For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TRRPDRKDVATVDELHASATKLVGLDDFGTDDDNYREALGVLLDAYQGEAGLTVLGSKMNRFFLRGALVA RLLSQSAWKQYPEHVDVAIKRPIFVTGLVRTGTTALHRLLGADPAHQGLHMWLAEYPQPRPPRETWESNP LYRQLDAQFTQHHAENPGYTGLHFMAAYELEECWQLLRQSLHSVSYEALAHVPSYADWLSRQDWTPSYCR HRRNLQLIGLNDAEKRWVLKNPSHLFALDALMATYPDALVVQTHRPVETIMASMCSLAQHTTEGWSTKFV GAQIGADAMDTWSRGLERFNAARAKYDSAQFYDVDYHDLIADPLGTVADIYRHFGLTLSDEARQAMTTVH AESQSGARAPKHSYSLADYGLTVEMVKERFAGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3529c | - | - | 100% (384) | hypothetical protein Rv3529c |
| M. tuberculosis H37Rv | Rv2267c | - | 5e-13 | 24.25% (268) | hypothetical protein Rv2267c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3559c | - | 0.0 | 100.00% (384) | hypothetical protein Mb3559c |
| M. gilvum PYR-GCK | Mflv_1531 | - | 1e-169 | 74.34% (378) | hypothetical protein Mflv_1531 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4177c | - | 1e-163 | 71.58% (380) | hypothetical protein MAB_4177c |
| M. marinum M | MMAR_5017 | - | 0.0 | 86.51% (378) | hypothetical protein MMAR_5017 |
| M. avium 104 | MAV_0631 | - | 0.0 | 88.65% (379) | hypothetical protein MAV_0631 |
| M. smegmatis MC2 155 | MSMEG_5930 | - | 1e-172 | 76.00% (375) | hypothetical protein MSMEG_5930 |
| M. thermoresistible (build 8) | TH_0375 | - | 1e-176 | 76.72% (378) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4091 | - | 0.0 | 85.19% (378) | hypothetical protein MUL_4091 |
| M. vanbaalenii PYR-1 | Mvan_5227 | - | 1e-173 | 76.19% (378) | hypothetical protein Mvan_5227 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3529c|M.tuberculosis_H37Rv --MTRRPDRKDVATVDELHASATKLVGLDDFGT-DDDNYREALGVLLDAY
Mb3559c|M.bovis_AF2122/97 --MTRRPDRKDVATVDELHASATKLVGLDDFGT-DDDNYREALGVLLDAY
MMAR_5017|M.marinum_M -----MADRTDVGTVDELHASATKLVGLDDFGS-DQDNYREALEVLLDSY
MUL_4091|M.ulcerans_Agy99 -----MADRTDVGTVDELHASATKLVGLDDFGS-DQDTYREALEVLLDSY
MAV_0631|M.avium_104 -----MSDRTDIGTVEELHASATKLTGLDDFGT-DDDNYLQALEVLLDSY
Mflv_1531|M.gilvum_PYR-GCK -----MSGRTDVGTVEDLHASAVKACGLDDFGS-DDDNYREALAVLLESY
Mvan_5227|M.vanbaalenii_PYR-1 -----MTPRTDVGTVEDLHASAVKACGLDDFGS-DDDNYREALGVLLESY
TH_0375|M.thermoresistible__bu -----MTPRTDVGTVEDLHASAVKACGLEDFGS-DDDNYKEALAVLLDSY
MSMEG_5930|M.smegmatis_MC2_155 -----------MGTVEDLHASATKATGLDDFGT-DDDNYREALGVLLESY
MAB_4177c|M.abscessus_ATCC_199 MSFESSAERTSVGTVDDLHESATRLIGLDDFGDGSVDNYREALGVLLDSY
:.**::** **.: **:*** . *.* :** ***::*
Rv3529c|M.tuberculosis_H37Rv QGEAGLTVLGSKMNRFFLRGALVARLLSQSAWKQYPEHVDVAIKRPIFVT
Mb3559c|M.bovis_AF2122/97 QGEAGLTVLGSKMNRFFLRGALVARLLSQSAWKQYPEHVDVAIKRPIFVT
MMAR_5017|M.marinum_M RREAGLTVLGSKMNRFFLRGALVARLLSEAAWKQYPQYAEVPIQRPIFVT
MUL_4091|M.ulcerans_Agy99 RREAGLTVLGSKMNRFFLRGALVARLLSEAAWKQYPQYAEVPIQRPIFVT
MAV_0631|M.avium_104 RREAGLTVLGSKMNRFFLRGALVARLLSESAWKQYPQYADVAIQRPIFVT
Mflv_1531|M.gilvum_PYR-GCK QRDADLTELGSKMQRFFARNALVARLVSEAAFKQYPEHADVAIERPIFVT
Mvan_5227|M.vanbaalenii_PYR-1 RRDADLTELGSKMQRFFVRNALVARLVSEAAFKQYPEHADVAIERPIFVT
TH_0375|M.thermoresistible__bu QREADLTELGSKMSRFFLRNALVARLVSEAAWKQYPQHADVVIERPIFVT
MSMEG_5930|M.smegmatis_MC2_155 QRDAHLTELGSKMSRFFLRNALVARLLSEASWKANPQYADVEIERPIFVT
MAB_4177c|M.abscessus_ATCC_199 QGEAGLTPLGSKMSRVFLRGALGARLLSEAAFKAHPDYAQVAIDRPIFVT
: :* ** *****.*.* *.** ***:*::::* *::.:* *.******
Rv3529c|M.tuberculosis_H37Rv GLVRTGTTALHRLLGADPAHQGLHMWLAEYPQPRPPRETWESNPLYRQLD
Mb3559c|M.bovis_AF2122/97 GLVRTGTTALHRLLGADPAHQGLHMWLAEYPQPRPPRETWESNPLYRQLD
MMAR_5017|M.marinum_M GLVRTGTTALHRLLGADPAHQGLHMWLAEFPQPRPPRETWETNPFYRQLD
MUL_4091|M.ulcerans_Agy99 GLVRTGTTALHRLLGADPAHQGLHMWLAEFPQPRPPRETWETNPFYRQLD
MAV_0631|M.avium_104 GLVRTGTTALHRLLGADPAHQGLHMWLAEFPQPRPPRETWESNPLYRQLD
Mflv_1531|M.gilvum_PYR-GCK GLPRTGTTAVHRLLAADPRNQGLELWLAEFPQPRPPRETWSQNPVFQQLD
Mvan_5227|M.vanbaalenii_PYR-1 GLPRTGTTAVHRLLAADPRHQGLELWLAEFPQPRPPRETWSQNPVFQALD
TH_0375|M.thermoresistible__bu GLPRTGTTALHRLLAADPAHQGLELWLAEFPQPRPPRETWPDNPIYRQLE
MSMEG_5930|M.smegmatis_MC2_155 GLPRTGTTVLHRLLTADPAHQGLEMWLAEFPQPRPPRETWPDNPVYQQLA
MAB_4177c|M.abscessus_ATCC_199 GLPRTGTTALHRLLNADPMHQGLEMWLADFPQPRPPRDTWDANPVYQQLE
** *****.:**** *** :***.:***::*******:** **.:: *
Rv3529c|M.tuberculosis_H37Rv AQFTQHHAENPGYTGLHFMAAYELEECWQLLRQSLHSVSYEALAHVPSYA
Mb3559c|M.bovis_AF2122/97 AQFTQHHAENPGYTGLHFMAAYELEECWQLLRQSLHSVSYEALAHVPSYA
MMAR_5017|M.marinum_M AQFTQHHKDNPGYTGLHFMAAYELEECWQLLRQSLHSVSYETLAHLPSYA
MUL_4091|M.ulcerans_Agy99 AQLTQHRKDNTGYTGLHFMAAYELEECWQLLRQSLHSVSYETLAHLPSYA
MAV_0631|M.avium_104 AQFTQHHRDNPGYTGLHFMAAYELEECWQLLRQSLHSVSYETLAHVPSYA
Mflv_1531|M.gilvum_PYR-GCK AQFTKAHEENPDYTGLHFMTADEVEECWQLLRQSLHSVSYETLAHVPTYS
Mvan_5227|M.vanbaalenii_PYR-1 AQFTKAHEENPDYTGLHFMTADEVEECWQLLRQSLHSVSYETLAHVPTYS
TH_0375|M.thermoresistible__bu AQFTKAHQENPDYTGLHFMTAGEVEECWQLLRQSVHSVSYETLAHVPSYA
MSMEG_5930|M.smegmatis_MC2_155 ASFSQHHQENPDYTGLHFMTADEVEECWQLLRQSLHSVSYETLAHLPTYA
MAB_4177c|M.abscessus_ATCC_199 GQFSKHHVENPEFMGLHYMSASEVEECWQLLRQSVHSVSYECLAHVPSYA
..::: : :*. : ***:*:* *:**********:****** ***:*:*:
Rv3529c|M.tuberculosis_H37Rv DWLSRQDWTPSYCRHRRNLQLIGLNDAEKRWVLKNPSHLFALDALMATYP
Mb3559c|M.bovis_AF2122/97 DWLSRQDWTPSYCRHRRNLQLIGLNDAEKRWVLKNPSHLFALDALMATYP
MMAR_5017|M.marinum_M QWLAKQDWTPSYQRHRKNLQLIGLNDAEKRWVLKNPSHLFALDALMASYP
MUL_4091|M.ulcerans_Agy99 QWLAKQDWTPSYQRHRKNLQLIGLNDAEKRWVLKNPSHLFALDALMASYP
MAV_0631|M.avium_104 QWLSEQDWTPSYQRHRRNLQLIGLNDADKRWVLKNPSHLFALDALMATYP
Mflv_1531|M.gilvum_PYR-GCK RWLAQQDWAKPYQRHRRNLQLIGLNDREKRWVLKNPSHLFALDALFATYP
Mvan_5227|M.vanbaalenii_PYR-1 QWLARQDWTKSYQRHRRNLQLIGLNDREKRWVLKNPSHLFALDALMATYP
TH_0375|M.thermoresistible__bu RWLARQDWTKPYQRHRRNLQLIGLNDVEKRWVLKNPSHLFALDALFATYP
MSMEG_5930|M.smegmatis_MC2_155 NWLAQQDWTRPYQRHRRNLQLIGLNDAEKRWVLKNPSHLFALDALFATYP
MAB_4177c|M.abscessus_ATCC_199 RWLSGQDWTPAYRRYKANLQLIGLNDIEKRWVLKNPSHLFALDALMEVYP
**: ***: .* *:: ********* :*****************: **
Rv3529c|M.tuberculosis_H37Rv DALVVQTHRPVETIMASMCSLAQHTTEGWSTKFVGAQIGADAMDTWSRGL
Mb3559c|M.bovis_AF2122/97 DALVVQTHRPVETIMASMCSLAQHTTEGWSTKFVGAQIGADAMDTWSRGL
MMAR_5017|M.marinum_M DALVIQTHRPVETIMASMCSLAQHTSEGWSTNFVGAQIGADAMETWSRGL
MUL_4091|M.ulcerans_Agy99 DALVIQTHRPVETIMASMCSLAQHTSEGWSTNFVGAQIGADAMETWSRGL
MAV_0631|M.avium_104 DALVIQTHRPVETIMASMCSLAQHTAEGWSTTFVGAQIGADAMDTWSRGL
Mflv_1531|M.gilvum_PYR-GCK DALVVQCHRPAETIMASMCSLAQHTTEGWSNTFTGEVIGADSMETWSRGL
Mvan_5227|M.vanbaalenii_PYR-1 DALVVQCHRPAETIMASMCSLAQHTTEGWSNTFVGDVIGADSMETWSRGL
TH_0375|M.thermoresistible__bu DALVVQCHRPAETIMASMCSLSQHTTAGWSNTFVGAQIGADAMETWTRGL
MSMEG_5930|M.smegmatis_MC2_155 DALVIQCHRPAETIMASMCSLSAHTTAGWSNTFVGAQIGADAMDTWARGL
MAB_4177c|M.abscessus_ATCC_199 DALVIQTHRPAETIIASVCSLNEHATAGWSETFTGATLGADQLDTWARGL
****:* ***.***:**:*** *:: *** .*.* :*** ::**:***
Rv3529c|M.tuberculosis_H37Rv ERFNAARAKYDSAQFYDVDYHDLIADPLGTVADIYRHFGLTLSDEARQAM
Mb3559c|M.bovis_AF2122/97 ERFNAARAKYDSAQFYDVDYHDLIADPLGTVADIYRHFGLTLSDEARQAM
MMAR_5017|M.marinum_M QRFDSARTNYDPAQFYDVDYRDLIADPMGTVADIYRHFGLTLTDEARAAM
MUL_4091|M.ulcerans_Agy99 QPFDSARTNYDPAQFYDVDYRDLIADPMGTVADIYRHFGLTLTDEARAAM
MAV_0631|M.avium_104 ERFNTARAKYNPAQFYDVDYKELIADPLGTVADIYRHFGLTLTEEAKAAM
Mflv_1531|M.gilvum_PYR-GCK ELFNAERAKHDPAQFYDLDYFALINDPVGAVDDIYRAFGIEFTDAARDAV
Mvan_5227|M.vanbaalenii_PYR-1 ELFNAERAKHDPAQFYDLDYFALIKDPVGAVGDIYRSFGIDFPHAARAAM
TH_0375|M.thermoresistible__bu RLFNEARANYDPAQFHDVEYADFVKDPIGTVEGIYRHFGLEFTDAARDAM
MSMEG_5930|M.smegmatis_MC2_155 EAFTAERAKHDPAQFLDVDYDDFVADPLATVESVYRHFGMPYTDAARAAV
MAB_4177c|M.abscessus_ATCC_199 ESFKSARAKYDESQFCDVDYFDFISDPIGTVESIYRHFGLELSASALVEM
. * *:::: :** *::* :: **:.:* .:** **: . * :
Rv3529c|M.tuberculosis_H37Rv TTVHAESQSGARAPKHSYSLADYGLTVEMVKERFAGL
Mb3559c|M.bovis_AF2122/97 TTVHAESQSGARAPKHSYSLADYGLTVEMVKERFAGL
MMAR_5017|M.marinum_M AKIHAESQTGERAPKHRYSLADYGLTAEAVKERFAGF
MUL_4091|M.ulcerans_Agy99 AKIHAESQTGERAPKHRYSLADYGLTAEAVKERFAGF
MAV_0631|M.avium_104 AKTHADSQSGERAPKHSYSLADYGLSVETVKERFAGL
Mflv_1531|M.gilvum_PYR-GCK VNTHEQSKKGPRAPKHTYSLADYGLTAEQVQERFRGL
Mvan_5227|M.vanbaalenii_PYR-1 TATHEESKKGPRAPKHTYSLSDYGLTDEQVKERFKGL
TH_0375|M.thermoresistible__bu TRLHTESQRGPRAPRHSYSLADYGLTAESVRDAFSGL
MSMEG_5930|M.smegmatis_MC2_155 TEVYEASRRGPRAPKHTYSLADYGLTSEAVKERFTGL
MAB_4177c|M.abscessus_ATCC_199 QKMNDESQKGPRAPKHVYSLADYGLSKEAVMERFAGL
*: * ***:* ***:****: * * : * *: