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VRIEGADLADVLVLVPEPFRDERGLFTRTFDAHIFDDHLGRPGVSASFVQDSQSRSSQGVVRGMHGRSER GEAKLVRCAHGAVHDVLVDIRPDSPTFGRQQAFLLDDKDFRHLYVPPGFLHGFQALTAIADVCYRIDRPH DPSEDLAVAYNDPDLGIDWPLPVTMVSPRDAGAGSWSDLIRHMS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_5977 | rfbC | - | 100% (184) | dTDP-4-dehydrorhamnose 3,5-epimerase |
M. smegmatis MC2 155 | MSMEG_1510 | - | 1e-22 | 38.73% (173) | dTDP-4-dehydrorhamnose 3,5-epimerase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3494 | rmlC | 1e-25 | 38.98% (177) | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC |
M. gilvum PYR-GCK | - | - | - | - | - |
M. tuberculosis H37Rv | Rv3465 | rmlC | 1e-25 | 38.98% (177) | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC |
M. leprae Br4923 | MLBr_01965 | rmlC | 3e-22 | 33.88% (183) | dTDP-4-dehydrorhamnose 3,5-epimerase |
M. abscessus ATCC 19977 | MAB_3780 | - | 1e-21 | 34.95% (186) | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC |
M. marinum M | MMAR_1081 | rmlC | 6e-22 | 37.65% (170) | dTDP-4-dehydrorhamnose 3,5-epimerase, RmlC |
M. avium 104 | MAV_4407 | rfbC | 8e-22 | 41.04% (134) | dTDP-4-dehydrorhamnose 3,5-epimerase |
M. thermoresistible (build 8) | TH_0329 | rmlC | 8e-22 | 37.58% (165) | dTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE RMLC |
M. ulcerans Agy99 | MUL_0839 | rmlC | 9e-22 | 37.06% (170) | dTDP-4-dehydrorhamnose 3,5-epimerase, RmlC |
M. vanbaalenii PYR-1 | Mvan_0213 | - | 1e-83 | 78.80% (184) | dTDP-4-dehydrorhamnose 3,5-epimerase |
CLUSTAL 2.0.9 multiple sequence alignment Mb3494|M.bovis_AF2122/97 ------------MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAF Rv3465|M.tuberculosis_H37Rv ------------MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAF MMAR_1081|M.marinum_M ------------MQARELKVPGAWEITPTIHGDSRGMFFEWLTDSGFTAF MUL_0839|M.ulcerans_Agy99 ------------MQARELKVPGAWEITPTIHGDSRGMFFEWLTDSGFTAF MAV_4407|M.avium_104 ------------MSARELKIPGAWEITPTVHGDARGHFFEWLTDKGFRSF MLBr_01965|M.leprae_Br4923 ------------MNVKELDISGAWEITPTIHSDSRGMFFEWLTASRFSAF TH_0329|M.thermoresistible__bu VTVPENVPQNVPENVRALRVPGAWEITPRLHEDARGVFFEWFTDAQFSAF MAB_3780|M.abscessus_ATCC_1997 ------------MKIRELSVPGSFEITPVQHHDSRGVFLELFKGPALAEA MSMEG_5977|M.smegmatis_MC2_155 ------------MRIEGADLADVLVLVPEPFRDERGLFTRTFDAHIFDDH Mvan_0213|M.vanbaalenii_PYR-1 ------------MRIDNADLADVLVLTPTPFRDERGLFTRTFDAALFDAH :.. :.* . * ** * . : : Mb3494|M.bovis_AF2122/97 AGHS---LDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVV Rv3465|M.tuberculosis_H37Rv AGHS---LDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVV MMAR_1081|M.marinum_M CGHR---FDVRQANCSVSSAGVLRGLHFAELPPSQAKYVTCVSGAVFDVV MUL_0839|M.ulcerans_Agy99 CGHR---FDVRQANCSVSSAGVLRGLHFAELPPSQSKYVTCVSGAVFDVV MAV_4407|M.avium_104 AGHR---LDVRQANCSVSAAGVLRGLHFAQVPPSQAKYVTCVRGSVFDVV MLBr_01965|M.leprae_Br4923 TGHR---LDVRQANCSVSSAGVLRGLHFAQVPPSQAKYVTCVTGSVFDVV TH_0329|M.thermoresistible__bu AGHR---FDLRQANCSVSAKGVLRGLHFAEVPPSQAKYVTCVTGAVFDVV MAB_3780|M.abscessus_ATCC_1997 IGHP---FELQQANCSVSAAGSLRGIHFADVPPGQAKYVTCLTGSVYDVV MSMEG_5977|M.smegmatis_MC2_155 LGRPGVSASFVQDSQSRSSQGVVRGMHGRSER-GEAKLVRCAHGAVHDVL Mvan_0213|M.vanbaalenii_PYR-1 LGTPGLSARFVQDSQSRSVRGVIRGMHGRSGR-GEAKLVRCAHGAIHDVL * . * . * * * :**:* . .::* * * *::.**: Mb3494|M.bovis_AF2122/97 VDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCS Rv3465|M.tuberculosis_H37Rv VDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCS MMAR_1081|M.marinum_M VDIRLGSPTFGQWDSVLLDDR-HRSIYISEGLAHGFLALQDKSTVMYMCS MUL_0839|M.ulcerans_Agy99 VDIRLGSPTFGQWDSVLLDDR-HRSIYISEGLAHGFLALQDKSTVMYMCS MAV_4407|M.avium_104 VDIRVGSPTFGQWDSVLLDDAEHRTIYISEGLGHGFLALQDNSTVMYLCS MLBr_01965|M.leprae_Br4923 VDIRLGSPTFGCWTSITLNDSNRKTIYISESLAHGFLALQDNSTVMYLCS TH_0329|M.thermoresistible__bu VDIRVGSPTFGQWDAVLLDGANRKSVYISEGLAHGFLALEDTSTVMYLCS MAB_3780|M.abscessus_ATCC_1997 VDIRVGSPTFGAWDAVLLDPRDRRAVYVPEGVGHGFLALEDDSTVVYLCS MSMEG_5977|M.smegmatis_MC2_155 VDIRPDSPTFGRQQAFLLDDKDFRHLYVPPGFLHGFQALTAIADVCYRID Mvan_0213|M.vanbaalenii_PYR-1 VDIRPGSVTFGRQQAFLLDDNDFRHLYVPPGFLHGFQALTATADVCYRID **** .* *** :. *: : :*:. .. *** ** : * * . Mb3494|M.bovis_AF2122/97 AEYNPQREHTICATDPTLAVDWPLVDG----AAPSLSDRDAAAPSFEDVR Rv3465|M.tuberculosis_H37Rv AEYNPQREHTICATDPTLAVDWPLVDG----AAPSLSDRDAAAPSFEDVR MMAR_1081|M.marinum_M AEYNPQREHTICATDPELAIDWPLVDG----APPSLSERDAAAGSLDEVR MUL_0839|M.ulcerans_Agy99 AEYNPQREHTICATDPELAIDWPLVDG----APPSLSERDAAAGSLDEVR MAV_4407|M.avium_104 AEYNPGREHTICATDPALGIDWPLVAG----AAPTLSERDAAAPSLEEVR MLBr_01965|M.leprae_Br4923 AEYNPAREHAICATDPDLAIDWPVVDG----VDTHLSKRDATAPNLDDIR TH_0329|M.thermoresistible__bu APYTPDREHTVAALDPAIGIEWPTLDAP---AGRVLSERDAAAPTLVEAE MAB_3780|M.abscessus_ATCC_1997 AGYAPGREHGIDPLDPTVGIQWPTRRPDGTELSLLVSEKDGAAPSLLDAR MSMEG_5977|M.smegmatis_MC2_155 RPHDPSEDLAVAYNDPDLGIDWPLPVT-------MVSPRDAGAG------ Mvan_0213|M.vanbaalenii_PYR-1 RPHDPSENLAVAHDDPDLAIDWPLAGA-------IVSAQDRRAP------ : * .: : ** :.::** :* :* * Mb3494|M.bovis_AF2122/97 ASGLLPRWEQTQRFIGEMRGT- Rv3465|M.tuberculosis_H37Rv ASGLLPRWEQTQRFIGEMRGT- MMAR_1081|M.marinum_M ASGVLPTWEETQRFIDGLRGT- MUL_0839|M.ulcerans_Agy99 ASGVLPTWEETQRFIDGLRGT- MAV_4407|M.avium_104 ASGLLPTWAETQAFIEGLPR-- MLBr_01965|M.leprae_Br4923 ASGLLPTWDETQNFIANLGSK- TH_0329|M.thermoresistible__bu AAGLLPSWEETRAFVASLRRHG MAB_3780|M.abscessus_ATCC_1997 DSGLLPDAAEVQAFLDGLSG-- MSMEG_5977|M.smegmatis_MC2_155 ------SWSDLIRHMS------ Mvan_0213|M.vanbaalenii_PYR-1 ------RWADLLMQLS------ : :