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GQLSHRVDIPFPLFDADNHLYEPPEAMTKYLPKEYKDVVQYVEVNGRTKIALKGQISNYIPNPTFSVVAK PGAWEEYFKFGNPDGKSKRELFGEPMKAIPAFFEPEPRIKVMDELGIQRSLMFPTLASLIEERLSDDPVA IHVIIHALNEWLHEVWGFNYQGRIFTTPVITLPIVEKAIEELEWAVKRGARAILIRPAPVPGFRGPRSFA LPEFDPFWERVVHHDIFVGMHSSDSGYSRYTSEWDGAAQEMLPFQTNAMSILNEWRPIQDAVASWVIHGA LFRFPKLKVGIVEAGSKWMFPLLDSMAEVYKKAPEAFLGNPIEEIKNRIYVSPFYEEGIDDLINLIGVDQ VLYGSDWPHPEGLAEPTHYVTALEHLSVEDQAKIMGGNLGRLVTT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4134 | - | - | 100% (396) | amidohydrolase 2 |
| M. vanbaalenii PYR-1 | Mvan_2602 | - | e-124 | 54.95% (384) | amidohydrolase 2 |
| M. vanbaalenii PYR-1 | Mvan_0383 | - | 2e-91 | 42.56% (383) | amidohydrolase 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2524 | - | 0.0 | 98.74% (396) | amidohydrolase 2 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0299 | - | 2e-07 | 24.15% (294) | putative amidohydrolase (aminocarboxymuconate-semialdehyde |
| M. marinum M | MMAR_4689 | - | 0.0 | 74.68% (387) | hypothetical protein MMAR_4689 |
| M. avium 104 | MAV_0970 | - | 0.0 | 84.81% (395) | amidohydrolase family protein |
| M. smegmatis MC2 155 | MSMEG_4773 | - | 0.0 | 94.95% (396) | amidohydrolase family protein |
| M. thermoresistible (build 8) | TH_0534 | - | 0.0 | 90.89% (395) | amidohydrolase family protein |
| M. ulcerans Agy99 | MUL_0308 | - | 0.0 | 74.16% (387) | hypothetical protein MUL_0308 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4134|M.vanbaalenii_PYR-1 MGQLSHRVDIPFPLFDADNHLYEPPEAMTKYLPKEYKDVVQYVEVNGRTK
Mflv_2524|M.gilvum_PYR-GCK MGQLSHRVEIPFPLFDADNHLYEPPEAMTKYLPKEYKDIVQYVEINGRTK
MSMEG_4773|M.smegmatis_MC2_155 MGQLSHRVDIPFPLFDADNHLYEPPEAMTKYLPKDYKDVVQYVEVNGRTK
TH_0534|M.thermoresistible__bu MGQLSHRVELPFPLFDADNHLYEPPEAMTKYLPKDYKDVVQYVQVNGRTK
MAV_0970|M.avium_104 MGQLSHREDVPFPIFDADNHLYEPPEALTKFLPKEYKDFVQYVQINGRTK
MMAR_4689|M.marinum_M ----MSSAALSYPLFDADNHLYETEESLTKYLPKQYRGVIQYVQVNGRTK
MUL_0308|M.ulcerans_Agy99 ----MSSAALSYPLFDADNHLYETEESLTKYLPKQYRGVIQYVQVNGRTK
MAB_0299|M.abscessus_ATCC_1997 ---------MTSVRIDIHAHLWS-------------DEYLSLLDGYGRPA
:. :* . **:. :. :: **.
Mvan_4134|M.vanbaalenii_PYR-1 IALKGQISNYIPNPTFSVVAKPGAWEEYFKFGNPDGKSKRELFGEPMKAI
Mflv_2524|M.gilvum_PYR-GCK IALKGQISNYIPNPTFSVVAKPGAWEEYFKFGNPDGKSKRELFGEPMKAI
MSMEG_4773|M.smegmatis_MC2_155 IAINGQISNYIPNPTFSVVAKPGAWEEYFKFGNPDGKSKRELFGEPMRSI
TH_0534|M.thermoresistible__bu IAIRGQISNYIPNPTFEVVARPGAWEEYFKFGNPEGKSKRELFGEPMRSI
MAV_0970|M.avium_104 IALRGVISNYIPNPTFEVVARPGAWEEYFKYGNPEGKSKRELFGEPMRAI
MMAR_4689|M.marinum_M IAIRGQISDYIPNPTFEVVARPGAMEEYFRIGNPDGKSRREIFGEPMRSI
MUL_0308|M.ulcerans_Agy99 IAIRGQISDYIPNPTFEVVARPGAMEEYFRIGNPDGKSRREIFGEPMRSI
MAB_0299|M.abscessus_ATCC_1997 TDVHRGLG--------------------------AGATRDDLDG------
:. :. * :: :: *
Mvan_4134|M.vanbaalenii_PYR-1 PAFFEPEPRIKVMDELGIQRSLMFPTLASLIEERLSDDPVAIHVIIHALN
Mflv_2524|M.gilvum_PYR-GCK PAFFEPEPRIKVMDELGIQRSLMFPTLASLIEERLSDDPVAIHVIIHALN
MSMEG_4773|M.smegmatis_MC2_155 PAFFEPEPRLELMDQLGVDRSLMFPTLASLIEERLRDDPVAIHVIIHSLN
TH_0534|M.thermoresistible__bu PAFFEPGPRLELMDELGVDRTLMFPTLASLIEERLRDDPVAIHVLIHALN
MAV_0970|M.avium_104 PAFFEPGPRLEKMNELGLDRTLMFPTLASLIEERLRDDPVAIHVLIHALN
MMAR_4689|M.marinum_M PAFREPGPRLELMNELGVDRSLMFPTLASLIEERMRDDPLLIHIVVHALN
MUL_0308|M.ulcerans_Agy99 PAFREPGPRLELMNELGVDRSLMFPTLASLIEERMRDDPLLIHIVVHALN
MAB_0299|M.abscessus_ATCC_1997 --------RFELMDEAGVDLQILTATPAS---PHFEDQAAAVASARFIND
*:: *:: *:: :: .* ** :: *:. : . :
Mvan_4134|M.vanbaalenii_PYR-1 EWLHEVWGFNYQGRIFTTPVITLPIVEKAIEELEWAVKRGARAILIRPAP
Mflv_2524|M.gilvum_PYR-GCK EWLHEVWGFNYQGRIFTTPVITLPIVEKAIEELEWAVKRGARAILIRPAP
MSMEG_4773|M.smegmatis_MC2_155 LWLDEVWGFNYKNRIFTTPVITLPIVEKAIEELEWAVSRGARAILIRPAP
TH_0534|M.thermoresistible__bu QWLDEVWGFNYKNRIFTTPVITLPIVEKAIEELEWCVKRGARAILIRPAP
MAV_0970|M.avium_104 QWLDEVWGFNYQNRIFTTPVITLPIVEKAIEELEWVVKRGARAILVRPAP
MMAR_4689|M.marinum_M EWLHEEWGFRYQDRIFTVPVVSLPIVEKAIEELDWVVERGARAVLVRPAP
MUL_0308|M.ulcerans_Agy99 EWLHEEWGFRYQDRIFTVPVVSLPIVEKAIEELDWVVERGARAVLVRPAP
MAB_0299|M.abscessus_ATCC_1997 EYAKLSS--EYPGRFGALASLPLPHVPAALEELARAIDELG----MYGAS
: . .* .*: : . :.** * *:*** :.. . : *.
Mvan_4134|M.vanbaalenii_PYR-1 VPGFRGPRSFALPEFDPFWERVVHHDIFVGMHSSDSGYSRYTSEWDGAAQ
Mflv_2524|M.gilvum_PYR-GCK VPGFRGPRSFALPEFDPFWERVVHHDIFVGMHSSDSGYSRYTSEWDGAAQ
MSMEG_4773|M.smegmatis_MC2_155 VPGFRGPRSFALPEFDPFWERVVHHDVFVGMHSSDSGYSRYTSEWDGAAQ
TH_0534|M.thermoresistible__bu VPGFRGPRSFALPEFDPFWERVVEYDVFVGMHSSDSGYSRYTSEWDGSQQ
MAV_0970|M.avium_104 VPGFRGPRSFALPEFDPFWERVVEYDVLVGMHSSDSGYSRYTSEWDGADQ
MMAR_4689|M.marinum_M VPGYRGPRSFALPEFDPFWHRCVEHDVLVAMHSSDSGYARYTAEWDGGDK
MUL_0308|M.ulcerans_Agy99 VPGYRGPRSFALPEFDPFWHRCVEHDVLVAMHSSASGYARYTAEWDGGDK
MAB_0299|M.abscessus_ATCC_1997 ITTSVLGRSIADPIFDPLYAELNRRRAVLFVHPAGCG----------AES
:. **:* * ***:: . . .: :*.: .* . .
Mvan_4134|M.vanbaalenii_PYR-1 EMLPFQTNAMSILNEWRPIQD--AVASWVIHGALFRFPKLKVGIVEAGSK
Mflv_2524|M.gilvum_PYR-GCK EMLPFQTNAMSILNEWRPIQD--AVASWVIHGALFRFPKLKVGIVEAGSK
MSMEG_4773|M.smegmatis_MC2_155 EMLPFQTNAMSILNEWRPIQD--AVASWVIHGALFRHPKLKVGIVEAGSK
TH_0534|M.thermoresistible__bu EMLPFQTNAMAILNEWRPIQD--AVASWVIHGALFRHPKLKVGIVEAGSK
MAV_0970|M.avium_104 EMLPFQTNAMGILNEWRPIQD--SVASWVIHGALYRHPKLKVAIVEAGSK
MMAR_4689|M.marinum_M EMLPFQTNAFSMLNEWRPVQD--AVASWVIHGALYRVPRLKVAVIEAGSK
MUL_0308|M.ulcerans_Agy99 EMLPFQTNAFSMLNEWRPVQD--AVASWVIHGALYRVPRLKVAVIEAGSK
MAB_0299|M.abscessus_ATCC_1997 SLITDHSLTWSIG---APIEDTVAIMHLIVAGVPSRYPDMKIVTCHLGGA
.::. :: : .: *::* :: :: *. * * :*: . *.
Mvan_4134|M.vanbaalenii_PYR-1 WMFPLLDSMAEVYKKAPEAFLG-NPIEEIKNRIYVSPFYEEG--IDDLIN
Mflv_2524|M.gilvum_PYR-GCK WMFPLLDSMAEVYKKAPEAFLG-NPMEEIKNRIYVSPFYEEG--IDDLIN
MSMEG_4773|M.smegmatis_MC2_155 WMFPLLDSMAEVYKKAPEAFLG-NPIEEIKNRIYVSPFYEEG--IDDLIN
TH_0534|M.thermoresistible__bu WMFPLLDSMAEVYKKAPEAFLG-NPIEEIKNRIYVSPFYEEG--IDELIN
MAV_0970|M.avium_104 WMTPLLDGLAEVFRKAPEAFPS-DPVEMVKNRIHVSPFFEDG--IDDLVN
MMAR_4689|M.marinum_M WLFPLLDQLADVYKKTPESFPGGDPVEEIKNRIHVSPFYEDG--IADLIK
MUL_0308|M.ulcerans_Agy99 WLFPLLDQLADVYKKTPESFPGGDPVEEIKNRIHISPFYEDG--IADLIK
MAB_0299|M.abscessus_ATCC_1997 LPMVLERAHRQVTEWEATQCPE-APRDAARRLWYDTVGHDHTPALRAAVA
* :* . . * : :. : : .:. : :
Mvan_4134|M.vanbaalenii_PYR-1 LIGVDQVLYGSDWPHPEGLAEPTHYVTALEHLSVEDQAKIMGGNLGRLVT
Mflv_2524|M.gilvum_PYR-GCK LIGVDQVLYGSDWPHPEGLAEPTHYVTALEHLAVEDQAKIMGGNLGRLVT
MSMEG_4773|M.smegmatis_MC2_155 LIGVDQVLYGSDWPHPEGLAEPTHYVTALEHLSVEDQAKIMGGNLGRLVT
TH_0534|M.thermoresistible__bu LVGVDQVLYGSDWPHPEGLAEPTHYVTALEHLSLEDQAKIMGGNLSRLVT
MAV_0970|M.avium_104 LVGVDQVLYGSDWPHPEGLAEPTYYVNALSHLPVEDQAKIMGGNLGRLVT
MMAR_4689|M.marinum_M LIGTDRVLYGSDYPHPEGLAQPRHYADALQDLSVDDQAKIMGGNLARLMS
MUL_0308|M.ulcerans_Agy99 LIGTDRVLYGSDYPHPEGLAQPRHYADALQDLSVDDQAKIMGGNLARLMS
MAB_0299|M.abscessus_ATCC_1997 SLGVDRLIFGSDFPYQAGPRYVSSATYIEEGLSAEDASAILDHNGAELLG
:*.*::::***:*: * . . *. :* : *:. * ..*:
Mvan_4134|M.vanbaalenii_PYR-1 T---
Mflv_2524|M.gilvum_PYR-GCK T---
MSMEG_4773|M.smegmatis_MC2_155 T---
TH_0534|M.thermoresistible__bu V---
MAV_0970|M.avium_104 V---
MMAR_4689|M.marinum_M V---
MUL_0308|M.ulcerans_Agy99 V---
MAB_0299|M.abscessus_ATCC_1997 LTGV