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MGDRYRVWLGAGVLAGGVSAAMLAGAGVAAADDGTSSGSGSQAASGSDDADGRDSKAGPAAESGTDQQAG DEPDAETPADEAEPEPEPDEDPEDEDPEDEDPEDEDLEDEDPEPDADADADRNDRDTTDEAPAPPSGGKH AAPEPEDAPAEPEPEPPAETPAVVNEPETGPVDAEPEAPSTLVDTVETDLSAPDGAAVMKLAAASSPWPG SGVTSLFDFVENLAASFYDWYTDTMQFLAGPARAPFGSRVRVERSSLTVGEGVVVSADWYFPPGNTPPKG LIYLQHGMLASASFYSATAAYLAEKTHSIVVAPTLTWNVLDTENYPLLLPSTHRAVAELFTGDRAELTAS AREAGFTGELPTRVVLAGHSAGGGLVVGTARYMVENGDGDDLAGVVMLDGAGIIGVLSADLAKIPQSIPV YNLAATPDSWNNNGHASQRLKQARPDMFTGVLVQGGHHSDSMQSASGIVQFMAYMATGFSSPWNVEANEI LTAGWINDMLDGTHTERLYRTSVSPFGLVTGAWIDPPSSVRVGALTAATAGAGDVCPVTPTAVTCADPLP QSGAARGRAALV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_1255 | - | - | 100% (572) | hypothetical protein Mvan_1255 |
M. vanbaalenii PYR-1 | Mvan_1256 | - | 2e-83 | 39.07% (517) | hypothetical protein Mvan_1256 |
M. vanbaalenii PYR-1 | Mvan_0370 | - | 5e-68 | 36.36% (528) | hypothetical protein Mvan_0370 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3469c | - | 3e-10 | 29.67% (209) | hypothetical protein Mb3469c |
M. gilvum PYR-GCK | Mflv_5098 | - | 3e-74 | 37.10% (531) | hypothetical protein Mflv_5098 |
M. tuberculosis H37Rv | Rv3439c | - | 3e-10 | 29.67% (209) | hypothetical protein Rv3439c |
M. leprae Br4923 | MLBr_01468 | - | 4e-06 | 32.00% (100) | putative ribonuclease |
M. abscessus ATCC 19977 | MAB_0869c | - | 2e-09 | 31.58% (171) | resuscitation-promoting factor RpfA |
M. marinum M | MMAR_3402 | - | 6e-37 | 38.68% (243) | PE-PGRS family protein |
M. avium 104 | MAV_3172 | - | 1e-11 | 35.38% (130) | prolipoprotein diacylglyceryl transferase |
M. smegmatis MC2 155 | MSMEG_3222 | - | 3e-09 | 29.58% (240) | prolipoprotein diacylglyceryl transferase |
M. thermoresistible (build 8) | TH_3241 | - | 7e-09 | 26.32% (171) | PUTATIVE putative FHA domain containing protein |
M. ulcerans Agy99 | MUL_3715 | rne | 6e-11 | 28.87% (142) | ribonuclease E Rne |
CLUSTAL 2.0.9 multiple sequence alignment MAV_3172|M.avium_104 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 -------------------------------------------------- Mb3469c|M.bovis_AF2122/97 -------------------------------------------------- Rv3439c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01468|M.leprae_Br4923 MIDGAPPLEPSKEPTQHMELPDRLRVHSLARTLGTTSRRVLDVLSALDGR MUL_3715|M.ulcerans_Agy99 MVDGAPSSDPENEPTQREDLPDRLRVHSLARTLGTSSRRVLDALSALDGR MAB_0869c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3241|M.thermoresistible__bu -------------------------------------------------- Mvan_1255|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_5098|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3402|M.marinum_M -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 -------------------------------------------------- Mb3469c|M.bovis_AF2122/97 -------------------------------------------------- Rv3439c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01468|M.leprae_Br4923 IRSAHSSVDRVDAVRVRDLLASQPNSPHELT-----------AVPDNP-- MUL_3715|M.ulcerans_Agy99 IRSAHSSVDRVDAVRVRDLLAEQPAEEGQAEEDQQAPDAVAAEVPDAPGE MAB_0869c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3241|M.thermoresistible__bu -------------------------------------------------- Mvan_1255|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_5098|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3402|M.marinum_M -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 -------------------------------------------------- Mb3469c|M.bovis_AF2122/97 -------------------------------------------------- Rv3439c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01468|M.leprae_Br4923 -------VALEERDSRLVLETTVERPHYMPLFVAPQPIEVDDDSCADDDV MUL_3715|M.ulcerans_Agy99 PAEPESRLMLETQETVQVVETWVERPHYMPLFVAPQPISEP-VAGDDADD MAB_0869c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3241|M.thermoresistible__bu -------------------------------VGAPPRSKEVMVNVTLGVF Mvan_1255|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_5098|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3402|M.marinum_M -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 -------------------------------------------------- Mb3469c|M.bovis_AF2122/97 -------------------------------------------------- Rv3439c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01468|M.leprae_Br4923 ESGDDSDVGDDEEQPDRPANRRRRRGRRGRGRGRGEQGGSDVQS---DDV MUL_3715|M.ulcerans_Agy99 ESGDEGD--DDEEQADRPGNRRRRRGRRGRGRGRGEQGANDGQDQPGDDG MAB_0869c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3241|M.thermoresistible__bu VESGTARIVLVDADPPNPVVDQTDLDLAAADSTPDTLVTTVLATAGALTE Mvan_1255|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_5098|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3402|M.marinum_M -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 -------------------------------------------------- Mb3469c|M.bovis_AF2122/97 -------------------------------------------------- Rv3439c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01468|M.leprae_Br4923 DGA-----VDSTESEDFDGQDFDESEDTEIGYDESGSSEAGNRRRRRRRR MUL_3715|M.ulcerans_Agy99 DEAPQKAGGNSTSSDDSEAQDGADSEESDNGDDDNGSADGASRRRRRRRR MAB_0869c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3241|M.thermoresistible__bu SGHRLVGISLCGPAADRIGPVHDALTGSGLRPVTVVDESDAVTAVVRTLA Mvan_1255|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_5098|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3402|M.marinum_M -------------------------------------------------- MAV_3172|M.avium_104 -------------------------------------------------- MSMEG_3222|M.smegmatis_MC2_155 -------------------------------------------------- Mb3469c|M.bovis_AF2122/97 -------------------------------------------------- Rv3439c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01468|M.leprae_Br4923 RKSGVGED--EGCAPDDPPNTVVHERTPRAAGRSASFDNGVNGTGSADIK MUL_3715|M.ulcerans_Agy99 RKSGAGDDGDEGPAPDDPPNTVVHERAPRSGDKSGNSDSGDD-SGGNEIK MAB_0869c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3241|M.thermoresistible__bu GDETVATLVNDGATVALSMTEAGGVTTPVATEPIDGDPQAAYRTLVERFA Mvan_1255|M.vanbaalenii_PYR-1 ----------------MGDRYRVWLGAGVLAGGVSAAMLAGAGVAAADDG Mflv_5098|M.gilvum_PYR-GCK ----------------MVDRLSVLIGAGVLTAGMSAAVLTGAGVAIASPD MMAR_3402|M.marinum_M ------------------------------------------------MS MAV_3172|M.avium_104 ----MTKLLAYFPSPPQGV-------------WHLGPVPIRAYALFIIAG MSMEG_3222|M.smegmatis_MC2_155 ---MTTTVLAYLPSPSQGV-------------WHLGPVPIRAYALCIIVG Mb3469c|M.bovis_AF2122/97 ----MADRLNVAERLAEGR-------------PAAEHTQSYVRACHLVGY Rv3439c|M.tuberculosis_H37Rv ----MADRLNVAERLAEGR-------------PAAEHTQSYVRACHLVGY MLBr_01468|M.leprae_Br4923 GIDGSTRLEAKRQRRRDGRDAGRRRSSVLSEAEFLARRESVERVMVVRDR MUL_3715|M.ulcerans_Agy99 GIDGSTRLEAKRQRRRDGRDAGRRRPPVLSEAEFLARREAVERVMVVRDR MAB_0869c|M.abscessus_ATCC_199 -----------------------------------------------MSG TH_3241|M.thermoresistible__bu ADPGAASGLIVMGSLGDGG-----------LPADLVETSPVPLRFPDDPE Mvan_1255|M.vanbaalenii_PYR-1 TSSGSGSQAASGSDDADGR--------------DSKAGPAAESGTDQQAG Mflv_5098|M.gilvum_PYR-GCK TASSTSETSETSDTSGSER----------------VSEKPADPRGEKADE MMAR_3402|M.marinum_M TYVIAAPDAFSVASGELAG----------------IEAAVKGAAAAAAPS MAV_3172|M.avium_104 IVAALLIGDRRWEARGGERG--VIYDIALWTVPFGLVGGRLYHLAT---- MSMEG_3222|M.smegmatis_MC2_155 IVAALVIGDRRWQARGGEPG--VIYDIALWAVPFGLAGGRIYHVIT---- Mb3469c|M.bovis_AF2122/97 QHPDLTAYPAQIHDWYGSEDGLDLHALDADCAQLRAAASVLMEALR---- Rv3439c|M.tuberculosis_H37Rv QHPDLTAYPAQIHDWYGSEDGLDLHALDADCAQLRAAASVLMEALR---- MLBr_01468|M.leprae_Br4923 IRTEPPHPGARYTQIAVLEDGIVVEHFVTSAASASLVGNIYLGIVQNVLP MUL_3715|M.ulcerans_Agy99 VRTEPPHPGSRYTQIAVLEDGIVVEHFVTSAASASLVGNIYLGIVQNVLP MAB_0869c|M.abscessus_ATCC_199 RHSKPSKASAKAAKVAVAGAGLVGGGLMMAATANAATDGEWDQVAR---- TH_3241|M.thermoresistible__bu FMLARGATLASLSQDATMAAPVVADELPTTVTPLETADTMQSQQLAYSEV Mvan_1255|M.vanbaalenii_PYR-1 DEPDAETPADEAEPEPEPDEDPEDEDPEDEDPEDEDLEDEDPEPDADADA Mflv_5098|M.gilvum_PYR-GCK TPDETEAPDSVEDVVQDLDDEPDETDDRDDAATEADLDTDVAVDAD---- MMAR_3402|M.marinum_M TTGIISAAADEVSTAIARLFGSYADEFQTLSAQATRFQAQFERALS---- MAV_3172|M.avium_104 -----------DWRTYWGP-----GGAGFGAAVRIWDGGLGIWGAVALGA MSMEG_3222|M.smegmatis_MC2_155 -----------DWKTYFGP-----TGKGFGAALQIWEGGLGIWGAVAFGA Mb3469c|M.bovis_AF2122/97 -----------MERSQVAVLAAAWTGSGADAAVHFVQRHCETGNSVVTEV Rv3439c|M.tuberculosis_H37Rv -----------MERSQVAVLAAAWTGSGADAAVHFVQRHCETGNSVVTEV MLBr_01468|M.leprae_Br4923 SMEAAFVDIGRGRNGVLYAGEVNWEAAGLGGADRKIEQALKPGDYIVVQV MUL_3715|M.ulcerans_Agy99 SMEAAFVDIGRGRNGVLYAGEVNWDAAGLGGADRKIEQALKPGDYIVVQV MAB_0869c|M.abscessus_ATCC_199 ---------------------------CESGGNWAINTGNGYQGGLQFSP TH_3241|M.thermoresistible__bu P---------DEDSDLLGFTDPVDTPGADGPAGGFDPEAEDAEDADAEDA Mvan_1255|M.vanbaalenii_PYR-1 D-----------RNDRDTTDEAPAPPSGGKHAAPEPEDAPAEPEPEPPAE Mflv_5098|M.gilvum_PYR-GCK -----------------------------EADEVADVEEPQADVEVPAVE MMAR_3402|M.marinum_M ---------------------------EAGAAYAAAEAANVSPLRALLQE MAV_3172|M.avium_104 VGAWIGCRRHGIP-LPAFADALAPGIILAQAIGRLGN----YFNQELYGR MSMEG_3222|M.smegmatis_MC2_155 VGAWIACRLRGIP-LPAFGDAIAPGIILAQGIGRLGN----YFNQELYGR Mb3469c|M.bovis_AF2122/97 RAAAQRCESLRDN-LWQLVDSKVATAIAIDERALAQRPAWLAAAEALTTE Rv3439c|M.tuberculosis_H37Rv RAAAQRCESLRDN-LWQLVDSKVATAIAIDERALAQRPAWLAAAEALTTE MLBr_01468|M.leprae_Br4923 NKDPVGHKGARLTTQVSLAGRYLVYVPGASSTGISRKLPDTERQRLKEIL MUL_3715|M.ulcerans_Agy99 SKDPVGHKGARLTTQVSLAGRYLVYVAGASSTGISRKLPDTERQRLKEIL MAB_0869c|M.abscessus_ATCC_199 -STWINSGGGQYAPSAHLATKEQQIAVAEKVLAGQGRGAWPVCGRGLSGS TH_3241|M.thermoresistible__bu VRRRQWLIGSSVGALAAVGFATLAVSVAITIEPTSSQQAVRLQEGPVPGK Mvan_1255|M.vanbaalenii_PYR-1 TPAVVNEPETGPVDAEPEAPSTLVDTVETDLSAPDGAAVMKLAAASSPWP Mflv_5098|M.gilvum_PYR-GCK VPAVVDQPASTVAVEEPVAAVLVPATTTTPIEA--------HVARASASE MMAR_3402|M.marinum_M AESLGVFAPIERLIGRPLFGNGSVAAASTGATEASSLLTSGTNQAGLGGA MAV_3172|M.avium_104 ETTLPWGLEIFYRRDPSGYIDPHSLDGVSTGQVALVVQPTFLYE--LLWN MSMEG_3222|M.smegmatis_MC2_155 PTDVPWGLEIYERLNKFGQSD--QLNGVSTGQVTAVVHPTFLYE--LIWN Mb3469c|M.bovis_AF2122/97 GADRPTAVEVVRQQIQP-YVDDDVRNDWLTTMRSTTAGVAASYD--AVTD Rv3439c|M.tuberculosis_H37Rv GADRPTAVEVVRQQIQP-YVDDDVRNDWLTTMRSTTAGVAASYD--AVTD MLBr_01468|M.leprae_Br4923 REVVPPDAGVIIRTASEGVKEEDIRKDVTRLQEHWEQIEAKTIQ--TKEK MUL_3715|M.ulcerans_Agy99 REVVPSDAGVIIRTASEGVKEDDIRADVTRLQERWNQIEAKAVE--IKQK MAB_0869c|M.abscessus_ATCC_199 TPRTAPAANITP--------AAHHEEQAAAEPAPAPEPPAEGDE--QFVA TH_3241|M.thermoresistible__bu AFPVAPGQGVEPDGPNWTMIEHLPPPGAPAEVRTFETRALSSSR--DVSK Mvan_1255|M.vanbaalenii_PYR-1 GSGVTSLFDFVENLAASFYDWYTDTMQFLAGPARAPFGSRVRVE--RSSL Mflv_5098|M.gilvum_PYR-GCK AATPPRRQTLLSVLGAVVFNIYSVALRVLGGPPILPPNSTVTVRSSTLTI MMAR_3402|M.marinum_M VNYAAAEALAAPATGATGVKSGFSFLQIPIGPSEFLGITIPQFN------ . MAV_3172|M.avium_104 LLIFVALLYADRRLTLGHGR-LFALYVAGYCVGRFCVELLRDDTATHIAG MSMEG_3222|M.smegmatis_MC2_155 IAVFGFLIWVDRKFRIGHGR-LFALYVASYCVGRFWVELMRSDTATEFAG Mb3469c|M.bovis_AF2122/97 QLASAPRAHFEIPDDLGPGRQPSPASVPAQPSATAAITPAAALPPPDPVP Rv3439c|M.tuberculosis_H37Rv QLASAPRAHFEIPDDLGPGRQPSPASVPAQPSATAAITPAAALPPPDPVP MLBr_01468|M.leprae_Br4923 AAGAAVALYEEPDVLVKVIRDLFNDDFSGLVVSGDEAWNTINEYVNSVAP MUL_3715|M.ulcerans_Agy99 AAGAAVALYEEPDVLVKVIRDLFNEDFAGLVVSGDDAWDTINEYVSSVAP MAB_0869c|M.abscessus_ATCC_199 EAPEAPAIDEAPAPEEAPAPEAQDVDFQSGPAPEEPAPAPEPAPVDEAQA TH_3241|M.thermoresistible__bu AAAPAIVNVYRDGTVAVQNAAAPLLPVGPAPALPGTVPVTVPGPVFAEWP Mvan_1255|M.vanbaalenii_PYR-1 TVGEGVVVSADWYFPPGNTPPKGLIYLQHGMLASASFYSATAAYLAEKTH Mflv_5098|M.gilvum_PYR-GCK DCGDGYEVPADWYVPDGPTP-TRLIYFQHGFMAAGPFYSFTAARLAEATH MMAR_3402|M.marinum_M --FPAPAHWYFPTQADGSVNANGVIYLQHGFGAIGWFYQPLAMQLAQQTN . MAV_3172|M.avium_104 IRINSFTSTFVFIG----------AVVYLMAAPKGREDPESLRGNQYVEE MSMEG_3222|M.smegmatis_MC2_155 IRVNTFTSTFVFIG----------AVVYIMLAPKGREEPESLRGKAADET Mb3469c|M.bovis_AF2122/97 AVTSRPVTPSDFGS----------APGDGSATPAGVGSAGGFGDAGGTGG Rv3439c|M.tuberculosis_H37Rv AVTSRPVTPSDFGS----------APGDGSATPAGVGSAGGFGDAGGTGG MLBr_01468|M.leprae_Br4923 ELVSKLTKYDPPIGPDGQHGPDVFAVHRIDEQLAKAMDRKVWLPSGGTLV MUL_3715|M.ulcerans_Agy99 DLVSKLSKYEPAVGSEGQVGPDVFAVHRIDEHLAKAMDRKVWLPSGGTLV MAB_0869c|M.abscessus_ATCC_199 PAPELIAAPAPEAP-----------VVDEAPAPEEAPAPEAPAADDQVLP TH_3241|M.thermoresistible__bu EYVTRLIPDFSRIRPVDLLYFLANLRELLPPLEATTPDPDDGFDIGDIGV Mvan_1255|M.vanbaalenii_PYR-1 SIVVAPTLTWNVLDT---------ENYPLLLPSTHRAVAELFTGDRAELT Mflv_5098|M.gilvum_PYR-GCK SIVVTTSLTSNFLAC---------DGCWVGGTPMHRAVADLFGDGNSALG MMAR_3402|M.marinum_M SIVVVPTVPSIPLP----------FGMWIGGAQMQQGVGSLFLGSQTALN MAV_3172|M.avium_104 EPAEPE----------------PATVAATTEAATEG----------VAAP MSMEG_3222|M.smegmatis_MC2_155 EEGDEESLVDEAGKELVAAAAGTGVVAAATAAAREDTDDTDGTTDPAAAS Mb3469c|M.bovis_AF2122/97 LGGFAG------------LAGLANRIVDAVDS------------------ Rv3439c|M.tuberculosis_H37Rv LGGFAG------------LAGLANRIVDAVDS------------------ MLBr_01468|M.leprae_Br4923 IDRTEAMTVIDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQLRLRDIGG MUL_3715|M.ulcerans_Agy99 IDRTEAMTVVDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQLRLRDIGG MAB_0869c|M.abscessus_ATCC_199 YELQSG-------------------------------------------- TH_3241|M.thermoresistible__bu LAVVPR----DQGVLFSADADAAGPEMIPARLFDPQTPAADKTQLLPPGT Mvan_1255|M.vanbaalenii_PYR-1 ASAREAG----------FTGELPTRVVLAGHSAGGGLVVGTARYMVENGD Mflv_5098|M.gilvum_PYR-GCK DSAVAAG-------YAGALLDGVDKVALIGHSAGGGLAAGAAAAMTGTGA MMAR_3402|M.marinum_M ISANQAG----------YLGTLPQDFILSGHSAGGGLASIAAGSYLANLG MAV_3172|M.avium_104 -------------------ADGAEAAGAD--------------------- MSMEG_3222|M.smegmatis_MC2_155 DEPGDEAEPETEAATAVLTADGAEAMSVDEQPDDDEAVDEEAGQEAEEPA Mb3469c|M.bovis_AF2122/97 -----------------LLGSVAEQLGDP--------------------- Rv3439c|M.tuberculosis_H37Rv -----------------LLGSVAEQLGDP--------------------- MLBr_01468|M.leprae_Br4923 IVVIDFIDMVLESNRDLVLRRLTEVLARDRTRHQVSEVTSLG-------- MUL_3715|M.ulcerans_Agy99 IVVIDFIDMVLESNRDLVLRRLTEALARDRTRHQVSEVTSLG-------- MAB_0869c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3241|M.thermoresistible__bu TVLDVPTDGDGDDPTAALTGEPTTGDTDE--------------------- Mvan_1255|M.vanbaalenii_PYR-1 GDDLAGVVMLDGAGIIGVLSADLAKIPQS--------------------- Mflv_5098|M.gilvum_PYR-GCK FDRLAGVVMLDGVGFGDVTPRALERLPLD--------------------- MMAR_3402|M.marinum_M AATNHLQGVVMFDGVASNSSAFGAAVANLQAAN----------------- MAV_3172|M.avium_104 ------------------ATAQRPEESAEPDVE----------------- MSMEG_3222|M.smegmatis_MC2_155 DELVELADEPEGEPEPAAAEEAEPAETIEPDEDEIFDAELAEALAEAAED Mb3469c|M.bovis_AF2122/97 ------------------LAADNPPGAVDPFAEDAADN------------ Rv3439c|M.tuberculosis_H37Rv ------------------LAADNPPGAVDPFAEDAADN------------ MLBr_01468|M.leprae_Br4923 --------LVQLTRKRLGTGLVEAFSTSCPNCTGRGILLHTDPANSTPMV MUL_3715|M.ulcerans_Agy99 --------LVQLTRKRLGTGLIEAFSTSCPHCSGRGILLHADPVDSAPTT MAB_0869c|M.abscessus_ATCC_199 ------------------PAPAEPAPAPEPAPAPAAAP------------ TH_3241|M.thermoresistible__bu ------------------SRSQRPGMDTEPAGTPEDSDSDADAGDGSVVD Mvan_1255|M.vanbaalenii_PYR-1 ------------------IPVYNLAATPDSWNNNGHASQRLKQARPDMFT Mflv_5098|M.gilvum_PYR-GCK ------------------FPIYNLAARSYFWNMSGTTNTAMETWRPGGFN MMAR_3402|M.marinum_M ------------------VPIYVVAAPPQPWNAFGATTNQLVSLYPGQFT MAV_3172|M.avium_104 ---KPE---SEETEAEAAE-----------------------------EP MSMEG_3222|M.smegmatis_MC2_155 FAVVPESAGSDEAEVAAAESAADAEDGPSDAESAEVPAEAAADDAVVSEP Mb3469c|M.bovis_AF2122/97 -ADDGDDAHPEEADEAAEPKE-------------------------ATEP Rv3439c|M.tuberculosis_H37Rv -ADDGDDAHPEEADEAAEPKE-------------------------ATEP MLBr_01468|M.leprae_Br4923 GRKSESGGRRSKRSKKNRSDE----TAVVKVPVHAPGEHPMFKAMAAGSS MUL_3715|M.ulcerans_Agy99 GRKADSGGRRNRRSKKNRAEEPSEKEAVAKVPTYAPGEHPMFKAMAASSS MAB_0869c|M.abscessus_ATCC_199 ------------------------------------------------EI TH_3241|M.thermoresistible__bu ETGVDETGPAPDSGPDSGPGS---------------------EPTEVTHP Mvan_1255|M.vanbaalenii_PYR-1 GVLVQGGHHSDSMQSASGIVQ------------------FMAYMATGFSS Mflv_5098|M.gilvum_PYR-GCK GVKLDDSSHGDAMTGGNVFVQ------------------VAMNLVTGWPK MMAR_3402|M.marinum_M GVEIVNGSHVDSMLGGNPLID------------------FAAQLLTGFSP MAV_3172|M.avium_104 E--SEETEAAEE---------------------------------PGE-- MSMEG_3222|M.smegmatis_MC2_155 AGTVDETEVAEEAAAEAADLEFESYDAELAEALAEAAEDMAVVVAPAETA Mb3469c|M.bovis_AF2122/97 D-EADEVDDADES-------------------------------VPAER- Rv3439c|M.tuberculosis_H37Rv D-EADEVDDADES-------------------------------VPAER- MLBr_01468|M.leprae_Br4923 SVVVGGEDESNESGTELTGKIDEPLEEQAVAGLDDVDQ-EDFD-TDEEDD MUL_3715|M.ulcerans_Agy99 SEAEHGDGEVEESGEELTAAVDDQTAVQVALDLGETEESEETDGTDETDD MAB_0869c|M.abscessus_ATCC_199 PLPAGVPDAADIG-------------------------------FAAGKA TH_3241|M.thermoresistible__bu TPPAEPTVAPDEPTSRPSTSAPAPAPDPDTPTQAPAVQAPPASQEPATRA Mvan_1255|M.vanbaalenii_PYR-1 PWNVEANEILTAG--------------------------------WINDM Mflv_5098|M.gilvum_PYR-GCK PANARAAELISAGWLDDMFTATSASG--------------FYGAPNATLS MMAR_3402|M.marinum_M PGATQAVYTLSSG--------------------------------WINDI MAV_3172|M.avium_104 --PEAEEPEEPEAEEP------------EEP-ETEEPEADSDEEPEEESG MSMEG_3222|M.smegmatis_MC2_155 ESDEAREPVETDATES------------EEPSEPEEPDAPEAVEAPEALD Mb3469c|M.bovis_AF2122/97 AQDVAEEATLPPVAEP------------PPPAAPPVAEPPPPVAAPAPPG Rv3439c|M.tuberculosis_H37Rv AQDVAEEATLPPVAEP------------PPPAAPPVAEPPPPVAAPAPPG MLBr_01468|M.leprae_Br4923 LDDDEELDDEEDLGDD-----------DEELDLDDDLDVDED-ESDSEAD MUL_3715|M.ulcerans_Agy99 FDDDSDDSDDSDEDDDTDETNDTDVDADEDEDTDDDSDEDEDTEDDDELD MAB_0869c|M.abscessus_ATCC_199 AFDAGPVASNGIPTSP------------EAVAGVVRHLPDPNNLPPGTTD TH_3241|M.thermoresistible__bu PATQAPATQAPATQAPG----------TQEPITQAPATEEPATQAPVTQG Mvan_1255|M.vanbaalenii_PYR-1 LDGTHTERLYRTSVSP------------FGLVTGAWIDPPSSVRVGALTA Mflv_5098|M.gilvum_PYR-GCK IETASGVATARVLPGPAEKLTFIDRLFTAGSMILFGIDFATCADTDAGPE MMAR_3402|M.marinum_M WAGADPLNPIYGIYGP----------------TGGYVAPGGQAIFLGPTA MAV_3172|M.avium_104 EAPEQPVAE----------EPEPAPQQPE-------------TKRRWGAR MSMEG_3222|M.smegmatis_MC2_155 ENADETRAE----------PAAPAAVATA-------------PVEPEKGR Mb3469c|M.bovis_AF2122/97 -APEPANGP----------SPEALSEGAT-------------PCEIAADE Rv3439c|M.tuberculosis_H37Rv -APEPANGP----------SPEALSEGAT-------------PCEIAADE MLBr_01468|M.leprae_Br4923 LDSADVLDR----------STLLIRNRSG----------FARPRRRRAAG MUL_3715|M.ulcerans_Agy99 DDLDDELDDDDSDSDDEDSESELTEPAAGRPAALEVTTIAERPRRRRAAG MAB_0869c|M.abscessus_ATCC_199 VAPGDSRGVS---------YLKDIVFAMQ-------------TQDVKASD TH_3241|M.thermoresistible__bu PATQAPRTVAPQTQAPETVAPQVEAPVTT------------MPQYPVGGG Mvan_1255|M.vanbaalenii_PYR-1 ATAGAGDVCP--------VTPTAVTCADP------------LPQSGAARG Mflv_5098|M.gilvum_PYR-GCK AQIGESAGIG---------RPNTALSLDG------------RAKAGQSIG MMAR_3402|M.marinum_M GIVLPA-------------------------------------------- MAV_3172|M.avium_104 LRDRLSGR-- MSMEG_3222|M.smegmatis_MC2_155 LRRWLRRNR- Mb3469c|M.bovis_AF2122/97 LPQAGP---- Rv3439c|M.tuberculosis_H37Rv LPQAGP---- MLBr_01468|M.leprae_Br4923 RPAGPPIHVD MUL_3715|M.ulcerans_Agy99 RPAGPPIHLG MAB_0869c|M.abscessus_ATCC_199 AILALAQR-- TH_3241|M.thermoresistible__bu SFGGGADGD- Mvan_1255|M.vanbaalenii_PYR-1 RAALV----- Mflv_5098|M.gilvum_PYR-GCK QQCVHG---- MMAR_3402|M.marinum_M ----------