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EWAAKEAVLHKVPLRIVHVMQWPPGSATWSEIPAPTTLADQLKRNAEQLLKEARKVAEDVVGGAVEIHVD DVVVAGSVVAALTELSESSRLLVVGCRGLGPIGRRLLGSVTAGLIRHARCPVAVIHGESKASAIATTAPV VVGVDGSPASEKALEFAFDAASRRGAPLLAVHAWSDANVAGYPGVRWDDLRVQAEESLSERLAGWQERYP DVHVRREVVLDRPDRRLLKRSEIAQLTVVGSHGRGGFAGLLLGSVSTSVAEAAERPVVVVRG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3945 | - | - | 100% (273) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_3940 | - | 2e-65 | 48.53% (272) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_3950 | - | 3e-60 | 45.22% (272) | universal stress protein family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2656 | TB31.7 | 2e-68 | 48.90% (272) | hypothetical protein Mb2656 |
| M. gilvum PYR-GCK | Mflv_4382 | - | 6e-69 | 49.28% (276) | UspA domain-containing protein |
| M. tuberculosis H37Rv | Rv2623 | TB31.7 | 2e-68 | 48.90% (272) | hypothetical protein Rv2623 |
| M. leprae Br4923 | MLBr_01390 | - | 4e-06 | 44.26% (61) | hypothetical protein MLBr_01390 |
| M. abscessus ATCC 19977 | MAB_2489 | - | 3e-35 | 34.67% (274) | hypothetical protein MAB_2489 |
| M. marinum M | MMAR_5410 | - | 1e-68 | 47.48% (278) | hypothetical protein MMAR_5410 |
| M. avium 104 | MAV_2507 | - | 1e-71 | 51.11% (270) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_4471 | - | 7e-62 | 47.25% (273) | PUTATIVE putative universal stress protein family protein |
| M. ulcerans Agy99 | MUL_5033 | - | 1e-67 | 46.76% (278) | hypothetical protein MUL_5033 |
| M. vanbaalenii PYR-1 | Mvan_1963 | - | 9e-71 | 50.00% (276) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4382|M.gilvum_PYR-GCK MSTQPAPLGIVVGVDGSAASRVAVDWAARDAALRQVPLTLAYVLPG--AA
Mvan_1963|M.vanbaalenii_PYR-1 MSTQPAPVGIVVAVDGSDASRVAVDWAARDAAMRRIPLTLAHVLPS--AA
Mb2656|M.bovis_AF2122/97 MSSGNSSLGIIVGIDDSPAAQVAVRWAARDAELRKIPLTLVHAVSP---E
Rv2623|M.tuberculosis_H37Rv MSSGNSSLGIIVGIDDSPAAQVAVRWAARDAELRKIPLTLVHAVSP---E
MAV_2507|M.avium_104 MAASSKRCGVLVGVDGSPASNFAVCWAARDAAMRNVPLTLVHMVN----A
MSMEG_3945|M.smegmatis_MC2_155 -----------------------MEWAAKEAVLHKVPLRIVHVMQWPP-G
MMAR_5410|M.marinum_M MSTESTSPAIVVGVDGSPASTLAVEWAARDAEMRNVPLKVVHVFAPMVTP
MUL_5033|M.ulcerans_Agy99 MSTESTSPAIVVGVDGSPASTLAVDWAARDAEMRNVPLKVVHVFAPMVAP
TH_4471|M.thermoresistible__bu MAIPAIQDSIVAGVDGSPSSAAAVEWAARNAALRDRPLVLVHVVPSPMVT
MAB_2489|M.abscessus_ATCC_1997 MTTSTPNSHILVGVDGSTSALHALTWAGAEAQRRNLPLTLVHVIDHS--S
MLBr_01390|M.leprae_Br4923 ---MGAYQTVVVGTDGSDSSLRAVDRAGKIAGSDAKLIIASAYLPQH--D
: *. * : .
Mflv_4382|M.gilvum_PYR-GCK VQSWIQVPLPASFYEDEKAEATRVLADARAVVDAATQAHPLPAVTEKVLS
Mvan_1963|M.vanbaalenii_PYR-1 TQSWIQVPLPAAFFEDEKLEAERILADARALVTAATEGGEALTVDEVVLS
Mb2656|M.bovis_AF2122/97 VATWLEVPLPPGVLRWQQDHGRHLIDDALKVVEQASLRAGPPTVHSEIVP
Rv2623|M.tuberculosis_H37Rv VATWLEVPLPPGVLRWQQDHGRHLIDDALKVVEQASLRAGPPTVHSEIVP
MAV_2507|M.avium_104 ATVWPQVPMAAEAVAWQEDDGRRVLQEAVKIAEDATRNGRNLAITTELWH
MSMEG_3945|M.smegmatis_MC2_155 SATWSEIPAPTTLADQLKRNAEQLLKEARKVAEDVVGGAVEIHVDDVVVA
MMAR_5410|M.marinum_M ANGWADVAMPADYARWREDQAHQIVQQAHAVAVDAAAPGRAAHVTSEVRY
MUL_5033|M.ulcerans_Agy99 ANGWADVAMPADYARWREDQAHQIVQQAHAVAVDAAAPGRAAHVTSEVRY
TH_4471|M.thermoresistible__bu TAPWPQLPLPDDAFRVMQEEGERLLAQARAAAEQAGAG----EVRTAVLQ
MAB_2489|M.abscessus_ATCC_1997 LGQGYNLGASASFFQHLETDGAEFLSQAKDHVYALHPN---VEVSTVKAT
MLBr_01390|M.leprae_Br4923 NARAFDILKDESYKVTGTAPIYEILHDAKERAHAAGAKN----VEERPVV
:: ..: :* . :
Mflv_4382|M.gilvum_PYR-GCK GQPVPTLADLSR--DADMIVVGSRGMGKWERRVLGSVSSGLVHHARCPVA
Mvan_1963|M.vanbaalenii_PYR-1 GQPVAALVDLAK--DAEMLVMGSRGLGKWERRLLGSVSSGVVHHAHCPVA
Mb2656|M.bovis_AF2122/97 AAAVPTLVDMSK--DAVLMVVGCLGSGRWPGRLLGSVSSGLLRHAHCPVV
Rv2623|M.tuberculosis_H37Rv AAAVPTLVDMSK--DAVLMVVGCLGSGRWPGRLLGSVSSGLLRHAHCPVV
MAV_2507|M.avium_104 APPAPTLAQLSE--EAELVVVGSTGRGAIGRLLLGSVSSGLVRRARCPVA
MSMEG_3945|M.smegmatis_MC2_155 GSVVAALTELSE--SSRLLVVGCRGLGPIGRRLLGSVTAGLIRHARCPVA
MMAR_5410|M.marinum_M AAIVPAMVELSQ--QAEMVVVGCRGQGGVASALLGSVSSGLAHHAHCPVA
MUL_5033|M.ulcerans_Agy99 AAIVPAMVELSL--QAEMVVVGCRGQGGVASALLGSVSSGLAHHAHCPVA
TH_4471|M.thermoresistible__bu AGIVGTLTELSR--DADRIVVGSRGQTALGRMLLGSVSTGLVHQAECPVV
MAB_2489|M.abscessus_ATCC_1997 GRPVPVLVELSR--NALMTVLGSSGLGGFTGMMAGSVSVSLTAKGHSPVV
MLBr_01390|M.leprae_Br4923 GAPVDALVNLAEKTNADLLVVGNVGLSTIAGRLLGSVPANVSRRAKIDVL
. . .:.::: .: *:* * : ***. .: :.. *
Mflv_4382|M.gilvum_PYR-GCK VIYDEDPLIPHPAQAPVVVGIDGSPASERATAIAFDEACRRGVDLVAVHT
Mvan_1963|M.vanbaalenii_PYR-1 VIHDVDPLIPHPAQAPVVVGVDGSPASEHATAIAFDEASFRGVDLVAVHT
Mb2656|M.bovis_AF2122/97 IIHDEDSVMPHPQQAPVLVGVDGSSASELATAIAFDEASRRNVDLVALHA
Rv2623|M.tuberculosis_H37Rv IIHDEDSVMPHPQQAPVLVGVDGSSASELATAIAFDEASRRNVDLVALHA
MAV_2507|M.avium_104 VIHDEDPMMPYPQRAPVLVGIDGSPASELATAIAFDEALRRGVDLNAVHA
MSMEG_3945|M.smegmatis_MC2_155 VIHGESKASAIATTAPVVVGVDGSPASEKALEFAFDAASRRGAPLLAVHA
MMAR_5410|M.marinum_M IIHDDEALPPRSAQAPVLVGVDGSPTSELATEIAFDEASRRGAELVALHA
MUL_5033|M.ulcerans_Agy99 IIHDDEPLPPRSAQAPVLVGVDGSPTSELATEIGFDEASRRGAELVALHA
TH_4471|M.thermoresistible__bu IVRDGDQP---PGDAPVLVGIDGSPASELATEVAFEEASVRQVELVALHG
MAB_2489|M.abscessus_ATCC_1997 VVRE----SPVPGGGPVVVGIDDSESSDGAAAWAFEEAAMRETELVAVHV
MLBr_01390|M.leprae_Br4923 IVHTTH--------------------------------------------
::
Mflv_4382|M.gilvum_PYR-GCK WSDAG--YELPGVEWT-----EVQPEEEMLLSERLAGWHERYPDVTVHRV
Mvan_1963|M.vanbaalenii_PYR-1 WSDAG--YELPGTGWA-----EIQPEEDMLLAERLAGWQERYPDVTVHRV
Mb2656|M.bovis_AF2122/97 WSDVDV-SEWPGIDWP-----ATQSMAEQVLAERLAGWQERYPNVAITRV
Rv2623|M.tuberculosis_H37Rv WSDVDV-SEWPGIDWP-----ATQSMAEQVLAERLAGWQERYPNVAITRV
MAV_2507|M.avium_104 WSDTQV-FGLPGMDWP-----AVRSQAERSLAERLAGWQERYPDVTVHRM
MSMEG_3945|M.smegmatis_MC2_155 WSDANV-AGYPGVRWD-----DLRVQAEESLSERLAGWQERYPDVHVRRE
MMAR_5410|M.marinum_M WTDMGP-LDFPSINWAPIEWSNIKDQEEEVLAERLCGWQERYPDVVTHKV
MUL_5033|M.ulcerans_Agy99 WTDMGP-LDFPSINWAPIEWSNIKDQEEEVLAERLCGWQERYPDVVTHKV
TH_4471|M.thermoresistible__bu WRDTSL-FHYPGLDTE-----SLQTQAEAVLAERLAGWQERYPDVTVRRV
MAB_2489|M.abscessus_ATCC_1997 WNNIPPGYVYAYTAWSAMDSAGEQQRQEQLLAERLAGWQEKYPDVPVRRV
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Mflv_4382|M.gilvum_PYR-GCK VRRDQPARRLLEEAEKAQLLVVGSHGRGGFTGMLLGSVGSQIVQSSRTPV
Mvan_1963|M.vanbaalenii_PYR-1 VCRDQPARRLLEEAAKGQLLVVGSHGRGGFGGMLLGSVGSQVVQSARGPV
Mb2656|M.bovis_AF2122/97 VVRDQPARQLVQRSEEAQLVVVGSRGRGGYAGMLVGSVGETVAQLARTPV
Rv2623|M.tuberculosis_H37Rv VVRDQPARQLVQRSEEAQLVVVGSRGRGGYAGMLVGSVGETVAQLARTPV
MAV_2507|M.avium_104 VVCDRPARQLIEQSESAQLTVVGSHGRGGLAGTLLGSVSNAVVHSVRMPV
MSMEG_3945|M.smegmatis_MC2_155 VVLDRPDRRLLKRSEIAQLTVVGSHGRGGFAGLLLGSVSTSVAEAAERPV
MMAR_5410|M.marinum_M VVSDRPAPRLLEHAHDAQLVVVGSHGRGGFPGMLLGSVSRAVINSARIPV
MUL_5033|M.ulcerans_Agy99 VVSDRPAPRLLEHAHDAQLVVVGSHGRGGFPGMLLGSVSRAVVNSARIPV
TH_4471|M.thermoresistible__bu VVAEHPARALVQRAEEAQLVVVGSRGRSGLTGKLLGSVSTGVVHSVRVPV
MAB_2489|M.abscessus_ATCC_1997 VAVGHPADVLLSQAAGAQLIVTGSRGRGDIAGFFLGSTSHALIHKASCPV
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Mflv_4382|M.gilvum_PYR-GCK IVARTA---
Mvan_1963|M.vanbaalenii_PYR-1 IVARR----
Mb2656|M.bovis_AF2122/97 IVARESLT-
Rv2623|M.tuberculosis_H37Rv IVARESLT-
MAV_2507|M.avium_104 IVARPS---
MSMEG_3945|M.smegmatis_MC2_155 VVVRG----
MMAR_5410|M.marinum_M IIARTPPNS
MUL_5033|M.ulcerans_Agy99 IIARTPANS
TH_4471|M.thermoresistible__bu MVARPR---
MAB_2489|M.abscessus_ATCC_1997 LVAPRT---
MLBr_01390|M.leprae_Br4923 ---------