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MHQVDPNLTRRKGRLAALAIAAMASASLVTVAVPATANADPEPAPPVPTTAASPPSTAAAPPAPATPVAP PPPAAANTPNAQPGDPNAAPPPADPNAPPPPVIAPNAPQPVRIDNPVGGFSFALPAGWVESDAAHFDYGS ALLSKTTGDPPFPGQPPPVANDTRIVLGRLDQKLYASAEATDSKAAARLGSDMGEFYMPYPGTRINQETV SLDANGVSGSASYYEVKFSDPSKPNGQIWTGVIGSPAANAPDAGPPQRWFVVWLGTANNPVDKGAAKALA ESIRPLVAPPPAPAPAPAEPAPAPAPAGEVAPTPTTPTPQRTLPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1860 | apa | - | 100% (325) | ALANINE AND PROLINE RICH SECRETED PROTEIN APA (FIBRONECTIN ATTACHMENT PROTEIN) (Immunogenic protein MPT32) (Antigen MPT-32) (45-kDa glycoprotein) (45/47 kDa antigen) |
| M. tuberculosis H37Rv | Rv3876 | - | 5e-11 | 34.69% (147) | hypothetical protein Rv3876 |
| M. tuberculosis H37Rv | Rv3886c | mycP2 | 3e-10 | 32.11% (190) | alanine and proline rich membrane-anchored mycosin |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1891 | apa | 0.0 | 99.69% (325) | hypothetical protein Mb1891 |
| M. gilvum PYR-GCK | Mflv_3345 | - | 2e-85 | 52.44% (328) | fibronectin-attachment family protein |
| M. leprae Br4923 | MLBr_02055 | modD | 1e-106 | 66.78% (298) | putative cell surface protein (associated with virulence) |
| M. abscessus ATCC 19977 | MAB_2436 | - | 4e-65 | 44.97% (318) | hypothetical protein MAB_2436 |
| M. marinum M | MMAR_2737 | apa | 1e-135 | 70.92% (337) | alanine and proline rich secreted protein Apa |
| M. avium 104 | MAV_2859 | - | 1e-110 | 57.11% (394) | ModD protein |
| M. smegmatis MC2 155 | MSMEG_3618 | - | 1e-90 | 51.12% (358) | alanine and proline-rich secreted protein apa |
| M. thermoresistible (build 8) | TH_1368 | modD | 8e-70 | 56.40% (250) | ALANINE AND PROLINE RICH SECRETED PROTEIN APA (FIBRONECTIN |
| M. ulcerans Agy99 | MUL_3017 | apa | 1e-126 | 66.96% (336) | alanine and proline rich secreted protein Apa |
| M. vanbaalenii PYR-1 | Mvan_3075 | - | 3e-82 | 50.75% (333) | fibronectin-attachment family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3345|M.gilvum_PYR-GCK MTMDQPNVF-----PHRRAGTPTSIRRSVVTGATTAALAAALALPGIANA
Mvan_3075|M.vanbaalenii_PYR-1 --MDQPDMH-----AKRRKGLPTSFRRSALTGAT-AALTAVFTLPAVAYA
MSMEG_3618|M.smegmatis_MC2_155 --MYESDSM-----SHRRSGLSKKLTLAAVTGMT----AVAVALPSVAHA
TH_1368|M.thermoresistible__bu --------------------------------------------------
Rv1860|M.tuberculosis_H37Rv --MHQVDPN-----LTRRKGRLAALAIAAMASAS----LVTVAVPATANA
Mb1891|M.bovis_AF2122/97 --MHQVDPN-----LTRRKGRLAALAIAAMASAS----LVTVAVPATANA
MLBr_02055|M.leprae_Br4923 --MNQVDLD-----STHRKGLWAILAIAVVASAS----AFTMPLPAAANA
MMAR_2737|M.marinum_M --MHEVDPN-----KRRRHGLWTTLALAAVSSAS----VVSIALPATASA
MUL_3017|M.ulcerans_Agy99 --MHEVDPN-----KRRRHGLWTTLALAAVSSAS----VVSIALPATASA
MAV_2859|M.avium_104 --MDQVEAT-----STRRKGLWTTLAITTVSGAS----AVAIALPATSHA
MAB_2436|M.abscessus_ATCC_1997 --MQQPRATSAAKRTHRARVIAATIAVTSLSGAG----AYTLAATPVDQA
Mflv_3345|M.gilvum_PYR-GCK QPAPTPTP-------APPPPAVGAPQA-----PAPDAPAA-----PAPAP
Mvan_3075|M.vanbaalenii_PYR-1 QPAPPPSP-------APPPAVEAPPVP-----PPPVDPNA-----PVPPP
MSMEG_3618|M.smegmatis_MC2_155 DPEPPPPPPGNTFLPAPPPADPNAPAPAPAPAPAPAPAPA-----PALAP
TH_1368|M.thermoresistible__bu ---------------VPPPGQP----------------------------
Rv1860|M.tuberculosis_H37Rv DPEPAPPVPTTAASPPSTAAAPPAPATPVAP-PPPAAANT------PNAQ
Mb1891|M.bovis_AF2122/97 DPEPAPPVPTTAASPPSTAAAPPAPATPVAP-PPPAAANT------PNAQ
MLBr_02055|M.leprae_Br4923 DPAPLP---------PSTATAAPSPAQEIIT-PLPGAPVS------SEAQ
MMAR_2737|M.marinum_M DPAPAP--------APSTTAAP--PADPNAA-PPPADPNA------PPPP
MUL_3017|M.ulcerans_Agy99 DPAPAP--------APSTTAAP--PADPNAA-PPPADP------------
MAV_2859|M.avium_104 DPEVPTPVPPSTATAPPAAPAPNGQPAPNAQ-PAPAAPAPNGQPAPAAPA
MAB_2436|M.abscessus_ATCC_1997 PATVRTANIHLVTTDAPPPPAPPATPAPGQPAPNPETPTT------VTTP
...
Mflv_3345|M.gilvum_PYR-GCK PADPNAPAPAAP----PATPPADPNAPVPPPADPNAPAPAGPEAPAAPAP
Mvan_3075|M.vanbaalenii_PYR-1 PVDPNAPVPPP--------PPVDPNAPVPPPADPNAPVP--------PAP
MSMEG_3618|M.smegmatis_MC2_155 APAPGAPAPAPA----PAPAPADPNAPAPAPADPNAPAPAPAE--EPPAP
TH_1368|M.thermoresistible__bu ----------------------------PAPADPNAPA--------EPAP
Rv1860|M.tuberculosis_H37Rv PGDPNAAP-----------PPADPNAPPPPVIAPNAPQP-----------
Mb1891|M.bovis_AF2122/97 PGDPNAAP-----------PPADPNAPPPPVIAPNAPQP-----------
MLBr_02055|M.leprae_Br4923 PGDPNA-------------PSLDPNAPYPLAVDPNAG-------------
MMAR_2737|M.marinum_M PADPNAPPPPPADPNAPPPPPADPNAPPPPVVDPNAPEP-----------
MUL_3017|M.ulcerans_Agy99 ------------------------NAPPPPVVDPNAPEP-----------
MAV_2859|M.avium_104 PNDPNAAPPPAG-APPNGAPPAPPNGAPPPPVDPNAPPPPPAD------P
MAB_2436|M.abscessus_ATCC_1997 PPAPAP----------------GQPAPPTPPPAPGAPAD-----------
. *.*
Mflv_3345|M.gilvum_PYR-GCK EPGRVDNAAGGFSYVVPAGWKVSDATQLSYGQALLSKLP--PEGSPPDAQ
Mvan_3075|M.vanbaalenii_PYR-1 EPGRIDNAAGGFSYVVPAGWEVSDSTQLSYGQALLTKLP--PEGAPPDAQ
MSMEG_3618|M.smegmatis_MC2_155 EPGRVDNAAGGFSYVVPEGWQVSDATQLSYGQALLTKTV--AEGAE----
TH_1368|M.thermoresistible__bu EP-RENNAAGGFSYVVPGGWQVSDATQLSYGQALLTKIP--PPGSQQ---
Rv1860|M.tuberculosis_H37Rv --VRIDNPVGGFSFALPAGWVESDAAHFDYGSALLSKTTGDPPFPGQPPP
Mb1891|M.bovis_AF2122/97 --VRIDNPVGGFSFALPAGWVESDAAHLDYGSALLSKTTGDPPFPGQPPP
MLBr_02055|M.leprae_Br4923 ---RITNAVGGFSFVLPAGWVESEASHLDYGSVLLSKAIEQPPVLGQPTV
MMAR_2737|M.marinum_M --GRVNNAVGGFSFVVPAGWVESDASHLDYGSALLSKMTGEPPMPGQAPP
MUL_3017|M.ulcerans_Agy99 --GRVNNAVGGFSSVVPAGWVESDASHLDYGSALLSKMTGEPPMPGQAPP
MAV_2859|M.avium_104 NAGRIPNAVGGFSYVLPAGWVESDASHLDYGSALLSKVTGPPPMPDQPPP
MAB_2436|M.abscessus_ATCC_1997 -GGRVNNDQGGFSFVVPQGWVQSDARRLTYGSALLTNPA-----------
* * **** .:* ** *:: :: **..**::
Mflv_3345|M.gilvum_PYR-GCK PPNDTSVLLGRLDLKLFAGAETDNTKAAQRLASDMGEFFMPFPGTRVNQQ
Mvan_3075|M.vanbaalenii_PYR-1 PPNDTSVLLGRLDLKLFAGAENDNTKAAQRLASDMGEFFMPFPGTRVNQQ
MSMEG_3618|M.smegmatis_MC2_155 PPNDTSVLLGRLDLKLFAGAEPDNNKAAVRLASDMGEFFMPFPGTRVNQQ
TH_1368|M.thermoresistible__bu PPNDTSILLGRLDLKLFAGAEPDNTKAANRLASDMGEFFMPYPGTRINQE
Rv1860|M.tuberculosis_H37Rv VANDTRIVLGRLDQKLYASAEATDSKAAARLGSDMGEFYMPYPGTRINQE
Mb1891|M.bovis_AF2122/97 VANDTRIVLGRLDQKLYASAEATDSKAAARLGSDMGEFYMPYPGTRINQE
MLBr_02055|M.leprae_Br4923 VATDTRIVLGRLDQKLYASAEADNIKAAVRLGSDMGEFYLPYPGTRINQE
MMAR_2737|M.marinum_M IANDTRVVLGRLDQKLYASAEATNPKAAVRLGSDMGEFFMPYPGTRINQE
MUL_3017|M.ulcerans_Agy99 IANDTRVVLGRLDQKLYASAEATNPKAAVRLGSDMGEFFMPYPGTRINQE
MAV_2859|M.avium_104 VANDTRIVMGRLDQKLYASAEANNAKAAVRLGSDMGEFFMPYPGTRINQD
MAB_2436|M.abscessus_ATCC_1997 -APNGSILLGRLDLKLFAGAEPDNQKAARRLASDMGEFFMPYPGNRVNQE
. : :::**** **:*.** : *** **.******::*:**.*:**:
Mflv_3345|M.gilvum_PYR-GCK VVPLD-ANGMTGVASYYEVKFTDTNKPNGQIWAGVVGAPVAPGTPRGQRT
Mvan_3075|M.vanbaalenii_PYR-1 VVPLD-NN---GVASYYEVKFTDTNKPNGQIWAGVVGEPVAPGTPRGQRT
MSMEG_3618|M.smegmatis_MC2_155 TVQLN-ADGMPGVASYYEVKFTDANKPAGQIWAGVVGQPVAPGTPRGQRT
TH_1368|M.thermoresistible__bu TVPLN-AEGMQGSAAYYEVEFTDENRPNGQIWAGVVGSPTPPGTPRGQRA
Rv1860|M.tuberculosis_H37Rv TVSLD-ANGVSGSASYYEVKFSDPSKPNGQIWTGVIGS--PAANAPDAGP
Mb1891|M.bovis_AF2122/97 TVSLD-ANGVSGSASYYEVKFSDPSKPNGQIWTGVIGS--PAANAPDAGP
MLBr_02055|M.leprae_Br4923 TIPLH-ANGIAGSASYYEVKFSDPNKPIGQICTSVVGS--PAASTPDVGP
MMAR_2737|M.marinum_M TIPLN-ANGITGSASYYEVKFSDESKPNGQIWTGVVGT--PAGSTPNEGP
MUL_3017|M.ulcerans_Agy99 TIPLN-ANGITGSASYYEVKFSDESKPNGQIWTGVVGT--PAGSTPNEGP
MAV_2859|M.avium_104 STPLNGANGSTGSASYYEVKFSDASKPNGQIWTGVIGS--ANG-----GN
MAB_2436|M.abscessus_ATCC_1997 DQSFD-VAGMSAASSYYEVKFDDAAKEPGQIWAAAVGK-----------G
:. . ::****:* * : *** :..:*
Mflv_3345|M.gilvum_PYR-GCK PERWFVVWLGTATNPVPQGEAVTLANSIRPWAPPPPPP-AD---------
Mvan_3075|M.vanbaalenii_PYR-1 PERWFVVWLGTATNPIPQAEAVTLANSIRPWTPPPPPPPAD---------
MSMEG_3618|M.smegmatis_MC2_155 PERWFVVWLGTANNPIDKDAAVALANSIRPWAPPPPPPPAP---------
TH_1368|M.thermoresistible__bu PERWFVVWLGSENNPVDKAAAVALAESIRPWEPPPAPP------------
Rv1860|M.tuberculosis_H37Rv PQRWFVVWLGTANNPVDKGAAKALAESIRPLVAP-PPAPAP---------
Mb1891|M.bovis_AF2122/97 PQRWFVVWLGTANNPVDKGAAKALAESIRPLVAP-PPAPAP---------
MLBr_02055|M.leprae_Br4923 SQRWFVVWLGTSNNPVDKGAAKELAESIRSEMAP-IPASVS---------
MMAR_2737|M.marinum_M PQRWFVVWLGTSNDPVDKGAAKVLAESIRPWMPP--PAPAP---------
MUL_3017|M.ulcerans_Agy99 PQRWFVVWLGTSNDPVDKGAAKVLAESIRPWMPPPAPAPAP---------
MAV_2859|M.avium_104 AQRWFVVWLGTSNDPVDKVAAKALAESIQAWTPPPAPPAAPGGPGAPAPG
MAB_2436|M.abscessus_ATCC_1997 KDRWFIVWLGTAASPVDKGVAKALTESIRPWTPPTPPTPSAAPPADP---
:***:****: .*: : * *::**:. .* *.
Mflv_3345|M.gilvum_PYR-GCK ----------PNAPVPPADPNAPPADPNAAPPRPAVGVP--------VPV
Mvan_3075|M.vanbaalenii_PYR-1 ----------PNAPVPPADPNAPPPDPNAPAPRPAVGVP--------VPV
MSMEG_3618|M.smegmatis_MC2_155 ----------ADPADPNAAP--PPPDPNAPPARPGVGVP--------VPV
TH_1368|M.thermoresistible__bu ----------ADPAGPQAQ-----PDPDAPPARPGVGVP--------VPV
Rv1860|M.tuberculosis_H37Rv -----------APAEPAP---------APAPAGEVAPTP-----------
Mb1891|M.bovis_AF2122/97 -----------APAEPAP---------APAPAGEVAPTP-----------
MLBr_02055|M.leprae_Br4923 -----------AP----------------APVG-----------------
MMAR_2737|M.marinum_M -----------APGEPAPQPGAPEPVPAPAPAPAAGVAP-----------
MUL_3017|M.ulcerans_Agy99 -----------APGEPAPQPGAPEPVPAPAPAPAAGVAP-----------
MAV_2859|M.avium_104 APGAPAPGAPAAPGAPAPAAPAPAAPGAPAAPGAPAPAPGQAPAVEVSPT
MAB_2436|M.abscessus_ATCC_1997 ----------NQPAPPPADPNQPPPPPADPNQPPAPPAPTAPAAPAAEPA
. .
Mflv_3345|M.gilvum_PYR-GCK DPNTAPGMLPPA---------
Mvan_3075|M.vanbaalenii_PYR-1 DPNTAPGMLPPA---------
MSMEG_3618|M.smegmatis_MC2_155 T-DAPPEMMPPA---------
TH_1368|M.thermoresistible__bu T-DAPPEMMPPA---------
Rv1860|M.tuberculosis_H37Rv TTPTPQRTLPA----------
Mb1891|M.bovis_AF2122/97 TTPTPQRTLPA----------
MLBr_02055|M.leprae_Br4923 ---------------------
MMAR_2737|M.marinum_M TVAPAPRTQPT----------
MUL_3017|M.ulcerans_Agy99 TVAPAPRTQPT----------
MAV_2859|M.avium_104 PTPTPQQTLSA----------
MAB_2436|M.abscessus_ATCC_1997 APGQPAPPTPPAAPPAPGVPV