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M. smegmatis MC2 155 MSMEG_5977 (rfbC)

annotation: dTDP-4-dehydrorhamnose 3,5-epimerase
coordinates: 6040647 - 6041201
length: 184

VRIEGADLADVLVLVPEPFRDERGLFTRTFDAHIFDDHLGRPGVSASFVQDSQSRSSQGVVRGMHGRSER
GEAKLVRCAHGAVHDVLVDIRPDSPTFGRQQAFLLDDKDFRHLYVPPGFLHGFQALTAIADVCYRIDRPH
DPSEDLAVAYNDPDLGIDWPLPVTMVSPRDAGAGSWSDLIRHMS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5977rfbC-100% (184)dTDP-4-dehydrorhamnose 3,5-epimerase
M. smegmatis MC2 155MSMEG_1510-1e-2238.73% (173) dTDP-4-dehydrorhamnose 3,5-epimerase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3494rmlC1e-2538.98% (177) dTDP-4-dehydrorhamnose 3,5-epimerase RmlC
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv3465rmlC1e-2538.98% (177) dTDP-4-dehydrorhamnose 3,5-epimerase RmlC
M. leprae Br4923MLBr_01965rmlC3e-2233.88% (183) dTDP-4-dehydrorhamnose 3,5-epimerase
M. abscessus ATCC 19977MAB_3780-1e-2134.95% (186) dTDP-4-dehydrorhamnose 3,5-epimerase RmlC
M. marinum MMMAR_1081rmlC6e-2237.65% (170) dTDP-4-dehydrorhamnose 3,5-epimerase, RmlC
M. avium 104MAV_4407rfbC8e-2241.04% (134) dTDP-4-dehydrorhamnose 3,5-epimerase
M. thermoresistible (build 8)TH_0329rmlC8e-2237.58% (165) dTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE RMLC
M. ulcerans Agy99MUL_0839rmlC9e-2237.06% (170) dTDP-4-dehydrorhamnose 3,5-epimerase, RmlC
M. vanbaalenii PYR-1Mvan_0213-1e-8378.80% (184) dTDP-4-dehydrorhamnose 3,5-epimerase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3494|M.bovis_AF2122/97            ------------MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAF
Rv3465|M.tuberculosis_H37Rv         ------------MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAF
MMAR_1081|M.marinum_M               ------------MQARELKVPGAWEITPTIHGDSRGMFFEWLTDSGFTAF
MUL_0839|M.ulcerans_Agy99           ------------MQARELKVPGAWEITPTIHGDSRGMFFEWLTDSGFTAF
MAV_4407|M.avium_104                ------------MSARELKIPGAWEITPTVHGDARGHFFEWLTDKGFRSF
MLBr_01965|M.leprae_Br4923          ------------MNVKELDISGAWEITPTIHSDSRGMFFEWLTASRFSAF
TH_0329|M.thermoresistible__bu      VTVPENVPQNVPENVRALRVPGAWEITPRLHEDARGVFFEWFTDAQFSAF
MAB_3780|M.abscessus_ATCC_1997      ------------MKIRELSVPGSFEITPVQHHDSRGVFLELFKGPALAEA
MSMEG_5977|M.smegmatis_MC2_155      ------------MRIEGADLADVLVLVPEPFRDERGLFTRTFDAHIFDDH
Mvan_0213|M.vanbaalenii_PYR-1       ------------MRIDNADLADVLVLTPTPFRDERGLFTRTFDAALFDAH
                                                       :..   :.*  . * ** * . :    :   

Mb3494|M.bovis_AF2122/97            AGHS---LDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVV
Rv3465|M.tuberculosis_H37Rv         AGHS---LDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVV
MMAR_1081|M.marinum_M               CGHR---FDVRQANCSVSSAGVLRGLHFAELPPSQAKYVTCVSGAVFDVV
MUL_0839|M.ulcerans_Agy99           CGHR---FDVRQANCSVSSAGVLRGLHFAELPPSQSKYVTCVSGAVFDVV
MAV_4407|M.avium_104                AGHR---LDVRQANCSVSAAGVLRGLHFAQVPPSQAKYVTCVRGSVFDVV
MLBr_01965|M.leprae_Br4923          TGHR---LDVRQANCSVSSAGVLRGLHFAQVPPSQAKYVTCVTGSVFDVV
TH_0329|M.thermoresistible__bu      AGHR---FDLRQANCSVSAKGVLRGLHFAEVPPSQAKYVTCVTGAVFDVV
MAB_3780|M.abscessus_ATCC_1997      IGHP---FELQQANCSVSAAGSLRGIHFADVPPGQAKYVTCLTGSVYDVV
MSMEG_5977|M.smegmatis_MC2_155      LGRPGVSASFVQDSQSRSSQGVVRGMHGRSER-GEAKLVRCAHGAVHDVL
Mvan_0213|M.vanbaalenii_PYR-1       LGTPGLSARFVQDSQSRSVRGVIRGMHGRSGR-GEAKLVRCAHGAIHDVL
                                     *       . * . * *  * :**:*  .   .::* * *  *::.**:

Mb3494|M.bovis_AF2122/97            VDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCS
Rv3465|M.tuberculosis_H37Rv         VDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCS
MMAR_1081|M.marinum_M               VDIRLGSPTFGQWDSVLLDDR-HRSIYISEGLAHGFLALQDKSTVMYMCS
MUL_0839|M.ulcerans_Agy99           VDIRLGSPTFGQWDSVLLDDR-HRSIYISEGLAHGFLALQDKSTVMYMCS
MAV_4407|M.avium_104                VDIRVGSPTFGQWDSVLLDDAEHRTIYISEGLGHGFLALQDNSTVMYLCS
MLBr_01965|M.leprae_Br4923          VDIRLGSPTFGCWTSITLNDSNRKTIYISESLAHGFLALQDNSTVMYLCS
TH_0329|M.thermoresistible__bu      VDIRVGSPTFGQWDAVLLDGANRKSVYISEGLAHGFLALEDTSTVMYLCS
MAB_3780|M.abscessus_ATCC_1997      VDIRVGSPTFGAWDAVLLDPRDRRAVYVPEGVGHGFLALEDDSTVVYLCS
MSMEG_5977|M.smegmatis_MC2_155      VDIRPDSPTFGRQQAFLLDDKDFRHLYVPPGFLHGFQALTAIADVCYRID
Mvan_0213|M.vanbaalenii_PYR-1       VDIRPGSVTFGRQQAFLLDDNDFRHLYVPPGFLHGFQALTATADVCYRID
                                    **** .* ***   :. *:    : :*:. .. *** **   : * *  .

Mb3494|M.bovis_AF2122/97            AEYNPQREHTICATDPTLAVDWPLVDG----AAPSLSDRDAAAPSFEDVR
Rv3465|M.tuberculosis_H37Rv         AEYNPQREHTICATDPTLAVDWPLVDG----AAPSLSDRDAAAPSFEDVR
MMAR_1081|M.marinum_M               AEYNPQREHTICATDPELAIDWPLVDG----APPSLSERDAAAGSLDEVR
MUL_0839|M.ulcerans_Agy99           AEYNPQREHTICATDPELAIDWPLVDG----APPSLSERDAAAGSLDEVR
MAV_4407|M.avium_104                AEYNPGREHTICATDPALGIDWPLVAG----AAPTLSERDAAAPSLEEVR
MLBr_01965|M.leprae_Br4923          AEYNPAREHAICATDPDLAIDWPVVDG----VDTHLSKRDATAPNLDDIR
TH_0329|M.thermoresistible__bu      APYTPDREHTVAALDPAIGIEWPTLDAP---AGRVLSERDAAAPTLVEAE
MAB_3780|M.abscessus_ATCC_1997      AGYAPGREHGIDPLDPTVGIQWPTRRPDGTELSLLVSEKDGAAPSLLDAR
MSMEG_5977|M.smegmatis_MC2_155      RPHDPSEDLAVAYNDPDLGIDWPLPVT-------MVSPRDAGAG------
Mvan_0213|M.vanbaalenii_PYR-1       RPHDPSENLAVAHDDPDLAIDWPLAGA-------IVSAQDRRAP------
                                      : * .:  :   ** :.::**            :* :*  *       

Mb3494|M.bovis_AF2122/97            ASGLLPRWEQTQRFIGEMRGT-
Rv3465|M.tuberculosis_H37Rv         ASGLLPRWEQTQRFIGEMRGT-
MMAR_1081|M.marinum_M               ASGVLPTWEETQRFIDGLRGT-
MUL_0839|M.ulcerans_Agy99           ASGVLPTWEETQRFIDGLRGT-
MAV_4407|M.avium_104                ASGLLPTWAETQAFIEGLPR--
MLBr_01965|M.leprae_Br4923          ASGLLPTWDETQNFIANLGSK-
TH_0329|M.thermoresistible__bu      AAGLLPSWEETRAFVASLRRHG
MAB_3780|M.abscessus_ATCC_1997      DSGLLPDAAEVQAFLDGLSG--
MSMEG_5977|M.smegmatis_MC2_155      ------SWSDLIRHMS------
Mvan_0213|M.vanbaalenii_PYR-1       ------RWADLLMQLS------
                                             :    :