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MLEITDQNRVRTIALARHDALNAFDEALYDATAIALQDAAEDGDVAVVILTGSGRAFCAGTDLKELHARA TKNGFVPGKYGFNGLMAVLAEFPKPLICAVNGVGLGIGTTILGFADLAFMSTSARLKCPFTSLALAPEAA SSYLLPALLGRQNAAWVLMSSEWIDAQQALEMGLVWRLCEPDQLDDEVRRHAELLASHPISSLIAVKRTL TAPHVEAVRAALAREDALLEELLGAPPNMAALAQFVGKRD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0340 | - | - | 100% (250) | enoyl-CoA hydratase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_3567 | - | 7e-83 | 61.29% (248) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_4299 | - | 1e-22 | 29.46% (241) | enoyl-CoA hydratase/isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1099c | echA8 | 1e-19 | 26.56% (241) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_3325 | - | 1e-85 | 63.16% (247) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1070c | echA8 | 1e-19 | 26.56% (241) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 1e-18 | 26.56% (241) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_3281 | - | 6e-20 | 25.10% (247) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_2759 | echA8_6 | 3e-92 | 67.74% (248) | enoyl-CoA hydratase, EchA8_6 |
| M. avium 104 | MAV_2835 | - | 8e-90 | 67.62% (244) | enoyl-CoA hydratase/isomerase family protein |
| M. thermoresistible (build 8) | TH_3154 | - | 2e-85 | 62.10% (248) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_2995 | echA8_6 | 3e-92 | 67.34% (248) | enoyl-CoA hydratase, EchA8_6 |
| M. vanbaalenii PYR-1 | Mvan_3046 | - | 5e-84 | 62.10% (248) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1099c|M.bovis_AF2122/97 MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIG
Rv1070c|M.tuberculosis_H37Rv MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIG
MLBr_02402|M.leprae_Br4923 MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKELDIDPDVG
Mflv_3325|M.gilvum_PYR-GCK ---MTLQISDENRVRTLVLNRPDALNAFNQELYLATATALRDAADDPEVA
Mvan_3046|M.vanbaalenii_PYR-1 ---MTLQITDENRVRTLVLNRPEALNAFNQELYLATATALREAADDPEVA
TH_3154|M.thermoresistible__bu -----VQISDVNKVRTLTLDRPEALNAFNEALYDATTVALRDADADPDVS
MMAR_2759|M.marinum_M ---MTLQIDDDNRVRTLTLNRPEALNAFNEALYDATAQALLDAADDPQVA
MUL_2995|M.ulcerans_Agy99 ---MTLQIDDDNRVRTLTLNRPEALNAFNEALYDATAQALWDAADDPQVA
MAV_2835|M.avium_104 ---MTLQIDDDKRVRTLTLNRPEALNAFNEALYDATAEALLAAAEDPEVA
MSMEG_0340|M.smegmatis_MC2_155 ----MLEITDQNRVRTIALARHDALNAFDEALYDATAIALQDAAEDGDVA
MAB_3281|M.abscessus_ATCC_1997 --MASDYIAVHNGVLHITIATAAAGTSLDFTGVDAAVQVLRDLP--AEVG
: : * :.: * .::: . . ::.
Mb1099c|M.bovis_AF2122/97 AIIITGSAKAFAAGADIKEMADLTFADAFTAD----FFATWGKLAAVRTP
Rv1070c|M.tuberculosis_H37Rv AIIITGSAKAFAAGADIKEMADLTFADAFTAD----FFATWGKLAAVRTP
MLBr_02402|M.leprae_Br4923 AILITGSPKVFAAGADIKEMASLTFTDAFDAD----FFSAWGKLAAVRTP
Mflv_3325|M.gilvum_PYR-GCK VVLLTGAGRAFSAGNDLKEMQAGITDGSLTADGSH-FTTMIDALIDLPKP
Mvan_3046|M.vanbaalenii_PYR-1 VVLLTGAGRAFSAGNDLKEMQAGIADGSLTSEGSH-FTTMIDALTDLPKP
TH_3154|M.thermoresistible__bu VVLLTGAGRAFSAGNDLVEMQARITDPDFTPGEHG-FPGLMKALLDLRKP
MMAR_2759|M.marinum_M VVLLTGSGRGFSAGTDLAEMQARITDPNFSEGKFG-FRGLIKALAGFPKP
MUL_2995|M.ulcerans_Agy99 VVVLTGSGRGFSAGTDLAEMQARINDRNFSEGKFG-FRGLIEALAGFPKP
MAV_2835|M.avium_104 VVLLTGAGRGFSAGTDLAEMQARITDPDFTPGKHG-FIGLINALSAFPKP
MSMEG_0340|M.smegmatis_MC2_155 VVILTGSGRAFCAGTDLKELHARATKNGFVPGKYG-FNGLMAVLAEFPKP
MAB_3281|M.abscessus_ATCC_1997 AILLTSSGPNFCAGGNVRDFASAEDRSAKLHDLAGRLHAFVRAVDAADRP
.:::*.: *.** :: :: : : *
Mb1099c|M.bovis_AF2122/97 TIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPGMGGSQRL
Rv1070c|M.tuberculosis_H37Rv TIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPGMGGSQRL
MLBr_02402|M.leprae_Br4923 MIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPGMGGSQRL
Mflv_3325|M.gilvum_PYR-GCK LICAVNGVGLGIGTTILGYADLVFMSSTARLKCPFTSLGVAPEAASSYLL
Mvan_3046|M.vanbaalenii_PYR-1 LICAVNGVGLGIGTTILGYADLVFMSATARLKCPFTSLGVAPEAASSYLL
TH_3154|M.thermoresistible__bu LICAVNGVAVGIGTTILGYADLVFMADTARLKCPFTSLGVAPEAGSSYLL
MMAR_2759|M.marinum_M LICAVNGLGVGIGATILGYADLAFMSSTARLKCPFTSLGVAPEAASSYLL
MUL_2995|M.ulcerans_Agy99 LICAVNGLGVGIGATILGYADLAFMSSTARLKCPFTSLGVAPEAASSYLL
MAV_2835|M.avium_104 LICAVNGVGVGIGATILGYADLAFMSSTARLKCPFTSLGVAPEAASSYLL
MSMEG_0340|M.smegmatis_MC2_155 LICAVNGVGLGIGTTILGFADLAFMSTSARLKCPFTSLALAPEAASSYLL
MAB_3281|M.abscessus_ATCC_1997 VVASVHGWAAGGGLSLVLLADIAIGGQSTKLRAAYPGIGYSSDGGMSWAL
:.:* * . * * : .*: : . :::: . :. . . * *
Mb1099c|M.bovis_AF2122/97 TRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARATATTI
Rv1070c|M.tuberculosis_H37Rv TRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARATATTI
MLBr_02402|M.leprae_Br4923 TRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAKAVATTI
Mflv_3325|M.gilvum_PYR-GCK PQLIGRQNAAWLLLSSEWVDADEAHRMGIAWKVCEPDDLLPEARRHAEIL
Mvan_3046|M.vanbaalenii_PYR-1 PQLIGRQNAAWLLLSSEWVDAAEAERMGLAWKVCEPDDLLPEARRHAEIL
TH_3154|M.thermoresistible__bu PQLMGRQNAAWLLMSSEWVDAEEAQRMGIAWRVCPVDELLAEARRHAELL
MMAR_2759|M.marinum_M PQLVGRQNAAWLLMSSEWIDAEEALRMGLVWRICSPEELLPEARRHAEIL
MUL_2995|M.ulcerans_Agy99 PQLVGRQNAAWLLMSSEWIDAEEALRMGLVWRICSPEELLPEARRHAEIL
MAV_2835|M.avium_104 PQLVGRQNAAWLLMSSEWVDADEALRMGLVWRVCAPDELLPQARHHAEIL
MSMEG_0340|M.smegmatis_MC2_155 PALLGRQNAAWVLMSSEWIDAQQALEMGLVWRLCEPDQLDDEVRRHAELL
MAB_3281|M.abscessus_ATCC_1997 PRVVGKARAADILLTDRVVEASEALSIGLLSRVVADDEVQATAVATAEQL
. :*: .* ::::.. ::* :* *: :: ::: . * :
Mb1099c|M.bovis_AF2122/97 SQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSEGMAAF
Rv1070c|M.tuberculosis_H37Rv SQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSEGMAAF
MLBr_02402|M.leprae_Br4923 SQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVTDDQSEGMAAF
Mflv_3325|M.gilvum_PYR-GCK AARSIPSLIAVKKTMVAPHRAEIAAATARENAHFQELLGGVANAAALAEF
Mvan_3046|M.vanbaalenii_PYR-1 ASRSIPSLIAVKKTIVEPYRAEIAAATQRENAHFQELLGGVANAAALAEF
TH_3154|M.thermoresistible__bu ASRPVASLMAVKHTMVEPIRADVEAAIAREYDQFAELLGGAANADALAEF
MMAR_2759|M.marinum_M AAKPISSLMAVKHTMVEPNRAQIAAASARENAHFAELMGAQANAAALADF
MUL_2995|M.ulcerans_Agy99 AAKPISSLMAVKHTMVEPNRAQIAAASARENAHFAELMGAQANAAALADF
MAV_2835|M.avium_104 ASRPISSLMAVKHTMMEPVRPQIAAATARENAHFAELMGAQANAAALADF
MSMEG_0340|M.smegmatis_MC2_155 ASHPISSLIAVKRTLTAPHVEAVRAALAREDALLEELLGAPPNMAALAQF
MAB_3281|M.abscessus_ATCC_1997 AAGPREAQNRIRRLLRLSATNTLDAQLDLEQTSIAEASVSPTGIEGVDAF
: . : :. : . : * : . .: *
Mb1099c|M.bovis_AF2122/97 IEKRAPQFTHR
Rv1070c|M.tuberculosis_H37Rv IEKRAPQFTHR
MLBr_02402|M.leprae_Br4923 IEKRAPQFTHR
Mflv_3325|M.gilvum_PYR-GCK TQKG-------
Mvan_3046|M.vanbaalenii_PYR-1 TGQRKS-----
TH_3154|M.thermoresistible__bu TGRKK------
MMAR_2759|M.marinum_M TDRRRP-----
MUL_2995|M.ulcerans_Agy99 TDRRRP-----
MAV_2835|M.avium_104 NKR--------
MSMEG_0340|M.smegmatis_MC2_155 VGKRD------
MAB_3281|M.abscessus_ATCC_1997 VGKRKPVWP--
: