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VDIRSGTAVSGDVKLYYEDMGDLDHPPVLLIMGLGAQMLLWRTDFCARLVAKGLRVIRYDNRDVGLSTKT ERHRPGQPLATRLVRSWLGLPSQAAYTLEDMAADAAALLDHLDVKHAHVVGASMGGMIAQIFAARFAQRT KTLAVIFSSNNHRFLPPPAPRALLALLTGPPPDSPRDVIVDNAVRVSKIIGSPAYPIPEDQVRAEAAESY DRNFHPWGIAQQFSAILGSGSLLRYDRRIVAPTVVIHGRADKLMRPFGGRAVARAINGARLVLIDGMGHD LPRQLWDRVIGELTRNFSEAG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0665c | lipG | - | 100% (301) | lipase/esterase LipG |
M. bovis AF2122 / 97 | Mb0569 | bpoC | 3e-12 | 26.62% (278) | peroxidase BpoC |
M. bovis AF2122 / 97 | Mb1935c | lipJ | 4e-07 | 25.09% (287) | lignin peroxidase LIPJ |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_5112 | - | 1e-114 | 68.00% (300) | alpha/beta hydrolase fold |
M. tuberculosis H37Rv | Rv0646c | lipG | 1e-173 | 100.00% (301) | lipase/esterase LipG |
M. leprae Br4923 | MLBr_01899 | lipG | 1e-125 | 71.62% (303) | putative hydrolase |
M. abscessus ATCC 19977 | MAB_3880 | - | 3e-90 | 54.15% (301) | lipase/esterase LipG |
M. marinum M | MMAR_0981 | lipG1 | 1e-128 | 75.60% (291) | lipase/esterase LipG1 |
M. avium 104 | MAV_4515 | - | 1e-136 | 77.67% (300) | hydrolase, alpha/beta fold family protein |
M. smegmatis MC2 155 | MSMEG_1352 | - | 1e-111 | 64.90% (302) | hydrolase, alpha/beta fold family protein |
M. thermoresistible (build 8) | TH_1861 | lipG | 1e-114 | 64.90% (302) | PROBABLE LIPASE/ESTERASE LIPG |
M. ulcerans Agy99 | MUL_0733 | lipG1 | 1e-128 | 75.26% (291) | lipase/esterase LipG1 |
M. vanbaalenii PYR-1 | Mvan_1240 | - | 1e-111 | 65.89% (299) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_5112|M.gilvum_PYR-GCK -----MQVRTGTARS-------------GELEIHYEDMGDPNDPAVLLIM Mvan_1240|M.vanbaalenii_PYR-1 -----MQIRSGTAKS-------------GDLDIFYEDMGDPNDPAVLLIM Mb0665c|M.bovis_AF2122/97 -----MDIRSGTAVS-------------GDVKLYYEDMGDLDHPPVLLIM Rv0646c|M.tuberculosis_H37Rv -----MDIRSGTAVS-------------GDVKLYYEDMGDLDHPPVLLIM MAV_4515|M.avium_104 ----MVQVRTGHAIS-------------GDLKLYYEDMGDIDDPPVLLIM MMAR_0981|M.marinum_M -----MEIRTGYAQSGVGSGATSERQPAGDLKLYYEDMGDINAPPVLLIM MUL_0733|M.ulcerans_Agy99 -----MEIRTGYAQSGVGSGATSERQPAGDLKLYYEDMGDINAPPVLLIM MLBr_01899|M.leprae_Br4923 -----MEVRSGYATS-------------GDLKLYYEDMGNVDDPPVLLIM MSMEG_1352|M.smegmatis_MC2_155 -----MQTRTGLARAG---------DADHPIDLFYEDMGDPGDPAVLLIM TH_1861|M.thermoresistible__bu -----MQIRTGFANVD---------GSPEPVDLYYEDLGDPADPPVLLIM MAB_3880|M.abscessus_ATCC_1997 MSTTAREISEMTASTAT----------VGDIELCYEEFGNPADPAVLLIM : * :.: **::*: *.***** Mflv_5112|M.gilvum_PYR-GCK GLGAQLLLWRKGFCEKLINQGLRVIRFDNRDVGLSSKLT---GHHAGAPL Mvan_1240|M.vanbaalenii_PYR-1 GLGAQLLLWRNGFCEKLINQGLRVIRFDNRDVGLSSKLH---HHRSGAPL Mb0665c|M.bovis_AF2122/97 GLGAQMLLWRTDFCARLVAKGLRVIRYDNRDVGLSTKTE---RHRPGQPL Rv0646c|M.tuberculosis_H37Rv GLGAQMLLWRTDFCARLVAKGLRVIRYDNRDVGLSTKTE---RHRPGQPL MAV_4515|M.avium_104 GLGAQLLLWRTAFCEKLVGRGLRVIRYDNRDVGLSSKTE---HRSSGQPL MMAR_0981|M.marinum_M GLGAQLLLWRTGFCQKLVDQGLRVIRYDNRDVGLSTKME---QPSARQPL MUL_0733|M.ulcerans_Agy99 GLGAQLLLWRTGFCQKPVDQGLRVIRYDNRDVGLSTKME---QPSARQPL MLBr_01899|M.leprae_Br4923 GLGAQLVLWRTAFCEKLVAQGLRVVRYDNRDVGLSSRTDSTEQPCPSQPL MSMEG_1352|M.smegmatis_MC2_155 GLGAQMLMWRTEFCEKLVDQGLRVIRFDNRDVGLSTKLS---GQRVDSPL TH_1861|M.thermoresistible__bu GLGAQLILWRDGFCRKLVERGLRVIRFDNRDVGLSSKLD---GRRERTPL MAB_3880|M.abscessus_ATCC_1997 GIGAQMVFWRPEFCQQLADQGYRVIRFDNRDCGLSTKLDG--VRAGGGSL *:***:::** ** : :* **:*:**** ***:: .* Mflv_5112|M.gilvum_PYR-GCK LPRMARSLAGLPSP-AAYTLEDMADDAAALLDHLDIDRAHVVGGSMGGMI Mvan_1240|M.vanbaalenii_PYR-1 LPRMARSFVGRPSP-AAYTLEDMADDAAALLDHLGIDTAHVVGGSMGGMI Mb0665c|M.bovis_AF2122/97 ATRLVRSWLGLPSQ-AAYTLEDMAADAAALLDHLDVKHAHVVGASMGGMI Rv0646c|M.tuberculosis_H37Rv ATRLVRSWLGLPSQ-AAYTLEDMAADAAALLDHLDVKHAHVVGASMGGMI MAV_4515|M.avium_104 VTRLLRSWLGLPSQ-SAYRLEDMADDAAAVLDHLGIDDAHIVGASMGGMI MMAR_0981|M.marinum_M MPQLIRSWLGRRSQ-TPYTLEDMADDAAALLDHLDIERAHIVGASMGGMI MUL_0733|M.ulcerans_Agy99 MPQLIRSWLGRRSQ-TPYTLEDMADDAAALLDHLDIERAHIVGASMGGMI MLBr_01899|M.leprae_Br4923 TARLIRFWLGQRNA-CAYTLEDMTDDAVALLDHLSIERAHIVGASMGGMI MSMEG_1352|M.smegmatis_MC2_155 ALRMARSFLGKRSP-AVYTLEDMADDAAALLDHLEIDRAHIVGGSMGGMI TH_1861|M.thermoresistible__bu PWRMLRSFAGLPSP-AVYTLEDMADDAAGLLDHLQIDAAHIVGASMGGMV MAB_3880|M.abscessus_ATCC_1997 IPSMAKFLAGVKITGTAYTLVDMAGDAAGLLDHLGIEQAHIVGASMGGMI : : * * * **: **..:**** :. **:**.*****: Mflv_5112|M.gilvum_PYR-GCK AQVFAARHHPRTKTLGVIFSSNNQAALPPPGPRQLAAILQRP-KGSSRDE Mvan_1240|M.vanbaalenii_PYR-1 AQVFAARHRARTGALGVIFSSNNQAALPPPGPRQLAAILQRP-KGSDREA Mb0665c|M.bovis_AF2122/97 AQIFAARFAQRTKTLAVIFSSNNHRFLPPPAPRALLALLTGPPPDSPRDV Rv0646c|M.tuberculosis_H37Rv AQIFAARFAQRTKTLAVIFSSNNHRFLPPPAPRALLALLTGPPPDSPRDV MAV_4515|M.avium_104 AQIFAARFRQRTKTLAVIFSSNNSALLPPPAPRALLALLKGPPPDSPREV MMAR_0981|M.marinum_M AQIFAARFAERTNSLAVIFSSNNRPFLPPPAPRALLAVLNGPPPGSPREV MUL_0733|M.ulcerans_Agy99 AQIFAARFAERTNSLAVIFSSNNRPFLPPPAPRALLAVLNGPPPGSPREV MLBr_01899|M.leprae_Br4923 AQIFAARFPTRTRSLAVFFSSNNRPFLPPPAPRALLALLTGPPTGSRRDV MSMEG_1352|M.smegmatis_MC2_155 AQVFASQHAARTETLGVIFSSNNQALLPPPGIRQLLSLITGPPADASRDA TH_1861|M.thermoresistible__bu AQVFAGRHAHRTRSLGVIFSSNNRPFLPPPGPRQLLSIITGPAPDAPRDE MAB_3880|M.abscessus_ATCC_1997 AQVFAAEHPDRTATVSIIMSSNNQPFLPPPGPRQLMALLKPPPEGASREQ **:**... ** ::.:::**** ****. * * ::: * .: *: Mflv_5112|M.gilvum_PYR-GCK IVDNAVRVSRIIGSPGYPAPLDRLRTDAIEGFDRSYYPAGVGRHFAAILG Mvan_1240|M.vanbaalenii_PYR-1 IIENAVRVSRIIGSPGYPAAEERLRADAIEGYDRSYYPAGVGRHFAAILG Mb0665c|M.bovis_AF2122/97 IVDNAVRVSKIIGSPAYPIPEDQVRAEAAESYDRNFHPWGIAQQFSAILG Rv0646c|M.tuberculosis_H37Rv IVDNAVRVSKIIGSPAYPIPEDQVRAEAAESYDRNFHPWGIAQQFSAILG MAV_4515|M.avium_104 IIDNAVRVGRIIGSTRYRVPEEQARAEAAEGYDRNYYPQGVARHFSAVLG MMAR_0981|M.marinum_M IIDNVVRVTRITGSPGYQPTEEWIRADAAENYDRSYYPWGIPRQFSAVLG MUL_0733|M.ulcerans_Agy99 IIDNVVRVTRITGSPGYQPTEEWIRADAAENYDRSYYPWGIPRQFSAVLG MLBr_01899|M.leprae_Br4923 VVDNVVRVTKITGSPLYRMPEEQVRTNAAEIYDRSFYPLGVSRQFSAILG MSMEG_1352|M.smegmatis_MC2_155 VLDNAVRLSRLNGSPAYPRSEEEIRAEAAELYDRAYYPAGIARHFAAILG TH_1861|M.thermoresistible__bu VIENAVKVGRLNGSPAYPVPDEQLRADAATAFDRSYHPVGVARQFDAILG MAB_3880|M.abscessus_ATCC_1997 IIANSVQVGRIIGSPKYRQSQSKSYLHAAEYYDRSYYPKGFSRQFAAIMG :: * *:: :: **. * . . .* :** ::* *. ::* *::* Mflv_5112|M.gilvum_PYR-GCK SGSLRRYDRQITAPTVVIHGRADKLMRPSGGRAIARAIPGARLVLFDGMG Mvan_1240|M.vanbaalenii_PYR-1 SGSLRRYDRQITAPTVVIHGTADKLMRPSGGRAIARAIPRARLVLFDGMG Mb0665c|M.bovis_AF2122/97 SGSLLRYDRRIVAPTVVIHGRADKLMRPFGGRAVARAINGARLVLIDGMG Rv0646c|M.tuberculosis_H37Rv SGSLLRYDRRIVAPTVVIHGRADKLMRPFGGRAVARAINGARLVLIDGMG MAV_4515|M.avium_104 SGSLRRYNRRTTAPTVVIHGRADKLMRPFGGRAVAGAIDGARLVLFDGMG MMAR_0981|M.marinum_M SGSLLGYNRRTVAPTVVIHGRADKLMRPFGGRAVAKAINGARMVEFDGMG MUL_0733|M.ulcerans_Agy99 SGSLLGYNRRTVAPTVVIHGRADKLMRPFGGRAVAKAINGARMVEFDGMG MLBr_01899|M.leprae_Br4923 SGSLLHYNQRIIAPTVVIHGRADKLVRPSSGRAVARAITGARLVLFDGMG MSMEG_1352|M.smegmatis_MC2_155 SGSLRHHNERVTAPTVVIHGRADRLMPPSGGRAIANAIRGARMVLIDGMG TH_1861|M.thermoresistible__bu SGSLRRYNRRTTSPTVVIHGRADKLMRPTGGRAVARAIPGARLTLFDGMG MAB_3880|M.abscessus_ATCC_1997 TGSLAPFDNRITAPALVLHGKADKLMRPSGARAIARAIPGSRLALIDGMG :*** .:.: :*::*:** **:*: * ..**:* ** :*:. :**** Mflv_5112|M.gilvum_PYR-GCK HDLPEPLWDDIVGELKTTFAEAP------------- Mvan_1240|M.vanbaalenii_PYR-1 HELPEPLWDDIVGELKTTFAEIS------------- Mb0665c|M.bovis_AF2122/97 HDLPRQLWDRVIGELTRNFSEAG------------- Rv0646c|M.tuberculosis_H37Rv HDLPRQLWDRVIGELTRNFSEAG------------- MAV_4515|M.avium_104 HDLPQQLWDQVIGVLANNFAKAS------------- MMAR_0981|M.marinum_M HDLPRQLWDQVIGVLTSNFEQAK------------- MUL_0733|M.ulcerans_Agy99 HDLPRQLWDQVIGVLTSNFEQAE------------- MLBr_01899|M.leprae_Br4923 HDLPQQLWDQAVGVLMSNFAKAS------------- MSMEG_1352|M.smegmatis_MC2_155 HELPEPVWDEVIGELKTNFAVVG------------- TH_1861|M.thermoresistible__bu HDLPEPLWDEIVAELDKNITAGR------------- MAB_3880|M.abscessus_ATCC_1997 HDLPEPLWNHIITKLTENFARSEPAAETPESEAAGR *:**. :*: : * .: