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TESAEQFRDAPIFDADQHMYETPEALTKHLPQRYSRAVQFANFGRHTRIVINNRVSDFIPNPTFERVAAP GAHEKFFAGENTEGLTLREMQGPAIEAPAATRNPADRVAELDRQGVREALNYPTLASLIEHATADDPELT LAVIHALNQWMLEHWGFDYQGRVFSTPIINLSEVDGAQRELDYVLTHGAKVALIKPGPVNGLRGWRSPAL PEFDPFWRDVEAAGLPIVLHASYPPLDDYVGKWEPPHTQNFMAMSAFRWMVLGHREIADMITSLICHGTL TRFPKLRIASVENGSSWIFPLFNDFDELAKKMPQNFGEHPLDVFRRNIWVSPFWEGCVSDVVNTVGWDKV MFGSDYPHPEGLAEPKGFWKYAEGMDVRRTYDFMGDNARRFMGLPIANPDPAAARPPALTTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0383 | - | - | 100% (413) | amidohydrolase 2 |
| M. vanbaalenii PYR-1 | Mvan_2602 | - | 8e-98 | 46.19% (381) | amidohydrolase 2 |
| M. vanbaalenii PYR-1 | Mvan_4134 | - | 2e-91 | 42.56% (383) | amidohydrolase 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0351 | - | 0.0 | 93.70% (413) | amidohydrolase 2 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0299 | - | 7e-05 | 20.90% (244) | putative amidohydrolase (aminocarboxymuconate-semialdehyde |
| M. marinum M | MMAR_3988 | - | 3e-98 | 44.16% (394) | metal-dependent hydrolase |
| M. avium 104 | MAV_1851 | - | 0.0 | 74.69% (407) | amidohydrolase family protein |
| M. smegmatis MC2 155 | MSMEG_2235 | - | 0.0 | 84.56% (408) | amidohydrolase family protein |
| M. thermoresistible (build 8) | TH_0536 | - | 1e-102 | 46.40% (403) | amidohydrolase family protein |
| M. ulcerans Agy99 | MUL_3849 | - | 1e-96 | 43.91% (394) | metal-dependent hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0383|M.vanbaalenii_PYR-1 MTESAEQFRDAPIFDADQHMYETPEALTKHLPQRYSRAVQFANFGRHTRI
Mflv_0351|M.gilvum_PYR-GCK MPEPAPQFRDAPIFDADQHMYETPDALTKFLPDRYTRAVQYGQFGRHTRI
MSMEG_2235|M.smegmatis_MC2_155 ---MTEQFTDAPIFDADQHMYETAEALTKFLPERYRRAVQYAQIGRHTRV
MAV_1851|M.avium_104 ---MTTQFTEAPIFDADQHMYETPDALTKFLPDKFRPKVQFVQIGRHTRI
MMAR_3988|M.marinum_M ---MPSRELPFPVFDADNHMYEPQEALTKFLPDKRRHVIDYVQVRGRTKI
MUL_3849|M.ulcerans_Agy99 ---MPSRELPFPVFDADNHMYEPQEALTKFLPDKRKHVIDYVQVRGRTKI
TH_0536|M.thermoresistible__bu ---MPSRELPYPVFDADNHFYEPQEALTKFLPEHRKGVIDYIDVRGRTKI
MAB_0299|M.abscessus_ATCC_1997 --------MTSVRIDIHAHLWS----------------------------
:* . *::.
Mvan_0383|M.vanbaalenii_PYR-1 VINNRVSDFIPNPTFERVAAPGAHEKFFAGENTEGLTLREMQGPAIEAPA
Mflv_0351|M.gilvum_PYR-GCK VINNRVSDFIPNPTFERVAAPGAHEKFFAGENTEGLTLREMQGPAIEAPA
MSMEG_2235|M.smegmatis_MC2_155 VINNRVTDFIPNPTFERVAAPGAHEKFFAGENTEGLTLREMQGKPIEAPA
MAV_1851|M.avium_104 AIRNKITDYMPNPTFERVAAPGAHEKFYSGQNTEGLSMREMSGRGIETPP
MMAR_3988|M.marinum_M VVRGQISDYIPNPTFEVVARPGAQEEYFR-NGSRGKSYREVMGEPMKAIP
MUL_3849|M.ulcerans_Agy99 VVRGQISDYIPNPTFEVVARPGAQEEHFR-NGSGGKSYREVMGEPMKAIP
TH_0536|M.thermoresistible__bu VVRNQISDYIPNPTFEVVARPGAQEEYFK-YGSGGKSFREVMGKPMKAIP
MAB_0299|M.abscessus_ATCC_1997 ------------------------DEYLSLLDGYGRPATDVHR-GLGAGA
::. . * . :: : : .
Mvan_0383|M.vanbaalenii_PYR-1 ATRNPADRVAELDRQGVREALNYPTLASLIEHATADDPELTLAVIHALNQ
Mflv_0351|M.gilvum_PYR-GCK ATRNPADRVAELDRQGVREALNYPTLASLIEHATADDPELTLAVIHALNQ
MSMEG_2235|M.smegmatis_MC2_155 ATRNPEDRIAELDRQGVVEALIYPTLGSLVEHSSADDPQLTLAIIHALNE
MAV_1851|M.avium_104 AARNPEDRIAELDRQGVDACLNYPTLANLVEHASAEDPDLTVAIIHALNQ
MMAR_3988|M.marinum_M AFREPGPRLEVMDELGLDYALMFPTLASLVEERMKDDPEMTHDVIHALNQ
MUL_3849|M.ulcerans_Agy99 AFREPGPRLEVMDELGLDYALMFPTLASLVEERMKDDPEMTHDVIHALNQ
TH_0536|M.thermoresistible__bu AFRDPEARLEVLDGLGLDYTIMFPTLASLVEERMKDDPDLILDVIHALNQ
MAB_0299|M.abscessus_ATCC_1997 TRDDLDGRFELMDEAGVDLQILTATPAS----PHFEDQAAAVASARFIND
: : *. :* *: : .* .. :* : :*:
Mvan_0383|M.vanbaalenii_PYR-1 WMLEHWGFDYQGRVFSTPIINLSEVDGAQRELDYVLTHGAKVALIKPGPV
Mflv_0351|M.gilvum_PYR-GCK WMAEHWTFDYQGRVFSTPIINLSEVDGAQRELEYILTQGARVALIKPGPV
MSMEG_2235|M.smegmatis_MC2_155 WILEHWTFNHADRLFTTPIINLSEVEAAQRELAWILEHGAKAALIKPGPV
MAV_1851|M.avium_104 WMLEHWGFTYANRIYSTPVLNLGLVDEARRELEYILENGAKVALIKPAPV
MMAR_3988|M.marinum_M WMYETWSFNYKDRIFATPVITLPIVDRALEELEWCLQRGARTVLVRPAPV
MUL_3849|M.ulcerans_Agy99 WMYETWSFNYKDRIFATPVITLPIVDRALEELEWCLQRGARTVLVRPAPV
TH_0536|M.thermoresistible__bu WMYETWQFDYEGRILSTPVINLSVVDRALEELEWCLERGAKTILVRPAPV
MAB_0299|M.abscessus_ATCC_1997 -EYAKLSSEYPGRFGALASLPLPHVPAALEELARAIDELGMYGASITTSV
: .*. : . : * * * .** : . . . .*
Mvan_0383|M.vanbaalenii_PYR-1 NGLRGWRSPALPEFDPFWRDVEAAGLPIVLHASYPPLDDYVGKWEPPHTQ
Mflv_0351|M.gilvum_PYR-GCK NGLRGWRSPALPEFDPFWRDVESAGLPIVLHASYPPLDDYVGKWEPPYTQ
MSMEG_2235|M.smegmatis_MC2_155 NGLHGWRSPALPEFDPFWRDVEAAGLPIVLHASFPPLDDYINKWEPAHTQ
MAV_1851|M.avium_104 YGYKGWRSPALPEFDPFWRDVEDAGLPIVLHASQPPLQEYIEKWEPADTA
MMAR_3988|M.marinum_M PGYRGSRSFGFEEFDPFWQACIKAGIPVSMHASDSGYSEFLNVWEPGDEF
MUL_3849|M.ulcerans_Agy99 PGYRGSRSFGFKEFDPFWQACIKAGIPVSMHASDSGYSEFLNVWEPGDEF
TH_0536|M.thermoresistible__bu PGYRGTRSLGLPEFDPFWDACVKAGIPVCMHASDSGYAQYLNDWEPADEF
MAB_0299|M.abscessus_ATCC_1997 LG----RSIADPIFDPLYAELNRRRAVLFVHPAG-----------CGAES
* ** . ***:: : :*.:
Mvan_0383|M.vanbaalenii_PYR-1 NFMAMSAFRWMVLGHREIADMITSLICHGTLTRFPKLRIASVENGSSWIF
Mflv_0351|M.gilvum_PYR-GCK NFMTQSAFRWMVLGHREIADMITALICHGTLTRFPKLRIASVENGSSWIF
MSMEG_2235|M.smegmatis_MC2_155 NFMTQSAFRWMVLGHREIADMLTALICHGTLTRFPRLRIASVENGSSWIF
MAV_1851|M.avium_104 NAFEMSAFKWTALGHREIADMITSLICHGTLTRFPKLRIASVENGSAWIK
MMAR_3988|M.marinum_M LPFKPTAFRMLAMGKRPIEDAMGALVCHGALSRNPELRILSIENGADWVP
MUL_3849|M.ulcerans_Agy99 LPFKPTAFRMLAMSKRPIEDAMGALVCHGALSRNPELRILSIKNGADWVP
TH_0536|M.thermoresistible__bu LPFRPTAFRMVAMGKRPIEDTMAALVCHGALSRNPDLRILSVENGASWVP
MAB_0299|M.abscessus_ATCC_1997 SLITDHSLTWSIGAPIEDTVAIMHLIVAGVPSRYPDMKIVTCHLGGALPM
: :: . : *: *. :* * ::* : . *.
Mvan_0383|M.vanbaalenii_PYR-1 PLFNDFDELAKKMPQNFGEHPLDVFRRNIWVSPFWEGC--VSDVVNTVGW
Mflv_0351|M.gilvum_PYR-GCK PLFNDFEELAKKMPQNFGEHPLDVFRRNIWVSPFWEGC--VSDVVTTVGW
MSMEG_2235|M.smegmatis_MC2_155 PLFRDFADLYKKMPQNFPEHPHDVFRRNIWVSPFWEGC--VADVVETVGW
MAV_1851|M.avium_104 PLFDDLEMTYKKMPQNFPEHPHDVFRRNCWVSPFWEGS--VADVVETVGW
MMAR_3988|M.marinum_M TLFKGLKGVYKKMPNAFMEDPIEAFKRCVYISPFWEDR--FAEIVKMVGT
MUL_3849|M.ulcerans_Agy99 TLFKGLKGVYKKMPNAFMEDPIEAFKRCVYISPFWEDR--FVEIVKMVGT
TH_0536|M.thermoresistible__bu YLFYQFKDVYKKMPQEFAEDPIEAFKRCVYVAPFWEDN--FKEIADLIGI
MAB_0299|M.abscessus_ATCC_1997 VLERAHRQVTEWEATQCPEAPRDAARRLWYDTVGHDHTPALRAAVASLGV
* : . * * :. :* : : : . . :*
Mvan_0383|M.vanbaalenii_PYR-1 DKVMFGSDYPHPEGLAEPKGFWKYAEGMDVRR--TYDFMGDNARRFMGLP
Mflv_0351|M.gilvum_PYR-GCK DKVMFGSDYPHPEGLPEPKGFWKYAEGMDVRR--TYDFMGDNARRFMGLP
MSMEG_2235|M.smegmatis_MC2_155 DKVLFGSDYPHPEGLAEPKGFWKYAEGMDIRR--TYDFMGDNARRFMGLP
MAV_1851|M.avium_104 DRVLFGSDWPHPEGLAEPKRYWQYAEGMDKRR--TYDFMGDNARRFMGLP
MMAR_3988|M.marinum_M DRVVFGSDWPHPEGLKDPISFVDELAGFPPED--VAKIMGGNMMEVMKIG
MUL_3849|M.ulcerans_Agy99 DRVVFGSDWPHPEGLKDPISFVDELAGFPPED--VAKIMGGNMMDVMKIG
TH_0536|M.thermoresistible__bu DRVIFGSDWPHPEGLADPIRLVDELEEHGLDDEGIRKVMGANLIELFGVE
MAB_0299|M.abscessus_ATCC_1997 DRLIFGSDFPYQAGPRYVSSATYIEEGLSAED--ASAILDHNGAELLGLT
*:::****:*: * .:. * .: :
Mvan_0383|M.vanbaalenii_PYR-1 IANPDPAAARPPALTTA-
Mflv_0351|M.gilvum_PYR-GCK IANPDPEAARPPALSTA-
MSMEG_2235|M.smegmatis_MC2_155 IANPDPDAVKPPALTASS
MAV_1851|M.avium_104 IANPDPDAVKPPALVNA-
MMAR_3988|M.marinum_M TPAPQPVNA---------
MUL_3849|M.ulcerans_Agy99 TAAPKPVNA---------
TH_0536|M.thermoresistible__bu NKKVHNPNVPALEIPA--
MAB_0299|M.abscessus_ATCC_1997 GV----------------