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M. bovis AF2122 / 97 Mb0665c (lipG)

annotation: lipase/esterase LipG
coordinates: 741470 - 742375
length: 301

VDIRSGTAVSGDVKLYYEDMGDLDHPPVLLIMGLGAQMLLWRTDFCARLVAKGLRVIRYDNRDVGLSTKT
ERHRPGQPLATRLVRSWLGLPSQAAYTLEDMAADAAALLDHLDVKHAHVVGASMGGMIAQIFAARFAQRT
KTLAVIFSSNNHRFLPPPAPRALLALLTGPPPDSPRDVIVDNAVRVSKIIGSPAYPIPEDQVRAEAAESY
DRNFHPWGIAQQFSAILGSGSLLRYDRRIVAPTVVIHGRADKLMRPFGGRAVARAINGARLVLIDGMGHD
LPRQLWDRVIGELTRNFSEAG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0665clipG-100% (301)lipase/esterase LipG
M. bovis AF2122 / 97Mb0569bpoC3e-1226.62% (278) peroxidase BpoC
M. bovis AF2122 / 97Mb1935clipJ4e-0725.09% (287) lignin peroxidase LIPJ

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_5112-1e-11468.00% (300) alpha/beta hydrolase fold
M. tuberculosis H37RvRv0646clipG1e-173100.00% (301) lipase/esterase LipG
M. leprae Br4923MLBr_01899lipG1e-12571.62% (303) putative hydrolase
M. abscessus ATCC 19977MAB_3880-3e-9054.15% (301) lipase/esterase LipG
M. marinum MMMAR_0981lipG11e-12875.60% (291) lipase/esterase LipG1
M. avium 104MAV_4515-1e-13677.67% (300) hydrolase, alpha/beta fold family protein
M. smegmatis MC2 155MSMEG_1352-1e-11164.90% (302) hydrolase, alpha/beta fold family protein
M. thermoresistible (build 8)TH_1861lipG1e-11464.90% (302) PROBABLE LIPASE/ESTERASE LIPG
M. ulcerans Agy99MUL_0733lipG11e-12875.26% (291) lipase/esterase LipG1
M. vanbaalenii PYR-1Mvan_1240-1e-11165.89% (299) alpha/beta hydrolase fold

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5112|M.gilvum_PYR-GCK          -----MQVRTGTARS-------------GELEIHYEDMGDPNDPAVLLIM
Mvan_1240|M.vanbaalenii_PYR-1       -----MQIRSGTAKS-------------GDLDIFYEDMGDPNDPAVLLIM
Mb0665c|M.bovis_AF2122/97           -----MDIRSGTAVS-------------GDVKLYYEDMGDLDHPPVLLIM
Rv0646c|M.tuberculosis_H37Rv        -----MDIRSGTAVS-------------GDVKLYYEDMGDLDHPPVLLIM
MAV_4515|M.avium_104                ----MVQVRTGHAIS-------------GDLKLYYEDMGDIDDPPVLLIM
MMAR_0981|M.marinum_M               -----MEIRTGYAQSGVGSGATSERQPAGDLKLYYEDMGDINAPPVLLIM
MUL_0733|M.ulcerans_Agy99           -----MEIRTGYAQSGVGSGATSERQPAGDLKLYYEDMGDINAPPVLLIM
MLBr_01899|M.leprae_Br4923          -----MEVRSGYATS-------------GDLKLYYEDMGNVDDPPVLLIM
MSMEG_1352|M.smegmatis_MC2_155      -----MQTRTGLARAG---------DADHPIDLFYEDMGDPGDPAVLLIM
TH_1861|M.thermoresistible__bu      -----MQIRTGFANVD---------GSPEPVDLYYEDLGDPADPPVLLIM
MAB_3880|M.abscessus_ATCC_1997      MSTTAREISEMTASTAT----------VGDIELCYEEFGNPADPAVLLIM
                                          :     *                 :.: **::*:   *.*****

Mflv_5112|M.gilvum_PYR-GCK          GLGAQLLLWRKGFCEKLINQGLRVIRFDNRDVGLSSKLT---GHHAGAPL
Mvan_1240|M.vanbaalenii_PYR-1       GLGAQLLLWRNGFCEKLINQGLRVIRFDNRDVGLSSKLH---HHRSGAPL
Mb0665c|M.bovis_AF2122/97           GLGAQMLLWRTDFCARLVAKGLRVIRYDNRDVGLSTKTE---RHRPGQPL
Rv0646c|M.tuberculosis_H37Rv        GLGAQMLLWRTDFCARLVAKGLRVIRYDNRDVGLSTKTE---RHRPGQPL
MAV_4515|M.avium_104                GLGAQLLLWRTAFCEKLVGRGLRVIRYDNRDVGLSSKTE---HRSSGQPL
MMAR_0981|M.marinum_M               GLGAQLLLWRTGFCQKLVDQGLRVIRYDNRDVGLSTKME---QPSARQPL
MUL_0733|M.ulcerans_Agy99           GLGAQLLLWRTGFCQKPVDQGLRVIRYDNRDVGLSTKME---QPSARQPL
MLBr_01899|M.leprae_Br4923          GLGAQLVLWRTAFCEKLVAQGLRVVRYDNRDVGLSSRTDSTEQPCPSQPL
MSMEG_1352|M.smegmatis_MC2_155      GLGAQMLMWRTEFCEKLVDQGLRVIRFDNRDVGLSTKLS---GQRVDSPL
TH_1861|M.thermoresistible__bu      GLGAQLILWRDGFCRKLVERGLRVIRFDNRDVGLSSKLD---GRRERTPL
MAB_3880|M.abscessus_ATCC_1997      GIGAQMVFWRPEFCQQLADQGYRVIRFDNRDCGLSTKLDG--VRAGGGSL
                                    *:***:::**  ** :   :* **:*:**** ***::           .*

Mflv_5112|M.gilvum_PYR-GCK          LPRMARSLAGLPSP-AAYTLEDMADDAAALLDHLDIDRAHVVGGSMGGMI
Mvan_1240|M.vanbaalenii_PYR-1       LPRMARSFVGRPSP-AAYTLEDMADDAAALLDHLGIDTAHVVGGSMGGMI
Mb0665c|M.bovis_AF2122/97           ATRLVRSWLGLPSQ-AAYTLEDMAADAAALLDHLDVKHAHVVGASMGGMI
Rv0646c|M.tuberculosis_H37Rv        ATRLVRSWLGLPSQ-AAYTLEDMAADAAALLDHLDVKHAHVVGASMGGMI
MAV_4515|M.avium_104                VTRLLRSWLGLPSQ-SAYRLEDMADDAAAVLDHLGIDDAHIVGASMGGMI
MMAR_0981|M.marinum_M               MPQLIRSWLGRRSQ-TPYTLEDMADDAAALLDHLDIERAHIVGASMGGMI
MUL_0733|M.ulcerans_Agy99           MPQLIRSWLGRRSQ-TPYTLEDMADDAAALLDHLDIERAHIVGASMGGMI
MLBr_01899|M.leprae_Br4923          TARLIRFWLGQRNA-CAYTLEDMTDDAVALLDHLSIERAHIVGASMGGMI
MSMEG_1352|M.smegmatis_MC2_155      ALRMARSFLGKRSP-AVYTLEDMADDAAALLDHLEIDRAHIVGGSMGGMI
TH_1861|M.thermoresistible__bu      PWRMLRSFAGLPSP-AVYTLEDMADDAAGLLDHLQIDAAHIVGASMGGMV
MAB_3880|M.abscessus_ATCC_1997      IPSMAKFLAGVKITGTAYTLVDMAGDAAGLLDHLGIEQAHIVGASMGGMI
                                       : :   *       * * **: **..:**** :. **:**.*****:

Mflv_5112|M.gilvum_PYR-GCK          AQVFAARHHPRTKTLGVIFSSNNQAALPPPGPRQLAAILQRP-KGSSRDE
Mvan_1240|M.vanbaalenii_PYR-1       AQVFAARHRARTGALGVIFSSNNQAALPPPGPRQLAAILQRP-KGSDREA
Mb0665c|M.bovis_AF2122/97           AQIFAARFAQRTKTLAVIFSSNNHRFLPPPAPRALLALLTGPPPDSPRDV
Rv0646c|M.tuberculosis_H37Rv        AQIFAARFAQRTKTLAVIFSSNNHRFLPPPAPRALLALLTGPPPDSPRDV
MAV_4515|M.avium_104                AQIFAARFRQRTKTLAVIFSSNNSALLPPPAPRALLALLKGPPPDSPREV
MMAR_0981|M.marinum_M               AQIFAARFAERTNSLAVIFSSNNRPFLPPPAPRALLAVLNGPPPGSPREV
MUL_0733|M.ulcerans_Agy99           AQIFAARFAERTNSLAVIFSSNNRPFLPPPAPRALLAVLNGPPPGSPREV
MLBr_01899|M.leprae_Br4923          AQIFAARFPTRTRSLAVFFSSNNRPFLPPPAPRALLALLTGPPTGSRRDV
MSMEG_1352|M.smegmatis_MC2_155      AQVFASQHAARTETLGVIFSSNNQALLPPPGIRQLLSLITGPPADASRDA
TH_1861|M.thermoresistible__bu      AQVFAGRHAHRTRSLGVIFSSNNRPFLPPPGPRQLLSIITGPAPDAPRDE
MAB_3880|M.abscessus_ATCC_1997      AQVFAAEHPDRTATVSIIMSSNNQPFLPPPGPRQLMALLKPPPEGASREQ
                                    **:**...  ** ::.:::****   ****. * * :::  *  .: *: 

Mflv_5112|M.gilvum_PYR-GCK          IVDNAVRVSRIIGSPGYPAPLDRLRTDAIEGFDRSYYPAGVGRHFAAILG
Mvan_1240|M.vanbaalenii_PYR-1       IIENAVRVSRIIGSPGYPAAEERLRADAIEGYDRSYYPAGVGRHFAAILG
Mb0665c|M.bovis_AF2122/97           IVDNAVRVSKIIGSPAYPIPEDQVRAEAAESYDRNFHPWGIAQQFSAILG
Rv0646c|M.tuberculosis_H37Rv        IVDNAVRVSKIIGSPAYPIPEDQVRAEAAESYDRNFHPWGIAQQFSAILG
MAV_4515|M.avium_104                IIDNAVRVGRIIGSTRYRVPEEQARAEAAEGYDRNYYPQGVARHFSAVLG
MMAR_0981|M.marinum_M               IIDNVVRVTRITGSPGYQPTEEWIRADAAENYDRSYYPWGIPRQFSAVLG
MUL_0733|M.ulcerans_Agy99           IIDNVVRVTRITGSPGYQPTEEWIRADAAENYDRSYYPWGIPRQFSAVLG
MLBr_01899|M.leprae_Br4923          VVDNVVRVTKITGSPLYRMPEEQVRTNAAEIYDRSFYPLGVSRQFSAILG
MSMEG_1352|M.smegmatis_MC2_155      VLDNAVRLSRLNGSPAYPRSEEEIRAEAAELYDRAYYPAGIARHFAAILG
TH_1861|M.thermoresistible__bu      VIENAVKVGRLNGSPAYPVPDEQLRADAATAFDRSYHPVGVARQFDAILG
MAB_3880|M.abscessus_ATCC_1997      IIANSVQVGRIIGSPKYRQSQSKSYLHAAEYYDRSYYPKGFSRQFAAIMG
                                    :: * *:: :: **. *  . .    .*   :** ::* *. ::* *::*

Mflv_5112|M.gilvum_PYR-GCK          SGSLRRYDRQITAPTVVIHGRADKLMRPSGGRAIARAIPGARLVLFDGMG
Mvan_1240|M.vanbaalenii_PYR-1       SGSLRRYDRQITAPTVVIHGTADKLMRPSGGRAIARAIPRARLVLFDGMG
Mb0665c|M.bovis_AF2122/97           SGSLLRYDRRIVAPTVVIHGRADKLMRPFGGRAVARAINGARLVLIDGMG
Rv0646c|M.tuberculosis_H37Rv        SGSLLRYDRRIVAPTVVIHGRADKLMRPFGGRAVARAINGARLVLIDGMG
MAV_4515|M.avium_104                SGSLRRYNRRTTAPTVVIHGRADKLMRPFGGRAVAGAIDGARLVLFDGMG
MMAR_0981|M.marinum_M               SGSLLGYNRRTVAPTVVIHGRADKLMRPFGGRAVAKAINGARMVEFDGMG
MUL_0733|M.ulcerans_Agy99           SGSLLGYNRRTVAPTVVIHGRADKLMRPFGGRAVAKAINGARMVEFDGMG
MLBr_01899|M.leprae_Br4923          SGSLLHYNQRIIAPTVVIHGRADKLVRPSSGRAVARAITGARLVLFDGMG
MSMEG_1352|M.smegmatis_MC2_155      SGSLRHHNERVTAPTVVIHGRADRLMPPSGGRAIANAIRGARMVLIDGMG
TH_1861|M.thermoresistible__bu      SGSLRRYNRRTTSPTVVIHGRADKLMRPTGGRAVARAIPGARLTLFDGMG
MAB_3880|M.abscessus_ATCC_1997      TGSLAPFDNRITAPALVLHGKADKLMRPSGARAIARAIPGSRLALIDGMG
                                    :***  .:.:  :*::*:** **:*: * ..**:* **  :*:. :****

Mflv_5112|M.gilvum_PYR-GCK          HDLPEPLWDDIVGELKTTFAEAP-------------
Mvan_1240|M.vanbaalenii_PYR-1       HELPEPLWDDIVGELKTTFAEIS-------------
Mb0665c|M.bovis_AF2122/97           HDLPRQLWDRVIGELTRNFSEAG-------------
Rv0646c|M.tuberculosis_H37Rv        HDLPRQLWDRVIGELTRNFSEAG-------------
MAV_4515|M.avium_104                HDLPQQLWDQVIGVLANNFAKAS-------------
MMAR_0981|M.marinum_M               HDLPRQLWDQVIGVLTSNFEQAK-------------
MUL_0733|M.ulcerans_Agy99           HDLPRQLWDQVIGVLTSNFEQAE-------------
MLBr_01899|M.leprae_Br4923          HDLPQQLWDQAVGVLMSNFAKAS-------------
MSMEG_1352|M.smegmatis_MC2_155      HELPEPVWDEVIGELKTNFAVVG-------------
TH_1861|M.thermoresistible__bu      HDLPEPLWDEIVAELDKNITAGR-------------
MAB_3880|M.abscessus_ATCC_1997      HDLPEPLWNHIITKLTENFARSEPAAETPESEAAGR
                                    *:**. :*:  :  *  .: