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LIHSTDKRVRTVTFDRAEAMNAFNEALYHATADALLDAASDDDVAVVVLTGQGRAFCAGTDLQEMLDRDP SIPFTEGAHGFRRLIDNLIDFPKPLVCAVNGIAVGLGTTLLGYADLVFMSTSARLKCPFTSLGIAPEAAS TYLLPELIGRQNAAWILMSSEWISAEEALAMGLAWKVCEPAELMPTAFDYAERLAAQPLESLVAVKQAMG APHAADIRAALALENALLDRLVGGPANTQALNGFAAARASRER*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0340 | - | - | 100% (254) | enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_3046 | - | 9e-78 | 60.32% (247) | enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_4207 | - | 3e-25 | 33.99% (253) | enoyl-CoA hydratase/isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2855 | echA16 | 3e-23 | 32.57% (218) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_3325 | - | 1e-80 | 61.83% (241) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv2831 | echA16 | 3e-23 | 32.57% (218) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 5e-19 | 25.82% (244) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0905 | - | 1e-21 | 29.05% (241) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_2759 | echA8_6 | 2e-84 | 64.61% (243) | enoyl-CoA hydratase, EchA8_6 |
| M. avium 104 | MAV_2835 | - | 1e-82 | 64.02% (239) | enoyl-CoA hydratase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_0340 | - | 2e-82 | 60.24% (249) | enoyl-CoA hydratase/isomerase family protein |
| M. thermoresistible (build 8) | TH_3154 | - | 3e-78 | 60.58% (241) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_2995 | echA8_6 | 2e-84 | 64.61% (243) | enoyl-CoA hydratase, EchA8_6 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2855|M.bovis_AF2122/97 ----MTDDILLIDTDERVRTLTLNRPQSRNALSAALRDRFFAALADAEAD
Rv2831|M.tuberculosis_H37Rv ----MTDDILLIDTDERVRTLTLNRPQSRNALSAALRDRFFAALADAEAD
MLBr_02402|M.leprae_Br4923 ----MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKELDID
Mflv_3325|M.gilvum_PYR-GCK -------MTLQISDENRVRTLVLNRPDALNAFNQELYLATATALRDAADD
TH_3154|M.thermoresistible__bu ---------VQISDVNKVRTLTLDRPEALNAFNEALYDATTVALRDADAD
MMAR_2759|M.marinum_M -------MTLQIDDDNRVRTLTLNRPEALNAFNEALYDATAQALLDAADD
MUL_2995|M.ulcerans_Agy99 -------MTLQIDDDNRVRTLTLNRPEALNAFNEALYDATAQALWDAADD
MAV_2835|M.avium_104 -------MTLQIDDDKRVRTLTLNRPEALNAFNEALYDATAEALLAAAED
MSMEG_0340|M.smegmatis_MC2_155 --------MLEITDQNRVRTIALARHDALNAFDEALYDATAIALQDAAED
Mvan_0340|M.vanbaalenii_PYR-1 --------MLIHSTDKRVRTVTFDRAEAMNAFNEALYHATADALLDAASD
MAB_0905|M.abscessus_ATCC_1997 MTQTAPAAVAYSVNHAGVAAIVLDRPEASNALDRTMKTELLQALLAAGGD
* :.: * :: **:. : * *
Mb2855|M.bovis_AF2122/97 DDIDVVILTGADPVFCAGLDLKELAGQTALP---DISP----------RW
Rv2831|M.tuberculosis_H37Rv DDIDVVILTGADPVFCAGLDLKELAGQTALP---DISP----------RW
MLBr_02402|M.leprae_Br4923 PDVGAILITGSPKVFAAGADIKEMASLTFTD---AFDAD---FFSAWGKL
Mflv_3325|M.gilvum_PYR-GCK PEVAVVLLTGAGRAFSAGNDLKEMQAGITDG---SLTADGSHFTTMIDAL
TH_3154|M.thermoresistible__bu PDVSVVLLTGAGRAFSAGNDLVEMQARITDP---DFTPGEHGFPGLMKAL
MMAR_2759|M.marinum_M PQVAVVLLTGSGRGFSAGTDLAEMQARITDP---NFSEGKFGFRGLIKAL
MUL_2995|M.ulcerans_Agy99 PQVAVVVLTGSGRGFSAGTDLAEMQARINDR---NFSEGKFGFRGLIEAL
MAV_2835|M.avium_104 PEVAVVLLTGAGRGFSAGTDLAEMQARITDP---DFTPGKHGFIGLINAL
MSMEG_0340|M.smegmatis_MC2_155 GDVAVVILTGSGRAFCAGTDLKELHARATKN---GFVPGKYGFNGLMAVL
Mvan_0340|M.vanbaalenii_PYR-1 DDVAVVVLTGQGRAFCAGTDLQEMLDRDPSI---PFTEGAHGFRRLIDNL
MAB_0905|M.abscessus_ATCC_1997 PAVRAVVMSAAGKNFCVGQDLAEHVEALRDDPAHAMDTVREHYNPVLEAL
: .::::. *..* *: * :
Mb2855|M.bovis_AF2122/97 PAMTKPVIGAINGAAVTGGLELALYCDILIASEHARFADTHARVGLLPTW
Rv2831|M.tuberculosis_H37Rv PAMTKPVIGAINGAAVTGGLELALYCDILIASEHARFADTHARVGLLPTW
MLBr_02402|M.leprae_Br4923 AAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPGM
Mflv_3325|M.gilvum_PYR-GCK IDLPKPLICAVNGVGLGIGTTILGYADLVFMSSTARLKCPFTSLGVAPEA
TH_3154|M.thermoresistible__bu LDLRKPLICAVNGVAVGIGTTILGYADLVFMADTARLKCPFTSLGVAPEA
MMAR_2759|M.marinum_M AGFPKPLICAVNGLGVGIGATILGYADLAFMSSTARLKCPFTSLGVAPEA
MUL_2995|M.ulcerans_Agy99 AGFPKPLICAVNGLGVGIGATILGYADLAFMSSTARLKCPFTSLGVAPEA
MAV_2835|M.avium_104 SAFPKPLICAVNGVGVGIGATILGYADLAFMSSTARLKCPFTSLGVAPEA
MSMEG_0340|M.smegmatis_MC2_155 AEFPKPLICAVNGVGLGIGTTILGFADLAFMSTSARLKCPFTSLALAPEA
Mvan_0340|M.vanbaalenii_PYR-1 IDFPKPLVCAVNGIAVGLGTTLLGYADLVFMSTSARLKCPFTSLGIAPEA
MAB_0905|M.abscessus_ATCC_1997 DAIKVPVVVAINGACVGAGLGLALGADIRIAGQRAKFGTAFTGIGLAADS
. *:: *: * : * : .*: : . *:: . :.: .
Mb2855|M.bovis_AF2122/97 GLSVRLPQKVGIGLARRMSLTGDYLSATDALRAGLVTEVVAHDQLLPTAR
Rv2831|M.tuberculosis_H37Rv GLSVRLPQKVGIGLARRMSLTGDYLSATDALRAGLVTEVVAHDQLLPTAR
MLBr_02402|M.leprae_Br4923 GGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAK
Mflv_3325|M.gilvum_PYR-GCK ASSYLLPQLIGRQNAAWLLLSSEWVDADEAHRMGIAWKVCEPDDLLPEAR
TH_3154|M.thermoresistible__bu GSSYLLPQLMGRQNAAWLLMSSEWVDAEEAQRMGIAWRVCPVDELLAEAR
MMAR_2759|M.marinum_M ASSYLLPQLVGRQNAAWLLMSSEWIDAEEALRMGLVWRICSPEELLPEAR
MUL_2995|M.ulcerans_Agy99 ASSYLLPQLVGRQNAAWLLMSSEWIDAEEALRMGLVWRICSPEELLPEAR
MAV_2835|M.avium_104 ASSYLLPQLVGRQNAAWLLMSSEWVDADEALRMGLVWRVCAPDELLPQAR
MSMEG_0340|M.smegmatis_MC2_155 ASSYLLPALLGRQNAAWVLMSSEWIDAQQALEMGLVWRLCEPDQLDDEVR
Mvan_0340|M.vanbaalenii_PYR-1 ASTYLLPELIGRQNAAWILMSSEWISAEEALAMGLAWKVCEPAELMPTAF
MAB_0905|M.abscessus_ATCC_1997 ALSASLPRLIGASRATAMFLLGDTIDAPTAHTWGLVHEVVDEGSPADVAN
. : *. :* * : : . :.* * *:. .: . .
Mb2855|M.bovis_AF2122/97 RVAASIVGNNQNAVRALLASYHRIDESQTAAGLWLEACAAKQFCTSGDTI
Rv2831|M.tuberculosis_H37Rv RVAASIVGNNQNAVRALLASYHRIDESQTAAGLWLEACAAKQFRTSGDTI
MLBr_02402|M.leprae_Br4923 AVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVTDDQS
Mflv_3325|M.gilvum_PYR-GCK RHAEILAARSIPSLIAVKKTMVAPHRAEIAAATARENAHFQELLGGVANA
TH_3154|M.thermoresistible__bu RHAELLASRPVASLMAVKHTMVEPIRADVEAAIAREYDQFAELLGGAANA
MMAR_2759|M.marinum_M RHAEILAAKPISSLMAVKHTMVEPNRAQIAAASARENAHFAELMGAQANA
MUL_2995|M.ulcerans_Agy99 RHAEILAAKPISSLMAVKHTMVEPNRAQIAAASARENAHFAELMGAQANA
MAV_2835|M.avium_104 HHAEILASRPISSLMAVKHTMMEPVRPQIAAATARENAHFAELMGAQANA
MSMEG_0340|M.smegmatis_MC2_155 RHAELLASHPISSLIAVKRTLTAPHVEAVRAALAREDALLEELLGAPPNM
Mvan_0340|M.vanbaalenii_PYR-1 DYAERLAAQPLESLVAVKQAMGAPHAADIRAALALENALLDRLVGGPANT
MAB_0905|M.abscessus_ATCC_1997 SVAGRLAGGPTAAFSEVKELLRRNAVAPLGDVLEREASAQQRLGASRDHS
* : : *
Mb2855|M.bovis_AF2122/97 AANREAVLQRGRAQVR-
Rv2831|M.tuberculosis_H37Rv AANREAVLQRGRAQVR-
MLBr_02402|M.leprae_Br4923 EGMAAFIEKRAPQFTHR
Mflv_3325|M.gilvum_PYR-GCK AALAEFTQKG-------
TH_3154|M.thermoresistible__bu DALAEFTGRKK------
MMAR_2759|M.marinum_M AALADFTDRRRP-----
MUL_2995|M.ulcerans_Agy99 AALADFTDRRRP-----
MAV_2835|M.avium_104 AALADFNKR--------
MSMEG_0340|M.smegmatis_MC2_155 AALAQFVGKRD------
Mvan_0340|M.vanbaalenii_PYR-1 QALNGFAAARASRER--
MAB_0905|M.abscessus_ATCC_1997 AAVEAFLAKDKPVFVGR
.