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MASLAADCPLDAEVLHTRAREATGLDDFGPDDYRERLEMYLAELREIDMHAPGVVNFHVQLVQWLKNRLL LTDLLTRHPEIEEIELLPPVVIAGLPRSGTTHLHNLLAAAPTFRSLPYWESVEPFPLPAEQGVEPDPRIG RMDLALQTMDLLMPHFALMHEMTTDHAHEEIQLLANDFSTMLMETLAHVPRWTEYYWNRDQTPTYEYLVT QLKALQFLRGGGRWVLKSPQHLAQLPVIGRVLPGVRVVFTHRDPVPVALSMIAMVTYSARMHRDHVDVPV VAAAWVDRLEKLLDACVRDREVIAPDRSLDVRFDDFMADELGVAESIYALTGEDFDGRSRAAVAQYLQSH RRGRHGRVHTSADMFGLDPEELRERFAPYSARFLS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_4385 | - | - | 100% (385) | hypothetical protein Mflv_4385 |
M. gilvum PYR-GCK | Mflv_4115 | - | e-103 | 48.21% (390) | hypothetical protein Mflv_4115 |
M. gilvum PYR-GCK | Mflv_4074 | - | 2e-45 | 33.68% (380) | hypothetical protein Mflv_4074 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3559c | - | 1e-33 | 29.43% (367) | hypothetical protein Mb3559c |
M. tuberculosis H37Rv | Rv3529c | - | 1e-33 | 29.43% (367) | hypothetical protein Rv3529c |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_3968 | - | 1e-51 | 31.51% (384) | putative sulfotransferase |
M. marinum M | MMAR_0341 | - | 1e-155 | 69.09% (385) | hypothetical protein MMAR_0341 |
M. avium 104 | MAV_5164 | - | 1e-160 | 71.24% (386) | hypothetical protein MAV_5164 |
M. smegmatis MC2 155 | MSMEG_5930 | - | 6e-43 | 31.79% (368) | hypothetical protein MSMEG_5930 |
M. thermoresistible (build 8) | TH_0375 | - | 5e-35 | 30.29% (373) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_4363 | - | 4e-70 | 40.94% (381) | hypothetical protein MUL_4363 |
M. vanbaalenii PYR-1 | Mvan_1960 | - | 0.0 | 79.68% (379) | hypothetical protein Mvan_1960 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4385|M.gilvum_PYR-GCK -------------------------------MASLAADCPLDAEVLHTRA Mvan_1960|M.vanbaalenii_PYR-1 --MTDTTDGFIHLDDLAEPRYSPAAQQLREMMATLAADCPLDTDILHARA MMAR_0341|M.marinum_M ------------------------------MMAALAPDCSLDSDALHAKA MAV_5164|M.avium_104 --------MTVRLEDLAEPQFSAEGQQILDMMAAMAPQCPLDADALHAQA MUL_4363|M.ulcerans_Agy99 MEPSSTDIADIDFDDLTRPVLTDVQRQV--LQFTESRHVEFDIAALLAEA Mb3559c|M.bovis_AF2122/97 ------------------------------MTRRPDRKDVATVDELHASA Rv3529c|M.tuberculosis_H37Rv ------------------------------MTRRPDRKDVATVDELHASA MSMEG_5930|M.smegmatis_MC2_155 ---------------------------------------MGTVEDLHASA TH_0375|M.thermoresistible__bu ------------------------------MTPR---TDVGTVEDLHASA MAB_3968|M.abscessus_ATCC_1997 ------------------------------MRAGFKAARPWPIRALNRVG * . Mflv_4385|M.gilvum_PYR-GCK REATGL-DDFGPDD-YR-------------------ERLEMYLAELREID Mvan_1960|M.vanbaalenii_PYR-1 REATGL-DDFGPQD-YR-------------------ERLDRYVAELREID MMAR_0341|M.marinum_M SADTGL-HDFGDDD-YR-------------------ERLDVYLAALAEID MAV_5164|M.avium_104 SADTGL-HDFGPDD-YR-------------------ERLEVYLTALREID MUL_4363|M.ulcerans_Agy99 VDQAGVGDDLGDTDGFG-------------------NRLRAHVAAIEGDQ Mb3559c|M.bovis_AF2122/97 TKLVGLDDFGTDDDNYR-------------------EALGVLLDAYQGEA Rv3529c|M.tuberculosis_H37Rv TKLVGLDDFGTDDDNYR-------------------EALGVLLDAYQGEA MSMEG_5930|M.smegmatis_MC2_155 TKATGLDDFGTDDDNYR-------------------EALGVLLESYQRDA TH_0375|M.thermoresistible__bu VKACGLEDFGSDDDNYK-------------------EALAVLLDSYQREA MAB_3968|M.abscessus_ATCC_1997 NPLTGIGAAPTLDTQWLRSAARRATGLEWVADAYLDDALEVLAASLRNDA *: : : * Mflv_4385|M.gilvum_PYR-GCK -MHAPGVVNFHVQLVQWLKNRLLLTDLLTRHPEIEEIELLPPVVIAGLPR Mvan_1960|M.vanbaalenii_PYR-1 -MHGPGIVNFHAQLVQWLKNRLLLTDLLARHPEIEDIELVAPVVIAGLPR MMAR_0341|M.marinum_M GMQPAGVVNFYGQLLQLLKNRLLLSELRHRHPEIDDIELQPPVVIAGLPR MAV_5164|M.avium_104 GLHAAGTVNFYGQLLQILKNRLLLTDLLKRHPEIHDIELRSPVVIAGLPR MUL_4363|M.ulcerans_Agy99 GLTQLTRSSLRQRVVRLLRNRLSLTDLIRRYPEIESIRIEKPFVVVGMPR Mb3559c|M.bovis_AF2122/97 GLTVLGSKMNRFFLRGALVARLLSQSAWKQYPEHVDVAIKRPIFVTGLVR Rv3529c|M.tuberculosis_H37Rv GLTVLGSKMNRFFLRGALVARLLSQSAWKQYPEHVDVAIKRPIFVTGLVR MSMEG_5930|M.smegmatis_MC2_155 HLTELGSKMSRFFLRNALVARLLSEASWKANPQYADVEIERPIFVTGLPR TH_0375|M.thermoresistible__bu DLTELGSKMSRFFLRNALVARLVSEAAWKQYPQHADVVIERPIFVTGLPR MAB_3968|M.abscessus_ATCC_1997 KLSFLGRKMVQVRLVGMLSTRLRLRELIRKNPGIAQLPVEPPIVIVGLQR : : * ** * .: : *..:.*: * Mflv_4385|M.gilvum_PYR-GCK SGTTHLHNLLAAAPTFRSLPYWESVEPFPLPAEQG--VEPDPRIGRMDLA Mvan_1960|M.vanbaalenii_PYR-1 SGTTHLHNMLASAPTFRSLPYWESVEPFPLPAEAG--IEPDPRVGRMDVA MMAR_0341|M.marinum_M TGTTHLHNMLAAPTTFRTMPYWESVEPFPLPQEAG--VEPDPRLVRMDVA MAV_5164|M.avium_104 TGTTHLHNLLAAPPTFRTMPYWESVEPFPMPNEVG--VQPDPRRTRMDVA MUL_4363|M.ulcerans_Agy99 SGTTHLVNLLAADPRRRALPYWESQDPIPARGQGPDIFGVDPRYTRAKTE Mb3559c|M.bovis_AF2122/97 TGTTALHRLLGADPAHQGLHMWLAEYPQPRPPRET--WESNPLYRQLDAQ Rv3529c|M.tuberculosis_H37Rv TGTTALHRLLGADPAHQGLHMWLAEYPQPRPPRET--WESNPLYRQLDAQ MSMEG_5930|M.smegmatis_MC2_155 TGTTVLHRLLTADPAHQGLEMWLAEFPQPRPPRET--WPDNPVYQQLAAS TH_0375|M.thermoresistible__bu TGTTALHRLLAADPAHQGLELWLAEFPQPRPPRET--WPDNPIYRQLEAQ MAB_3968|M.abscessus_ATCC_1997 TGTTLLHRLLAADPSAGSMSSWEGASPLPHPEQPS--GAPDLRIAQAAKD :*** * .:* : . : * . * * . : : Mflv_4385|M.gilvum_PYR-GCK LQTMDLLMPHFALMHEMTTDHAHEEIQLLANDFSTMLMETLAHVPRWTEY Mvan_1960|M.vanbaalenii_PYR-1 VQTMDLLMPHFALMHEMTTDHVHEEIQLLANDFSTMLMDTLAHVPRWTDY MMAR_0341|M.marinum_M VGVINTVMPHFALMHEMTADHVHEEIQLLANDFSTMLFETLGHVPRWRDY MAV_5164|M.avium_104 VAVINTVMPHFALMHEMTTDHVHEEIQLLANDVSTMLLETLAEVPRWRAY MUL_4363|M.ulcerans_Agy99 HDALMATAPVVAAMHDRFPEAIEEEVELLDLDLASYVLEWHARVPDWRDY Mb3559c|M.bovis_AF2122/97 FTQHHAENPGYTGLHFMAAYELEECWQLLRQSLHSVSYEALAHVPSYADW Rv3529c|M.tuberculosis_H37Rv FTQHHAENPGYTGLHFMAAYELEECWQLLRQSLHSVSYEALAHVPSYADW MSMEG_5930|M.smegmatis_MC2_155 FSQHHQENPDYTGLHFMTADEVEECWQLLRQSLHSVSYETLAHLPTYANW TH_0375|M.thermoresistible__bu FTKAHQENPDYTGLHFMTAGEVEECWQLLRQSVHSVSYETLAHVPSYARW MAB_3968|M.abscessus_ATCC_1997 ERSLRYLAPQFFAIHSVEAEAPEEDVLLLDFALHSQMPEVMFHVPGYAKW * :* . .* ** . : : .:* : : Mflv_4385|M.gilvum_PYR-GCK YWNRDQTPTYEYLVTQLKALQFLRGGGRWVLKSPQHLAQLPVIGRVLPGV Mvan_1960|M.vanbaalenii_PYR-1 FWSTDQTSSYRYLVTQLKALQFLRGGRRWILKSPQHLGQLPVLDEVMPGV MMAR_0341|M.marinum_M YETHDQTPHYQYLATQLKAMQFLRGGRRWLLKSPQHLEQVPVLDRVFPGS MAV_5164|M.avium_104 YQAHDQTPHYEYLATQLRAMQFLRGGRRWLLKSPQHLEQVPVLDRVFPDS MUL_4363|M.ulcerans_Agy99 YLGLDQRRHYAYLKKVLQALTFLRGPQTWVLKRPQHCEQLGPLMATFPDA Mb3559c|M.bovis_AF2122/97 LSRQDWTPSYCRHRRNLQLIGLNDAEKRWVLKNPSHLFALDALMATYPDA Rv3529c|M.tuberculosis_H37Rv LSRQDWTPSYCRHRRNLQLIGLNDAEKRWVLKNPSHLFALDALMATYPDA MSMEG_5930|M.smegmatis_MC2_155 LAQQDWTRPYQRHRRNLQLIGLNDAEKRWVLKNPSHLFALDALFATYPDA TH_0375|M.thermoresistible__bu LARQDWTKPYQRHRRNLQLIGLNDVEKRWVLKNPSHLFALDALFATYPDA MAB_3968|M.abscessus_ATCC_1997 LADQDMTPAYELHRLLLQVLQWQQPRGRWVLKTPAHLEHLDVLLRVYPGA * * *: : *:** * * : : . *. Mflv_4385|M.gilvum_PYR-GCK RVVFTHRDPVPVALSMIAMVTYSARMHRDHVDVPVVAAAWVDRLEKLLDA Mvan_1960|M.vanbaalenii_PYR-1 VVVFTHRDPVPVALSMIAMVTYSERMHRDKVDVPTVARAWVDRLEHLLNA MMAR_0341|M.marinum_M IVLFTHRDPVPVALSMLAMITYSARMHRWPVPVEQIAHYWVDRLDRMLAT MAV_5164|M.avium_104 IVVFTHRDPVPVALSMIAMITYSARMHRSPVPVRQIAESWIDRLGQMLAA MUL_4363|M.ulcerans_Agy99 TVAFTHRDPVAVIQSTITMMAYSDRLRRTSIDAGWLLDYWSDRVYPLLWA Mb3559c|M.bovis_AF2122/97 LVVQTHRPVETIMASMCSLAQHTTEGWSTKFVGAQIGADAMDTWSRGLER Rv3529c|M.tuberculosis_H37Rv LVVQTHRPVETIMASMCSLAQHTTEGWSTKFVGAQIGADAMDTWSRGLER MSMEG_5930|M.smegmatis_MC2_155 LVIQCHRPAETIMASMCSLSAHTTAGWSNTFVGAQIGADAMDTWARGLEA TH_0375|M.thermoresistible__bu LVVQCHRPAETIMASMCSLSQHTTAGWSNTFVGAQIGADAMETWTRGLRL MAB_3968|M.abscessus_ATCC_1997 VVVWTHRDPAQTTASSSSMLAHYQALFSDRVDHHELARYWLGKNAQIIDR * ** * :: : . : : Mflv_4385|M.gilvum_PYR-GCK CVRDREVIAPDRSLDVRFDDFMADELGVAESIYALTGEDFDGRSRAAVAQ Mvan_1960|M.vanbaalenii_PYR-1 CVRDRDIIPTERSADITFDAFMADEIGTAERVYRVAGEPLTEESRSAIGR MMAR_0341|M.marinum_M LVRDRDTIGPERSIDIRFDDFMADEVGVAERIYALAGEPFTDSVRTATAG MAV_5164|M.avium_104 LVRDRDVIGPDRSIDIRFDDFMADELGVAERVYALADEPFTDDARAAVAD MUL_4363|M.ulcerans_Agy99 CVRDRDIVPPDRSIDIGFHQLNGNEMALLDELYRCSGVAITPKVRGLFQQ Mb3559c|M.bovis_AF2122/97 FNAARAKYDSAQFYDVDYHDLIADPLGTVADIYRHFGLTLSDEARQAMTT Rv3529c|M.tuberculosis_H37Rv FNAARAKYDSAQFYDVDYHDLIADPLGTVADIYRHFGLTLSDEARQAMTT MSMEG_5930|M.smegmatis_MC2_155 FTAERAKHDPAQFLDVDYDDFVADPLATVESVYRHFGMPYTDAARAAVTE TH_0375|M.thermoresistible__bu FNEARANYDPAQFHDVEYADFVKDPIGTVEGIYRHFGLEFTDAARDAMTR MAB_3968|M.abscessus_ATCC_1997 AIAVRAEHP-AAFVDINYTELLDDPIAAVQRIYHAADRRLSDDALTAMRV * *: : : : :. :* . Mflv_4385|M.gilvum_PYR-GCK YLQSHRRGRHGRVHTSAD-MFGLDPEELRERFAPYS------------AR Mvan_1960|M.vanbaalenii_PYR-1 YLDGHRRGRHGRVYTSAE-MFGLDPEELRDRFTPYMGWMRNRPARCSQAK MMAR_0341|M.marinum_M YLAGHQRGRLGAVQTSCE-MFGLTEESLRERFAPYL------------KR MAV_5164|M.avium_104 YLAGHRRGRLGNVETSYE-MFGLDEDSLRERFAPYV------------ER MUL_4363|M.ulcerans_Agy99 YLDGNPRGKHGRVRYHLQRHFGSSAEQLRERFDFYF------------DR Mb3559c|M.bovis_AF2122/97 VHAESQSGARAPKHSYSLADYGLTVEMVKERFAGL--------------- Rv3529c|M.tuberculosis_H37Rv VHAESQSGARAPKHSYSLADYGLTVEMVKERFAGL--------------- MSMEG_5930|M.smegmatis_MC2_155 VYEASRRGPRAPKHTYSLADYGLTSEAVKERFTGL--------------- TH_0375|M.thermoresistible__bu LHTESQRGPRAPRHSYSLADYGLTAESVRDAFSGL--------------- MAB_3968|M.abscessus_ATCC_1997 SLQQNRQHKHG-EHRYSLAQFGLTIAEVDAAYRRYI------------DH . :* : : Mflv_4385|M.gilvum_PYR-GCK FLS----------- Mvan_1960|M.vanbaalenii_PYR-1 VTSALG-------- MMAR_0341|M.marinum_M FLG----------- MAV_5164|M.avium_104 FLA----------- MUL_4363|M.ulcerans_Agy99 FDVRPE-------- Mb3559c|M.bovis_AF2122/97 -------------- Rv3529c|M.tuberculosis_H37Rv -------------- MSMEG_5930|M.smegmatis_MC2_155 -------------- TH_0375|M.thermoresistible__bu -------------- MAB_3968|M.abscessus_ATCC_1997 FAIQTERGGVRGDR