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AALDTSRQARADQTHLFRTGLLFAIGSAFAFGSSGPFAKSLMEAGWTPTAAVTARLAGGALAMAVFATIT YPGWLREARRHARTVALYGLVPIAGAQLFYFNAVSHLSVGVALLLEYTAPILVVGWLWATTRRRPTTMTL AGVSLAVAGIMLVLGIVGPGGLAGAHINLTGVGWGLAAAVCAACYFLMSDKAGAESTGDQGPLHPITLAA GGLIVGAATVAALGATGVMPLTFTANDTVIAGWTTSWIVPVVALALIPTAIAYTLGIVGVARLRPRFASL VGLSEVMFAVLAAWVLLGEAMTVTQAVGGAVVLAGLALARQGDRSELDEAGTVTWPDAPAP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1442 | - | - | 100% (342) | hypothetical protein Mvan_1442 |
| M. vanbaalenii PYR-1 | Mvan_3392 | - | 2e-11 | 26.09% (276) | hypothetical protein Mvan_3392 |
| M. vanbaalenii PYR-1 | Mvan_5539 | - | 4e-09 | 26.81% (276) | hypothetical protein Mvan_5539 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4964 | - | 1e-146 | 79.46% (336) | hypothetical protein Mflv_4964 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3762 | - | 2e-92 | 54.90% (306) | hypothetical protein MAB_3762 |
| M. marinum M | MMAR_4118 | - | 2e-14 | 23.62% (309) | membrane permease |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1530 | - | 1e-128 | 67.16% (338) | integral membrane protein |
| M. thermoresistible (build 8) | TH_0035 | - | 1e-118 | 66.46% (325) | integral membrane protein |
| M. ulcerans Agy99 | MUL_3984 | - | 1e-13 | 23.89% (293) | membrane permease |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1442|M.vanbaalenii_PYR-1 MAALDTSRQAR-ADQTHLFRTGLLFAIGSAFAFGSSGPFAKSLMEAGWTP
Mflv_4964|M.gilvum_PYR-GCK MAALDSSVTSRTQARADHFRSGLLFALASAFAFGCSGPFAKALMTAGWSP
MSMEG_1530|M.smegmatis_MC2_155 MATATSPTHVDSTTSGNQFRLGLLFAVGSALAFGSSGPFAKALIEAGWSP
TH_0035|M.thermoresistible__bu --------LARIHSAVNHFRLGLVFAIASASAFGMSGPLAKSLLEAGWSP
MAB_3762|M.abscessus_ATCC_1997 ------------MNDKANFRAGVILALVSAATFGFSGPFAKSLMAAGWSL
MMAR_4118|M.marinum_M --------------MASRTPLPVLMILGSCISLQLGAAIATPLLAH-FGA
MUL_3984|M.ulcerans_Agy99 --------------MASRTPLPVLMILGSCVSLQLGAAIATPLLAH-FGA
::: : *. :: ...:*..*: :
Mvan_1442|M.vanbaalenii_PYR-1 TAAVTARLAGGALAMAVFATITYPGWLREARRHARTVALYGLVPIAGAQL
Mflv_4964|M.gilvum_PYR-GCK TAAVTARLAGGALAMAVFATVVRPGWVREARHHARTVVLYGIVPIAGAQL
MSMEG_1530|M.smegmatis_MC2_155 TAAVTARLAGGALLMAIFATFARPGWVKEALQHSRTVIAYGLIPIAGAQF
TH_0035|M.thermoresistible__bu AAAVTARLTGGALVLALFATAIKPGWLREAVRHRHTVVLYGIVPVAGTQL
MAB_3762|M.abscessus_ATCC_1997 TAVVTARLATGAAVMVVAACIAAPGWFSEARRHAKVVVLYGIIPVAGAQF
MMAR_4118|M.marinum_M GLTTGVRLLFAATLLMAIHRPRAFGWDRQQWRSAALFAVA----LAGMNG
MUL_3984|M.ulcerans_Agy99 GLTTGVRLLFAATLLMAIHRPRAFGWDRQQWRSAALFAVA----LAGMNG
.. .** .* : ** : : . :** :
Mvan_1442|M.vanbaalenii_PYR-1 FYFNAVSHLSVGVALLLEYTAPILVVGWLWATTRRRPTTMTLAGVSLAVA
Mflv_4964|M.gilvum_PYR-GCK FYFNAVAHLSVGVALLLEYTAPLLVVGWLWATTRHRPSGMTLAGVVLAVG
MSMEG_1530|M.smegmatis_MC2_155 FYYNAVAHLSVGVALLLEYTAPVLVVGWVWAVTKRRPSAGTFGGVALAVI
TH_0035|M.thermoresistible__bu AYYHAVSHLSVGVALLLEYTAPILVVGWLWLVHRRTPARLTLAGTALAVG
MAB_3762|M.abscessus_ATCC_1997 CYFGAVRHMSVGVAMLLEFLSPILVIAWTWMITRHRPHTRVLAGATLALS
MMAR_4118|M.marinum_M FFFAAIARIPLGVAVTIEFAGPLMLAAAFSRRPRDLGCVMAAAAAIVVLS
MUL_3984|M.ulcerans_Agy99 FFFAAIARIPLGVAVTIEFAGPLMLAAAFSRRPRDLGCVMAAAAAIVVLS
:: *: ::.:***: :*: .*::: . : . ... :.:
Mvan_1442|M.vanbaalenii_PYR-1 GIMLVLGIVGPGGLAGAHINLTGVGWGLAAAVCAACYFLMSDKAGAES--
Mflv_4964|M.gilvum_PYR-GCK GITLVLGIIGPGGVAAAHINLAGVGWGLAAAVCAACYFLMSDKAGAMSDK
MSMEG_1530|M.smegmatis_MC2_155 GIMLVLDVFS-----GAHINLVGVGFGLAAAVCAACYFMMSNN-------
TH_0035|M.thermoresistible__bu GMTLVLDVFS-----GAHFDVVGLAWGLTAAVCSASYFLMSDR-------
MAB_3762|M.abscessus_ATCC_1997 GMLLVLNIFS-----GGRVEPVGIAWGLGAAVCAAYYFISSHR-------
MMAR_4118|M.marinum_M WDGSKSAALS--------PDLAGVAFALVAACFWALYILAGKRITG---Q
MUL_3984|M.ulcerans_Agy99 WDGSKSAALS--------PDLAGVAFALVAACFWALYILAGKRITG---Q
.. : .*:.:.* ** * *:: ...
Mvan_1442|M.vanbaalenii_PYR-1 -TGDQGP-LHPITLAAGGLIVGAATVAALG--------------------
Mflv_4964|M.gilvum_PYR-GCK EVADGRPSLHPITLAAAGLAFGAVTVAALG--------------------
MSMEG_1530|M.smegmatis_MC2_155 -VDSDGDGLHPYSLAAGGLVVGAVTVAAIG--------------------
TH_0035|M.thermoresistible__bu -VGTGEDGLHPVTLAAGGLLVGAVTVATAG--------------------
MAB_3762|M.abscessus_ATCC_1997 -AGGKAEELQPITLATSGLLVGAVAVGGFG--------------------
MMAR_4118|M.marinum_M QTGHGALSVSMFIAAIVVLPFGIPAVPTLTGQPEKLIPLLGVAVLSSMLP
MUL_3984|M.ulcerans_Agy99 QTGHGALSVSKFIAAIVVLPFGIPAVPTLTGQPEKLIPLLGVAVLSSMLP
. : * * .* :*
Mvan_1442|M.vanbaalenii_PYR-1 ------------------ATGVMPLTFTANDTVIAGWTTSWIVPVVALAL
Mflv_4964|M.gilvum_PYR-GCK ------------------FSGLMPLAFTANDAVIAGFTTPWIVPVIALAL
MSMEG_1530|M.smegmatis_MC2_155 ------------------TTGIMPMTFATNPVKLGGFETSWVVPVIALGL
TH_0035|M.thermoresistible__bu ------------------AVGIAPLTFTTGDTVIAGVTMSWLVPVIGLGV
MAB_3762|M.abscessus_ATCC_1997 ------------------LTGIMPLTFSTQDVHVAGWNTPVYVPILVLGV
MMAR_4118|M.marinum_M YSLEFAAMRRFSAHTFGVLLSLEPVVAGLAGWILLGQTLSWVRGLAMVVV
MUL_3984|M.ulcerans_Agy99 YSLEFAAMRRFSAHTFGVLLSLEPVVAGLAGWILLGQTLSWVRGLAMVVV
.: *:. : * . : : :
Mvan_1442|M.vanbaalenii_PYR-1 IPTAIAYTLGIVG-----------------------------------VA
Mflv_4964|M.gilvum_PYR-GCK IPTAIAYTLGIVG-----------------------------------IA
MSMEG_1530|M.smegmatis_MC2_155 IPTALAYTLGIIG-----------------------------------IA
TH_0035|M.thermoresistible__bu IATAIAYTLGIIG-----------------------------------IA
MAB_3762|M.abscessus_ATCC_1997 VTTAIAYITGIAA-----------------------------------IT
MMAR_4118|M.marinum_M VAASIICTLSQPSPASEPSSAKERTPTRDRAQGSAVGRPLARVRNGLQTS
MUL_3984|M.ulcerans_Agy99 VPASIICTLSQPSPASEPSSAKERTPTRDRAQGSAVGRPLARVRNGLQTA
:.::: . . :
Mvan_1442|M.vanbaalenii_PYR-1 RLRPRFASLVGLSEVMFAVLAAWVLLGEAMTVTQAVGGAVVLAGLALARQ
Mflv_4964|M.gilvum_PYR-GCK RLRPRFASMVGLSEVMFAVLAAWMLLGEGMAAAQVIGGAIVLAGLALARQ
MSMEG_1530|M.smegmatis_MC2_155 RLKPRFASLVGLSEVMFAVIIAWIMVGEAMTPIQAVGGAVVLLGLALARQ
TH_0035|M.thermoresistible__bu LLRPRFASLVGLSEVMFATVAAWLLIGETVTPVQAVGGVIVLTGLALARQ
MAB_3762|M.abscessus_ATCC_1997 RLRPSYASLIALTEVLCAVIAGWVLLGETIAPIQYAGAAVILAGLMLAHR
MMAR_4118|M.marinum_M QRREPVAGRDGLPSPRAEWLDADVSLGDSGRFGDKIARISHRANPVDGGR
MUL_3984|M.ulcerans_Agy99 QRREAVAGREGVPSPAAEWLDADVSLGDSGRFGDKIARISHRANPVDGGR
: *. .:.. : . : :*: : . . . :
Mvan_1442|M.vanbaalenii_PYR-1 GD----RSE------LDEAG-----TVTWPDAPAP---------------
Mflv_4964|M.gilvum_PYR-GCK GD----RGE------LVGETNVGETSVTPTALPQTTPVARGGPATIDP--
MSMEG_1530|M.smegmatis_MC2_155 GD----RSERRAHQITDDVSDDISDEICDACWPETPAHGTAFDETISRG-
TH_0035|M.thermoresistible__bu GD----RPVPG----TGDTPTTPVDDGPDRRVPELH--------------
MAB_3762|M.abscessus_ATCC_1997 GSDTPGEPESSGAGLTASLPAGLKSHGDDSELSVTSVCDATTESTPSQ--
MMAR_4118|M.marinum_M GEKAPIRSAAQVGPHFGATGSATNHSATDVPRWADEHHSPATHVTSQSIL
MUL_3984|M.ulcerans_Agy99 GEKAPIRSAAQVGPHFGATGSATNHSATDVPRWADEHHSPATHVTSQSIL
*. .
Mvan_1442|M.vanbaalenii_PYR-1 ----------------------
Mflv_4964|M.gilvum_PYR-GCK ----------------------
MSMEG_1530|M.smegmatis_MC2_155 ----------------------
TH_0035|M.thermoresistible__bu ----------------------
MAB_3762|M.abscessus_ATCC_1997 ----------------------
MMAR_4118|M.marinum_M RRRVRHRHHPARPGPEGAGIQQ
MUL_3984|M.ulcerans_Agy99 RRRVRHRHHPARPGPEGAGIQQ