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TLQIDDDKRVRTLTLNRPEALNAFNEALYDATAEALLAAAEDPEVAVVLLTGAGRGFSAGTDLAEMQARI TDPDFTPGKHGFIGLINALSAFPKPLICAVNGVGVGIGATILGYADLAFMSSTARLKCPFTSLGVAPEAA SSYLLPQLVGRQNAAWLLMSSEWVDADEALRMGLVWRVCAPDELLPQARHHAEILASRPISSLMAVKHTM MEPVRPQIAAATARENAHFAELMGAQANAAALADFNKR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2835 | - | - | 100% (249) | enoyl-CoA hydratase/isomerase family protein |
| M. avium 104 | MAV_1590 | - | 1e-25 | 34.39% (221) | enoyl-CoA hydratase |
| M. avium 104 | MAV_1195 | - | 2e-24 | 29.39% (245) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2855 | echA16 | 2e-28 | 37.85% (214) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_3325 | - | 1e-102 | 75.10% (249) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv2831 | echA16 | 2e-28 | 37.85% (214) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 3e-27 | 31.43% (245) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0905 | - | 3e-23 | 30.13% (239) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_2759 | echA8_6 | 1e-124 | 87.95% (249) | enoyl-CoA hydratase, EchA8_6 |
| M. smegmatis MC2 155 | MSMEG_3567 | - | 1e-102 | 72.29% (249) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_3154 | - | 1e-103 | 75.30% (247) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_2995 | echA8_6 | 1e-121 | 86.35% (249) | enoyl-CoA hydratase, EchA8_6 |
| M. vanbaalenii PYR-1 | Mvan_3046 | - | 1e-101 | 75.61% (246) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2855|M.bovis_AF2122/97 ----MTDDILLIDTDERVRTLTLNRPQSRNALSAALRDRFFAALADAEAD
Rv2831|M.tuberculosis_H37Rv ----MTDDILLIDTDERVRTLTLNRPQSRNALSAALRDRFFAALADAEAD
MLBr_02402|M.leprae_Br4923 ----MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKELDID
MMAR_2759|M.marinum_M -------MTLQIDDDNRVRTLTLNRPEALNAFNEALYDATAQALLDAADD
MUL_2995|M.ulcerans_Agy99 -------MTLQIDDDNRVRTLTLNRPEALNAFNEALYDATAQALWDAADD
MAV_2835|M.avium_104 -------MTLQIDDDKRVRTLTLNRPEALNAFNEALYDATAEALLAAAED
Mflv_3325|M.gilvum_PYR-GCK -------MTLQISDENRVRTLVLNRPDALNAFNQELYLATATALRDAADD
Mvan_3046|M.vanbaalenii_PYR-1 -------MTLQITDENRVRTLVLNRPEALNAFNQELYLATATALREAADD
TH_3154|M.thermoresistible__bu ---------VQISDVNKVRTLTLDRPEALNAFNEALYDATTVALRDADAD
MSMEG_3567|M.smegmatis_MC2_155 -------MNLQIDDSNRVRTLTLNRPDALNAFNEALYDEVTDALLAAGGD
MAB_0905|M.abscessus_ATCC_1997 MTQTAPAAVAYSVNHAGVAAIVLDRPEASNALDRTMKTELLQALLAAGGD
* :.*:**:: **:. : * *
Mb2855|M.bovis_AF2122/97 DDIDVVILTGADPVFCAGLDLKELAGQTALP---DISP----------RW
Rv2831|M.tuberculosis_H37Rv DDIDVVILTGADPVFCAGLDLKELAGQTALP---DISP----------RW
MLBr_02402|M.leprae_Br4923 PDVGAILITGSPKVFAAGADIKEMASLTFTD---AFDAD---FFSAWGKL
MMAR_2759|M.marinum_M PQVAVVLLTGSGRGFSAGTDLAEMQARITDP---NFSEGKFGFRGLIKAL
MUL_2995|M.ulcerans_Agy99 PQVAVVVLTGSGRGFSAGTDLAEMQARINDR---NFSEGKFGFRGLIEAL
MAV_2835|M.avium_104 PEVAVVLLTGAGRGFSAGTDLAEMQARITDP---DFTPGKHGFIGLINAL
Mflv_3325|M.gilvum_PYR-GCK PEVAVVLLTGAGRAFSAGNDLKEMQAGITDG---SLTADGSHFTTMIDAL
Mvan_3046|M.vanbaalenii_PYR-1 PEVAVVLLTGAGRAFSAGNDLKEMQAGIADG---SLTSEGSHFTTMIDAL
TH_3154|M.thermoresistible__bu PDVSVVLLTGAGRAFSAGNDLVEMQARITDP---DFTPGEHGFPGLMKAL
MSMEG_3567|M.smegmatis_MC2_155 PEVSVVLLTGAGRAFSSGNDLVEMQTRIANP---DFTPGEHGFYGMIEAL
MAB_0905|M.abscessus_ATCC_1997 PAVRAVVMSAAGKNFCVGQDLAEHVEALRDDPAHAMDTVREHYNPVLEAL
: .::::.: *. * *: * :
Mb2855|M.bovis_AF2122/97 PAMTKPVIGAINGAAVTGGLELALYCDILIASEHARFADTHARVGLLPTW
Rv2831|M.tuberculosis_H37Rv PAMTKPVIGAINGAAVTGGLELALYCDILIASEHARFADTHARVGLLPTW
MLBr_02402|M.leprae_Br4923 AAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPGM
MMAR_2759|M.marinum_M AGFPKPLICAVNGLGVGIGATILGYADLAFMSSTARLKCPFTSLGVAPEA
MUL_2995|M.ulcerans_Agy99 AGFPKPLICAVNGLGVGIGATILGYADLAFMSSTARLKCPFTSLGVAPEA
MAV_2835|M.avium_104 SAFPKPLICAVNGVGVGIGATILGYADLAFMSSTARLKCPFTSLGVAPEA
Mflv_3325|M.gilvum_PYR-GCK IDLPKPLICAVNGVGLGIGTTILGYADLVFMSSTARLKCPFTSLGVAPEA
Mvan_3046|M.vanbaalenii_PYR-1 TDLPKPLICAVNGVGLGIGTTILGYADLVFMSATARLKCPFTSLGVAPEA
TH_3154|M.thermoresistible__bu LDLRKPLICAVNGVAVGIGTTILGYADLVFMADTARLKCPFTSLGVAPEA
MSMEG_3567|M.smegmatis_MC2_155 ADFPKPFLCAVNGVGVGIGATILGFADLVFMADTARLKCPFTSLGVAPEA
MAB_0905|M.abscessus_ATCC_1997 DAIKVPVVVAINGACVGAGLGLALGADIRIAGQRAKFGTAFTGIGLAADS
. *.: *: * : * : .*: : . *:: . :*: .
Mb2855|M.bovis_AF2122/97 GLSVRLPQKVGIGLARRMSLTGDYLSATDALRAGLVTEVVAHDQLLPTAR
Rv2831|M.tuberculosis_H37Rv GLSVRLPQKVGIGLARRMSLTGDYLSATDALRAGLVTEVVAHDQLLPTAR
MLBr_02402|M.leprae_Br4923 GGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAK
MMAR_2759|M.marinum_M ASSYLLPQLVGRQNAAWLLMSSEWIDAEEALRMGLVWRICSPEELLPEAR
MUL_2995|M.ulcerans_Agy99 ASSYLLPQLVGRQNAAWLLMSSEWIDAEEALRMGLVWRICSPEELLPEAR
MAV_2835|M.avium_104 ASSYLLPQLVGRQNAAWLLMSSEWVDADEALRMGLVWRVCAPDELLPQAR
Mflv_3325|M.gilvum_PYR-GCK ASSYLLPQLIGRQNAAWLLLSSEWVDADEAHRMGIAWKVCEPDDLLPEAR
Mvan_3046|M.vanbaalenii_PYR-1 ASSYLLPQLIGRQNAAWLLLSSEWVDAAEAERMGLAWKVCEPDDLLPEAR
TH_3154|M.thermoresistible__bu GSSYLLPQLMGRQNAAWLLMSSEWVDAEEAQRMGIAWRVCPVDELLAEAR
MSMEG_3567|M.smegmatis_MC2_155 ASSYLMPRLIGRQNAAWLLMSSEWISAAEAKEMGLVFKVCTPGDLLTEAR
MAB_0905|M.abscessus_ATCC_1997 ALSASLPRLIGASRATAMFLLGDTIDAPTAHTWGLVHEVVDEGSPADVAN
. * :.: :* * : : . :.* * *:. .: . *.
Mb2855|M.bovis_AF2122/97 RVAASIVGNNQNAVRALLASYHRIDESQTAAGLWLEACAAKQFCTSGDTI
Rv2831|M.tuberculosis_H37Rv RVAASIVGNNQNAVRALLASYHRIDESQTAAGLWLEACAAKQFRTSGDTI
MLBr_02402|M.leprae_Br4923 AVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVTDDQS
MMAR_2759|M.marinum_M RHAEILAAKPISSLMAVKHTMVEPNRAQIAAASARENAHFAELMGAQANA
MUL_2995|M.ulcerans_Agy99 RHAEILAAKPISSLMAVKHTMVEPNRAQIAAASARENAHFAELMGAQANA
MAV_2835|M.avium_104 HHAEILASRPISSLMAVKHTMMEPVRPQIAAATARENAHFAELMGAQANA
Mflv_3325|M.gilvum_PYR-GCK RHAEILAARSIPSLIAVKKTMVAPHRAEIAAATARENAHFQELLGGVANA
Mvan_3046|M.vanbaalenii_PYR-1 RHAEILASRSIPSLIAVKKTIVEPYRAEIAAATQRENAHFQELLGGVANA
TH_3154|M.thermoresistible__bu RHAELLASRPVASLMAVKHTMVEPIRADVEAAIAREYDQFAELLGGAANA
MSMEG_3567|M.smegmatis_MC2_155 RHAEILAAKPVTSLQAVKETMVAPVREAVAAATRRESELFVELVGAAANA
MAB_0905|M.abscessus_ATCC_1997 SVAGRLAGGPTAAFSEVKELLRRNAVAPLGDVLEREASAQQRLGASRDHS
* : : *
Mb2855|M.bovis_AF2122/97 AANREAVLQRGRAQVR-
Rv2831|M.tuberculosis_H37Rv AANREAVLQRGRAQVR-
MLBr_02402|M.leprae_Br4923 EGMAAFIEKRAPQFTHR
MMAR_2759|M.marinum_M AALADFTDRRRP-----
MUL_2995|M.ulcerans_Agy99 AALADFTDRRRP-----
MAV_2835|M.avium_104 AALADFNKR--------
Mflv_3325|M.gilvum_PYR-GCK AALAEFTQKG-------
Mvan_3046|M.vanbaalenii_PYR-1 AALAEFTGQRKS-----
TH_3154|M.thermoresistible__bu DALAEFTGRKK------
MSMEG_3567|M.smegmatis_MC2_155 EALAAFTGRKGAAGS--
MAB_0905|M.abscessus_ATCC_1997 AAVEAFLAKDKPVFVGR
. :