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SILPVPVVADTVARVFAAAVNPAPKAAVRFADIPGRTAQVTIPTRHGPVTATIYHPPSEVQSPPVYANVH GGGFVVGHPEQDDPWCRYLAANAGVVVVNPDYALAPRRRFPAAPQQIYDIVCWAADEARDWDGTRLCVGG QSAGGNLSAAAARLALENRTPIISLQVLHYAPLDLVTPTRDKPSAFGARAVLKPWMGEVFDTAYIPDPAQ RSDRLASPAWGANAEDIVGIAPAVVVTAEHDRLRNEGHRYAKKLDAAGSLVEYHEVAGVDHGYNIMGGAL GATEQVYSRIAGHVARATGSA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0324 | - | - | 100% (302) | alpha/beta hydrolase domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2162 | - | 3e-31 | 35.09% (265) | alpha/beta hydrolase domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2888 | - | 1e-30 | 34.20% (269) | alpha/beta hydrolase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2994c | lipN | 3e-31 | 33.91% (289) | lipase/esterase LipN |
| M. gilvum PYR-GCK | Mflv_4203 | - | 1e-31 | 33.22% (304) | alpha/beta hydrolase domain-containing protein |
| M. tuberculosis H37Rv | Rv2970c | lipN | 3e-31 | 33.91% (289) | lipase/esterase LipN |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3270c | - | 6e-31 | 33.33% (276) | lipase/esterase LipN |
| M. marinum M | MMAR_1746 | lipN | 7e-30 | 32.45% (265) | lipase/esterase LipN |
| M. avium 104 | MAV_3814 | - | 7e-32 | 33.08% (266) | alpha/beta hydrolase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_6852 | - | 1e-124 | 72.58% (299) | putative carboxylesterase/lipase |
| M. thermoresistible (build 8) | TH_2562 | - | 4e-23 | 32.57% (261) | PUTATIVE Alpha/beta hydrolase fold-3 domain protein |
| M. ulcerans Agy99 | MUL_1989 | lipN | 3e-30 | 32.45% (265) | lipase/esterase LipN |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1746|M.marinum_M MTNSLPGETD---LHPETVHATMSWLSRVQNTVTVVGAKVIPWVPDVAKR
MUL_1989|M.ulcerans_Agy99 MTNSLPGETD---LHPETVHATMSWLSRVQNTVTVVGAKVIPWVPDVAKR
MAV_3814|M.avium_104 MTKPLTDTAP---VDPGVQRGSMPLTNRIQGAVTSVGVKVIPWIPTAVRR
Mb2994c|M.bovis_AF2122/97 MTKSLPGVAD---LRLGANHPRM-WTRRVQGTVVNVGVKVLPWIPTPAKR
Rv2970c|M.tuberculosis_H37Rv MTKSLPGVAD---LRLGANHPRM-WTRRVQGTVVNVGVKVLPWIPTPAKR
MAB_3270c|M.abscessus_ATCC_199 -------------------------MSPFRDFALRASTAATPHIPTPVRR
Mflv_4203|M.gilvum_PYR-GCK MPASRATESHNNWTTPKGSPHAGGAVEKLTNTLAGVTLRALPRIPDPVKR
Mvan_0324|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6852|M.smegmatis_MC2_155 --------------------------------------------------
TH_2562|M.thermoresistible__bu --------------------------------------------------
MMAR_1746|M.marinum_M LITRGRSVIIDGNTLDPALQLMLSGMRVVGLDGLVIDDDLAASRAHMREA
MUL_1989|M.ulcerans_Agy99 LITRGRSVIIDGNTLDPALQLMLSGMRVVGLDGLVIDDDLAASRAHMREA
MAV_3814|M.avium_104 GLVRGRSVIIDGNTLDPTLQLMLSGLRAVGIDGLVVDDDPELSRAQMHES
Mb2994c|M.bovis_AF2122/97 ILSAGRSVIIDGNTLDPTLQLMLSTSRIFGVDGLAVDDDIVASRAHMRAI
Rv2970c|M.tuberculosis_H37Rv ILSAGRSVIIDGNTLDPTLQLMLSTSRIFGVDGLAVDDDIVASRAHMRAI
MAB_3270c|M.abscessus_ATCC_199 AMA-GRQVIIDGNILDPTTQLLLRGMELMGEGEISRGEDVAENRANMRRQ
Mflv_4203|M.gilvum_PYR-GCK LLLGRRTITLDGNTLDTTLHLMLAGQRLMGIEGLVADDDVTVARAQLEVL
Mvan_0324|M.vanbaalenii_PYR-1 -------------------------MSILPVPVVADTVARVFAAAVNPAP
MSMEG_6852|M.smegmatis_MC2_155 -------------------------MALLSNRVVADALARTFAATVNPAP
TH_2562|M.thermoresistible__bu -----VNPPEAGQRLAPELRHLWGTRTDLTADLLPTVRAVLDDRRRATAA
. :
MMAR_1746|M.marinum_M MLGFPGPQIHVDVEELTLPGPAGDISARHYRPPG-DAAAPLLVFYHGGGW
MUL_1989|M.ulcerans_Agy99 MLGFPGPQIHVDVEELTLPGPAGDISARHYRPPG-DAAAPLLVFYHGGGW
MAV_3814|M.avium_104 TVGFPGPQIHVDVAELALPGPAGDIPARHYRPAGGETQAPLLVFYHGGGW
Mb2994c|M.bovis_AF2122/97 CEAMPGPQIHVDVTDLSIPGPAGEIPARHYRPSG-GGATPLLVFYHGGGW
Rv2970c|M.tuberculosis_H37Rv CEAMPGPQIHVDVTDLSIPGPAGEIPARHYRPSG-GGATPLLVFYHGGGW
MAB_3270c|M.abscessus_ATCC_199 AGLLQFSTPVGQVRNFSIPGPAGPIGVRHYKPVH-DHTGALLVFFHGGGW
Mflv_4203|M.gilvum_PYR-GCK AAAFKQHIPVAAVTNLTVPGAQGPLDARHYRTDE--PDAALLVFFHGGGH
Mvan_0324|M.vanbaalenii_PYR-1 KAAVRFADIPGRTAQVTIPTRHGPVTATIYHPPSEVQSPPVYANVHGGGF
MSMEG_6852|M.smegmatis_MC2_155 KPGVRFSDITCRTSDAAIPTRHGTVFARIYHPPAAGATSAVYVNVHGGGF
TH_2562|M.thermoresistible__bu AVDTGG----VHIDDREIHCGTGPIEIRIYRGRR--GVAPAVLYCHAGAF
: : * : *: . *.*.
MMAR_1746|M.marinum_M ALGDLDTHDAVCRLTCRDAGIHVLAIDYRLSPEDRAPAAIDDAFAAFEWA
MUL_1989|M.ulcerans_Agy99 ALGDLDTHDAVCRLTCRDAGIHVLAIDYRLSPEHRAPAAIDDAFAAFEWA
MAV_3814|M.avium_104 SIGDLDTHDSLCRLTCRDAGIHVLSIDYRLAPEHPAPAAIDDAYAAFTWA
Mb2994c|M.bovis_AF2122/97 TLGDLDTHDALCRLTCRDADIQVLSIDYRLAPEHPAPAAVEDAYAAFVWA
Rv2970c|M.tuberculosis_H37Rv TLGDLDTHDALCRLTCRDADIQVLSIDYRLAPEHPAPAAVEDAYAAFVWA
MAB_3270c|M.abscessus_ATCC_199 VIGDLETHDQPCRQTCRDAGVSVLSVDYRLAPEHKAPAAAQDCLAAYLWA
Mflv_4203|M.gilvum_PYR-GCK VIGSLDSHDDLCREICRAGRIHVLSVDYRLAPEHKAPAGAQDAYSAYLWA
Mvan_0324|M.vanbaalenii_PYR-1 VVGHPEQDDPWCRYLAANAGVVVVNPDYALAPRRRFPAAPQQIYDIVCWA
MSMEG_6852|M.smegmatis_MC2_155 VVGHPEQDDPWCRYLATHAEVVVVNPDYVLAPRHRFPAAPQQIYDVVCWA
TH_2562|M.thermoresistible__bu VLGNLDTDHRQCVELARRAECTVVSVDYRLAPEHPWPAAVDDATAVLSWL
:* : .. * . . *: ** *:*. **. :: *
MMAR_1746|M.marinum_M HAHAA-ELGALPGRVAVGGDSAGGNLAAVVSQLARD----SGGPAPIFQW
MUL_1989|M.ulcerans_Agy99 HAHAA-ELGALPGRVAVGGDSAGGNLAAVVSQLARD----SGGPAPIFQW
MAV_3814|M.avium_104 HEHAG-ELGAIPGRVAVGGDSAGGNLAAVVSQLARD----AGGPAPVLQW
Mb2994c|M.bovis_AF2122/97 HEHASDEFGALPGRVAVGGDSAGGNLSAVVCQLARDKARYEGGPTPVLQW
Rv2970c|M.tuberculosis_H37Rv HEHASDEFGALPGRVAVGGDSAGGNLSAVVCQLARDKARYEGGPTPVLQW
MAB_3270c|M.abscessus_ATCC_199 VEHAG-DLGVAPDRIAVGGDSAGGNLAAVVAQQARD----TGAQLPLLQF
Mflv_4203|M.gilvum_PYR-GCK REHAA-ELGADPERVAVGGDSAGGNLSAVLTQRARD----EGAPLPALQV
Mvan_0324|M.vanbaalenii_PYR-1 ADEAR---DWDGTRLCVGGQSAGGNLSAAAARLALE----NRTPIISLQV
MSMEG_6852|M.smegmatis_MC2_155 AAPDR---DWDGSRICVGGQSAGGNLSAAAARLALR----HGTPRISLQV
TH_2562|M.thermoresistible__bu AGNAT-ALDVDPARLAVAGSSAGGALAAGLAQRSGR----NGLPQLVFQL
. *:.*.*.**** *:* : : :*
MMAR_1746|M.marinum_M LIYPRTDFAGRTRSA-SLFARGFLLTKRDIDWFHSQYLKGSGIEPTDPRV
MUL_1989|M.ulcerans_Agy99 LIYPRTDFAGRTRSA-SLFARGFLLTKRDIDWFHSQYLKGSGIEPTDPRV
MAV_3814|M.avium_104 LIYPRTDFTARTRSL-SLFSRGFLLTKRDIDWFESQYLRNSGLDRTDPRV
Mb2994c|M.bovis_AF2122/97 LLYPRTDFTAQTRSM-GLFGNGFLLTKRDIDWFHTQYLRDSDVDPADPRL
Rv2970c|M.tuberculosis_H37Rv LLYPRTDFTAQTRSM-GLFGNGFLLTKRDIDWFHTQYLRDSDVDPADPRL
MAB_3270c|M.abscessus_ATCC_199 LIYPAVDFTVRRPSR-DLFAEGFFLTKAAMDGFESHYLDGSDVDKADPQV
Mflv_4203|M.gilvum_PYR-GCK LLYPATEVGIQTRSQ-TLFSDGFFLTKRDMDWFMDHFLDGADVADTDPRV
Mvan_0324|M.vanbaalenii_PYR-1 LHYAPLDLVTPTRDKPSAFGARAVLKPWMGEVFDTAYIPDP-AQRSDRLA
MSMEG_6852|M.smegmatis_MC2_155 LHYAPLDLVTPTRDKPSTIGRRAVMKPWMGEVFDTAYIPDP-AQRRDPLA
TH_2562|M.thermoresistible__bu LHQPALDDRVTPSKA--EFCTTPGFDGPACDQMWRHYLAGAAPTAA---A
* . : . : : : : :: ..
MMAR_1746|M.marinum_M SPLR---AESLAGLAPALIAVAGFDPLRDEGENYATALRAAGTPVDLRAM
MUL_1989|M.ulcerans_Agy99 SPLR---AESLAGLAPALIAVAGFDPLRDEGENYATALRAAGTPVDLRAM
MAV_3814|M.avium_104 SPAL---AESLAGLAPALIAVAGFDPLRDEGQSYAEALRAAGTPVDLRYL
Mb2994c|M.bovis_AF2122/97 SPLL---AESLSGLAPALIAVAGFDPLRDEGESYAKALRAAGTAVDLRYL
Rv2970c|M.tuberculosis_H37Rv SPLL---AESLSGLAPALIAVAGFDPLRDEGESYAKALRAAGTAVDLRYL
MAB_3270c|M.abscessus_ATCC_199 SPIL---AADLAGLPPALITTAGFDPLRDEGNEYAAKLRAAGVPVDLRVQ
Mflv_4203|M.gilvum_PYR-GCK SPLR---TDDMSGLPPALVVTAGFDPLRDEGRLYAEALREAGTPVDYREY
Mvan_0324|M.vanbaalenii_PYR-1 SPAWGANAEDIVGIAPAVVVTAEHDRLRNEGHRYAKKLDAAGSLVEYHEV
MSMEG_6852|M.smegmatis_MC2_155 SPAWDQATDDLSGIAPAVVVTAEFDRLRNEARTYAERLRSFGALREYIEV
TH_2562|M.thermoresistible__bu APGR---ADDLTGAPPAFISCSELDPLRDEALDYAARLLRCGVPTELHLF
:* : .: * .**.: : * **:*. ** * * :
MMAR_1746|M.marinum_M GSLTHGFLNLFPLGGGCAAATSELISALRAHLTRV--------
MUL_1989|M.ulcerans_Agy99 GSLTHGFLNLFPLGGGCAAATSELISALRAHLTRV--------
MAV_3814|M.avium_104 GSLTHGFANLFQLGGDSMVATSELISALRAHLSRV--------
Mb2994c|M.bovis_AF2122/97 GSLTHGFLNLFQLGGGSAAGTNELISALRAHLSRV--------
Rv2970c|M.tuberculosis_H37Rv GSLTHGFLNLFQLGGGSAAGTNELISALRAHLSRV--------
MAB_3270c|M.abscessus_ATCC_199 GPLIHGFYNMAGLGGAPSEAMNQLTSALRAHLSR---------
Mflv_4203|M.gilvum_PYR-GCK GTVVHGFANFFPLGGDSATAMADVISAIRAHLTRAG-------
Mvan_0324|M.vanbaalenii_PYR-1 AGVDHGYNIMGGALGATEQVYSRIAGHVARATGSA--------
MSMEG_6852|M.smegmatis_MC2_155 PDVDHGYNIMTNATDVTRGVYDRVAHHVRRATDDGGQGRS---
TH_2562|M.thermoresistible__bu PGTCHGFDSLLPEWELSRQLFALQAAAVRRAFTTAEYPAGQVN
**: : :