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MRIDNADLADVLVLTPTPFRDERGLFTRTFDAALFDAHLGTPGLSARFVQDSQSRSVRGVIRGMHGRSGR GEAKLVRCAHGAIHDVLVDIRPGSVTFGRQQAFLLDDNDFRHLYVPPGFLHGFQALTATADVCYRIDRPH DPSENLAVAHDDPDLAIDWPLAGAIVSAQDRRAPRWADLLMQLS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0213 | - | - | 100% (184) | dTDP-4-dehydrorhamnose 3,5-epimerase |
| M. vanbaalenii PYR-1 | Mvan_1364 | - | 2e-20 | 40.24% (169) | dTDP-4-dehydrorhamnose 3,5-epimerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3494 | rmlC | 2e-25 | 38.80% (183) | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC |
| M. gilvum PYR-GCK | Mflv_3297 | - | 8e-06 | 29.75% (158) | dTDP-4-dehydrorhamnose reductase |
| M. tuberculosis H37Rv | Rv3465 | rmlC | 2e-25 | 38.80% (183) | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC |
| M. leprae Br4923 | MLBr_01965 | rmlC | 8e-25 | 35.52% (183) | dTDP-4-dehydrorhamnose 3,5-epimerase |
| M. abscessus ATCC 19977 | MAB_3780 | - | 8e-21 | 35.84% (173) | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC |
| M. marinum M | MMAR_1081 | rmlC | 7e-22 | 40.24% (164) | dTDP-4-dehydrorhamnose 3,5-epimerase, RmlC |
| M. avium 104 | MAV_4407 | rfbC | 1e-21 | 38.89% (162) | dTDP-4-dehydrorhamnose 3,5-epimerase |
| M. smegmatis MC2 155 | MSMEG_5977 | rfbC | 2e-83 | 78.80% (184) | dTDP-4-dehydrorhamnose 3,5-epimerase |
| M. thermoresistible (build 8) | TH_0329 | rmlC | 4e-24 | 39.88% (168) | dTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE RMLC |
| M. ulcerans Agy99 | MUL_0839 | rmlC | 1e-21 | 39.63% (164) | dTDP-4-dehydrorhamnose 3,5-epimerase, RmlC |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0213|M.vanbaalenii_PYR-1 ------------MRIDNADLADVLVLTPTPFRDERGLFTRTFDAALFDAH
MSMEG_5977|M.smegmatis_MC2_155 ------------MRIEGADLADVLVLVPEPFRDERGLFTRTFDAHIFDDH
Mb3494|M.bovis_AF2122/97 ------------MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAF
Rv3465|M.tuberculosis_H37Rv ------------MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAF
MMAR_1081|M.marinum_M ------------MQARELKVPGAWEITPTIHGDSRGMFFEWLTDSGFTAF
MUL_0839|M.ulcerans_Agy99 ------------MQARELKVPGAWEITPTIHGDSRGMFFEWLTDSGFTAF
MAV_4407|M.avium_104 ------------MSARELKIPGAWEITPTVHGDARGHFFEWLTDKGFRSF
MLBr_01965|M.leprae_Br4923 ------------MNVKELDISGAWEITPTIHSDSRGMFFEWLTASRFSAF
TH_0329|M.thermoresistible__bu VTVPENVPQNVPENVRALRVPGAWEITPRLHEDARGVFFEWFTDAQFSAF
MAB_3780|M.abscessus_ATCC_1997 ------------MKIRELSVPGSFEITPVQHHDSRGVFLELFKGPALAEA
Mflv_3297|M.gilvum_PYR-GCK -----MTDFGKTLRAVETSIPGLTLWDLPVHGDNRGWFKENWQRAKMVAA
:.. . * ** * . :
Mvan_0213|M.vanbaalenii_PYR-1 LGTPGLSARFVQDSQSR-SVRGVIRGMHGRSGR-GEAKLVRCAHGAIHDV
MSMEG_5977|M.smegmatis_MC2_155 LGRPGVSASFVQDSQSR-SSQGVVRGMHGRSER-GEAKLVRCAHGAVHDV
Mb3494|M.bovis_AF2122/97 AGHS---LDVRQVNCSV-SSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDV
Rv3465|M.tuberculosis_H37Rv AGHS---LDVRQVNCSV-SSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDV
MMAR_1081|M.marinum_M CGHR---FDVRQANCSV-SSAGVLRGLHFAELPPSQAKYVTCVSGAVFDV
MUL_0839|M.ulcerans_Agy99 CGHR---FDVRQANCSV-SSAGVLRGLHFAELPPSQSKYVTCVSGAVFDV
MAV_4407|M.avium_104 AGHR---LDVRQANCSV-SAAGVLRGLHFAQVPPSQAKYVTCVRGSVFDV
MLBr_01965|M.leprae_Br4923 TGHR---LDVRQANCSV-SSAGVLRGLHFAQVPPSQAKYVTCVTGSVFDV
TH_0329|M.thermoresistible__bu AGHR---FDLRQANCSV-SAKGVLRGLHFAEVPPSQAKYVTCVTGAVFDV
MAB_3780|M.abscessus_ATCC_1997 IGHP---FELQQANCSV-SAAGSLRGIHFADVPPGQAKYVTCLTGSVYDV
Mflv_3297|M.gilvum_PYR-GCK GLPD---FGPVQNNISFNQAPGTLRGIH----AEPWDKFISVGSGRIFGA
* . * . * :**:* * : * :...
Mvan_0213|M.vanbaalenii_PYR-1 LVDIRPGSVTFGRQQAFLLDDNDFRHLYVPPGFLHGFQALTATADVCYRI
MSMEG_5977|M.smegmatis_MC2_155 LVDIRPDSPTFGRQQAFLLDDKDFRHLYVPPGFLHGFQALTAIADVCYRI
Mb3494|M.bovis_AF2122/97 VVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLC
Rv3465|M.tuberculosis_H37Rv VVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLC
MMAR_1081|M.marinum_M VVDIRLGSPTFGQWDSVLLDDR-HRSIYISEGLAHGFLALQDKSTVMYMC
MUL_0839|M.ulcerans_Agy99 VVDIRLGSPTFGQWDSVLLDDR-HRSIYISEGLAHGFLALQDKSTVMYMC
MAV_4407|M.avium_104 VVDIRVGSPTFGQWDSVLLDDAEHRTIYISEGLGHGFLALQDNSTVMYLC
MLBr_01965|M.leprae_Br4923 VVDIRLGSPTFGCWTSITLNDSNRKTIYISESLAHGFLALQDNSTVMYLC
TH_0329|M.thermoresistible__bu VVDIRVGSPTFGQWDAVLLDGANRKSVYISEGLAHGFLALEDTSTVMYLC
MAB_3780|M.abscessus_ATCC_1997 VVDIRVGSPTFGAWDAVLLDPRDRRAVYVPEGVGHGFLALEDDSTVVYLC
Mflv_3297|M.gilvum_PYR-GCK WVDLRSG-PTFGTVFTAEIDPS--RAVFVPRGVGNAFQTLEPETVYVYLV
**:* . *** : :: : :::. .. :.* :* : *
Mvan_0213|M.vanbaalenii_PYR-1 DRPHDPSE-NLAVAHDDPDLAIDWPLAGA-------IVSAQDRRAP----
MSMEG_5977|M.smegmatis_MC2_155 DRPHDPSE-DLAVAYNDPDLGIDWPLPVT-------MVSPRDAGAG----
Mb3494|M.bovis_AF2122/97 SAEYNPQR-EHTICATDPTLAVDWPLVDG----AAPSLSDRDAAAPSFED
Rv3465|M.tuberculosis_H37Rv SAEYNPQR-EHTICATDPTLAVDWPLVDG----AAPSLSDRDAAAPSFED
MMAR_1081|M.marinum_M SAEYNPQR-EHTICATDPELAIDWPLVDG----APPSLSERDAAAGSLDE
MUL_0839|M.ulcerans_Agy99 SAEYNPQR-EHTICATDPELAIDWPLVDG----APPSLSERDAAAGSLDE
MAV_4407|M.avium_104 SAEYNPGR-EHTICATDPALGIDWPLVAG----AAPTLSERDAAAPSLEE
MLBr_01965|M.leprae_Br4923 SAEYNPAR-EHAICATDPDLAIDWPVVDG----VDTHLSKRDATAPNLDD
TH_0329|M.thermoresistible__bu SAPYTPDR-EHTVAALDPAIGIEWPTLDAP---AGRVLSERDAAAPTLVE
MAB_3780|M.abscessus_ATCC_1997 SAGYAPGR-EHGIDPLDPTVGIQWPTRRPDGTELSLLVSEKDGAAPSLLD
Mflv_3297|M.gilvum_PYR-GCK NDHYSPGVGYPSLNPGDEALAIEWPIPLDR-----AEMSEKDRAQPPLSE
. : * : * :.::** :* :*
Mvan_0213|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5977|M.smegmatis_MC2_155 --------------------------------------------------
Mb3494|M.bovis_AF2122/97 VRAS-------------------------------------------GLL
Rv3465|M.tuberculosis_H37Rv VRAS-------------------------------------------GLL
MMAR_1081|M.marinum_M VRAS-------------------------------------------GVL
MUL_0839|M.ulcerans_Agy99 VRAS-------------------------------------------GVL
MAV_4407|M.avium_104 VRAS-------------------------------------------GLL
MLBr_01965|M.leprae_Br4923 IRAS-------------------------------------------GLL
TH_0329|M.thermoresistible__bu AEAA-------------------------------------------GLL
MAB_3780|M.abscessus_ATCC_1997 ARDS-------------------------------------------GLL
Mflv_3297|M.gilvum_PYR-GCK VTPVPGPKTLVLGADGQLGRALRAAYAEAPHVEFATRAELDLCAPDLDSA
Mvan_0213|M.vanbaalenii_PYR-1 -RWADLLMQLS---------------------------------------
MSMEG_5977|M.smegmatis_MC2_155 -SWSDLIRHMS---------------------------------------
Mb3494|M.bovis_AF2122/97 PRWEQTQRFIGEMRGT----------------------------------
Rv3465|M.tuberculosis_H37Rv PRWEQTQRFIGEMRGT----------------------------------
MMAR_1081|M.marinum_M PTWEETQRFIDGLRGT----------------------------------
MUL_0839|M.ulcerans_Agy99 PTWEETQRFIDGLRGT----------------------------------
MAV_4407|M.avium_104 PTWAETQAFIEGLPR-----------------------------------
MLBr_01965|M.leprae_Br4923 PTWDETQNFIANLGSK----------------------------------
TH_0329|M.thermoresistible__bu PSWEETRAFVASLRRHG---------------------------------
MAB_3780|M.abscessus_ATCC_1997 PDAAEVQAFLDGLSG-----------------------------------
Mflv_3297|M.gilvum_PYR-GCK RRWRDYDTIVNAAAYTAVDAAETSEGRTAAWTVNVTGVAALARVATAHGI
: :
Mvan_0213|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5977|M.smegmatis_MC2_155 --------------------------------------------------
Mb3494|M.bovis_AF2122/97 --------------------------------------------------
Rv3465|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1081|M.marinum_M --------------------------------------------------
MUL_0839|M.ulcerans_Agy99 --------------------------------------------------
MAV_4407|M.avium_104 --------------------------------------------------
MLBr_01965|M.leprae_Br4923 --------------------------------------------------
TH_0329|M.thermoresistible__bu --------------------------------------------------
MAB_3780|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3297|M.gilvum_PYR-GCK TLVHVSSDYVFDGSAASPYREDDPLSPLGVYGQTKAAGDQLVSTVPRHYV
Mvan_0213|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5977|M.smegmatis_MC2_155 --------------------------------------------------
Mb3494|M.bovis_AF2122/97 --------------------------------------------------
Rv3465|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1081|M.marinum_M --------------------------------------------------
MUL_0839|M.ulcerans_Agy99 --------------------------------------------------
MAV_4407|M.avium_104 --------------------------------------------------
MLBr_01965|M.leprae_Br4923 --------------------------------------------------
TH_0329|M.thermoresistible__bu --------------------------------------------------
MAB_3780|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3297|M.gilvum_PYR-GCK VRTSWVVGEGRNFVQTMLSLAAKGVDPAVVDDQFGRLTFTSELARAVRHL
Mvan_0213|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5977|M.smegmatis_MC2_155 --------------------------------------------------
Mb3494|M.bovis_AF2122/97 --------------------------------------------------
Rv3465|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1081|M.marinum_M --------------------------------------------------
MUL_0839|M.ulcerans_Agy99 --------------------------------------------------
MAV_4407|M.avium_104 --------------------------------------------------
MLBr_01965|M.leprae_Br4923 --------------------------------------------------
TH_0329|M.thermoresistible__bu --------------------------------------------------
MAB_3780|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3297|M.gilvum_PYR-GCK TESRAPYGTYNVSGSGTERTWADIARRTFDLAGHDPRRVRGVSTAEYFSA
Mvan_0213|M.vanbaalenii_PYR-1 -----------------------------------------------
MSMEG_5977|M.smegmatis_MC2_155 -----------------------------------------------
Mb3494|M.bovis_AF2122/97 -----------------------------------------------
Rv3465|M.tuberculosis_H37Rv -----------------------------------------------
MMAR_1081|M.marinum_M -----------------------------------------------
MUL_0839|M.ulcerans_Agy99 -----------------------------------------------
MAV_4407|M.avium_104 -----------------------------------------------
MLBr_01965|M.leprae_Br4923 -----------------------------------------------
TH_0329|M.thermoresistible__bu -----------------------------------------------
MAB_3780|M.abscessus_ATCC_1997 -----------------------------------------------
Mflv_3297|M.gilvum_PYR-GCK ATAPVAPRPARSVLDLGKIEATGFWPADMDETLTDYVRAATLHTQSV