR-GCK CVRDREVIAPDRSLDVRFDDFMADELGVAESIYALTGEDFDGRSRAAVAQ
Mvan_1960|M.vanbaalenii_PYR-1 CVRDRDIIPTERSADITFDAFMADEIGTAERVYRVAGEPLTEESRSAIGR
MUL_4363|M.ulcerans_Agy99 CVRDRDIVPPDRSIDIGFHQLNGNEMALLDELYRCSGVAITPKVRGLFQQ
Mb3559c|M.bovis_AF2122/97 FNAARAKYDSAQFYDVDYHDLIADPLGTVADIYRHFGLTLSDEARQAMTT
Rv3529c|M.tuberculosis_H37Rv FNAARAKYDSAQFYDVDYHDLIADPLGTVADIYRHFGLTLSDEARQAMTT
MSMEG_5930|M.smegmatis_MC2_155 FTAERAKHDPAQFLDVDYDDFVADPLATVESVYRHFGMPYTDAARAAVTE
TH_0375|M.thermoresistible__bu FNEARANYDPAQFHDVEYADFVKDPIGTVEGIYRHFGLEFTDAARDAMTR
MAB_3968|M.abscessus_ATCC_1997 AIAVRAEHP-AAFVDINYTELLDDPIAAVQRIYHAADRRLSDDALTAMRV
* *: : : : :. :* .
MMAR_0341|M.marinum_M YLAGHQRGRLGAVQTSCE-MFGLTEESLRERFAPYL------------KR
MAV_5164|M.avium_104 YLAGHRRGRLGNVETSYE-MFGLDEDSLRERFAPYV------------ER
Mflv_4385|M.gilvum_PYR-GCK YLQSHRRGRHGRVHTSAD-MFGLDPEELRERFAPYS------------AR
Mvan_1960|M.vanbaalenii_PYR-1 YLDGHRRGRHGRVYTSAE-MFGLDPEELRDRFTPYMGWMRNRPARCSQAK
MUL_4363|M.ulcerans_Agy99 YLDGNPRGKHGRVRYHLQRHFGSSAEQLRERFDFYF------------DR
Mb3559c|M.bovis_AF2122/97 VHAESQSGARAPKHSYSLADYGLTVEMVKERFAGL---------------
Rv3529c|M.tuberculosis_H37Rv VHAESQSGARAPKHSYSLADYGLTVEMVKERFAGL---------------
MSMEG_5930|M.smegmatis_MC2_155 VYEASRRGPRAPKHTYSLADYGLTSEAVKERFTGL---------------
TH_0375|M.thermoresistible__bu LHTESQRGPRAPRHSYSLADYGLTAESVRDAFSGL---------------
MAB_3968|M.abscessus_ATCC_1997 SLQQNRQHKHG-EHRYSLAQFGLTIAEVDAAYRRYI------------DH
. :* : :
MMAR_0341|M.marinum_M FLG-----------
MAV_5164|M.avium_104 FLA-----------
Mflv_4385|M.gilvum_PYR-GCK FLS-----------
Mvan_1960|M.vanbaalenii_PYR-1 VTSALG--------
MUL_4363|M.ulcerans_Agy99 FDVRPE--------
Mb3559c|M.bovis_AF2122/97 --------------
Rv3529c|M.tuberculosis_H37Rv --------------
MSMEG_5930|M.smegmatis_MC2_155 --------------
TH_0375|M.thermoresistible__bu --------------
MAB_3968|M.abscessus_ATCC_1997 FAIQTERGGVRGDR