For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AAAAEFGNEIGNVVVGVDDSPSSQPALEWAAAEAKLRNIPLVILYATTLPIGAWPVVPVPTGFLDWQRQI GQDILKDAGQIAKELTGGAVPVTAEFAVATPTAALVEASHTAGMVVVGSRGQGGLLRKVLGSTSMGVIHR AHCPVVVVHDEEPAPPGGAPVVLGFDGSPGSEAAVEIAFQEASRRGVGLVALHSWWSPGAFEMPGFDWEE IRPEVEQEAARQLAPWQKRYPGVAVERVVVSDEPARRLVERSESAQLLIVGSHGYGAVTGALLGSVSGAV VQAARVPVMVVRPRTP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1425 | - | - | 100% (297) | UspA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_1963 | - | 2e-68 | 49.48% (287) | UspA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_1415 | - | 6e-62 | 44.06% (286) | UspA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2028c | - | 3e-72 | 48.59% (284) | hypothetical protein Mb2028c |
| M. gilvum PYR-GCK | Mflv_4978 | - | 1e-130 | 80.00% (285) | UspA domain-containing protein |
| M. tuberculosis H37Rv | Rv2005c | - | 3e-72 | 48.59% (284) | hypothetical protein Rv2005c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2489 | - | 8e-41 | 37.46% (291) | hypothetical protein MAB_2489 |
| M. marinum M | MMAR_3477 | - | 6e-73 | 46.34% (287) | hypothetical protein MMAR_3477 |
| M. avium 104 | MAV_2507 | - | 9e-73 | 48.77% (285) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_3945 | - | 1e-61 | 45.59% (272) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_4471 | - | 1e-68 | 48.60% (286) | PUTATIVE putative universal stress protein family protein |
| M. ulcerans Agy99 | MUL_2234 | - | 7e-73 | 46.55% (290) | hypothetical protein MUL_2234 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1425|M.vanbaalenii_PYR-1 MAAAAEFGNEIGNVVVGVDDSPSSQPALEWAAAEAKLRNIPLVILYATTL
Mflv_4978|M.gilvum_PYR-GCK MAVTPES----AKVVVGVDDLSSSQPALEWAAAEAGRRGAPLVILYAATL
MSMEG_3945|M.smegmatis_MC2_155 ---------------------------MEWAAKEAVLHKVPLRIVHVMQW
Mb2028c|M.bovis_AF2122/97 MSKPRKQ----HGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVNA
Rv2005c|M.tuberculosis_H37Rv MSKPRKQ----HGVVVGVDGSLESDAAACWGATDAAMRNIPLTVVHVVNA
MUL_2234|M.ulcerans_Agy99 MSTLGKR----LGVVVGVDGSPASNAAVCWAARDAAMRNLPLTVVHVVNT
MMAR_3477|M.marinum_M MSAPMKH----LGIVVGVDGSAASYAAVSWAARDATLRHVPLTLVHMVNQ
MAV_2507|M.avium_104 MAASSKR----CGVLVGVDGSPASNFAVCWAARDAAMRNVPLTLVHMVN-
TH_4471|M.thermoresistible__bu MAIPAIQ----DSIVAGVDGSPSSAAAVEWAARNAALRDRPLVLVHVVPS
MAB_2489|M.abscessus_ATCC_1997 MTTSTPN----SHILVGVDGSTSALHALTWAGAEAQRRNLPLTLVHVIDH
*.. :* : ** :::
Mvan_1425|M.vanbaalenii_PYR-1 -PIG--AWPVVPVPTGFLDWQRQIGQDILKDAGQIAKELTGGAVPVTAEF
Mflv_4978|M.gilvum_PYR-GCK -PIG--AWPVVPVPTGFLDWQRQIGQEILADARQIAEKLTAGAIPVTAEF
MSMEG_3945|M.smegmatis_MC2_155 -PPGSATWSEIPAPTTLADQLKRNAEQLLKEARKVAEDVVGGAVEIHVDD
Mb2028c|M.bovis_AF2122/97 ---DVATWPPMPYPETWGVWQEDEGRQIVANAVKLAKEAVGADRKLSVKS
Rv2005c|M.tuberculosis_H37Rv ---DVATWPPMPYPETWGVWQEDEGRQIVANAVKLAKEAVGADRKLSVKS
MUL_2234|M.ulcerans_Agy99 ---DVATWPPMPYPDTWAVWQEDEGRKVIAGAVKIAEDSVAGDRELTIKS
MMAR_3477|M.marinum_M ---AVPMWPEMPMMTSMSAWQEEDGRQVLEQAGKIAQEVTQQGRDTQIKS
MAV_2507|M.avium_104 ---AATVWPQVPMAAEAVAWQEDDGRRVLQEAVKIAEDATRNGRNLAITT
TH_4471|M.thermoresistible__bu PMVTTAPWPQLPLPDDAFRVMQEEGERLLAQARAAAEQAGAG----EVRT
MAB_2489|M.abscessus_ATCC_1997 --SSLGQGYNLGASASFFQHLETDGAEFLSQAKDHVYALHPN---VEVST
: . . .: * .
Mvan_1425|M.vanbaalenii_PYR-1 AVAT--PTAALVEASHTAGMVVVGSRGQGGLLRKVLGSTSMGVIHRAHCP
Mflv_4978|M.gilvum_PYR-GCK AVAT--PTAALVEESRTAGMVVVGSRGRGGFARKVLGSTSMGLVHRAHCP
MSMEG_3945|M.smegmatis_MC2_155 VVVAGSVVAALTELSESSRLLVVGCRGLGPIGRRLLGSVTAGLIRHARCP
Mb2028c|M.bovis_AF2122/97 ELVFSTPVPTMVEISNEAEMVVLGSSGRGALARGLLGSVSSSLVRRAGCP
Rv2005c|M.tuberculosis_H37Rv ELVFSTPVPTMVEISNEAEMVVLGSSGRGALARGLLGSVSSSLVRRAGCP
MUL_2234|M.ulcerans_Agy99 EIVFSLPVPTMVEMSAEAELMVVGSSGHGALARVLLGSVSSSLVRRASCP
MMAR_3477|M.marinum_M ELRWSAPVPTFVELSQEADLVVVGSHGRGAVARGLLGSVSSGVVHRAHCP
MAV_2507|M.avium_104 ELWHAPPAPTLAQLSEEAELVVVGSTGRGAIGRLLLGSVSSGLVRRARCP
TH_4471|M.thermoresistible__bu AVLQAGIVGTLTELSRDADRIVVGSRGQTALGRMLLGSVSTGLVHQAECP
MAB_2489|M.abscessus_ATCC_1997 VKATGRPVPVLVELSRNALMTVLGSSGLGGFTGMMAGSVSVSLTAKGHSP
. .:.: * : *:*. * . : **.: .: :. .*
Mvan_1425|M.vanbaalenii_PYR-1 VVVVHDE--EPAPPG---GAPVVLGFDGSPGSEAAVEIAFQEASRRGVGL
Mflv_4978|M.gilvum_PYR-GCK VVVVRDD--GSAPAS---DAPVLLGFDGSASAAPAVEIAFQEASQRGVGL
MSMEG_3945|M.smegmatis_MC2_155 VAVIHGESKASAIAT---TAPVVVGVDGSPASEKALEFAFDAASRRGAPL
Mb2028c|M.bovis_AF2122/97 VAVIHSDDAVIPDPQ---HAPVLVGIDGSPVSELATAVAFDEASRRGVEL
Rv2005c|M.tuberculosis_H37Rv VAVIHSDDAVIPDPQ---HAPVLVGIDGSPVSELATAVAFDEASRRGVEL
MUL_2234|M.ulcerans_Agy99 VAVIRDEDPMIPDPL---HAPVLVGIDGSPASELATAVAFDEASRRGVEL
MMAR_3477|M.marinum_M VAVIRDEDPEAPQPEDRDRAPVVVGIDGSSASELATAIAFDEASRRGVEL
MAV_2507|M.avium_104 VAVIHDEDPMMPYPQ---RAPVLVGIDGSPASELATAIAFDEALRRGVDL
TH_4471|M.thermoresistible__bu VVIVRDGDQ--PPGD----APVLVGIDGSPASELATEVAFEEASVRQVEL
MAB_2489|M.abscessus_ATCC_1997 VVVVRES----PVPG---GGPVVVGIDDSESSDGAAAWAFEEAAMRETEL
*.::: . .**::*.*.* : * **: * * . *
Mvan_1425|M.vanbaalenii_PYR-1 VALHSWWSP------GAFEMPGFDWEEIRPEVEQEAARQLAPWQKRYPGV
Mflv_4978|M.gilvum_PYR-GCK VAVHAWWSP------GAFEMPGFDWEEVRPDVEREASRQLSDWQRRYPGV
MSMEG_3945|M.smegmatis_MC2_155 LAVHAWSDA------NVAGYPGVRWDDLRVQAEESLSERLAGWQERYPDV
Mb2028c|M.bovis_AF2122/97 IAVHAWSDV------EVVELPGLDFSAVQQEAELSLAERLAGWQERYPDV
Rv2005c|M.tuberculosis_H37Rv IAVHAWSDV------EVVELPGLDFSAVQQEAELSLAERLAGWQERYPDV
MUL_2234|M.ulcerans_Agy99 IAVHAWSDQ------GVVELPGLNWSTMEAEARLSLAERLAGWEERYPDV
MMAR_3477|M.marinum_M KAVHAWSDL------EVVDLPGLDWSTVKGEAEETLAERLAGWQERYPDV
MAV_2507|M.avium_104 NAVHAWSDT------QVFGLPGMDWPAVRSQAERSLAERLAGWQERYPDV
TH_4471|M.thermoresistible__bu VALHGWRDT------SLFHYPGLDTESLQTQAEAVLAERLAGWQERYPDV
MAB_2489|M.abscessus_ATCC_1997 VAVHVWNNIPPGYVYAYTAWSAMDSAGEQQRQEQLLAERLAGWQEKYPDV
*:* * . ... . . :.:*: *:.:**.*
Mvan_1425|M.vanbaalenii_PYR-1 AVERVVVSDEPARRLVERSESAQLLIVGSHGYGAVTGALLGSVSGAVVQA
Mflv_4978|M.gilvum_PYR-GCK PVELVVVRDQPARRLVERSGAAQLLVVGSHGYGAVTGSLLGSVSGAVVQA
MSMEG_3945|M.smegmatis_MC2_155 HVRREVVLDRPDRRLLKRSEIAQLTVVGSHGRGGFAGLLLGSVSTSVAEA
Mb2028c|M.bovis_AF2122/97 PVSRVVVCDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLGSVSNAVLHA
Rv2005c|M.tuberculosis_H37Rv PVSRVVVCDRPARKLVQKSASAQLVVVGSHGRGGLTGMLLGSVSNAVLHA
MUL_2234|M.ulcerans_Agy99 TVRRVVVCDEPAHQLVEMSQTVQLVVVGSHGRGGITGVLLGSVSNAVVHA
MMAR_3477|M.marinum_M TVDRVVVCDRPARQLIDQAQTAQLVVLGSHGRGGFTSMLVGSTSNAVLHA
MAV_2507|M.avium_104 TVHRMVVCDRPARQLIEQSESAQLTVVGSHGRGGLAGTLLGSVSNAVVHS
TH_4471|M.thermoresistible__bu TVRRVVVAEHPARALVQRAEEAQLVVVGSRGRSGLTGKLLGSVSTGVVHS
MAB_2489|M.abscessus_ATCC_1997 PVRRVVAVGHPADVLLSQAAGAQLIVTGSRGRGDIAGFFLGSTSHALIHK
* *. .* *:. : .** : **:* . .:. ::**.* .: .
Mvan_1425|M.vanbaalenii_PYR-1 ARVPVMVVRPRTP
Mflv_4978|M.gilvum_PYR-GCK ATTPVMVVRPGDS
MSMEG_3945|M.smegmatis_MC2_155 AERPVVVVRG---
Mb2028c|M.bovis_AF2122/97 ARVPVIVARQS--
Rv2005c|M.tuberculosis_H37Rv ARVPVIVARQS--
MUL_2234|M.ulcerans_Agy99 VRMPVIVARSS--
MMAR_3477|M.marinum_M VHTPVIVARSA--
MAV_2507|M.avium_104 VRMPVIVARPS--
TH_4471|M.thermoresistible__bu VRVPVMVARPR--
MAB_2489|M.abscessus_ATCC_1997 ASCPVLVAPRT--
. **:*.