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MVVPNFPVNRNANGLRSCQARRMNGPRCLIVDDSADFRDAARAMLERGGIVVVGTARDAAEALRRAQELH PDVALVDVDLGAESGFDVAERLDDVPVILTSTHDEQDFADLIAASPALGFLPKLTLSPAAVRKLLDRVSG SPGT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2072 | - | - | 100% (144) | response regulator receiver protein |
| M. vanbaalenii PYR-1 | Mvan_1358 | - | 5e-08 | 32.46% (114) | two component LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2840 | - | 8e-08 | 27.00% (100) | response regulator receiver/ANTAR domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0867c | narL | 6e-08 | 35.29% (119) | nitrate/nitrite response transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0730 | - | 8e-10 | 34.92% (126) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0844c | narL | 5e-08 | 35.29% (119) | nitrate/nitrite response transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02123 | - | 2e-08 | 35.96% (89) | two-component response regulator |
| M. abscessus ATCC 19977 | MAB_0060 | - | 1e-08 | 35.29% (119) | nitrate/nitrite response transcriptional regulatory protein |
| M. marinum M | MMAR_4782 | narL | 2e-08 | 35.29% (119) | nitrate/nitrite response regulator protein NarL |
| M. avium 104 | MAV_4114 | - | 5e-08 | 31.03% (116) | response regulator receiver domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0981 | - | 2e-29 | 57.39% (115) | two-component system regulator |
| M. thermoresistible (build 8) | TH_3563 | - | 2e-08 | 33.33% (117) | PUTATIVE DNA-binding response regulator, LuxR family protein |
| M. ulcerans Agy99 | MUL_0248 | prrA | 2e-08 | 37.50% (88) | two component response transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2072|M.vanbaalenii_PYR-1 MVVPNFPVNRNANGLRSCQARRMNGPRCLIVDDSADFRDAARAMLERGG-
MSMEG_0981|M.smegmatis_MC2_155 -------------------------MRCLIVDDSASFRTAAATMLDSGG-
Mflv_0730|M.gilvum_PYR-GCK -----------------MTG-PGR-VRVVVGDDHPMFRDGVVRALQSSGA
MAB_0060|M.abscessus_ATCC_1997 -----------------MQV-SGELVRVVVGDDHPLFREGVVRALTASGQ
Mb0867c|M.bovis_AF2122/97 -----------------MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGS
Rv0844c|M.tuberculosis_H37Rv -----------------MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGS
MMAR_4782|M.marinum_M -----------------MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGS
MAV_4114|M.avium_104 -----------------MTD-DATPTTVMVVDDHPIWRDAVARDLAESG-
TH_3563|M.thermoresistible__bu -----------------MGE-PQQP-TVMVVDDHPIWREAVARDLAEAG-
MLBr_02123|M.leprae_Br4923 ------------------MDTGVSSPRVLVVDDDSDVLASLERGLRLSG-
MUL_0248|M.ulcerans_Agy99 ---------------MGGMDTGANSPRVLVVDDDSDVLASLERGLRLSG-
:: ** . . * .*
Mvan_2072|M.vanbaalenii_PYR-1 IVVVGTARDAAEALRRAQELHPDVALVDVDLGAESGFDVAER----LDDV
MSMEG_0981|M.smegmatis_MC2_155 VEVVGVASNSAEAMVFCRELQPDVVLVDIALGAESGFELTEKLLGDLEPR
Mflv_0730|M.gilvum_PYR-GCK IDVVAEADDGTAALAAIREHRPAVALLDYRMPGMDGAEVAAAVQ--RGAL
MAB_0060|M.abscessus_ATCC_1997 ITVVAEAENGTGALELIREHRPDVALVDYRMPELDGTQVAAAVR--RDEL
Mb0867c|M.bovis_AF2122/97 VNVVGEADDGAAALELIKAHLPDVALLDYRMPGMDGAQVPAAVR--SYEL
Rv0844c|M.tuberculosis_H37Rv VNVVGEADDGAAALELIKAHLPDVALLDYRMPGMDGAQVAAAVR--SYEL
MMAR_4782|M.marinum_M VNVVGEADDGAAALELIKTHLPDVALLDYRMPRMDGAQVAAAVR--SNEL
MAV_4114|M.avium_104 FAVVATADGVATAQRRAGVVRPDVVVMDMQLPDGDGAQATAAVL--AVSP
TH_3563|M.thermoresistible__bu LSVVATADGVAAARRRAAAVRPDVVLMDMRLPDGDGARATAEVR--AVSP
MLBr_02123|M.leprae_Br4923 -FEVSTAIDGAEALRNATETRPDAIVLDINMPVLDGVSVVTALR--AMDN
MUL_0248|M.ulcerans_Agy99 -FEVSTAVDGAEALRSATETRPDAIVLDINMPVLDGVSVVTALR--AMDN
*. * . : * * . ::* : .*
Mvan_2072|M.vanbaalenii_PYR-1 P--VILTSTHDEQDFADLIAASPALGFLPKLTLSPAAVRKLLDRVSGSPG
MSMEG_0981|M.smegmatis_MC2_155 PPAVILISTYDEQDLSEMIASSPAVGFVPKFALSVPAIQNLLATI-----
Mflv_0730|M.gilvum_PYR-GCK PTRVLLISAHDESAIVYRALADGAAGFLPKESTRNELITAVLDCAKGRDV
MAB_0060|M.abscessus_ATCC_1997 PTRVLLLSAHDDAAIVYRALEEGAAGFLSKESTRTELVGAVLDCARGRDV
Mb0867c|M.bovis_AF2122/97 PTRVLLISAHDEPAIVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDV
Rv0844c|M.tuberculosis_H37Rv PTRVLLISAHDEPAIVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDV
MMAR_4782|M.marinum_M PTRVLLISAHDESAIVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDV
MAV_4114|M.avium_104 SSRVLVLSASDERDDVLQAVKAGAAGYLVKSASKAELAQAVTDTAAGRAV
TH_3563|M.thermoresistible__bu DSRVLVLSASEERDDVLEAVKAGATGYLVKSASKTELVDAVHATAQGRAV
MLBr_02123|M.leprae_Br4923 DVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGA
MUL_0248|M.ulcerans_Agy99 DVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGA
* : *: .. * .:: * :
Mvan_2072|M.vanbaalenii_PYR-1 T-------------------------------------------------
MSMEG_0981|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0730|M.gilvum_PYR-GCK VAPSLAAGLAG---EIRRRAE-----PEGPALSPREREVLVLIAAGSTIP
MAB_0060|M.abscessus_ATCC_1997 VAASLTAGLAG---EIRKRAQ-----PAGPSLSTREREVLRMIAAGQTVP
Mb0867c|M.bovis_AF2122/97 VAPSLVGGLAG---EIRQRAA-----PVAPVLSAREREVLNRIACGQSIP
Rv0844c|M.tuberculosis_H37Rv VAPSLVGGLAG---EIRQRAA-----PVAPVLSAREREVLNRIACGQSIP
MMAR_4782|M.marinum_M VAPSLVGGLAG---EIRQRAA-----PMAPVLSAREREVLHRIAKGQSIP
MAV_4114|M.avium_104 FTPSLAGLVLG---EYRRIAQSKDDGPTRPRLTDRETEVLRYVAKGLSAK
TH_3563|M.thermoresistible__bu FTPGLAGLVLG---EYRRISRQPGAGPDAPRLTERETEILRYVAKGLTAK
MLBr_02123|M.leprae_Br4923 TATSSSETIAVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTTV
MUL_0248|M.ulcerans_Agy99 TATSSSEIITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAV
Mvan_2072|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0981|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0730|M.gilvum_PYR-GCK AMARELFLAPS---------TVKTHVQRLYEKLGVSDRGAAVAEAMRRKL
MAB_0060|M.abscessus_ATCC_1997 AIARALFLAPS---------TVKTHVQRLYEKLGVGDRAAAVAEAMRRGL
Mb0867c|M.bovis_AF2122/97 AIAAELYVAPS---------TVKTHVQRLYEKLGVSDRAAAVAEAMRQRL
Rv0844c|M.tuberculosis_H37Rv AIAAELYVAPS---------TVKTHVQRLYEKLGVSDRAAAVAEAMRQRL
MMAR_4782|M.marinum_M AIAGELYVAPS---------TVKTHVQRLYEKLGVSDRAAAVAEAMRQGL
MAV_4114|M.avium_104 QIAEKLSLSHR---------TVENHVQATFRKLQVANRVELARYAIEHGL
TH_3563|M.thermoresistible__bu QIAAQLSLSHR---------TVENHVQATFRKLQVANRVELARYAIEHGL
MLBr_02123|M.leprae_Br4923 LSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEANSGPRLLHTVRGVGF
MUL_0248|M.ulcerans_Agy99 LSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEANGGPRLLHTVRGVGF
Mvan_2072|M.vanbaalenii_PYR-1 -----
MSMEG_0981|M.smegmatis_MC2_155 -----
Mflv_0730|M.gilvum_PYR-GCK LD---
MAB_0060|M.abscessus_ATCC_1997 LE---
Mb0867c|M.bovis_AF2122/97 LD---
Rv0844c|M.tuberculosis_H37Rv LD---
MMAR_4782|M.marinum_M LD---
MAV_4114|M.avium_104 DEEP-
TH_3563|M.thermoresistible__bu DE---
MLBr_02123|M.leprae_Br4923 VLRMQ
MUL_0248|M.ulcerans_Agy99 VLRMH