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TEPEDLDGGQGTQPAGYSDLADDTMSTMRPMATQAVFRPNFFDDEEDSDALHSGDTEPQLTTTTVTRHMS PTRRLGGGLVEIPRVPARDPLAALMTDPVVAESKRFCWNCGRPVGRSTKDGRALSEGWCPHCGSAYSFLP QLNVGDIVADQYEIKGCIAHGGLGWVYLAFDKNVNDRPVVLKGLVHSGDAEAQAIAMAERQFLAQVTHPG IVKIYNFVEHEDKHGNPVGYIVMEYVGGTSLKQATAQKGTRLPVAEAIGFMLEILPALGHLHSIGLVYND LKPENVMVTEDQLKLIDLGAVSRINSFGYLYGTPGYQAPEIVRTGPTVATDMYTVGRTLAALTLKLRTRK GRYVDGLPEDDPVLATYDSYGRLLRRAIDPDPRRRFQSAEEMSSQLMGVLREVVAKDTGVPRPGLSTVFS RSRSTFGVDLLVAHTDVYLDGQVHSEKLTAQEIVRALQVPLVDPTDVGATILSAIVLSQPVQTLDSLRAA RHGTLDSEGIDLSESVELPLMEVRALLDLGDVAKATRKLDDLAERVGWRWRLVWFRAVSELLTADYDSAT KHFNEVLDTLPGELAPKLALAATAELAGSADERSFYNTVWSTDNGVISAGFGLARAQSAAGDRDAAVRTL DEVPATSRHFTTARLTSAVTLLSGRSSSEITEQHIRDAARRVEALPDSEPRVLQIRALVLGTAMDWLADN TASTNHILGFPFTEHGLALGVEASLRSLARVAPTQAHRYALVDLANSVRPMSTF*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_0703 | - | - | 100% (755) | protein kinase |
M. vanbaalenii PYR-1 | Mvan_3539 | - | 3e-25 | 29.78% (319) | protein kinase |
M. vanbaalenii PYR-1 | Mvan_5401 | - | 4e-23 | 32.54% (295) | protein kinase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0418c | pknG | 0.0 | 80.43% (746) | serine/threonine-protein kinase PKNG (protein kinase G) |
M. gilvum PYR-GCK | Mflv_0202 | - | 0.0 | 90.37% (758) | protein kinase |
M. tuberculosis H37Rv | Rv0410c | pknG | 0.0 | 80.43% (746) | serine/threonine-protein kinase PKNG (protein kinase G) |
M. leprae Br4923 | MLBr_00304 | pknG | 0.0 | 78.43% (737) | putative serine-threonine protein kinase |
M. abscessus ATCC 19977 | MAB_4224 | - | 0.0 | 71.71% (753) | serine/threonine-protein kinase |
M. marinum M | MMAR_0713 | pknG | 0.0 | 79.09% (751) | serine/threonine-protein kinase PknG |
M. avium 104 | MAV_4751 | - | 0.0 | 79.21% (755) | serine/threonine protein kinase PknG |
M. smegmatis MC2 155 | MSMEG_0786 | - | 0.0 | 85.10% (765) | serine/threonine protein kinase |
M. thermoresistible (build 8) | TH_2307 | pknG | 0.0 | 83.99% (756) | SERINE/THREONINE-PROTEIN KINASE PKNG (PROTEIN KINASE G) |
M. ulcerans Agy99 | MUL_2810 | pknG | 0.0 | 80.72% (726) | serine/threonine-protein kinase PknG |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_0703|M.vanbaalenii_PYR-1 ----------------------------------------MTE-PEDLD- Mflv_0202|M.gilvum_PYR-GCK ----------------------------------------MSEYPDDIDP MSMEG_0786|M.smegmatis_MC2_155 --------------------------------------MTSPENPDLPDA TH_2307|M.thermoresistible__bu MPETEVNQNHDDARTGTPPAEPTVGSEPTVETRSAETTVGSEQKSTGPAP MLBr_00304|M.leprae_Br4923 ---------------------------------------MAES-MKREHM MAV_4751|M.avium_104 ---------------------------------------MAEPDNKSEQP Mb0418c|M.bovis_AF2122/97 -----------------------------------------------MAK Rv0410c|M.tuberculosis_H37Rv -----------------------------------------------MAK MMAR_0713|M.marinum_M ------------------------------MAEAVKKGLQDTSGTENPRP MUL_2810|M.ulcerans_Agy99 -------------------------------------------------- MAB_4224|M.abscessus_ATCC_1997 ------------------------------------------MSEDPEEP Mvan_0703|M.vanbaalenii_PYR-1 ------GGQGTQPAGYSDLADDTMSTMRPMATQAVFRPNFFDDEE-DSDA Mflv_0202|M.gilvum_PYR-GCK DTEPE-DGPGTQPAGFADLADDSMATLRPMATQAVFRPHFDDDDD-DSDA MSMEG_0786|M.smegmatis_MC2_155 DDAYVDSGPGTQPASLEDLDMDSASTMRPMATQAVYRPEFDDTD----GT TH_2307|M.thermoresistible__bu ETTSAGPTVGTQPASFDDLGLDTMSTIRPMATQAVFRPHLGDHP----DT MLBr_00304|M.leprae_Br4923 DHDTEDVGQAAQRADP----PSGTTEGRLQSTQAIFRPNFDDDDD-LLHI MAV_4751|M.avium_104 EPGTEQVGPGTQPAEVGDDAQGGAATGRLQATQALFRPDFDDDDDDFPHI Mb0418c|M.bovis_AF2122/97 ASETERSGPGTQPADAQ---TATSATVRPLSTQAVFRPDFGDEDN--FPH Rv0410c|M.tuberculosis_H37Rv ASETERSGPGTQPADAQ---TATSATVRPLSTQAVFRPDFGDEDN--FPH MMAR_0713|M.marinum_M AEDEQEAGPGTQPADVQ---TGAAAWSRPIGTQALFRPNFDDDDE--DDI MUL_2810|M.ulcerans_Agy99 ---------------MQ---TGAAAWSRPIGTQALFRPNFDDDDE--DDI MAB_4224|M.abscessus_ATCC_1997 DDTSADEGPGTQPASLADLDVDSASTMRPISTRAVFRPPDSTQPA----- : * .*:*::** Mvan_0703|M.vanbaalenii_PYR-1 L-HSGDTEPQLTTTTVTRHMSPTRRLGGGLVEIPRVPARDPLAALMTDPV Mflv_0202|M.gilvum_PYR-GCK LVHSGDTEPQDAATTITRHLSPTRRLGGGLVEIPRVPARDPLAALMTDPV MSMEG_0786|M.smegmatis_MC2_155 SRGTVVTEAYDQVTMATRALSPMRRLGGGLVEIPRVPERDPLTALMTNPV TH_2307|M.thermoresistible__bu E-GGDDTEPHDMAVTVARQMSPTRRLGGGLVEIPRVPTKDPLTALMTNPV MLBr_00304|M.leprae_Br4923 SVPSVDTEPQDRITPATRVLPPIRQLGGGLVEIRRVRDIDPLEALMTNPV MAV_4751|M.avium_104 SLGALDTDSADRMTVATRALPPVRQLGGGLVEIPRGRDIDPREALMTNPV Mb0418c|M.bovis_AF2122/97 PTLGPDTEPQDRMATTSRVRPPVRRLGGGLVEIPRAPDIDPLEALMTNPV Rv0410c|M.tuberculosis_H37Rv PTLGPDTEPQDRMATTSRVRPPVRRLGGGLVEIPRAPDIDPLEALMTNPV MMAR_0713|M.marinum_M TLGTLDMQPQGPLAAATRARLPVRRLGGGLVEIPRVPDTDPLKALMTDPV MUL_2810|M.ulcerans_Agy99 TLGTLDMQPQGPLAAATRARLPVRRLGGGLVEIPRVPDTDPLKALMTDPV MAB_4224|M.abscessus_ATCC_1997 --TQPTTQPEVRATTTRVLLSPTRRLGGGLVEIPRVPEIDPLEALMTNPV :. . * *:******** * ** ****:** Mvan_0703|M.vanbaalenii_PYR-1 VAESKRFCWNCGRPVGRSTKD------GRALSEGWCPHCGSAYSFLPQLN Mflv_0202|M.gilvum_PYR-GCK VAESKRFCWNCGRPVGRSTKD------GRALSEGWCPHCGSAYSFLPQLN MSMEG_0786|M.smegmatis_MC2_155 VAESKRFCWNCGKPVGRSTPD------GRALSEGWCPHCGSPYSFLPQLS TH_2307|M.thermoresistible__bu VAESKRFCWNCNRPVGRSKGA------TPAAIEGWCPHCGSPYSFLPQLN MLBr_00304|M.leprae_Br4923 VPESKRFCWNCGRPVGRSELEGQEADGAQGAKEGWCPYCGSPYSFLPQLS MAV_4751|M.avium_104 VPESKRFCWNCGKPVGRSTKK------SKGTSEGWCPHCGSAYSFLPQLN Mb0418c|M.bovis_AF2122/97 VPESKRFCWNCGRPVGRSDSE------TKGASEGWCPYCGSPYSFLPQLN Rv0410c|M.tuberculosis_H37Rv VPESKRFCWNCGRPVGRSDSE------TKGASEGWCPYCGSPYSFLPQLN MMAR_0713|M.marinum_M VPEAKRFCWNCGRPVGRSDSE------TKGASEGWCPYCGSPYSFLPQLS MUL_2810|M.ulcerans_Agy99 VPEAKRFCWNCGRPVGRSDSE------TKGASEGWCPYCGSPYSFLPQLS MAB_4224|M.abscessus_ATCC_1997 VEESKRFCWNCGKPVGRSTTD------SPAQSEGICPTCGSSFSFLPQLN * *:*******.:***** . ** ** ***.:******. Mvan_0703|M.vanbaalenii_PYR-1 VGDIVADQYEIKGCIAHGGLGWVYLAFDKNVNDRPVVLKGLVHSGDAEAQ Mflv_0202|M.gilvum_PYR-GCK PGDIVADQYEIKGCIAHGGLGWVYLAFDKNVNDRPVVLKGLVHSGDAEAQ MSMEG_0786|M.smegmatis_MC2_155 PGDIVADQYEIKGCIAHGGLGWVYLAFDKNVNDRPVVLKGLVHSGDAEAQ TH_2307|M.thermoresistible__bu PGDMVADQYEIKGCIAHGGLGWVYLAFDHNVNERPVVLKGLVHSGDAEAQ MLBr_00304|M.leprae_Br4923 PGDIVAGQYEVKGCIAHGGLGWVYLAFDHNVNDRPVVLKGLVHSGDAEAQ MAV_4751|M.avium_104 PGDIVANQYEVKGCIAHGGLGWVYLAVDHNVNDRPVVLKGLVHSGDAEAQ Mb0418c|M.bovis_AF2122/97 PGDIVAGQYEVKGCIAHGGLGWIYLALDRNVNGRPVVLKGLVHSGDAEAQ Rv0410c|M.tuberculosis_H37Rv PGDIVAGQYEVKGCIAHGGLGWIYLALDRNVNGRPVVLKGLVHSGDAEAQ MMAR_0713|M.marinum_M PGDTIAGQYEVKGCIAHGGMGWIYLALDRNVNDRPVVLKGLVHSGDAEAQ MUL_2810|M.ulcerans_Agy99 PGDTIAGQYEVKGCIAHGGMGWIYLALDRNVNDRPVVLKGLVHSGDAEAQ MAB_4224|M.abscessus_ATCC_1997 PGDVIAGQYAIKGCIAHGGLGWIYLAVDRNVNDRPVVLKGLVHSGDAEAQ ** :*.** :********:**:***.*:*** ***************** Mvan_0703|M.vanbaalenii_PYR-1 AIAMAERQFLAQVTHPGIVKIYNFVEHEDKHGNPVGYIVMEYVGGTSLKQ Mflv_0202|M.gilvum_PYR-GCK AIAMAERQFLAEVTHPGIVKIYNFVEHEDKHGNPVGYIVMEYVGGTSLKQ MSMEG_0786|M.smegmatis_MC2_155 AIAMAERQFLAEVTHPGIVKIYNFVEHEDKHGNPVGYIVMEYVGGTSLKQ TH_2307|M.thermoresistible__bu AIAMAERQFLAEVTHPGIVKIYNFVEHDDKHGNPVGYIVMEYVGGTSLKE MLBr_00304|M.leprae_Br4923 ASAVAERQFLAEVVHPQIVQIFNFVEHKDTSGDPVGYIVMEYIGGRSLKR MAV_4751|M.avium_104 AIAMAERQFLAEVVHPQIVQIFNFVEHVDRHGNPVGYIVMEYVGGQPLRH Mb0418c|M.bovis_AF2122/97 AMAMAERQFLAEVVHPSIVQIFNFVEHTDRHGDPVGYIVMEYVGGQSLKR Rv0410c|M.tuberculosis_H37Rv AMAMAERQFLAEVVHPSIVQIFNFVEHTDRHGDPVGYIVMEYVGGQSLKR MMAR_0713|M.marinum_M AIAMAERQFLAEVVHPSIVQIFNFVEHTDKHGDPVGYIVMEYVGGRSLKR MUL_2810|M.ulcerans_Agy99 AIAMAERQFLAEVVHPSIVQIFNFVEHTDKHGDPVGYIVMEYVGGRSLKR MAB_4224|M.abscessus_ATCC_1997 NIAMAERRFLAEVAHPSIVKIFNFVEHPDQHGNPVGYIVMEYVGGTSLKQ *:***:***:*.** **:*:***** * *:*********:** .*:. Mvan_0703|M.vanbaalenii_PYR-1 ATAQKGT---RLPVAEAIGFMLEILPALGHLHSIGLVYNDLKPENVMVTE Mflv_0202|M.gilvum_PYR-GCK ATLLKHSSRIRLPAAEAIGFMLEILPALGYLHSLGLVYNDLKPENIMVTE MSMEG_0786|M.smegmatis_MC2_155 ARG------AKLPVAEAIGYMLEILPALGYLHSIGLAYNDLKPENIMITE TH_2307|M.thermoresistible__bu ARD------KKLPVAEAIGYMLEILPALGYLHSIGLAYNDLKPENIMITE MLBr_00304|M.leprae_Br4923 GSKKGNV--EKLPVAEAIAYLLEILPALSYLHSIGLVYNDLKPENIMLTE MAV_4751|M.avium_104 G--KG----EKLPVSEAIAYVLEILPALGYLHSIGLVYNDLKPENIMLTE Mb0418c|M.bovis_AF2122/97 S--KG----QKLPVAEAIAYLLEILPALSYLHSIGLVYNDLKPENIMLTE Rv0410c|M.tuberculosis_H37Rv S--KG----QKLPVAEAIAYLLEILPALSYLHSIGLVYNDLKPENIMLTE MMAR_0713|M.marinum_M R--KG----EKLPVSEAIAYLLEILPALAYLHALGLVYNDLKPENIMLTE MUL_2810|M.ulcerans_Agy99 R--KG----EKLPVSEAIAYLLEILPALAYLHALGLVYNDLKPENIMLTE MAB_4224|M.abscessus_ATCC_1997 P--KG----NALPVAQAIAYMLEILPALGFLHSVGLTYNDLKPENIMITE **.::**.::*******..**::**.********:*:** Mvan_0703|M.vanbaalenii_PYR-1 DQLKLIDLGAVSRINSFGYLYGTPGYQAPEIVRTGPTVATDMYTVGRTLA Mflv_0202|M.gilvum_PYR-GCK DQLKIIDLGAVSRINSFGYLYGTPGYQAPEIVRTGPTVATDIYTVGRTLA MSMEG_0786|M.smegmatis_MC2_155 EQLKLIDLGAVSRLNSYGYLYGTPGYQAPEIVRTGPTVATDIYTVGRTLA TH_2307|M.thermoresistible__bu DQLKLIDLGAVSTINSFGYLYGTPGYQAPEIVRTGPTVQTDIYTVGRTLA MLBr_00304|M.leprae_Br4923 EQLKLIDLGAVSRINSFGCIYGTPGYQAPEIVRTGPTVATDIYTVGRTLA MAV_4751|M.avium_104 EQLELIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLA Mb0418c|M.bovis_AF2122/97 EQLKLIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLA Rv0410c|M.tuberculosis_H37Rv EQLKLIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLA MMAR_0713|M.marinum_M EQLKLIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLA MUL_2810|M.ulcerans_Agy99 EQLKLIDLGAVSRINSFGYLYVTPGFQAPEIVRTGPTVATDIYTVGRTLA MAB_4224|M.abscessus_ATCC_1997 EQLKLIDLGAVASINAYGNLYGTPGYQAPEISKTGPTVASDIYTVGRTLA :**::******: :*::* :* ***:***** :***** :*:******** Mvan_0703|M.vanbaalenii_PYR-1 ALTLKLRTRKGRYVDGLPEDDPVLATYDSYGRLLRRAIDPDPRRRFQSAE Mflv_0202|M.gilvum_PYR-GCK ALTMRLPTRKGRYLDGLPEDNPVLEEYDSFGRLLRRAIDPDPRRRFQTAE MSMEG_0786|M.smegmatis_MC2_155 ALTLSLRTRRGRYVDGLPSDDPVLETYDSYHRLLRRAIDPDPRRRFTSAE TH_2307|M.thermoresistible__bu ALTLKLPTRKGRYVDGLPEDDPVLAEYDSFARLLRRATDPDPRRRFASAE MLBr_00304|M.leprae_Br4923 ALTLNLRTRNGRYMDGLPEDDPVLTTYDSFARLLHRAINPDPRRRFSSAE MAV_4751|M.avium_104 ALTLNLPTRNGRYVDGIPDNDPVLGAYDSFRRLLRRATDPDPRRRFSSTE Mb0418c|M.bovis_AF2122/97 ALTLDLPTRNGRYVDGLPEDDPVLKTYDSYGRLLRRAIDPDPRQRFTTAE Rv0410c|M.tuberculosis_H37Rv ALTLDLPTRNGRYVDGLPEDDPVLKTYDSYGRLLRRAIDPDPRQRFTTAE MMAR_0713|M.marinum_M ALTLNLPTRNGRYLDGLPDDDPVLASYDSFGRLLRRAIDPDPRRRFASAE MUL_2810|M.ulcerans_Agy99 ALTLNLPTRNGRYLDGLPDDDPVLASYDSFGRLLRRAIDPDPRRRFASAE MAB_4224|M.abscessus_ATCC_1997 VLTLRMPTRKGRYKDGLPSDDPVLAKYDSYHRFLRRAIDPDPSARFGSAE .**: : **.*** **:*.::*** ***: *:*:** :*** ** ::* Mvan_0703|M.vanbaalenii_PYR-1 EMSSQLMGVLREVVAKDTGVPRPGLSTVFSRSRSTFGVDLLVAHTDVYLD Mflv_0202|M.gilvum_PYR-GCK ELSSQLMGVLREVVASDTGVPRPGLSTMFSPSRSTFGVDLLVAHTDVYLD MSMEG_0786|M.smegmatis_MC2_155 EMSSQLLGVLREVVATDTGVPRPGLSTVFSPSRSTFGVDLLVAHTDVYVD TH_2307|M.thermoresistible__bu EMSAQLLGVLREVVAKDTGVPRPGLSTVFSPTRSTFGIDLLLAHTDVYRD MLBr_00304|M.leprae_Br4923 EMSAQLMGVLREVVAQDTGVPRAGLSTIFSPSRSTFGVDLLVAHTDVYLD MAV_4751|M.avium_104 EMSAQLMGVLREVVAHDTGVPRPGLSTIFSPSRSTFGVDLLVAHTDVYLD Mb0418c|M.bovis_AF2122/97 EMSAQLTGVLREVVAQDTGVPRPGLSTIFSPSRSTFGVDLLVAHTDVYLD Rv0410c|M.tuberculosis_H37Rv EMSAQLTGVLREVVAQDTGVPRPGLSTIFSPSRSTFGVDLLVAHTDVYLD MMAR_0713|M.marinum_M EMSGQLMGVLREVVAQDTGVPRPGLSTVFSPSRSTFGVDLLVAHTDVYQD MUL_2810|M.ulcerans_Agy99 EMSGQLMGVLREVVAQDTGVPRPGLSTVFSPSRSTFGVDLLVAHTDVYQD MAB_4224|M.abscessus_ATCC_1997 EMATQLVGVLREVVALDSGTPRPGMSTLFSPSRSTFGVDLLVAHTDVYVD *:: ** ******** *:*.**.*:**:** :*****:***:****** * Mvan_0703|M.vanbaalenii_PYR-1 GQVHSEKLTAQEIVRALQVPLVDPTDVGATILSAIVLSQPVQTLDSLRAA Mflv_0202|M.gilvum_PYR-GCK GQVHSEKLTAQEIVKALQVPLVDPTDVGATVLSATLLSQPVQTLDSLRAV MSMEG_0786|M.smegmatis_MC2_155 GQVHSEKLTAQEIVRALPVPLVDRTDVGAPMLVASVLSEPVHTLDQLRAA TH_2307|M.thermoresistible__bu GQVHSEKLTAQEIVKALPVPLVDPADVGAPVLTASVLSEPVQTLDQLRAA MLBr_00304|M.leprae_Br4923 GRLHSEKLTAKDIVTALQVPLVDPTDVAAPVLQATVLSQPVQTLDSLRAA MAV_4751|M.avium_104 GQVHSEKLTAREIVTALQVPLVDPADVAAPVLQATVLSQPVQTLDSLRAA Mb0418c|M.bovis_AF2122/97 GQVHAEKLTANEIVTALSVPLVDPTDVAASVLQATVLSQPVQTLDSLRAA Rv0410c|M.tuberculosis_H37Rv GQVHAEKLTANEIVTALSVPLVDPTDVAASVLQATVLSQPVQTLDSLRAA MMAR_0713|M.marinum_M GQVHSEKLTAKEIVTALQVPLVDRTDVAASVLQATVLSQPVQTLDSLRAA MUL_2810|M.ulcerans_Agy99 GQVHSEKLTAKEIVTALQVPLVDRTDVAASVLQATVLSQPVQTLDSLRAA MAB_4224|M.abscessus_ATCC_1997 GLAHPPSLTAPDIVTALQVPLLDPTDVGAAILQATVLSQPIQTLESLKAA * *. .*** :** ** ***:* :**.*.:* * :**:*::**:.*:*. Mvan_0703|M.vanbaalenii_PYR-1 RHGTLDSEGIDLSESVELPLMEVRALLDLGDVAKATRKLDDLAERVGWRW Mflv_0202|M.gilvum_PYR-GCK RHGALDSDGVDLSQSVELPLMEVRALLDLGDVAKATRKLDDLAERVGWRW MSMEG_0786|M.smegmatis_MC2_155 RHGALDTEGIDLNESVELPLMEVRALLDLGDVAKATRKLEDLAARVGWRW TH_2307|M.thermoresistible__bu RHGALDSDGIDLSESVELPLMEVRALLDLGDVAKATRKLDDLAARVGWRW MLBr_00304|M.leprae_Br4923 RHGMLDAQGIDLAESVELPLMEVRALLDLGDVVKANRKLDDLADRVSCQW MAV_4751|M.avium_104 RHGTLDADGVELSESIELPLMEVRALLDLGDVAKATRKLDDLAERVGWQW Mb0418c|M.bovis_AF2122/97 RHGALDADGVDFSESVELPLMEVRALLDLGDVAKATRKLDDLAERVGWRW Rv0410c|M.tuberculosis_H37Rv RHGALDADGVDFSESVELPLMEVRALLDLGDVAKATRKLDDLAERVGWRW MMAR_0713|M.marinum_M RHGALDSDGADLSESVELPLMEVRALLDLGDVAKATRKLDDLSERVGWRW MUL_2810|M.ulcerans_Agy99 RHGALDSDGADLSESVELPLMEVRALLDLGDVAKATRKLDDLSERVGWRW MAB_4224|M.abscessus_ATCC_1997 RLGRIDADGVDLTESVELPLMEARALLDLGDVAKANSKLDQLEDRVGTPW * * :*::* :: :*:******.*********.**. **::* **. * Mvan_0703|M.vanbaalenii_PYR-1 RLVWFRAVSELLTADYDSATKHFNEVLDTLPGELAPKLALAATAELAGSA Mflv_0202|M.gilvum_PYR-GCK RLVWFRAVSELLTADYDSATKHFTQVLDTLPGELAPKLALAATAELAGAS MSMEG_0786|M.smegmatis_MC2_155 RLVWFKAVSEMLSADYDSATKHFTEVLDTLPGELAPKLALAATAELAGTA TH_2307|M.thermoresistible__bu RLVWFRAVAEMLSADYESAMKHFAEVLDTLPGELAPKLALAATAELAGSP MLBr_00304|M.leprae_Br4923 RLVWYRAVADLLTGDYASATKHFTEVLNTFPGELAPKLALAATAELAGES MAV_4751|M.avium_104 RLVWYKAVAELLTGDYDSATTHFTEVLDTFPGELAPKLALAATAELAGDV Mb0418c|M.bovis_AF2122/97 RLVWYRAVAELLTGDYDSATKHFTEVLDTFPGELAPKLALAATAELAGNT Rv0410c|M.tuberculosis_H37Rv RLVWYRAVAELLTGDYDSATKHFTEVLDTFPGELAPKLALAATAELAGNT MMAR_0713|M.marinum_M RLVWYRAVSELLTGAYDAAIKHFTEVLDTFPGELAPKLALAATAELAGYT MUL_2810|M.ulcerans_Agy99 RLVWYRAVSELLTGAYDAAIKHFTEVLDTFPGELAPKLALAATAELAGYT MAB_4224|M.abscessus_ATCC_1997 RLTWYRGMAALLNGDYDQATKHFTAVLDFLPGEIAPKMALAATAELAGDE **.*::.:: :*.. * * .** **: :***:***:********** Mvan_0703|M.vanbaalenii_PYR-1 DERSFYNTVWSTDNGVISAGFGLARAQSAAGDRDAAVRTLDEVPATSRHF Mflv_0202|M.gilvum_PYR-GCK DERTFYKTVWDTDHGVISAGFGLARALSAEGDREGAVRTLDEVPATSRHF MSMEG_0786|M.smegmatis_MC2_155 DELKFYKTVWSTDNGVISAGFGLARAQSVAGERDMAVQTLDEVPPTSRHF TH_2307|M.thermoresistible__bu EAGKFYNTVWSTDHGIISAAFGLARALAAEGDREGAVRVLDQVPATSRHF MLBr_00304|M.leprae_Br4923 DEHKFYRTVWHTNDGVVSAAFGLARFQSAEGDRTGAVCTLDEVPPTSRHF MAV_4751|M.avium_104 DEHRFYETVWKTNDGVISAAFGLARTLSAEGDRAAAVRTLDEVPATSRHF Mb0418c|M.bovis_AF2122/97 DEHKFYQTVWSTNDGVISAAFGLARARSAEGDRVGAVRTLDEVPPTSRHF Rv0410c|M.tuberculosis_H37Rv DEHKFYQTVWSTNDGVISAAFGLARARSAEGDRVGAVRTLDEVPPTSRHF MMAR_0713|M.marinum_M DGTNFYQTVWSTNDGVISAAFGLARTLSAQGERAGAVRTLDEVPPSSRHF MUL_2810|M.ulcerans_Agy99 DGTNFYQTVWSTNDGVISAAFGLARTLSAQGERAGAVRTLDEVPPSSRHF MAB_4224|M.abscessus_ATCC_1997 KNLDFYRTVWSTDNSVISAGYGLARTLAARGERAEAVRMLDNVPPTSRHF . **.*** *:..::**.:**** :. *:* ** **:**.:**** Mvan_0703|M.vanbaalenii_PYR-1 TTARLTSAVTLLSGRSSSEITEQHIRDAARRVEALPDSEPRVLQIRALVL Mflv_0202|M.gilvum_PYR-GCK TTARLTSAVTLLSGRSTSEITEEHIRSAARRVEALPDTEPRVLQIRALVL MSMEG_0786|M.smegmatis_MC2_155 TTARLTSAVTLLSGRSTSEITEQHIRDAARRVEALPDSEPRVLQIRALVL TH_2307|M.thermoresistible__bu PTARLTSAVTLLSGRSTSEITEKHIRDAARRVEALPDSEPRVLQIRALVL MLBr_00304|M.leprae_Br4923 TTARLTSAVTLLSGRSTNEITEQQIRDAARRVETLPPTEPRVLQIRALVL MAV_4751|M.avium_104 TTARLTSAVTLLSGRSKSEITEEEIRDAARRVEALPPTEPRVLQIRALVL Mb0418c|M.bovis_AF2122/97 TTARLTSAVTLLSGRSTSEVTEEQIRDAARRVEALPPTEPRVLQIRALVL Rv0410c|M.tuberculosis_H37Rv TTARLTSAVTLLSGRSTSEVTEEQIRDAARRVEALPPTEPRVLQIRALVL MMAR_0713|M.marinum_M TTARLTSAVTLLSGRSHGEITEEQIRDAARRVEALPPTEPRVLQIRALVL MUL_2810|M.ulcerans_Agy99 TTARLTSAVTLLSGRSHGEITEEQIRDAARRVEALPPTEPRVLQIRALVL MAB_4224|M.abscessus_ATCC_1997 TTARLTSAVTLLSGRTLSEVTEDDIREAARRVEALPETEPRVLQIRALVL .**************: .*:**..**.******:** :************ Mvan_0703|M.vanbaalenii_PYR-1 GTAMDWLADNTASTNHILGFPFTEHGLALGVEASLRSLARVAPTQAHRYA Mflv_0202|M.gilvum_PYR-GCK GTAMDWLADNTASTNHILGFPFTEHGLQLGVEASLRSLARVAPTQAHRYA MSMEG_0786|M.smegmatis_MC2_155 GTALDWLADNTASSNHILGFPFTEHGLKLGVEASLRALARIAPTQSHRYA TH_2307|M.thermoresistible__bu GTAMDWLADHNASTNHILGFPFTEHGLQLGVESSLRALARVAPTQAHRYA MLBr_00304|M.leprae_Br4923 GCAMDWLADNQASANHILGFPFTKHGLRLGVEASLRSLARVAPTQRHRYT MAV_4751|M.avium_104 GCAMDWLEDNKASTNHILGFPFTEHGLRLGVEAALRNLARVAPTQRHRYA Mb0418c|M.bovis_AF2122/97 GGALDWLKDNKASTNHILGFPFTSHGLRLGVEASLRSLARVAPTQRHRYT Rv0410c|M.tuberculosis_H37Rv GGALDWLKDNKASTNHILGFPFTSHGLRLGVEASLRSLARVAPTQRHRYT MMAR_0713|M.marinum_M GGAMDWLQDNEASTNHILGFPFTDHGLRLGVEASLRSLARVAPTQRHRYT MUL_2810|M.ulcerans_Agy99 GGAMDWLQDNEASTNHILGFPFTDHGLRLGVEASLRSLARVAPTQRHRYT MAB_4224|M.abscessus_ATCC_1997 GTALDWIKSNHSTGHHILGVPFTKRGLRQGVERCLRALARRATERAHRYA * *:**: .: :: :****.***.:** *** .** *** *. : ***: Mvan_0703|M.vanbaalenii_PYR-1 LVDLANSVRPMSTF Mflv_0202|M.gilvum_PYR-GCK LVDLANSVRPMSTF MSMEG_0786|M.smegmatis_MC2_155 LVDLANSVRPMSTF TH_2307|M.thermoresistible__bu LVDLANSVRPMSTF MLBr_00304|M.leprae_Br4923 LVDMANKVRPTSTL MAV_4751|M.avium_104 LVDMANKVRPTSTF Mb0418c|M.bovis_AF2122/97 LVDMANKVRPTSTF Rv0410c|M.tuberculosis_H37Rv LVDMANKVRPTSTF MMAR_0713|M.marinum_M LVDMANKVRPTSTF MUL_2810|M.ulcerans_Agy99 LVDMANKVRPTSTF MAB_4224|M.abscessus_ATCC_1997 LVDLANATRPTSLL ***:** .** * :