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LAALDSSVTSRTQARADHFRSGLLFALASAFAFGCSGPFAKALMTAGWSPTAAVTARLAGGALAMAVFAT VVRPGWVREARHHARTVVLYGIVPIAGAQLFYFNAVAHLSVGVALLLEYTAPLLVVGWLWATTRHRPSGM TLAGVVLAVGGITLVLGIIGPGGVAAAHINLAGVGWGLAAAVCAACYFLMSDKAGAMSDKEVADGRPSLH PITLAAAGLAFGAVTVAALGFSGLMPLAFTANDAVIAGFTTPWIVPVIALALIPTAIAYTLGIVGIARLR PRFASMVGLSEVMFAVLAAWMLLGEGMAAAQVIGGAIVLAGLALARQGDRGELVGETNVGETSVTPTALP QTTPVARGGPATIDP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4964 | - | - | 100% (365) | hypothetical protein Mflv_4964 |
| M. gilvum PYR-GCK | Mflv_3133 | - | 5e-10 | 26.16% (279) | hypothetical protein Mflv_3133 |
| M. gilvum PYR-GCK | Mflv_3467 | - | 2e-05 | 28.83% (163) | hypothetical protein Mflv_3467 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3160 | PPE51 | 3e-05 | 23.58% (352) | PPE family protein |
| M. tuberculosis H37Rv | Rv3136 | PPE51 | 3e-05 | 23.58% (352) | PPE family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3762 | - | 1e-90 | 50.75% (335) | hypothetical protein MAB_3762 |
| M. marinum M | MMAR_4118 | - | 8e-12 | 25.76% (264) | membrane permease |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1530 | - | 1e-119 | 67.09% (316) | integral membrane protein |
| M. thermoresistible (build 8) | TH_0035 | - | 1e-114 | 61.42% (337) | integral membrane protein |
| M. ulcerans Agy99 | MUL_3984 | - | 7e-12 | 25.76% (264) | membrane permease |
| M. vanbaalenii PYR-1 | Mvan_1442 | - | 1e-146 | 79.46% (336) | hypothetical protein Mvan_1442 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4964|M.gilvum_PYR-GCK MAALDSSVTSRTQARADHFRSGLLFALASAFAFGCSGPFAKALMTAGWSP
Mvan_1442|M.vanbaalenii_PYR-1 MAALDTSRQAR-ADQTHLFRTGLLFAIGSAFAFGSSGPFAKSLMEAGWTP
MSMEG_1530|M.smegmatis_MC2_155 MATATSPTHVDSTTSGNQFRLGLLFAVGSALAFGSSGPFAKALIEAGWSP
TH_0035|M.thermoresistible__bu --------LARIHSAVNHFRLGLVFAIASASAFGMSGPLAKSLLEAGWSP
MAB_3762|M.abscessus_ATCC_1997 ------------MNDKANFRAGVILALVSAATFGFSGPFAKSLMAAGWSL
MMAR_4118|M.marinum_M --------------MASRTPLPVLMILGSCISLQLGAAIATPLLAH-FGA
MUL_3984|M.ulcerans_Agy99 --------------MASRTPLPVLMILGSCVSLQLGAAIATPLLAH-FGA
Mb3160|M.bovis_AF2122/97 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDS-LAAELATTAEAYGSVL
Rv3136|M.tuberculosis_H37Rv MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDS-LAAELATTAEAYGSVL
:: . .. :*..
Mflv_4964|M.gilvum_PYR-GCK TAAVTARLAGGALAMAVFATVVRPGWVREARHHARTVVLYGIVPIAGAQL
Mvan_1442|M.vanbaalenii_PYR-1 TAAVTARLAGGALAMAVFATITYPGWLREARRHARTVALYGLVPIAGAQL
MSMEG_1530|M.smegmatis_MC2_155 TAAVTARLAGGALLMAIFATFARPGWVKEALQHSRTVIAYGLIPIAGAQF
TH_0035|M.thermoresistible__bu AAAVTARLTGGALVLALFATAIKPGWLREAVRHRHTVVLYGIVPVAGTQL
MAB_3762|M.abscessus_ATCC_1997 TAVVTARLATGAAVMVVAACIAAPGWFSEARRHAKVVVLYGIIPVAGAQF
MMAR_4118|M.marinum_M GLTTGVRLLFAATLLMAIHRPRAFGWDRQQWRSAALFAVA----LAGMNG
MUL_3984|M.ulcerans_Agy99 GLTTGVRLLFAATLLMAIHRPRAFGWDRQQWRSAALFAVA----LAGMNG
Mb3160|M.bovis_AF2122/97 SGLAALHWRGPAAESMAVTAAPYIGWLYTTAEKTQQTAIQ-----ARAAA
Rv3136|M.tuberculosis_H37Rv SGLAALHWRGPAAESMAVTAAPYIGWLYTTAEKTQQTAIQ-----ARAAA
. : * ** . *
Mflv_4964|M.gilvum_PYR-GCK FYFNAVAHLSVGVALLLEYTAPLLVVGWLWATTRHRPSGMTLAGVVLAVG
Mvan_1442|M.vanbaalenii_PYR-1 FYFNAVSHLSVGVALLLEYTAPILVVGWLWATTRRRPTTMTLAGVSLAVA
MSMEG_1530|M.smegmatis_MC2_155 FYYNAVAHLSVGVALLLEYTAPVLVVGWVWAVTKRRPSAGTFGGVALAVI
TH_0035|M.thermoresistible__bu AYYHAVSHLSVGVALLLEYTAPILVVGWLWLVHRRTPARLTLAGTALAVG
MAB_3762|M.abscessus_ATCC_1997 CYFGAVRHMSVGVAMLLEFLSPILVIAWTWMITRHRPHTRVLAGATLALS
MMAR_4118|M.marinum_M FFFAAIARIPLGVAVTIEFAGPLMLAAAFSRRPRDLGCVMAAAAAIVVLS
MUL_3984|M.ulcerans_Agy99 FFFAAIARIPLGVAVTIEFAGPLMLAAAFSRRPRDLGCVMAAAAAIVVLS
Mb3160|M.bovis_AF2122/97 LAFEQAYAMTLPPPVVAANRIQLLALIATNFFGQN-TAAIAATEAQYAEM
Rv3136|M.tuberculosis_H37Rv LAFEQAYAMTLPPPVVAANRIQLLALIATNFFGQN-TAAIAATEAQYAEM
: :.: .: :: : . . .
Mflv_4964|M.gilvum_PYR-GCK GITLVLGIIGPGGVAAAHINLAGVGWGLAAAVCAACYFLMSDKAGAMSDK
Mvan_1442|M.vanbaalenii_PYR-1 GIMLVLGIVGPGGLAGAHINLTGVGWGLAAAVCAACYFLMSDKAGAES--
MSMEG_1530|M.smegmatis_MC2_155 GIMLVLDVFS-----GAHINLVGVGFGLAAAVCAACYFMMSNN-------
TH_0035|M.thermoresistible__bu GMTLVLDVFS-----GAHFDVVGLAWGLTAAVCSASYFLMSDR-------
MAB_3762|M.abscessus_ATCC_1997 GMLLVLNIFS-----GGRVEPVGIAWGLGAAVCAAYYFISSHR-------
MMAR_4118|M.marinum_M WDGSKSAALS--------PDLAGVAFALVAACFWALYILAGKRITG---Q
MUL_3984|M.ulcerans_Agy99 WDGSKSAALS--------PDLAGVAFALVAACFWALYILAGKRITG---Q
Mb3160|M.bovis_AF2122/97 WAQDAAAMYG--------YATASAAAALLTPFSPPRQTTNPAGLTA----
Rv3136|M.tuberculosis_H37Rv WAQDAAAMYG--------YATASAAAALLTPFSPPRQTTNPAGLTA----
. .. . .* :. .
Mflv_4964|M.gilvum_PYR-GCK EVADGRPSLHPITLAAAGLAFGAVTVAALG--------------------
Mvan_1442|M.vanbaalenii_PYR-1 -TGDQGP-LHPITLAAGGLIVGAATVAALG--------------------
MSMEG_1530|M.smegmatis_MC2_155 -VDSDGDGLHPYSLAAGGLVVGAVTVAAIG--------------------
TH_0035|M.thermoresistible__bu -VGTGEDGLHPVTLAAGGLLVGAVTVATAG--------------------
MAB_3762|M.abscessus_ATCC_1997 -AGGKAEELQPITLATSGLLVGAVAVGGFG--------------------
MMAR_4118|M.marinum_M QTGHGALSVSMFIAAIVVLPFGIPAVPTLTGQPEKLIPLLGVAVLSSMLP
MUL_3984|M.ulcerans_Agy99 QTGHGALSVSKFIAAIVVLPFGIPAVPTLTGQPEKLIPLLGVAVLSSMLP
Mb3160|M.bovis_AF2122/97 QAAAVSQATDPLSLLIETVTQALQALT-----------------------
Rv3136|M.tuberculosis_H37Rv QAAAVSQATDPLSLLIETVTQALQALT-----------------------
. : . ::
Mflv_4964|M.gilvum_PYR-GCK ------------------FSGLMPLAFTANDAVIAGFTTP-WIVPVIALA
Mvan_1442|M.vanbaalenii_PYR-1 ------------------ATGVMPLTFTANDTVIAGWTTS-WIVPVVALA
MSMEG_1530|M.smegmatis_MC2_155 ------------------TTGIMPMTFATNPVKLGGFETS-WVVPVIALG
TH_0035|M.thermoresistible__bu ------------------AVGIAPLTFTTGDTVIAGVTMS-WLVPVIGLG
MAB_3762|M.abscessus_ATCC_1997 ------------------LTGIMPLTFSTQDVHVAGWNTP-VYVPILVLG
MMAR_4118|M.marinum_M YSLEFAAMRRFSAHTFGVLLSLEPVVAGLAGWILLGQTLS-WVRGLAMVV
MUL_3984|M.ulcerans_Agy99 YSLEFAAMRRFSAHTFGVLLSLEPVVAGLAGWILLGQTLS-WVRGLAMVV
Mb3160|M.bovis_AF2122/97 ------------------IPSFIPEDFTFLDAIFAGYATVGVTQDVESFV
Rv3136|M.tuberculosis_H37Rv ------------------IPSFIPEDFTFLDAIFAGYATVGVTQDVESFV
.. * . * : .
Mflv_4964|M.gilvum_PYR-GCK LIPTAIAYTLGIVG-----------------------------------I
Mvan_1442|M.vanbaalenii_PYR-1 LIPTAIAYTLGIVG-----------------------------------V
MSMEG_1530|M.smegmatis_MC2_155 LIPTALAYTLGIIG-----------------------------------I
TH_0035|M.thermoresistible__bu VIATAIAYTLGIIG-----------------------------------I
MAB_3762|M.abscessus_ATCC_1997 VVTTAIAYITGIAA-----------------------------------I
MMAR_4118|M.marinum_M VVAASIICTLSQPSPASEPSSAKERTPTRDRAQGSAVGRPLARVRNGLQT
MUL_3984|M.ulcerans_Agy99 VVPASIICTLSQPSPASEPSSAKERTPTRDRAQGSAVGRPLARVRNGLQT
Mb3160|M.bovis_AF2122/97 AGTIGAESNLGLLN---------------------------------VGD
Rv3136|M.tuberculosis_H37Rv AGTIGAESNLGLLN---------------------------------VGD
. . .
Mflv_4964|M.gilvum_PYR-GCK ARLRPRFASMVGLSEVMFAVLAAWMLLGEGMAAAQVIGGAIVLAGLALAR
Mvan_1442|M.vanbaalenii_PYR-1 ARLRPRFASLVGLSEVMFAVLAAWVLLGEAMTVTQAVGGAVVLAGLALAR
MSMEG_1530|M.smegmatis_MC2_155 ARLKPRFASLVGLSEVMFAVIIAWIMVGEAMTPIQAVGGAVVLLGLALAR
TH_0035|M.thermoresistible__bu ALLRPRFASLVGLSEVMFATVAAWLLIGETVTPVQAVGGVIVLTGLALAR
MAB_3762|M.abscessus_ATCC_1997 TRLRPSYASLIALTEVLCAVIAGWVLLGETIAPIQYAGAAVILAGLMLAH
MMAR_4118|M.marinum_M SQRREPVAGRDGLPSPRAEWLDADVSLGDSGRFGDKIARISHRANPVDGG
MUL_3984|M.ulcerans_Agy99 AQRREAVAGREGVPSPAAEWLDADVSLGDSGRFGDKIARISHRANPVDGG
Mb3160|M.bovis_AF2122/97 ENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLASVGRANS
Rv3136|M.tuberculosis_H37Rv ENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLASVGRANS
.. .: . . .. .
Mflv_4964|M.gilvum_PYR-GCK QGD----------RGE------LVGETNVGETSVTPTALPQTTPVARGGP
Mvan_1442|M.vanbaalenii_PYR-1 QGD----------RSE------LDEAG-----TVTWPDAPAP--------
MSMEG_1530|M.smegmatis_MC2_155 QGD----------RSERRAHQITDDVSDDISDEICDACWPETPAHGTAFD
TH_0035|M.thermoresistible__bu QGD----------RPVPG----TGDTPTTPVDDGPDRRVPELH-------
MAB_3762|M.abscessus_ATCC_1997 RGSD------TPGEPESSGAGLTASLPAGLKSHGDDSELSVTSVCDATTE
MMAR_4118|M.marinum_M RGEK------APIRSAAQVGPHFGATGSATNHSATDVPRWADEHHSPATH
MUL_3984|M.ulcerans_Agy99 RGEK------APIRSAAQVGPHFGATGSATNHSATDVPRWADEHHSPATH
Mb3160|M.bovis_AF2122/97 IGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAG
Rv3136|M.tuberculosis_H37Rv IGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAG
*.
Mflv_4964|M.gilvum_PYR-GCK ATIDP------------------------
Mvan_1442|M.vanbaalenii_PYR-1 -----------------------------
MSMEG_1530|M.smegmatis_MC2_155 ETISRG-----------------------
TH_0035|M.thermoresistible__bu -----------------------------
MAB_3762|M.abscessus_ATCC_1997 STPSQ------------------------
MMAR_4118|M.marinum_M VTSQSILRRRVRHRHHPARPGPEGAGIQQ
MUL_3984|M.ulcerans_Agy99 VTSQSILRRRVRHRHHPARPGPEGAGIQQ
Mb3160|M.bovis_AF2122/97 RASGVLPRYGVRLTVMAHPPAAG------
Rv3136|M.tuberculosis_H37Rv RASGVLPRYGVRLTVMAHPPAAG------