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NISEGTRMSSTVRRPELVVLDIAGTTVDEGSAVYRVLEQTVVAHGGTPSEADIAKWHGAAKHEALRALLA PADDAALQVIVEDFRARLKAAYAEHPPVPLPGVPDAIRDLRASGIKVALNTGFDRDIVDALLASLGWDGD SVVDTVVCGSDVAAGRPAPYMIYRAMEHSGVQDISRVLVAGDTPRDLQAGINAGAGYVVGVLSGASDEAE LSAHPHTHLLSSVADLPELFGVTRTAATAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4401 | - | - | 100% (241) | phosphonoacetaldehyde hydrolase |
| M. smegmatis MC2 155 | MSMEG_4308 | - | 4e-07 | 24.12% (228) | 5'-nucleotidase |
| M. smegmatis MC2 155 | MSMEG_4183 | - | 9e-06 | 34.34% (99) | phosphoglycolate phosphatase, chromosomal |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2257 | - | 1e-05 | 22.71% (229) | hypothetical protein Mb2257 |
| M. gilvum PYR-GCK | Mflv_2889 | - | 5e-09 | 24.79% (234) | HAD family hydrolase |
| M. tuberculosis H37Rv | Rv2232 | - | 1e-05 | 22.71% (229) | hypothetical protein Rv2232 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1500 | - | 5e-27 | 35.45% (220) | putative haloacid dehalogenase-like hydrolase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_0437 | - | 6e-08 | 30.00% (160) | hydrolase |
| M. thermoresistible (build 8) | TH_3516 | - | 6e-30 | 37.16% (218) | PUTATIVE HAD-superfamily hydrolase, subfamily IA, variant 3 |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0053 | - | 1e-27 | 34.68% (222) | hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3516|M.thermoresistible__bu --------------------------------------------------
Mvan_0053|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1500|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4401|M.smegmatis_MC2_155 --------------------------------------------------
Mb2257|M.bovis_AF2122/97 MSSPRERRPASQAPRLSRRPPAHQTSRSSPDTTAPTGSGLSNRFVNDNGI
Rv2232|M.tuberculosis_H37Rv MSSPRERRPASQAPRLSRRPPAHQTSRSSPDTTAPTGSGLSNRFVNDNGI
Mflv_2889|M.gilvum_PYR-GCK --------------------------------------------------
MAV_0437|M.avium_104 --------------------------------------------------
TH_3516|M.thermoresistible__bu -----------------------------------MAGTTVTDDGLVLRA
Mvan_0053|M.vanbaalenii_PYR-1 ---------------------MTMQHNDIQLAVIDMAGTTVADDGLVVEA
MAB_1500|M.abscessus_ATCC_1997 -----------------------MSDIPIRLAVLDMAGTTVADGGLVLQA
MSMEG_4401|M.smegmatis_MC2_155 -------------MNISEGTRMSSTVRRPELVVLDIAGTTVDEGSAVYRV
Mb2257|M.bovis_AF2122/97 VTDTTASGTNCPPPPRAAARRASSPGESPQLVIFDLDGTLTDSARGIVSS
Rv2232|M.tuberculosis_H37Rv VTDTTASGTNCPPPPRAAARRASSPGESPQLVIFDLDGTLTDSARGIVSS
Mflv_2889|M.gilvum_PYR-GCK MTDMLDG-----------TRRVAPVGRG-DLVLFDLDGTLTDSAEGIVAS
MAV_0437|M.avium_104 ----------------------------------------MDSNYLHVHS
.
TH_3516|M.thermoresistible__bu FDAAATAVGMAESGAEREAARRYVVDTMGRSKIEVFRALLA--DEDRAQR
Mvan_0053|M.vanbaalenii_PYR-1 FEVAAEAGGLPAAGPDRDDARQYVLDTMGQSKITVFRALFG--DEATAQR
MAB_1500|M.abscessus_ATCC_1997 FETAATAGGIEQDGPERERARQYVIETMGQSKIAVFRYLLG--DEDKAQH
MSMEG_4401|M.smegmatis_MC2_155 LEQTVVAHGGTPSEAD-------IAKWHGAAKHEALRALLAPADDAALQV
Mb2257|M.bovis_AF2122/97 FRHALNHIGAPVPEGD------LATHIVGPPMHETLRAMGLG---ESAEE
Rv2232|M.tuberculosis_H37Rv FRHALNHIGAPVPEGD------LATHIVGPPMHETLRAMGLG---ESAEE
Mflv_2889|M.gilvum_PYR-GCK FRHALQSVGAAVPDGD------LVSKIVGPPMPLTFQRMGLG---DLVDD
MAV_0437|M.avium_104 WQRAFDDEDIAVASWQ-------IHRCIGMDGSTLVRTLSGDAPDDVGER
: . : * .: : :
TH_3516|M.thermoresistible__bu ANAAFESAYDRFIAEG-VAPVPGAAEAIGELRSAGVKVALTTGFSPATQA
Mvan_0053|M.vanbaalenii_PYR-1 ANASFEDAYAALIAAGRAEPIPGAAESLSRLRDAGIKVALTTGFSPDTQG
MAB_1500|M.abscessus_ATCC_1997 ANRTFEDAYDALISDGRVTPIDGAVQAISRLRDAGVKVALTTGFSASTKE
MSMEG_4401|M.smegmatis_MC2_155 IVEDFRARLKAAYAEHPPVPLPGVPDAIRDLRASGIKVALNTGFDRDIVD
Mb2257|M.bovis_AF2122/97 AIVAYRADYSAR-GWAMNSLFDGIGPLLADLRTAGVRLAVATSKAEPTAR
Rv2232|M.tuberculosis_H37Rv AIVAYRADYSAR-GWAMNSLFDGIGPLLADLRTAGVRLAVATSKAEPTAR
Mflv_2889|M.gilvum_PYR-GCK AIAAYRADYTTR-GWSMNRPFDGIPALLADLQAAGVRMAVATSKAETTAQ
MAV_0437|M.avium_104 LRDRHSRYYREL--TPLLKPLPGARAMLRRVADLGLQVVLASSAPEDELE
. . * : : *:::.: :.
TH_3516|M.thermoresistible__bu RILDALGWT--DIADLTLAPDTGVRGRPYPDLVLTAVLRVGIDDVRHVAV
Mvan_0053|M.vanbaalenii_PYR-1 KLISALGWH--DIADVVLAPGDGVRGRPYPDLILTALLRTGADRVQAVAA
MAB_1500|M.abscessus_ATCC_1997 KLLAALAWT--DIADLTLAPSEAGRGRPFPDLILASLLRLKVNDVREVAV
MSMEG_4401|M.smegmatis_MC2_155 ALLASLGWDGDSVVDTVVCGSDVAAGRPAPYMIYRAMEHSGVQDISRVLV
Mb2257|M.bovis_AF2122/97 RILRHFGIE--QHFEVIAGASTDGSRGSKVDVLAHALAQLRP-LPERLVM
Rv2232|M.tuberculosis_H37Rv RILRHFGIE--QHFEVIAGASTDGSRGSKVDVLAHALAQLRP-LPERLVM
Mflv_2889|M.gilvum_PYR-GCK RILAHFGLD--GHFEVIAGASNDGTRAAKSDVVAHALAQLAP-VPDNVVM
MAV_0437|M.avium_104 ILRKVLDCD--DVIAATTSSRDVDTAKPEPGIVRVALDRAGV-RAEEAVF
: : . :: :: :
TH_3516|M.thermoresistible__bu AGDTASDIETGLRAGAS-IATGVLTGAHDEQTLRAAGATHVLESVADLPR
Mvan_0053|M.vanbaalenii_PYR-1 LGDTANDVESALRAGCA-IAAGTLTGAHDERQLVAAGATHVVASVTDFAD
MAB_1500|M.abscessus_ATCC_1997 LGDTASDILAGRRAGAQ-IVAGTLTGAHDAAQLGTAQPTHIVHSVVEFPD
MSMEG_4401|M.smegmatis_MC2_155 AGDTPRDLQAGINAGAG-YVVGVLSGASDEAELSAHPHTHLLSSVADLPE
Mb2257|M.bovis_AF2122/97 VGDRSHDVDGAAAHGIDTVVVGWGYGRADFIDKTSTTVVTHAATIDELRE
Rv2232|M.tuberculosis_H37Rv VGDRSHDVDGAAAHGIDTVVVGWGYGRADFIDKTSTTVVTHAATIDELRE
Mflv_2889|M.gilvum_PYR-GCK IGDRSHDVEGAAVHGIATIVVGWGYGRTDFAGRESG-ALAHVTDVDDLRE
MAV_0437|M.avium_104 VGDAVWDAHAARGAGLA--CIGLCSGGIARDELRAAGADPVFADPQDLLD
** * . * * * : ::
TH_3516|M.thermoresistible__bu LVLR----------
Mvan_0053|M.vanbaalenii_PYR-1 LLLRG---------
MAB_1500|M.abscessus_ATCC_1997 IILRRI--------
MSMEG_4401|M.smegmatis_MC2_155 LFGVTRTAATAS--
Mb2257|M.bovis_AF2122/97 ALGV----------
Rv2232|M.tuberculosis_H37Rv ALGV----------
Mflv_2889|M.gilvum_PYR-GCK VLGV----------
MAV_0437|M.avium_104 HLESTRIAALARGG
.