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TMQHNDIQLAVIDMAGTTVADDGLVVEAFEVAAEAGGLPAAGPDRDDARQYVLDTMGQSKITVFRALFGD EATAQRANASFEDAYAALIAAGRAEPIPGAAESLSRLRDAGIKVALTTGFSPDTQGKLISALGWHDIADV VLAPGDGVRGRPYPDLILTALLRTGADRVQAVAALGDTANDVESALRAGCAIAAGTLTGAHDERQLVAAG ATHVVASVTDFADLLLRG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0053 | - | - | 100% (229) | hydrolase |
| M. vanbaalenii PYR-1 | Mvan_1937 | - | 9e-13 | 31.36% (220) | HAD family hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4417 | - | 8e-12 | 28.83% (222) | HAD family hydrolase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1500 | - | 2e-74 | 62.90% (221) | putative haloacid dehalogenase-like hydrolase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_0437 | - | 3e-09 | 29.07% (172) | hydrolase |
| M. smegmatis MC2 155 | MSMEG_4401 | - | 1e-27 | 34.68% (222) | phosphonoacetaldehyde hydrolase |
| M. thermoresistible (build 8) | TH_3516 | - | 1e-73 | 64.49% (214) | PUTATIVE HAD-superfamily hydrolase, subfamily IA, variant 3 |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_1500|M.abscessus_ATCC_1997 ----------MSDIPIRLAVLDMAGTTVADGGLVLQAFETAATAGGIEQD
TH_3516|M.thermoresistible__bu ----------------------MAGTTVTDDGLVLRAFDAAATAVGMAES
Mvan_0053|M.vanbaalenii_PYR-1 --------MTMQHNDIQLAVIDMAGTTVADDGLVVEAFEVAAEAGGLPAA
MSMEG_4401|M.smegmatis_MC2_155 MNISEGTRMSSTVRRPELVVLDIAGTTVDEGSAVYRVLEQTVVAHGGTPS
Mflv_4417|M.gilvum_PYR-GCK ---------MSTQSVSPAVLFDIDGTLVDSNYLHVHAWMRAFDDENLPVS
MAV_0437|M.avium_104 ---------------------------MDSNYLHVHSWQRAFDDEDIAVA
: .. . : .
MAB_1500|M.abscessus_ATCC_1997 GPERERARQYVIETMGQSKIAVFRYLLG--DEDKAQHANRTFEDAYDALI
TH_3516|M.thermoresistible__bu GAEREAARRYVVDTMGRSKIEVFRALLA--DEDRAQRANAAFESAYDRFI
Mvan_0053|M.vanbaalenii_PYR-1 GPDRDDARQYVLDTMGQSKITVFRALFG--DEATAQRANASFEDAYAALI
MSMEG_4401|M.smegmatis_MC2_155 EAD-------IAKWHGAAKHEALRALLAPADDAALQVIVEDFRARLKAAY
Mflv_4417|M.gilvum_PYR-GCK AWR-------IHRCIGMDGTTLVRTLSG----DAGQGVLDRLKDAHSRYY
MAV_0437|M.avium_104 SWQ-------IHRCIGMDGSTLVRTLSG----DAPDDVGERLRDRHSRYY
: * .* * . : :.
MAB_1500|M.abscessus_ATCC_1997 SDGR--VTPIDGAVQAISRLRDAGVKVALTTGFSASTKEKLLAALAWT--
TH_3516|M.thermoresistible__bu AEG---VAPVPGAAEAIGELRSAGVKVALTTGFSPATQARILDALGWT--
Mvan_0053|M.vanbaalenii_PYR-1 AAGR--AEPIPGAAESLSRLRDAGIKVALTTGFSPDTQGKLISALGWH--
MSMEG_4401|M.smegmatis_MC2_155 AEHP--PVPLPGVPDAIRDLRASGIKVALNTGFDRDIVDALLASLGWDGD
Mflv_4417|M.gilvum_PYR-GCK KENSSLLAPLPGARDLLRRVAATGLQVVLATSAPDDELTLLREVLDCD--
MAV_0437|M.avium_104 RELTPLLKPLPGARAMLRRVADLGLQVVLASSAPEDELEILRKVLDCD--
*: *. : : *::*.* :. : *
MAB_1500|M.abscessus_ATCC_1997 DIADLTLAPSEAGRGRPFPDLILASLLRLKVNDVREVAVLGDTASDILAG
TH_3516|M.thermoresistible__bu DIADLTLAPDTGVRGRPYPDLVLTAVLRVGIDDVRHVAVAGDTASDIETG
Mvan_0053|M.vanbaalenii_PYR-1 DIADVVLAPGDGVRGRPYPDLILTALLRTGADRVQAVAALGDTANDVESA
MSMEG_4401|M.smegmatis_MC2_155 SVVDTVVCGSDVAAGRPAPYMIYRAMEHSGVQDISRVLVAGDTPRDLQAG
Mflv_4417|M.gilvum_PYR-GCK DVVAAVTSSADVDTAKPKPDIVQVALDRAGVG-AQDAVFVGDAVWDCEAA
MAV_0437|M.avium_104 DVIAATTSSRDVDTAKPEPGIVRVALDRAGVR-AEEAVFVGDAVWDAHAA
.: . . .:* * :: :: : . **: * :.
MAB_1500|M.abscessus_ATCC_1997 RRAGAQIVAGTLTGAHDAAQLGTAQPTHIVHSVVEFPDIILRRI------
TH_3516|M.thermoresistible__bu LRAGASIATGVLTGAHDEQTLRAAGATHVLESVADLPRLVLR--------
Mvan_0053|M.vanbaalenii_PYR-1 LRAGCAIAAGTLTGAHDERQLVAAGATHVVASVTDFADLLLRG-------
MSMEG_4401|M.smegmatis_MC2_155 INAGAGYVVGVLSGASDEAELSAHPHTHLLSSVADLPELFGVTRTAATAS
Mflv_4417|M.gilvum_PYR-GCK GRAGVTSIG-LLSGGVSRGELREAGAAGVFEDAGDLLAKLDSTVIGDLAA
MAV_0437|M.avium_104 RGAGLACIG-LCSGGIARDELRAAGADPVFADPQDLLDHLESTRIAALAR
** :*. * :. . :: .
MAB_1500|M.abscessus_ATCC_1997 ------
TH_3516|M.thermoresistible__bu ------
Mvan_0053|M.vanbaalenii_PYR-1 ------
MSMEG_4401|M.smegmatis_MC2_155 ------
Mflv_4417|M.gilvum_PYR-GCK RVSDPR
MAV_0437|M.avium_104 GG----