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AKASETERSGPGTQPADAQTATSATVRPLSTQAVFRPDFGDEDNFPHPTLGPDTEPQDRMATTSRVRPPV RRLGGGLVEIPRAPDIDPLEALMTNPVVPESKRFCWNCGRPVGRSDSETKGASEGWCPYCGSPYSFLPQL NPGDIVAGQYEVKGCIAHGGLGWIYLALDRNVNGRPVVLKGLVHSGDAEAQAMAMAERQFLAEVVHPSIV QIFNFVEHTDRHGDPVGYIVMEYVGGQSLKRSKGQKLPVAEAIAYLLEILPALSYLHSIGLVYNDLKPEN IMLTEEQLKLIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLAALTLDLPTRNGRYVD GLPEDDPVLKTYDSYGRLLRRAIDPDPRQRFTTAEEMSAQLTGVLREVVAQDTGVPRPGLSTIFSPSRST FGVDLLVAHTDVYLDGQVHAEKLTANEIVTALSVPLVDPTDVAASVLQATVLSQPVQTLDSLRAARHGAL DADGVDFSESVELPLMEVRALLDLGDVAKATRKLDDLAERVGWRWRLVWYRAVAELLTGDYDSATKHFTE VLDTFPGELAPKLALAATAELAGNTDEHKFYQTVWSTNDGVISAAFGLARARSAEGDRVGAVRTLDEVPP TSRHFTTARLTSAVTLLSGRSTSEVTEEQIRDAARRVEALPPTEPRVLQIRALVLGGALDWLKDNKASTN HILGFPFTSHGLRLGVEASLRSLARVAPTQRHRYTLVDMANKVRPTSTF*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0410c | pknG | - | 100% (750) | SERINE/THREONINE-PROTEIN KINASE PKNG (PROTEIN KINASE G) (STPK G) |
M. tuberculosis H37Rv | Rv2176 | pknL | 9e-18 | 27.12% (295) | transmembrane serine/threonine-protein kinase L |
M. tuberculosis H37Rv | Rv0015c | pknA | 4e-16 | 30.50% (200) | transmembrane serine/threonine-protein kinase A PKNA |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0418c | pknG | 0.0 | 100.00% (750) | serine/threonine-protein kinase PKNG (protein kinase G) |
M. gilvum PYR-GCK | Mflv_0202 | - | 0.0 | 80.80% (750) | protein kinase |
M. leprae Br4923 | MLBr_00304 | pknG | 0.0 | 83.18% (755) | putative serine-threonine protein kinase |
M. abscessus ATCC 19977 | MAB_4224 | - | 0.0 | 72.87% (741) | serine/threonine-protein kinase |
M. marinum M | MMAR_0713 | pknG | 0.0 | 87.17% (748) | serine/threonine-protein kinase PknG |
M. avium 104 | MAV_4751 | - | 0.0 | 85.47% (750) | serine/threonine protein kinase PknG |
M. smegmatis MC2 155 | MSMEG_0786 | - | 0.0 | 79.57% (744) | serine/threonine protein kinase |
M. thermoresistible (build 8) | TH_2307 | pknG | 0.0 | 79.12% (752) | SERINE/THREONINE-PROTEIN KINASE PKNG (PROTEIN KINASE G) |
M. ulcerans Agy99 | MUL_2810 | pknG | 0.0 | 87.70% (732) | serine/threonine-protein kinase PknG |
M. vanbaalenii PYR-1 | Mvan_0703 | - | 0.0 | 80.43% (746) | protein kinase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0202|M.gilvum_PYR-GCK ----------------------------------------MSEYPDDIDP Mvan_0703|M.vanbaalenii_PYR-1 ----------------------------------------MTE-PEDLD- MSMEG_0786|M.smegmatis_MC2_155 --------------------------------------MTSPENPDLPDA TH_2307|M.thermoresistible__bu MPETEVNQNHDDARTGTPPAEPTVGSEPTVETRSAETTVGSEQKSTGPAP Rv0410c|M.tuberculosis_H37Rv -----------------------------------------------MAK Mb0418c|M.bovis_AF2122/97 -----------------------------------------------MAK MMAR_0713|M.marinum_M ------------------------------MAEAVKKGLQDTSGTENPRP MUL_2810|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00304|M.leprae_Br4923 ---------------------------------------MAES-MKREHM MAV_4751|M.avium_104 ---------------------------------------MAEPDNKSEQP MAB_4224|M.abscessus_ATCC_1997 ------------------------------------------MSEDPEEP Mflv_0202|M.gilvum_PYR-GCK DTEPE-DGPGTQPAGFADLADDSMATLRPMATQAVFRPHFDDDDD-DSDA Mvan_0703|M.vanbaalenii_PYR-1 ------GGQGTQPAGYSDLADDTMSTMRPMATQAVFRPNFFDDEE-DSDA MSMEG_0786|M.smegmatis_MC2_155 DDAYVDSGPGTQPASLEDLDMDSASTMRPMATQAVYRPEFDDTD----GT TH_2307|M.thermoresistible__bu ETTSAGPTVGTQPASFDDLGLDTMSTIRPMATQAVFRPHLGDHP----DT Rv0410c|M.tuberculosis_H37Rv ASETERSGPGTQPADAQ---TATSATVRPLSTQAVFRPDFGDEDN--FPH Mb0418c|M.bovis_AF2122/97 ASETERSGPGTQPADAQ---TATSATVRPLSTQAVFRPDFGDEDN--FPH MMAR_0713|M.marinum_M AEDEQEAGPGTQPADVQ---TGAAAWSRPIGTQALFRPNFDDDDE--DDI MUL_2810|M.ulcerans_Agy99 ---------------MQ---TGAAAWSRPIGTQALFRPNFDDDDE--DDI MLBr_00304|M.leprae_Br4923 DHDTEDVGQAAQRADP----PSGTTEGRLQSTQAIFRPNFDDDDD-LLHI MAV_4751|M.avium_104 EPGTEQVGPGTQPAEVGDDAQGGAATGRLQATQALFRPDFDDDDDDFPHI MAB_4224|M.abscessus_ATCC_1997 DDTSADEGPGTQPASLADLDVDSASTMRPISTRAVFRPPDSTQPA----- : * .*:*::** Mflv_0202|M.gilvum_PYR-GCK LVHSGDTEPQDAATTITRHLSPTRRLGGGLVEIPRVPARDPLAALMTDPV Mvan_0703|M.vanbaalenii_PYR-1 L-HSGDTEPQLTTTTVTRHMSPTRRLGGGLVEIPRVPARDPLAALMTDPV MSMEG_0786|M.smegmatis_MC2_155 SRGTVVTEAYDQVTMATRALSPMRRLGGGLVEIPRVPERDPLTALMTNPV TH_2307|M.thermoresistible__bu E-GGDDTEPHDMAVTVARQMSPTRRLGGGLVEIPRVPTKDPLTALMTNPV Rv0410c|M.tuberculosis_H37Rv PTLGPDTEPQDRMATTSRVRPPVRRLGGGLVEIPRAPDIDPLEALMTNPV Mb0418c|M.bovis_AF2122/97 PTLGPDTEPQDRMATTSRVRPPVRRLGGGLVEIPRAPDIDPLEALMTNPV MMAR_0713|M.marinum_M TLGTLDMQPQGPLAAATRARLPVRRLGGGLVEIPRVPDTDPLKALMTDPV MUL_2810|M.ulcerans_Agy99 TLGTLDMQPQGPLAAATRARLPVRRLGGGLVEIPRVPDTDPLKALMTDPV MLBr_00304|M.leprae_Br4923 SVPSVDTEPQDRITPATRVLPPIRQLGGGLVEIRRVRDIDPLEALMTNPV MAV_4751|M.avium_104 SLGALDTDSADRMTVATRALPPVRQLGGGLVEIPRGRDIDPREALMTNPV MAB_4224|M.abscessus_ATCC_1997 --TQPTTQPEVRATTTRVLLSPTRRLGGGLVEIPRVPEIDPLEALMTNPV :. . * *:******** * ** ****:** Mflv_0202|M.gilvum_PYR-GCK VAESKRFCWNCGRPVGRSTKD------GRALSEGWCPHCGSAYSFLPQLN Mvan_0703|M.vanbaalenii_PYR-1 VAESKRFCWNCGRPVGRSTKD------GRALSEGWCPHCGSAYSFLPQLN MSMEG_0786|M.smegmatis_MC2_155 VAESKRFCWNCGKPVGRSTPD------GRALSEGWCPHCGSPYSFLPQLS TH_2307|M.thermoresistible__bu VAESKRFCWNCNRPVGRSKGA------TPAAIEGWCPHCGSPYSFLPQLN Rv0410c|M.tuberculosis_H37Rv VPESKRFCWNCGRPVGRSDSE------TKGASEGWCPYCGSPYSFLPQLN Mb0418c|M.bovis_AF2122/97 VPESKRFCWNCGRPVGRSDSE------TKGASEGWCPYCGSPYSFLPQLN MMAR_0713|M.marinum_M VPEAKRFCWNCGRPVGRSDSE------TKGASEGWCPYCGSPYSFLPQLS MUL_2810|M.ulcerans_Agy99 VPEAKRFCWNCGRPVGRSDSE------TKGASEGWCPYCGSPYSFLPQLS MLBr_00304|M.leprae_Br4923 VPESKRFCWNCGRPVGRSELEGQEADGAQGAKEGWCPYCGSPYSFLPQLS MAV_4751|M.avium_104 VPESKRFCWNCGKPVGRSTKK------SKGTSEGWCPHCGSAYSFLPQLN MAB_4224|M.abscessus_ATCC_1997 VEESKRFCWNCGKPVGRSTTD------SPAQSEGICPTCGSSFSFLPQLN * *:*******.:***** . ** ** ***.:******. Mflv_0202|M.gilvum_PYR-GCK PGDIVADQYEIKGCIAHGGLGWVYLAFDKNVNDRPVVLKGLVHSGDAEAQ Mvan_0703|M.vanbaalenii_PYR-1 VGDIVADQYEIKGCIAHGGLGWVYLAFDKNVNDRPVVLKGLVHSGDAEAQ MSMEG_0786|M.smegmatis_MC2_155 PGDIVADQYEIKGCIAHGGLGWVYLAFDKNVNDRPVVLKGLVHSGDAEAQ TH_2307|M.thermoresistible__bu PGDMVADQYEIKGCIAHGGLGWVYLAFDHNVNERPVVLKGLVHSGDAEAQ Rv0410c|M.tuberculosis_H37Rv PGDIVAGQYEVKGCIAHGGLGWIYLALDRNVNGRPVVLKGLVHSGDAEAQ Mb0418c|M.bovis_AF2122/97 PGDIVAGQYEVKGCIAHGGLGWIYLALDRNVNGRPVVLKGLVHSGDAEAQ MMAR_0713|M.marinum_M PGDTIAGQYEVKGCIAHGGMGWIYLALDRNVNDRPVVLKGLVHSGDAEAQ MUL_2810|M.ulcerans_Agy99 PGDTIAGQYEVKGCIAHGGMGWIYLALDRNVNDRPVVLKGLVHSGDAEAQ MLBr_00304|M.leprae_Br4923 PGDIVAGQYEVKGCIAHGGLGWVYLAFDHNVNDRPVVLKGLVHSGDAEAQ MAV_4751|M.avium_104 PGDIVANQYEVKGCIAHGGLGWVYLAVDHNVNDRPVVLKGLVHSGDAEAQ MAB_4224|M.abscessus_ATCC_1997 PGDVIAGQYAIKGCIAHGGLGWIYLAVDRNVNDRPVVLKGLVHSGDAEAQ ** :*.** :********:**:***.*:*** ***************** Mflv_0202|M.gilvum_PYR-GCK AIAMAERQFLAEVTHPGIVKIYNFVEHEDKHGNPVGYIVMEYVGGTSLKQ Mvan_0703|M.vanbaalenii_PYR-1 AIAMAERQFLAQVTHPGIVKIYNFVEHEDKHGNPVGYIVMEYVGGTSLKQ MSMEG_0786|M.smegmatis_MC2_155 AIAMAERQFLAEVTHPGIVKIYNFVEHEDKHGNPVGYIVMEYVGGTSLKQ TH_2307|M.thermoresistible__bu AIAMAERQFLAEVTHPGIVKIYNFVEHDDKHGNPVGYIVMEYVGGTSLKE Rv0410c|M.tuberculosis_H37Rv AMAMAERQFLAEVVHPSIVQIFNFVEHTDRHGDPVGYIVMEYVGGQSLKR Mb0418c|M.bovis_AF2122/97 AMAMAERQFLAEVVHPSIVQIFNFVEHTDRHGDPVGYIVMEYVGGQSLKR MMAR_0713|M.marinum_M AIAMAERQFLAEVVHPSIVQIFNFVEHTDKHGDPVGYIVMEYVGGRSLKR MUL_2810|M.ulcerans_Agy99 AIAMAERQFLAEVVHPSIVQIFNFVEHTDKHGDPVGYIVMEYVGGRSLKR MLBr_00304|M.leprae_Br4923 ASAVAERQFLAEVVHPQIVQIFNFVEHKDTSGDPVGYIVMEYIGGRSLKR MAV_4751|M.avium_104 AIAMAERQFLAEVVHPQIVQIFNFVEHVDRHGNPVGYIVMEYVGGQPLRH MAB_4224|M.abscessus_ATCC_1997 NIAMAERRFLAEVAHPSIVKIFNFVEHPDQHGNPVGYIVMEYVGGTSLKQ *:***:***:*.** **:*:***** * *:*********:** .*:. Mflv_0202|M.gilvum_PYR-GCK ATLLKHSSRIRLPAAEAIGFMLEILPALGYLHSLGLVYNDLKPENIMVTE Mvan_0703|M.vanbaalenii_PYR-1 ATAQKGT---RLPVAEAIGFMLEILPALGHLHSIGLVYNDLKPENVMVTE MSMEG_0786|M.smegmatis_MC2_155 ARG------AKLPVAEAIGYMLEILPALGYLHSIGLAYNDLKPENIMITE TH_2307|M.thermoresistible__bu ARD------KKLPVAEAIGYMLEILPALGYLHSIGLAYNDLKPENIMITE Rv0410c|M.tuberculosis_H37Rv S--KG----QKLPVAEAIAYLLEILPALSYLHSIGLVYNDLKPENIMLTE Mb0418c|M.bovis_AF2122/97 S--KG----QKLPVAEAIAYLLEILPALSYLHSIGLVYNDLKPENIMLTE MMAR_0713|M.marinum_M R--KG----EKLPVSEAIAYLLEILPALAYLHALGLVYNDLKPENIMLTE MUL_2810|M.ulcerans_Agy99 R--KG----EKLPVSEAIAYLLEILPALAYLHALGLVYNDLKPENIMLTE MLBr_00304|M.leprae_Br4923 GSKKGNV--EKLPVAEAIAYLLEILPALSYLHSIGLVYNDLKPENIMLTE MAV_4751|M.avium_104 G--KG----EKLPVSEAIAYVLEILPALGYLHSIGLVYNDLKPENIMLTE MAB_4224|M.abscessus_ATCC_1997 P--KG----NALPVAQAIAYMLEILPALGFLHSVGLTYNDLKPENIMITE **.::**.::*******..**::**.********:*:** Mflv_0202|M.gilvum_PYR-GCK DQLKIIDLGAVSRINSFGYLYGTPGYQAPEIVRTGPTVATDIYTVGRTLA Mvan_0703|M.vanbaalenii_PYR-1 DQLKLIDLGAVSRINSFGYLYGTPGYQAPEIVRTGPTVATDMYTVGRTLA MSMEG_0786|M.smegmatis_MC2_155 EQLKLIDLGAVSRLNSYGYLYGTPGYQAPEIVRTGPTVATDIYTVGRTLA TH_2307|M.thermoresistible__bu DQLKLIDLGAVSTINSFGYLYGTPGYQAPEIVRTGPTVQTDIYTVGRTLA Rv0410c|M.tuberculosis_H37Rv EQLKLIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLA Mb0418c|M.bovis_AF2122/97 EQLKLIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLA MMAR_0713|M.marinum_M EQLKLIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLA MUL_2810|M.ulcerans_Agy99 EQLKLIDLGAVSRINSFGYLYVTPGFQAPEIVRTGPTVATDIYTVGRTLA MLBr_00304|M.leprae_Br4923 EQLKLIDLGAVSRINSFGCIYGTPGYQAPEIVRTGPTVATDIYTVGRTLA MAV_4751|M.avium_104 EQLELIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLA MAB_4224|M.abscessus_ATCC_1997 EQLKLIDLGAVASINAYGNLYGTPGYQAPEISKTGPTVASDIYTVGRTLA :**::******: :*::* :* ***:***** :***** :*:******** Mflv_0202|M.gilvum_PYR-GCK ALTMRLPTRKGRYLDGLPEDNPVLEEYDSFGRLLRRAIDPDPRRRFQTAE Mvan_0703|M.vanbaalenii_PYR-1 ALTLKLRTRKGRYVDGLPEDDPVLATYDSYGRLLRRAIDPDPRRRFQSAE MSMEG_0786|M.smegmatis_MC2_155 ALTLSLRTRRGRYVDGLPSDDPVLETYDSYHRLLRRAIDPDPRRRFTSAE TH_2307|M.thermoresistible__bu ALTLKLPTRKGRYVDGLPEDDPVLAEYDSFARLLRRATDPDPRRRFASAE Rv0410c|M.tuberculosis_H37Rv ALTLDLPTRNGRYVDGLPEDDPVLKTYDSYGRLLRRAIDPDPRQRFTTAE Mb0418c|M.bovis_AF2122/97 ALTLDLPTRNGRYVDGLPEDDPVLKTYDSYGRLLRRAIDPDPRQRFTTAE MMAR_0713|M.marinum_M ALTLNLPTRNGRYLDGLPDDDPVLASYDSFGRLLRRAIDPDPRRRFASAE MUL_2810|M.ulcerans_Agy99 ALTLNLPTRNGRYLDGLPDDDPVLASYDSFGRLLRRAIDPDPRRRFASAE MLBr_00304|M.leprae_Br4923 ALTLNLRTRNGRYMDGLPEDDPVLTTYDSFARLLHRAINPDPRRRFSSAE MAV_4751|M.avium_104 ALTLNLPTRNGRYVDGIPDNDPVLGAYDSFRRLLRRATDPDPRRRFSSTE MAB_4224|M.abscessus_ATCC_1997 VLTLRMPTRKGRYKDGLPSDDPVLAKYDSYHRFLRRAIDPDPSARFGSAE .**: : **.*** **:*.::*** ***: *:*:** :*** ** ::* Mflv_0202|M.gilvum_PYR-GCK ELSSQLMGVLREVVASDTGVPRPGLSTMFSPSRSTFGVDLLVAHTDVYLD Mvan_0703|M.vanbaalenii_PYR-1 EMSSQLMGVLREVVAKDTGVPRPGLSTVFSRSRSTFGVDLLVAHTDVYLD MSMEG_0786|M.smegmatis_MC2_155 EMSSQLLGVLREVVATDTGVPRPGLSTVFSPSRSTFGVDLLVAHTDVYVD TH_2307|M.thermoresistible__bu EMSAQLLGVLREVVAKDTGVPRPGLSTVFSPTRSTFGIDLLLAHTDVYRD Rv0410c|M.tuberculosis_H37Rv EMSAQLTGVLREVVAQDTGVPRPGLSTIFSPSRSTFGVDLLVAHTDVYLD Mb0418c|M.bovis_AF2122/97 EMSAQLTGVLREVVAQDTGVPRPGLSTIFSPSRSTFGVDLLVAHTDVYLD MMAR_0713|M.marinum_M EMSGQLMGVLREVVAQDTGVPRPGLSTVFSPSRSTFGVDLLVAHTDVYQD MUL_2810|M.ulcerans_Agy99 EMSGQLMGVLREVVAQDTGVPRPGLSTVFSPSRSTFGVDLLVAHTDVYQD MLBr_00304|M.leprae_Br4923 EMSAQLMGVLREVVAQDTGVPRAGLSTIFSPSRSTFGVDLLVAHTDVYLD MAV_4751|M.avium_104 EMSAQLMGVLREVVAHDTGVPRPGLSTIFSPSRSTFGVDLLVAHTDVYLD MAB_4224|M.abscessus_ATCC_1997 EMATQLVGVLREVVALDSGTPRPGMSTLFSPSRSTFGVDLLVAHTDVYVD *:: ** ******** *:*.**.*:**:** :*****:***:****** * Mflv_0202|M.gilvum_PYR-GCK GQVHSEKLTAQEIVKALQVPLVDPTDVGATVLSATLLSQPVQTLDSLRAV Mvan_0703|M.vanbaalenii_PYR-1 GQVHSEKLTAQEIVRALQVPLVDPTDVGATILSAIVLSQPVQTLDSLRAA MSMEG_0786|M.smegmatis_MC2_155 GQVHSEKLTAQEIVRALPVPLVDRTDVGAPMLVASVLSEPVHTLDQLRAA TH_2307|M.thermoresistible__bu GQVHSEKLTAQEIVKALPVPLVDPADVGAPVLTASVLSEPVQTLDQLRAA Rv0410c|M.tuberculosis_H37Rv GQVHAEKLTANEIVTALSVPLVDPTDVAASVLQATVLSQPVQTLDSLRAA Mb0418c|M.bovis_AF2122/97 GQVHAEKLTANEIVTALSVPLVDPTDVAASVLQATVLSQPVQTLDSLRAA MMAR_0713|M.marinum_M GQVHSEKLTAKEIVTALQVPLVDRTDVAASVLQATVLSQPVQTLDSLRAA MUL_2810|M.ulcerans_Agy99 GQVHSEKLTAKEIVTALQVPLVDRTDVAASVLQATVLSQPVQTLDSLRAA MLBr_00304|M.leprae_Br4923 GRLHSEKLTAKDIVTALQVPLVDPTDVAAPVLQATVLSQPVQTLDSLRAA MAV_4751|M.avium_104 GQVHSEKLTAREIVTALQVPLVDPADVAAPVLQATVLSQPVQTLDSLRAA MAB_4224|M.abscessus_ATCC_1997 GLAHPPSLTAPDIVTALQVPLLDPTDVGAAILQATVLSQPIQTLESLKAA * *. .*** :** ** ***:* :**.*.:* * :**:*::**:.*:*. Mflv_0202|M.gilvum_PYR-GCK RHGALDSDGVDLSQSVELPLMEVRALLDLGDVAKATRKLDDLAERVGWRW Mvan_0703|M.vanbaalenii_PYR-1 RHGTLDSEGIDLSESVELPLMEVRALLDLGDVAKATRKLDDLAERVGWRW MSMEG_0786|M.smegmatis_MC2_155 RHGALDTEGIDLNESVELPLMEVRALLDLGDVAKATRKLEDLAARVGWRW TH_2307|M.thermoresistible__bu RHGALDSDGIDLSESVELPLMEVRALLDLGDVAKATRKLDDLAARVGWRW Rv0410c|M.tuberculosis_H37Rv RHGALDADGVDFSESVELPLMEVRALLDLGDVAKATRKLDDLAERVGWRW Mb0418c|M.bovis_AF2122/97 RHGALDADGVDFSESVELPLMEVRALLDLGDVAKATRKLDDLAERVGWRW MMAR_0713|M.marinum_M RHGALDSDGADLSESVELPLMEVRALLDLGDVAKATRKLDDLSERVGWRW MUL_2810|M.ulcerans_Agy99 RHGALDSDGADLSESVELPLMEVRALLDLGDVAKATRKLDDLSERVGWRW MLBr_00304|M.leprae_Br4923 RHGMLDAQGIDLAESVELPLMEVRALLDLGDVVKANRKLDDLADRVSCQW MAV_4751|M.avium_104 RHGTLDADGVELSESIELPLMEVRALLDLGDVAKATRKLDDLAERVGWQW MAB_4224|M.abscessus_ATCC_1997 RLGRIDADGVDLTESVELPLMEARALLDLGDVAKANSKLDQLEDRVGTPW * * :*::* :: :*:******.*********.**. **::* **. * Mflv_0202|M.gilvum_PYR-GCK RLVWFRAVSELLTADYDSATKHFTQVLDTLPGELAPKLALAATAELAGAS Mvan_0703|M.vanbaalenii_PYR-1 RLVWFRAVSELLTADYDSATKHFNEVLDTLPGELAPKLALAATAELAGSA MSMEG_0786|M.smegmatis_MC2_155 RLVWFKAVSEMLSADYDSATKHFTEVLDTLPGELAPKLALAATAELAGTA TH_2307|M.thermoresistible__bu RLVWFRAVAEMLSADYESAMKHFAEVLDTLPGELAPKLALAATAELAGSP Rv0410c|M.tuberculosis_H37Rv RLVWYRAVAELLTGDYDSATKHFTEVLDTFPGELAPKLALAATAELAGNT Mb0418c|M.bovis_AF2122/97 RLVWYRAVAELLTGDYDSATKHFTEVLDTFPGELAPKLALAATAELAGNT MMAR_0713|M.marinum_M RLVWYRAVSELLTGAYDAAIKHFTEVLDTFPGELAPKLALAATAELAGYT MUL_2810|M.ulcerans_Agy99 RLVWYRAVSELLTGAYDAAIKHFTEVLDTFPGELAPKLALAATAELAGYT MLBr_00304|M.leprae_Br4923 RLVWYRAVADLLTGDYASATKHFTEVLNTFPGELAPKLALAATAELAGES MAV_4751|M.avium_104 RLVWYKAVAELLTGDYDSATTHFTEVLDTFPGELAPKLALAATAELAGDV MAB_4224|M.abscessus_ATCC_1997 RLTWYRGMAALLNGDYDQATKHFTAVLDFLPGEIAPKMALAATAELAGDE **.*::.:: :*.. * * .** **: :***:***:********** Mflv_0202|M.gilvum_PYR-GCK DERTFYKTVWDTDHGVISAGFGLARALSAEGDREGAVRTLDEVPATSRHF Mvan_0703|M.vanbaalenii_PYR-1 DERSFYNTVWSTDNGVISAGFGLARAQSAAGDRDAAVRTLDEVPATSRHF MSMEG_0786|M.smegmatis_MC2_155 DELKFYKTVWSTDNGVISAGFGLARAQSVAGERDMAVQTLDEVPPTSRHF TH_2307|M.thermoresistible__bu EAGKFYNTVWSTDHGIISAAFGLARALAAEGDREGAVRVLDQVPATSRHF Rv0410c|M.tuberculosis_H37Rv DEHKFYQTVWSTNDGVISAAFGLARARSAEGDRVGAVRTLDEVPPTSRHF Mb0418c|M.bovis_AF2122/97 DEHKFYQTVWSTNDGVISAAFGLARARSAEGDRVGAVRTLDEVPPTSRHF MMAR_0713|M.marinum_M DGTNFYQTVWSTNDGVISAAFGLARTLSAQGERAGAVRTLDEVPPSSRHF MUL_2810|M.ulcerans_Agy99 DGTNFYQTVWSTNDGVISAAFGLARTLSAQGERAGAVRTLDEVPPSSRHF MLBr_00304|M.leprae_Br4923 DEHKFYRTVWHTNDGVVSAAFGLARFQSAEGDRTGAVCTLDEVPPTSRHF MAV_4751|M.avium_104 DEHRFYETVWKTNDGVISAAFGLARTLSAEGDRAAAVRTLDEVPATSRHF MAB_4224|M.abscessus_ATCC_1997 KNLDFYRTVWSTDNSVISAGYGLARTLAARGERAEAVRMLDNVPPTSRHF . **.*** *:..::**.:**** :. *:* ** **:**.:**** Mflv_0202|M.gilvum_PYR-GCK TTARLTSAVTLLSGRSTSEITEEHIRSAARRVEALPDTEPRVLQIRALVL Mvan_0703|M.vanbaalenii_PYR-1 TTARLTSAVTLLSGRSSSEITEQHIRDAARRVEALPDSEPRVLQIRALVL MSMEG_0786|M.smegmatis_MC2_155 TTARLTSAVTLLSGRSTSEITEQHIRDAARRVEALPDSEPRVLQIRALVL TH_2307|M.thermoresistible__bu PTARLTSAVTLLSGRSTSEITEKHIRDAARRVEALPDSEPRVLQIRALVL Rv0410c|M.tuberculosis_H37Rv TTARLTSAVTLLSGRSTSEVTEEQIRDAARRVEALPPTEPRVLQIRALVL Mb0418c|M.bovis_AF2122/97 TTARLTSAVTLLSGRSTSEVTEEQIRDAARRVEALPPTEPRVLQIRALVL MMAR_0713|M.marinum_M TTARLTSAVTLLSGRSHGEITEEQIRDAARRVEALPPTEPRVLQIRALVL MUL_2810|M.ulcerans_Agy99 TTARLTSAVTLLSGRSHGEITEEQIRDAARRVEALPPTEPRVLQIRALVL MLBr_00304|M.leprae_Br4923 TTARLTSAVTLLSGRSTNEITEQQIRDAARRVETLPPTEPRVLQIRALVL MAV_4751|M.avium_104 TTARLTSAVTLLSGRSKSEITEEEIRDAARRVEALPPTEPRVLQIRALVL MAB_4224|M.abscessus_ATCC_1997 TTARLTSAVTLLSGRTLSEVTEDDIREAARRVEALPETEPRVLQIRALVL .**************: .*:**..**.******:** :************ Mflv_0202|M.gilvum_PYR-GCK GTAMDWLADNTASTNHILGFPFTEHGLQLGVEASLRSLARVAPTQAHRYA Mvan_0703|M.vanbaalenii_PYR-1 GTAMDWLADNTASTNHILGFPFTEHGLALGVEASLRSLARVAPTQAHRYA MSMEG_0786|M.smegmatis_MC2_155 GTALDWLADNTASSNHILGFPFTEHGLKLGVEASLRALARIAPTQSHRYA TH_2307|M.thermoresistible__bu GTAMDWLADHNASTNHILGFPFTEHGLQLGVESSLRALARVAPTQAHRYA Rv0410c|M.tuberculosis_H37Rv GGALDWLKDNKASTNHILGFPFTSHGLRLGVEASLRSLARVAPTQRHRYT Mb0418c|M.bovis_AF2122/97 GGALDWLKDNKASTNHILGFPFTSHGLRLGVEASLRSLARVAPTQRHRYT MMAR_0713|M.marinum_M GGAMDWLQDNEASTNHILGFPFTDHGLRLGVEASLRSLARVAPTQRHRYT MUL_2810|M.ulcerans_Agy99 GGAMDWLQDNEASTNHILGFPFTDHGLRLGVEASLRSLARVAPTQRHRYT MLBr_00304|M.leprae_Br4923 GCAMDWLADNQASANHILGFPFTKHGLRLGVEASLRSLARVAPTQRHRYT MAV_4751|M.avium_104 GCAMDWLEDNKASTNHILGFPFTEHGLRLGVEAALRNLARVAPTQRHRYA MAB_4224|M.abscessus_ATCC_1997 GTALDWIKSNHSTGHHILGVPFTKRGLRQGVERCLRALARRATERAHRYA * *:**: .: :: :****.***.:** *** .** *** *. : ***: Mflv_0202|M.gilvum_PYR-GCK LVDLANSVRPMSTF Mvan_0703|M.vanbaalenii_PYR-1 LVDLANSVRPMSTF MSMEG_0786|M.smegmatis_MC2_155 LVDLANSVRPMSTF TH_2307|M.thermoresistible__bu LVDLANSVRPMSTF Rv0410c|M.tuberculosis_H37Rv LVDMANKVRPTSTF Mb0418c|M.bovis_AF2122/97 LVDMANKVRPTSTF MMAR_0713|M.marinum_M LVDMANKVRPTSTF MUL_2810|M.ulcerans_Agy99 LVDMANKVRPTSTF MLBr_00304|M.leprae_Br4923 LVDMANKVRPTSTL MAV_4751|M.avium_104 LVDMANKVRPTSTF MAB_4224|M.abscessus_ATCC_1997 LVDLANATRPTSLL ***:** .** * :