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MAVTPESAKVVVGVDDLSSSQPALEWAAAEAGRRGAPLVILYAATLPIGAWPVVPVPTGFLDWQRQIGQE ILADARQIAEKLTAGAIPVTAEFAVATPTAALVEESRTAGMVVVGSRGRGGFARKVLGSTSMGLVHRAHC PVVVVRDDGSAPASDAPVLLGFDGSASAAPAVEIAFQEASQRGVGLVAVHAWWSPGAFEMPGFDWEEVRP DVEREASRQLSDWQRRYPGVPVELVVVRDQPARRLVERSGAAQLLVVGSHGYGAVTGSLLGSVSGAVVQA ATTPVMVVRPGDS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4978 | - | - | 100% (293) | UspA domain-containing protein |
| M. gilvum PYR-GCK | Mflv_4382 | - | 1e-65 | 46.78% (295) | UspA domain-containing protein |
| M. gilvum PYR-GCK | Mflv_4999 | - | 9e-52 | 43.21% (287) | UspA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2028c | - | 2e-65 | 45.77% (284) | hypothetical protein Mb2028c |
| M. tuberculosis H37Rv | Rv2005c | - | 2e-65 | 45.77% (284) | hypothetical protein Rv2005c |
| M. leprae Br4923 | MLBr_01390 | - | 6e-05 | 32.39% (142) | hypothetical protein MLBr_01390 |
| M. abscessus ATCC 19977 | MAB_2489 | - | 7e-40 | 36.05% (294) | hypothetical protein MAB_2489 |
| M. marinum M | MMAR_3477 | - | 3e-65 | 44.60% (287) | hypothetical protein MMAR_3477 |
| M. avium 104 | MAV_2507 | - | 9e-64 | 46.46% (297) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_3945 | - | 2e-56 | 43.38% (272) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_4471 | - | 2e-63 | 46.08% (293) | PUTATIVE putative universal stress protein family protein |
| M. ulcerans Agy99 | MUL_2234 | - | 2e-64 | 44.72% (284) | hypothetical protein MUL_2234 |
| M. vanbaalenii PYR-1 | Mvan_1425 | - | 1e-130 | 80.00% (285) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2028c|M.bovis_AF2122/97 MSKPRKQ----HGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVN-
Rv2005c|M.tuberculosis_H37Rv MSKPRKQ----HGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVN-
MUL_2234|M.ulcerans_Agy99 MSTLGKR----LGVVVGVDGSPASNAAVCWAARDAAMRNLPLTVVHVVN-
MMAR_3477|M.marinum_M MSAPMKH----LGIVVGVDGSAASYAAVSWAARDATLRHVPLTLVHMVN-
MAV_2507|M.avium_104 MAASSKR----CGVLVGVDGSPASNFAVCWAARDAAMRNVPLTLVHMVN-
TH_4471|M.thermoresistible__bu MAIPAIQ----DSIVAGVDGSPSSAAAVEWAARNAALRDRPLVLVHVVPS
Mflv_4978|M.gilvum_PYR-GCK MAVTPES----AKVVVGVDDLSSSQPALEWAAAEAGRRGAPLVILYAAT-
Mvan_1425|M.vanbaalenii_PYR-1 MAAAAEFGNEIGNVVVGVDDSPSSQPALEWAAAEAKLRNIPLVILYATT-
MSMEG_3945|M.smegmatis_MC2_155 ---------------------------MEWAAKEAVLHKVPLRIVHVMQ-
MAB_2489|M.abscessus_ATCC_1997 MTTSTPN----SHILVGVDGSTSALHALTWAGAEAQRRNLPLTLVHVID-
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Mb2028c|M.bovis_AF2122/97 --ADVATWPPMPYPETWGVWQEDEGRQIVANAVKLAKEAVGADRKLSVKS
Rv2005c|M.tuberculosis_H37Rv --ADVATWPPMPYPETWGVWQEDEGRQIVANAVKLAKEAVGADRKLSVKS
MUL_2234|M.ulcerans_Agy99 --TDVATWPPMPYPDTWAVWQEDEGRKVIAGAVKIAEDSVAGDRELTIKS
MMAR_3477|M.marinum_M --QAVPMWPEMPMMTSMSAWQEEDGRQVLEQAGKIAQEVTQQGRDTQIKS
MAV_2507|M.avium_104 --AAT-VWPQVPMAAEAVAWQEDDGRRVLQEAVKIAEDATRNGRNLAITT
TH_4471|M.thermoresistible__bu PMVTTAPWPQLPLPDDAFRVMQEEGERLLAQARAAAEQAGAG----EVRT
Mflv_4978|M.gilvum_PYR-GCK LPIG--AWPVVPVPTGFLDWQRQIGQEILADARQIAEKLTAGAIPVTAEF
Mvan_1425|M.vanbaalenii_PYR-1 LPIG--AWPVVPVPTGFLDWQRQIGQDILKDAGQIAKELTGGAVPVTAEF
MSMEG_3945|M.smegmatis_MC2_155 WPPGSATWSEIPAPTTLADQLKRNAEQLLKEARKVAEDVVGGAVEIHVDD
MAB_2489|M.abscessus_ATCC_1997 -HSSLGQGYNLGASASFFQHLETDGAEFLSQAKDHVYALHPN---VEVST
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Mb2028c|M.bovis_AF2122/97 ELVFSTPVPTMVEISNEAEMVVLGSSGRGALARGLLGSVSSSLVRRAGCP
Rv2005c|M.tuberculosis_H37Rv ELVFSTPVPTMVEISNEAEMVVLGSSGRGALARGLLGSVSSSLVRRAGCP
MUL_2234|M.ulcerans_Agy99 EIVFSLPVPTMVEMSAEAELMVVGSSGHGALARVLLGSVSSSLVRRASCP
MMAR_3477|M.marinum_M ELRWSAPVPTFVELSQEADLVVVGSHGRGAVARGLLGSVSSGVVHRAHCP
MAV_2507|M.avium_104 ELWHAPPAPTLAQLSEEAELVVVGSTGRGAIGRLLLGSVSSGLVRRARCP
TH_4471|M.thermoresistible__bu AVLQAGIVGTLTELSRDADRIVVGSRGQTALGRMLLGSVSTGLVHQAECP
Mflv_4978|M.gilvum_PYR-GCK AVAT--PTAALVEESRTAGMVVVGSRGRGGFARKVLGSTSMGLVHRAHCP
Mvan_1425|M.vanbaalenii_PYR-1 AVAT--PTAALVEASHTAGMVVVGSRGQGGLLRKVLGSTSMGVIHRAHCP
MSMEG_3945|M.smegmatis_MC2_155 VVVAGSVVAALTELSESSRLLVVGCRGLGPIGRRLLGSVTAGLIRHARCP
MAB_2489|M.abscessus_ATCC_1997 VKATGRPVPVLVELSRNALMTVLGSSGLGGFTGMMAGSVSVSLTAKGHSP
MLBr_01390|M.leprae_Br4923 --------------MGAYQTVVVGTDGSDSSLRAVD--------------
*:* * :
Mb2028c|M.bovis_AF2122/97 VAVIHSDDAVIPDP---QHAPVLVGIDGSPVSELATAVAFDEASRRGVEL
Rv2005c|M.tuberculosis_H37Rv VAVIHSDDAVIPDP---QHAPVLVGIDGSPVSELATAVAFDEASRRGVEL
MUL_2234|M.ulcerans_Agy99 VAVIRDEDPMIPDP---LHAPVLVGIDGSPASELATAVAFDEASRRGVEL
MMAR_3477|M.marinum_M VAVIRDEDPEAPQPEDRDRAPVVVGIDGSSASELATAIAFDEASRRGVEL
MAV_2507|M.avium_104 VAVIHDEDPMMPYP---QRAPVLVGIDGSPASELATAIAFDEALRRGVDL
TH_4471|M.thermoresistible__bu VVIVRDGDQ---PP---GDAPVLVGIDGSPASELATEVAFEEASVRQVEL
Mflv_4978|M.gilvum_PYR-GCK VVVVRDD--GSAPA---SDAPVLLGFDGSASAAPAVEIAFQEASQRGVGL
Mvan_1425|M.vanbaalenii_PYR-1 VVVVHDE--EPAPP---GGAPVVLGFDGSPGSEAAVEIAFQEASRRGVGL
MSMEG_3945|M.smegmatis_MC2_155 VAVIHGESKASAIA---TTAPVVVGVDGSPASEKALEFAFDAASRRGAPL
MAB_2489|M.abscessus_ATCC_1997 VVVVRES----PVP---GGGPVVVGIDDSESSDGAAAWAFEEAAMRETEL
MLBr_01390|M.leprae_Br4923 ------------------RAGKIAGSDAKLIIASAYLPQHDNAR------
. : * * . * .: *
Mb2028c|M.bovis_AF2122/97 IAVHAWSDV------EVVELPGLDFSAVQQEAELSLAERLAGWQERYPDV
Rv2005c|M.tuberculosis_H37Rv IAVHAWSDV------EVVELPGLDFSAVQQEAELSLAERLAGWQERYPDV
MUL_2234|M.ulcerans_Agy99 IAVHAWSDQ------GVVELPGLNWSTMEAEARLSLAERLAGWEERYPDV
MMAR_3477|M.marinum_M KAVHAWSDL------EVVDLPGLDWSTVKGEAEETLAERLAGWQERYPDV
MAV_2507|M.avium_104 NAVHAWSDT------QVFGLPGMDWPAVRSQAERSLAERLAGWQERYPDV
TH_4471|M.thermoresistible__bu VALHGWRDT------SLFHYPGLDTESLQTQAEAVLAERLAGWQERYPDV
Mflv_4978|M.gilvum_PYR-GCK VAVHAWWSP------GAFEMPGFDWEEVRPDVEREASRQLSDWQRRYPGV
Mvan_1425|M.vanbaalenii_PYR-1 VALHSWWSP------GAFEMPGFDWEEIRPEVEQEAARQLAPWQKRYPGV
MSMEG_3945|M.smegmatis_MC2_155 LAVHAWSDA------NVAGYPGVRWDDLRVQAEESLSERLAGWQERYPDV
MAB_2489|M.abscessus_ATCC_1997 VAVHVWNNIPPGYVYAYTAWSAMDSAGEQQRQEQLLAERLAGWQEKYPDV
MLBr_01390|M.leprae_Br4923 -AFDILKDE------------SYKVTGTAPIYEILHDAKERAHAAGAKNV
*.. . . . : .*
Mb2028c|M.bovis_AF2122/97 PVSRVVVCDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLGSVSNAVLHA
Rv2005c|M.tuberculosis_H37Rv PVSRVVVCDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLGSVSNAVLHA
MUL_2234|M.ulcerans_Agy99 TVRRVVVCDEPAHQLVEMSQTVQLVVVGSHGRGGITGVLLGSVSNAVVHA
MMAR_3477|M.marinum_M TVDRVVVCDRPARQLIDQAQTAQLVVLGSHGRGGFTSMLVGSTSNAVLHA
MAV_2507|M.avium_104 TVHRMVVCDRPARQLIEQSESAQLTVVGSHGRGGLAGTLLGSVSNAVVHS
TH_4471|M.thermoresistible__bu TVRRVVVAEHPARALVQRAEEAQLVVVGSRGRSGLTGKLLGSVSTGVVHS
Mflv_4978|M.gilvum_PYR-GCK PVELVVVRDQPARRLVERSGAAQLLVVGSHGYGAVTGSLLGSVSGAVVQA
Mvan_1425|M.vanbaalenii_PYR-1 AVERVVVSDEPARRLVERSESAQLLIVGSHGYGAVTGALLGSVSGAVVQA
MSMEG_3945|M.smegmatis_MC2_155 HVRREVVLDRPDRRLLKRSEIAQLTVVGSHGRGGFAGLLLGSVSTSVAEA
MAB_2489|M.abscessus_ATCC_1997 PVRRVVAVGHPADVLLSQAAGAQLIVTGSRGRGDIAGFFLGSTSHALIHK
MLBr_01390|M.leprae_Br4923 EERPVVGAPVDALVNLAEKTNADLLVVGNVGLSTIAGRLLGSVPANVSRR
* : .:* : *. * . .:. ::**.. : .
Mb2028c|M.bovis_AF2122/97 ARVPVIVARQS--
Rv2005c|M.tuberculosis_H37Rv ARVPVIVARQS--
MUL_2234|M.ulcerans_Agy99 VRMPVIVARSS--
MMAR_3477|M.marinum_M VHTPVIVARSA--
MAV_2507|M.avium_104 VRMPVIVARPS--
TH_4471|M.thermoresistible__bu VRVPVMVARPR--
Mflv_4978|M.gilvum_PYR-GCK ATTPVMVVRPGDS
Mvan_1425|M.vanbaalenii_PYR-1 ARVPVMVVRPRTP
MSMEG_3945|M.smegmatis_MC2_155 AERPVVVVRG---
MAB_2489|M.abscessus_ATCC_1997 ASCPVLVAPRT--
MLBr_01390|M.leprae_Br4923 AKIDVLIVHTTH-
. *::.