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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_0329 | rmlC | - | 100% (217) | dTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE RMLC (dTDP-4-KETO-6-DEOXYGLUCOSE 3,5-EPIMERASE) (dTDP-L-RHAMNOSE SYNTHETASE) (THYMIDINE DIPHOSPHO-4-KETO-RHAMNOSE 3,5-EPIMERASE) |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3494 | rmlC | 3e-79 | 66.16% (198) | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC |
M. gilvum PYR-GCK | Mflv_3297 | - | 6e-12 | 32.02% (178) | dTDP-4-dehydrorhamnose reductase |
M. tuberculosis H37Rv | Rv3465 | rmlC | 3e-79 | 66.16% (198) | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC |
M. leprae Br4923 | MLBr_01965 | rmlC | 3e-78 | 65.83% (199) | dTDP-4-dehydrorhamnose 3,5-epimerase |
M. abscessus ATCC 19977 | MAB_3780 | - | 3e-67 | 60.40% (202) | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC |
M. marinum M | MMAR_1081 | rmlC | 2e-81 | 71.21% (198) | dTDP-4-dehydrorhamnose 3,5-epimerase, RmlC |
M. avium 104 | MAV_4407 | rfbC | 5e-84 | 72.14% (201) | dTDP-4-dehydrorhamnose 3,5-epimerase |
M. smegmatis MC2 155 | MSMEG_1510 | - | 7e-81 | 71.00% (200) | dTDP-4-dehydrorhamnose 3,5-epimerase |
M. ulcerans Agy99 | MUL_0839 | rmlC | 3e-81 | 70.71% (198) | dTDP-4-dehydrorhamnose 3,5-epimerase, RmlC |
M. vanbaalenii PYR-1 | Mvan_1364 | - | 6e-77 | 66.50% (203) | dTDP-4-dehydrorhamnose 3,5-epimerase |
CLUSTAL 2.0.9 multiple sequence alignment Mb3494|M.bovis_AF2122/97 ------------MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAF Rv3465|M.tuberculosis_H37Rv ------------MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAF MMAR_1081|M.marinum_M ------------MQARELKVPGAWEITPTIHGDSRGMFFEWLTDSGFTAF MUL_0839|M.ulcerans_Agy99 ------------MQARELKVPGAWEITPTIHGDSRGMFFEWLTDSGFTAF MLBr_01965|M.leprae_Br4923 ------------MNVKELDISGAWEITPTIHSDSRGMFFEWLTASRFSAF MAV_4407|M.avium_104 ------------MSARELKIPGAWEITPTVHGDARGHFFEWLTDKGFRSF TH_0329|M.thermoresistible__bu VTVPENVPQNVPENVRALRVPGAWEITPRLHEDARGVFFEWFTDAQFSAF MSMEG_1510|M.smegmatis_MC2_155 ------------MTARELSIAGAWEITPVLRTDSRGLFFEWFTDAGFTEF Mvan_1364|M.vanbaalenii_PYR-1 ------------MNVRELTIPGAWEITPVVHTDARGAFFEWFTDAGFTAI MAB_3780|M.abscessus_ATCC_1997 ------------MKIRELSVPGSFEITPVQHHDSRGVFLELFKGPALAEA Mflv_3297|M.gilvum_PYR-GCK -----MTDFGKTLRAVETSIPGLTLWDLPVHGDNRGWFKENWQRAKMVAA :.* : * ** * * : Mb3494|M.bovis_AF2122/97 AGHSLDVRQVNCSVSSA-GVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVD Rv3465|M.tuberculosis_H37Rv AGHSLDVRQVNCSVSSA-GVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVD MMAR_1081|M.marinum_M CGHRFDVRQANCSVSSA-GVLRGLHFAELPPSQAKYVTCVSGAVFDVVVD MUL_0839|M.ulcerans_Agy99 CGHRFDVRQANCSVSSA-GVLRGLHFAELPPSQSKYVTCVSGAVFDVVVD MLBr_01965|M.leprae_Br4923 TGHRLDVRQANCSVSSA-GVLRGLHFAQVPPSQAKYVTCVTGSVFDVVVD MAV_4407|M.avium_104 AGHRLDVRQANCSVSAA-GVLRGLHFAQVPPSQAKYVTCVRGSVFDVVVD TH_0329|M.thermoresistible__bu AGHRFDLRQANCSVSAK-GVLRGLHFAEVPPSQAKYVTCVTGAVFDVVVD MSMEG_1510|M.smegmatis_MC2_155 AGHQFDMRQANCSVSAR-GVLRGVHFAQVPPSQAKYVTCVRGAVFDVVVD Mvan_1364|M.vanbaalenii_PYR-1 TGHRLDLRQANCSVSRA-GVLRGVHFAQLPPSQAKYVSCVRGAVVDVVVD MAB_3780|M.abscessus_ATCC_1997 IGHPFELQQANCSVSAA-GSLRGIHFADVPPGQAKYVTCLTGSVYDVVVD Mflv_3297|M.gilvum_PYR-GCK GLPDFGPVQNNISFNQAPGTLRGIHAEPWD----KFISVGSGRIFGAWVD : * * *.. * ***:* *::: * : .. ** Mb3494|M.bovis_AF2122/97 IREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAE Rv3465|M.tuberculosis_H37Rv IREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAE MMAR_1081|M.marinum_M IRLGSPTFGQWDSVLLDDR-HRSIYISEGLAHGFLALQDKSTVMYMCSAE MUL_0839|M.ulcerans_Agy99 IRLGSPTFGQWDSVLLDDR-HRSIYISEGLAHGFLALQDKSTVMYMCSAE MLBr_01965|M.leprae_Br4923 IRLGSPTFGCWTSITLNDSNRKTIYISESLAHGFLALQDNSTVMYLCSAE MAV_4407|M.avium_104 IRVGSPTFGQWDSVLLDDAEHRTIYISEGLGHGFLALQDNSTVMYLCSAE TH_0329|M.thermoresistible__bu IRVGSPTFGQWDAVLLDGANRKSVYISEGLAHGFLALEDTSTVMYLCSAP MSMEG_1510|M.smegmatis_MC2_155 IRVGSPTFGQWDAVLLDDKDRRSIYISEGLGHAFLALDDDSTVMYLCSAP Mvan_1364|M.vanbaalenii_PYR-1 IRVGSPTFGRWDAVVLDDETHRSVYLSEGLGHAFLALHDDSVVTYLCSAG MAB_3780|M.abscessus_ATCC_1997 IRVGSPTFGAWDAVLLDPRDRRAVYVPEGVGHGFLALEDDSTVVYLCSAG Mflv_3297|M.gilvum_PYR-GCK LRSG-PTFGTVFTAEIDPS--RAVFVPRGVGNAFQTLEPETVYVYLVNDH :* * **** : :: :::::...:.:.* :*. :. *: . Mb3494|M.bovis_AF2122/97 YNPQR-EHTICATDPTLAVDWPLVDG----AAPSLSDRDAAAPSFEDVR- Rv3465|M.tuberculosis_H37Rv YNPQR-EHTICATDPTLAVDWPLVDG----AAPSLSDRDAAAPSFEDVR- MMAR_1081|M.marinum_M YNPQR-EHTICATDPELAIDWPLVDG----APPSLSERDAAAGSLDEVR- MUL_0839|M.ulcerans_Agy99 YNPQR-EHTICATDPELAIDWPLVDG----APPSLSERDAAAGSLDEVR- MLBr_01965|M.leprae_Br4923 YNPAR-EHAICATDPDLAIDWPVVDG----VDTHLSKRDATAPNLDDIR- MAV_4407|M.avium_104 YNPGR-EHTICATDPALGIDWPLVAG----AAPTLSERDAAAPSLEEVR- TH_0329|M.thermoresistible__bu YTPDR-EHTVAALDPAIGIEWPTLDAP---AGRVLSERDAAAPTLVEAE- MSMEG_1510|M.smegmatis_MC2_155 YAPQR-EHTVRPTD--FGIEWPEVP------ELILSDRDAQAPSLAEAQ- Mvan_1364|M.vanbaalenii_PYR-1 YDPAR-EHTIDPLDPALEIDWNAWPSRAADGELILSDRDRAAPSLEQAR- MAB_3780|M.abscessus_ATCC_1997 YAPGR-EHGIDPLDPTVGIQWPTRRPDGTELSLLVSEKDGAAPSLLDAR- Mflv_3297|M.gilvum_PYR-GCK YSPGVGYPSLNPGDEALAIEWPIPLDR-----AEMSEKDRAQPPLSEVTP * * : . * . ::* :*.:* : : Mb3494|M.bovis_AF2122/97 -------------------------------------------------- Rv3465|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1081|M.marinum_M -------------------------------------------------- MUL_0839|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01965|M.leprae_Br4923 -------------------------------------------------- MAV_4407|M.avium_104 -------------------------------------------------- TH_0329|M.thermoresistible__bu -------------------------------------------------- MSMEG_1510|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1364|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3780|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_3297|M.gilvum_PYR-GCK VPGPKTLVLGADGQLGRALRAAYAEAPHVEFATRAELDLCAPDLDSARRW Mb3494|M.bovis_AF2122/97 --------------------ASGLLPRWEQTQRFIGEMRGT--------- Rv3465|M.tuberculosis_H37Rv --------------------ASGLLPRWEQTQRFIGEMRGT--------- MMAR_1081|M.marinum_M --------------------ASGVLPTWEETQRFIDGLRGT--------- MUL_0839|M.ulcerans_Agy99 --------------------ASGVLPTWEETQRFIDGLRGT--------- MLBr_01965|M.leprae_Br4923 --------------------ASGLLPTWDETQNFIANLGSK--------- MAV_4407|M.avium_104 --------------------ASGLLPTWAETQAFIEGLPR---------- TH_0329|M.thermoresistible__bu --------------------AAGLLPSWEETRAFVASLRRHG-------- MSMEG_1510|M.smegmatis_MC2_155 --------------------AAGVLPTWADCQAFVETLRRNLVS------ Mvan_1364|M.vanbaalenii_PYR-1 --------------------TSGLLPTWEQTKKFVDGLRTGR-------- MAB_3780|M.abscessus_ATCC_1997 --------------------DSGLLPDAAEVQAFLDGLSG---------- Mflv_3297|M.gilvum_PYR-GCK RDYDTIVNAAAYTAVDAAETSEGRTAAWTVNVTGVAALARVATAHGITLV * . : : Mb3494|M.bovis_AF2122/97 -------------------------------------------------- Rv3465|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1081|M.marinum_M -------------------------------------------------- MUL_0839|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01965|M.leprae_Br4923 -------------------------------------------------- MAV_4407|M.avium_104 -------------------------------------------------- TH_0329|M.thermoresistible__bu -------------------------------------------------- MSMEG_1510|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1364|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3780|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_3297|M.gilvum_PYR-GCK HVSSDYVFDGSAASPYREDDPLSPLGVYGQTKAAGDQLVSTVPRHYVVRT Mb3494|M.bovis_AF2122/97 -------------------------------------------------- Rv3465|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1081|M.marinum_M -------------------------------------------------- MUL_0839|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01965|M.leprae_Br4923 -------------------------------------------------- MAV_4407|M.avium_104 -------------------------------------------------- TH_0329|M.thermoresistible__bu -------------------------------------------------- MSMEG_1510|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1364|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3780|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_3297|M.gilvum_PYR-GCK SWVVGEGRNFVQTMLSLAAKGVDPAVVDDQFGRLTFTSELARAVRHLTES Mb3494|M.bovis_AF2122/97 -------------------------------------------------- Rv3465|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1081|M.marinum_M -------------------------------------------------- MUL_0839|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01965|M.leprae_Br4923 -------------------------------------------------- MAV_4407|M.avium_104 -------------------------------------------------- TH_0329|M.thermoresistible__bu -------------------------------------------------- MSMEG_1510|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1364|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3780|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_3297|M.gilvum_PYR-GCK RAPYGTYNVSGSGTERTWADIARRTFDLAGHDPRRVRGVSTAEYFSAATA Mb3494|M.bovis_AF2122/97 -------------------------------------------- Rv3465|M.tuberculosis_H37Rv -------------------------------------------- MMAR_1081|M.marinum_M -------------------------------------------- MUL_0839|M.ulcerans_Agy99 -------------------------------------------- MLBr_01965|M.leprae_Br4923 -------------------------------------------- MAV_4407|M.avium_104 -------------------------------------------- TH_0329|M.thermoresistible__bu -------------------------------------------- MSMEG_1510|M.smegmatis_MC2_155 -------------------------------------------- Mvan_1364|M.vanbaalenii_PYR-1 -------------------------------------------- MAB_3780|M.abscessus_ATCC_1997 -------------------------------------------- Mflv_3297|M.gilvum_PYR-GCK PVAPRPARSVLDLGKIEATGFWPADMDETLTDYVRAATLHTQSV