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VIRDELRMDSPAQRGATRPSIPDESGSPMTSVDTAPAPPGPPHGGHDLEAELTVIPESAKTTDLRGQFWI WAGANIAPINWILGALGVTMGLGLFETIAVLVVGNAIGMSLFGLFVVIGQRTGVTGMVFSRAVFGRRGAY VPAAVQAVLCIGWCAVNTWIVLDLVMALLGRIGLVDPELSNNAARILVAGVIMTIQVAIAWFGYRVIAAF ERWTVPPTVAVLVAMTVVAWIGLDVDWAYAGDTTLTGAEHFTAITAVMTAIGIGWGITWLGYAGDYSRFV SAQVPARKLFAASALGQFIPVVWLGALGASLATLSTSSDPGEIIVDAYGALAIPVLLLVVHGPLATNILN IYTCAVSTQALDIKVNRRVLNVVIGVVAMACVVYFVLNGDFAQTIDAWLVGIVGWVSPWAAVMLVHWFGV ARRQVDAATLLTPPGESTLPTVRLSALFALAVGIVFTWLFMYGMVPVMQGPIAIALGGVDLSWLAGGLAA GTIYAALEIPRARRVRT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0862 | - | - | 100% (507) | permease for cytosine/purines, uracil, thiamine, allantoin |
| M. vanbaalenii PYR-1 | Mvan_3383 | - | 1e-26 | 25.46% (436) | permease for cytosine/purines, uracil, thiamine, allantoin |
| M. vanbaalenii PYR-1 | Mvan_0160 | - | 1e-15 | 23.26% (374) | permease for cytosine/purines, uracil, thiamine, allantoin |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0055 | - | 0.0 | 91.50% (459) | permease for cytosine/purines, uracil, thiamine, allantoin |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2025 | - | 2e-28 | 23.70% (460) | purine/cytosine permease |
| M. marinum M | MMAR_1212 | - | 3e-10 | 21.30% (507) | hypothetical protein MMAR_1212 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_6660 | - | 0.0 | 79.41% (476) | permease, cytosine/purines, uracil, thiamine, allantoin family |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2680 | - | 1e-09 | 22.16% (361) | hypothetical protein MUL_2680 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0862|M.vanbaalenii_PYR-1 MIRDELRMDSPAQRGATRPSIPDESGSPMTSVDTAPAPPGPPHGGHDLEA
Mflv_0055|M.gilvum_PYR-GCK --------------------------------------------MHDLEA
MSMEG_6660|M.smegmatis_MC2_155 ----------------------------MSAIATGSPVPG---TTESLES
MMAR_1212|M.marinum_M ---------------------MIDTTAPHSPVHSPSHGAGPANIKPDYHP
MUL_2680|M.ulcerans_Agy99 ---------------------MIDTTAPHSPVHSPSHGAGPANIKPDYHP
MAB_2025|M.abscessus_ATCC_1997 -------------------MDEIQACCSATSLIASRESVGRDRVGAIERA
..
Mvan_0862|M.vanbaalenii_PYR-1 ELT---VIPESAKTTDLRGQFWIWAGANIAPINWILGALGVTMGLGLFET
Mflv_0055|M.gilvum_PYR-GCK ELT---VIPESAKTTDLRGQFWIWAGANIAPINWILGALGVTMGLGLFET
MSMEG_6660|M.smegmatis_MC2_155 DLT---VIPESSRTTDLRGQFWIWAGANIAPINWILGALGVSMGLGLFET
MMAR_1212|M.marinum_M RLTNDDLAPLREQTWGTYNIFAFWMSDVHSVGGYVTAGSLFALGLASWQV
MUL_2680|M.ulcerans_Agy99 RLTNDDLAPLREQTWGTYNIFAFWMSDVHSVGGYVTAGSLFALGLASWQV
MAB_2025|M.abscessus_ATCC_1997 GID---YLPEAARGSSPKNLFAVFVGGNLAFSTIIFGWLPIVMGLTFWQA
: * : . . * .: . : : . . :** ::.
Mvan_0862|M.vanbaalenii_PYR-1 IAVLVVGNAIGMSLFGLFVVIGQRTGVTGMVFSRAVFGRRGAYVPAAVQA
Mflv_0055|M.gilvum_PYR-GCK IAVLVVGNAIGMSLFGTFVVIGQKTGVTGMVLSRMVFGRRGAYVPAAVQA
MSMEG_6660|M.smegmatis_MC2_155 IAVLAVGNAIGMSLFGTFVVIGQRTGVTGMVLARAVFGRRGAYVPAAVQA
MMAR_1212|M.marinum_M LVSLVIAITIVYFLCNLVARPSQATGVPYPVICRTAFGVLGANIPAIIRG
MUL_2680|M.ulcerans_Agy99 LVSLVIAITIVYFLCNLVARPSQATGVPYPVICRTAFGVLGANIPAIIRG
MAB_2025|M.abscessus_ATCC_1997 VSSSVTGLLIGLMLTAPMSLFGPRTGTNNPVSSGAHFGVRGRLIGSSLTL
: . . * * . . **. * . ** * : : :
Mvan_0862|M.vanbaalenii_PYR-1 VLCIGWCAVNTWIV---LDLVMALLG----RIGLVDPE--LSNNAARILV
Mflv_0055|M.gilvum_PYR-GCK ALCIGWCAVNTWIV---LDLVMALLG----RIGLVDPE--LSNHAARIVV
MSMEG_6660|M.smegmatis_MC2_155 VVCMGWCAVNTWIV---LDLVMALLG----RVGIVDPD--NASATPRILV
MMAR_1212|M.marinum_M LIAVAWYGIQTYLASAALDVVMIKLFPGLARYAVVEDYGFLGLPALGWAS
MUL_2680|M.ulcerans_Agy99 LIAVAWYGIQTYLASAALDVVMIKLFPGLARYAVVEDYGFLGLPALGWAS
MAB_2025|M.abscessus_ATCC_1997 MFALVYAAIAVWTSG---EALIAGAS------RLFGAP---QNHVAFLLG
..: : .: .: : :: :. .
Mvan_0862|M.vanbaalenii_PYR-1 AGVIMTIQVAIAWFGYRVIAAFERWTVPPTVAVLVAMT--VVAWIGLDVD
Mflv_0055|M.gilvum_PYR-GCK AGIIMTTQVVIAWFGYRLIAAFERWTVPPTVAVLVAMT--AVAWFGLDVD
MSMEG_6660|M.smegmatis_MC2_155 AAIIMVIQVVIAWFGYRVIAKFERWTVPPTVAVLVAMT--LVAWFGLDVD
MMAR_1212|M.marinum_M YLILWVLQACVFWRGMEAIRKFIDFCGPAVYVVMFALSGYLISKAGWAAI
MUL_2680|M.ulcerans_Agy99 YLILWVLQACVFWRGMEAIRKFIDFCGPAVYVVIFALSGYLISTAGWAAI
MAB_2025|M.abscessus_ATCC_1997 YGVIALEVILIALYGHATIVWAQKIIIP-LAVVVLALGVLAYAPNFHPMG
:: : * * * .*:.*: :
Mvan_0862|M.vanbaalenii_PYR-1 WAYAGDTTLTGAEHFTAITAVMTAIGIGWGITWLGYAGDYSRFVSAQVPA
Mflv_0055|M.gilvum_PYR-GCK WGYTGDAALTGAEHFTAITAVMTAIGIGWGITWLGYAGDYSRFVSSSVPA
MSMEG_6660|M.smegmatis_MC2_155 WGYSGVPTLTTTEHIAALSAVMTAIGIGWGITWLGYAADYSRFVSTSVPS
MMAR_1212|M.marinum_M DLNLGDVRYSGWDAIPVMLGAIALVVSYFSGPMLNFG-DFSRYGRSFGAV
MUL_2680|M.ulcerans_Agy99 DLNLGDVRYSGWDAIPVMLGAIALVVSYFSGPMLNFG-DFSRYGRSFGAV
MAB_2025|M.abscessus_ATCC_1997 SAQHGYALQEFWPTWLFAVTVSVGGPLSYAPSVGDYTRRISRSRYSDRQI
* . . :. . .: ** :
Mvan_0862|M.vanbaalenii_PYR-1 RKLFAASALGQFIPVVWLGALGASLAT-----LSTSSDPGEIIVDAYGAL
Mflv_0055|M.gilvum_PYR-GCK RKLFAASALGQFIPVVWLGALGATLAT-----LSASSDPGEIIVDAYGVL
MSMEG_6660|M.smegmatis_MC2_155 RKLFAVSALGQFIPVIWLGALGATLAT-----LSTSTDPGEIIVDAYGAL
MMAR_1212|M.marinum_M RKGNFLGLPLNFLLFSLLVVVTASLTVPVFGELITDPVQTVARIDSTFAI
MUL_2680|M.ulcerans_Agy99 RKGNFLGLPLNFLLFSLLVVVTASLTVPVFGELITDPVQTVARIDSTFAI
MAB_2025|M.abscessus_ATCC_1997 AVAVSAGIFLGLFSTATFGAFTASTFS-----APTASYVADMVATAPGWY
. :: : .. *: : . :
Mvan_0862|M.vanbaalenii_PYR-1 AIPVLLLVVHGPLATNILNIYTCAVSTQALDIKVNRRVLNVVIGVVAMAC
Mflv_0055|M.gilvum_PYR-GCK AIPVLLLVVHGPLATNILNIYTCAVSTQALDIHVNRRVLNIVIGVVAMAW
MSMEG_6660|M.smegmatis_MC2_155 AIPVLLLVVHGPLATNILNIYTCTVSTQALDIHINRRVLNVVIGVVAMAI
MMAR_1212|M.marinum_M ILGASTFTIATIGINIVANFISPAFDFSNVNPQRISWRTGGMIAAVGSAL
MUL_2680|M.ulcerans_Agy99 ILGASTFTIATIGINIVANFISPAFDFSNVNPQRIGWRTGGMIAAVGSAL
MAB_2025|M.abscessus_ATCC_1997 VVPLLILAVLGGCGQGVISIYSSGLDLESIVPRLNRTQTTLIASGIAVVL
: :.: : .: : .. . : : : . :. .
Mvan_0862|M.vanbaalenii_PYR-1 VVYFVLNGDFAQTIDAWLVGIVGWVSPWAAVMLVHWFGVARRQVDAATLL
Mflv_0055|M.gilvum_PYR-GCK VVYFVLNGDFAATIDAWLVGIVGWLAPWAAVMLVHWFGVARRQVDPATLL
MSMEG_6660|M.smegmatis_MC2_155 VVVFVLNGDFAATIDAWLVGIVGWLSPWAAVMLVHYFFIARRQVDAEALV
MMAR_1212|M.marinum_M ITPWNLY-NHPDVIHYTLETLGAFIGPLFGVLIADYYLVRKQHVVVDDLF
MUL_2680|M.ulcerans_Agy99 ITPWNLY-NHPDVIHYTLETLGAFIGPLFGVLIADYYLVRKQHVVVDDLF
MAB_2025|M.abscessus_ATCC_1997 MYLGVVVTDAIDSVTGMTVVLNSFAGSWVAINICGFFKANRGQYDPKALQ
: : : : : .: .. .: : :: : : *
Mvan_0862|M.vanbaalenii_PYR-1 TPPGES---TLPTVRLSALFALAVGIVFTWL-FMYGMVPVMQGPIAIALG
Mflv_0055|M.gilvum_PYR-GCK TPPNES---TLPAVRPSALISLAVGIVFTWL-FMYGMVPMMQGPIAVALG
MSMEG_6660|M.smegmatis_MC2_155 APPEAR---LLPMVRPTALAALAIGVVCTWM-FMYGMTPLLQGPAALALG
MMAR_1212|M.marinum_M SLSHDG---TYWYRKGYNPAAVIATAVS----AAIAMVPVLASDVYGMYT
MUL_2680|M.ulcerans_Agy99 SLSHDG---TYWYRKGYNPAAVIATAVS----AAIAMAPVLASDV-----
MAB_2025|M.abscessus_ATCC_1997 RFGQDGRGGLYWFSHGFNVRAVVPFIAGSGLGLLTVQNDLYQAPFANIAG
: :: . : .
Mvan_0862|M.vanbaalenii_PYR-1 GVDLSWLAGGLAAGTIYAALEIPRARRVRT--------
Mflv_0055|M.gilvum_PYR-GCK GVDLSWLAGGLAAGSLYAALEIPKARRA----------
MSMEG_6660|M.smegmatis_MC2_155 GVDLSWLAGGLTAGISYLALEAVRSRRTTVSG------
MMAR_1212|M.marinum_M AAEYSWFIGCGVALVVYYLLATRGRLAIAPPYHPVGAG
MUL_2680|M.ulcerans_Agy99 --------------------------------------
MAB_2025|M.abscessus_ATCC_1997 GIDVSLLLSVVVGGGLYWLAQVSWPAPRVVSSGSSA--