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TTHDMLDKPDALQWRDKKRYLWLMGLIAPTALFVVLPLVWALNALGWHAAAQVPLWIGPILLYVLLPTLD RFFGPDGQNPPDEVMERLENDKYYRYCTYLYIPFQYASVIFGAYLFTASDLGWLGFDGALPWPAKIGLAL SVGLLGGVGINTAHEMGHKKESLERWLAKITLAQTLYGHFYIEHNRGHHVRVATPEDPASARFGETFWEF LPRSVFGSLKSAWELEAKRLERAGKPTWHWSNDVLNAWAMSVVFYGALIAVFGWALVPYILISAIFGFTL LETVNYLEHYGLLRQKLPSGRYERCAPVHSWNSDHIVTNLFLYHLQRHSDHHANPTRRYQTLRSMEGAPN LPSGYASMIALTYFPPVWRMVMDHRVVDHYDGDLTRINIHPRVRDKVLARYGVRGGVDA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4721 | - | - | 100% (410) | alkane 1-monooxygenase |
| M. gilvum PYR-GCK | Mflv_3369 | - | e-114 | 49.75% (404) | alkane 1-monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3280c | alkB | 0.0 | 80.15% (398) | transmembrane alkane 1-monooxygenase AlkB |
| M. tuberculosis H37Rv | Rv3252c | alkB | 0.0 | 80.15% (398) | transmembrane alkane 1-monooxygenase AlkB |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3598c | - | 0.0 | 71.72% (396) | putative alkane-1-monooxygenase AlkB (fatty acid |
| M. marinum M | MMAR_1291 | alkB | 0.0 | 79.95% (409) | transmembrane alkane 1-monooxygenase AlkB |
| M. avium 104 | MAV_4215 | - | 0.0 | 78.88% (412) | alkane-1-monooxygenase |
| M. smegmatis MC2 155 | MSMEG_1839 | - | 0.0 | 89.31% (393) | alkane 1-monooxygenase |
| M. thermoresistible (build 8) | TH_0470 | - | 0.0 | 81.11% (397) | PROBABLE TRANSMEMBRANE ALKANE 1-MONOOXYGENASE ALKB (ALKANE |
| M. ulcerans Agy99 | MUL_2749 | alkB_1 | 1e-180 | 72.19% (392) | transmembrane alkane 1-monooxygenase AlkB_1 |
| M. vanbaalenii PYR-1 | Mvan_1742 | - | 0.0 | 90.43% (397) | alkane 1-monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3280c|M.bovis_AF2122/97 -MTTQIGSGGPEAPRPPEVEEWRDKKRYLWLMGLIAPTALVVMLPLIWGM
Rv3252c|M.tuberculosis_H37Rv -MTTQIGSGGPEAPRPPEVEEWRDKKRYLWLMGLIAPTALVVMLPLIWGM
MMAR_1291|M.marinum_M -MTTQFRSDVPDAPET----EWRDKKRYLWLMGLIAPTALFVVLPIVWGL
MAV_4215|M.avium_104 --MTTVDLQQPSEPAA-----WRDKKRRLWLMGLIAPTALFVMLPLVWAL
Mflv_4721|M.gilvum_PYR-GCK -MTTHDMLDKPD------ALQWRDKKRYLWLMGLIAPTALFVVLPLVWAL
Mvan_1742|M.vanbaalenii_PYR-1 -------MSKPD------VEQWRDKKRYLWLMGLIAPTALFVMLPLIWAL
MSMEG_1839|M.smegmatis_MC2_155 MVAEVDPSAVAD------VGEWRDKKRYLWLMGLIAPTALFVMLPVVWAL
TH_0470|M.thermoresistible__bu ---MTTELSNVD------ATVWRDKKRYLWLLGLVAPTALFFMLPVVWAF
MAB_3598c|M.abscessus_ATCC_199 -MTSNLETGPAQP-----AAQWRDRKRYMWLYGMIPPTAIFIATALVYAM
MUL_2749|M.ulcerans_Agy99 -MTSVAQPKSENP-----VQQRRDRKRYLWLVGLVLPTALPASLALAWVF
. **:** :** *:: ***: .: : :
Mb3280c|M.bovis_AF2122/97 NQLGWHAAAQVPLWIGPILLYVLLPLLDLRFGPDGQNPPDEVTDRLENDK
Rv3252c|M.tuberculosis_H37Rv NQLGWHAAAQVPLWIGPILLYVLLPLLDLRFGPDGQNPPDEVTDRLENDK
MMAR_1291|M.marinum_M NHFGWHLAAQVPLWVGPMLVYILLPLLDLGFGPDGQNPPDEVMERLENDK
MAV_4215|M.avium_104 NRLGWHAAAQVPLWIGPILLYILLPILDLRFGPDGQNPPDEVMERLENDK
Mflv_4721|M.gilvum_PYR-GCK NALGWHAAAQVPLWIGPILLYVLLPTLDRFFGPDGQNPPDEVMERLENDK
Mvan_1742|M.vanbaalenii_PYR-1 NQFGWHVAAQVPLWIGPILLYILLPALDLKFGPDGQNPPDEVMERLENDK
MSMEG_1839|M.smegmatis_MC2_155 NNAGWHAAAQVPFWIGPILLYVLLPLLDLKFGPDGQNPPDEVMERLENDR
TH_0470|M.thermoresistible__bu NKLDWHIAAQVPFWIGPILVYVLLPILDLRFGPDGQNPPDEVMERLENDR
MAB_3598c|M.abscessus_ATCC_199 NQLGWQQFSPVLFWIGPLLVYVILPLLDLNFGADGENAPDEVMEALENDK
MUL_2749|M.ulcerans_Agy99 GKLGWTAVTPVLWWIGPFLLYLLLPALDVFFGPDGENPPDEVMERLENDK
. .* : * *:**:*:*::** ** **.**:*.**** : ****:
Mb3280c|M.bovis_AF2122/97 YYRYCTYIYIPFQYLSVVLGAYLFTAANLSWLGFDGALSWAGKLGVALSV
Rv3252c|M.tuberculosis_H37Rv YYRYCTYIYIPFQYLSVVLGAYLFTAANLSWLGFDGALSWAGKLGVALSV
MMAR_1291|M.marinum_M YYRYCTYIYIPFQYLSVVLGAYLFTASDLGWLGFDGGLNWLGKIGVALSV
MAV_4215|M.avium_104 YYRYCTYVYIPFQYLSVILGAYLFTATDLSWLGFHGGLGWAGKLGLALSV
Mflv_4721|M.gilvum_PYR-GCK YYRYCTYLYIPFQYASVIFGAYLFTASDLGWLGFDGALPWPAKIGLALSV
Mvan_1742|M.vanbaalenii_PYR-1 YYRYCTYLYIPFQYASVIMGAYLFTASDLGWLGFEGGLSWPAKIGLALSV
MSMEG_1839|M.smegmatis_MC2_155 YYRYCTYAYIPFQYASVIVGAYLFTASDLGWLGFDGGLGWPAKIGLALSV
TH_0470|M.thermoresistible__bu YYRYCTYLYIPFQYASFIVGAYLFTATDLGWLGFDGGLGWPAKLGLALSV
MAB_3598c|M.abscessus_ATCC_199 YYRYCTYIFIPFQYASFFLGAYYFTATDLSWIGFDHGISWISKLGIAASI
MUL_2749|M.ulcerans_Agy99 YYRYCTYAFIPLQMVSLVLACYLWSADNLSWLGLGAGLGLISKIGLTMTI
******* :**:* *.....* ::* :*.*:*: .: .*:*:: ::
Mb3280c|M.bovis_AF2122/97 GVLGGVGINTAHEMGHKKDSLERWLSKITLAQTCYGHFYIEHNRGHHVRV
Rv3252c|M.tuberculosis_H37Rv GVLGGVGINTAHEMGHKKDSLERWLSKITLAQTCYGHFYIEHNRGHHVRV
MMAR_1291|M.marinum_M GVLGGVGINTAHEMGHKKDSLERWLSKITLAQTGYGHFYIEHNRGHHVRV
MAV_4215|M.avium_104 GVLGGVGINTAHEMGHKKDSLERWLSKITLAQTCYGHFYIEHNRGHHVRV
Mflv_4721|M.gilvum_PYR-GCK GLLGGVGINTAHEMGHKKESLERWLAKITLAQTLYGHFYIEHNRGHHVRV
Mvan_1742|M.vanbaalenii_PYR-1 GLLGGVGINTAHEMGHKKDSLERWLAKITLAQTLYGHFYIEHNRGHHVRV
MSMEG_1839|M.smegmatis_MC2_155 GVLGGVGINTAHELGHKKDSLERWLSKITLAQTWYGHFYIEHNRGHHVRV
TH_0470|M.thermoresistible__bu GVLGGVGINTAHELGHKKDSLERWLSKITLAQTGYGHFYIEHNRGHHVRV
MAB_3598c|M.abscessus_ATCC_199 GVLGGVGINTAHEMGHKKEELERWLSKITLAQTFYGHFYIEHNRGHHVRV
MUL_2749|M.ulcerans_Agy99 GVVGGVGINTAHELGHKRENLEGWLSKITLAQTLYGHFYIEHNRGHHVRV
*::**********:***::.** **:******* ****************
Mb3280c|M.bovis_AF2122/97 STPEDPASARFGETLWEFLPRSVIGGLRSAVHLEAQRLRRLGVSPWNPMT
Rv3252c|M.tuberculosis_H37Rv STPEDPASARFGETLWEFLPRSVIGGLRSAVHLEAQRLRRLGVSPWNPMT
MMAR_1291|M.marinum_M STPEDPASARFGETFWEFLPRTVFGSLRSAIGLEAQRLRRQGRSPWNPKT
MAV_4215|M.avium_104 ATPEDPASARFGETFWEFLPRSVFGSLRSALRLEAQRLRRLGKNPWNPLT
Mflv_4721|M.gilvum_PYR-GCK ATPEDPASARFGETFWEFLPRSVFGSLKSAWELEAKRLERAGKPTWH---
Mvan_1742|M.vanbaalenii_PYR-1 ATPEDPASARFGETFWEFLPRSVFGSLKSAWELEAKRLERAGKSKWH---
MSMEG_1839|M.smegmatis_MC2_155 ATPEDPASARFGETFWEFLPRSVWGSLRSSWELEAKRLERAGKSKWH---
TH_0470|M.thermoresistible__bu ATPEDPASARFGETFWEFLPRSVFGGLKSGWQLEAQRLRRAGKSPWH---
MAB_3598c|M.abscessus_ATCC_199 ATPEDPASSRFGETFWGFWPRSVWGALRSSWNLEATRMKRLNRFVLH---
MUL_2749|M.ulcerans_Agy99 ATPEDPASARFGESFWMFLPRSMFGSLKSAWELEKSRMQRINKPTLS---
:*******:****::* * **:: *.*:*. ** *:.* .
Mb3280c|M.bovis_AF2122/97 YLRNDVLNAWLMSVVLWGGLIAVFGPALIPFVIIQAVFGFSLLEAVNYLE
Rv3252c|M.tuberculosis_H37Rv YLRNDVLNAWLMSVVLWGGLIAVFGPALIPFVIIQAVFGFSLLEAVNYLE
MMAR_1291|M.marinum_M YPSNDVLNAWAMSVLLWGVLIAVFGLGLIPFVIIQAVFGFCLLEAVNYLE
MAV_4215|M.avium_104 YPSNDVLNAWAMSIVLWGVLIAVFGPGLIPFVVIQAVFGFSLLEAVNYLE
Mflv_4721|M.gilvum_PYR-GCK -WSNDVLNAWAMSVVFYGALIAVFGWALVPYILISAIFGFTLLETVNYLE
Mvan_1742|M.vanbaalenii_PYR-1 -WSNDVLNAWAMSVVLYGALIAVFGWALIPYILISAVFGFTLLEAVNYLE
MSMEG_1839|M.smegmatis_MC2_155 -WSNDVLNAWAMSVVFYGVLIAVFGWGLIPYIVISAVFGFTLLETVNYLE
TH_0470|M.thermoresistible__bu -PSNDVLNAWAMTVVLWGVLIAVFGVGVIPYLLIQAVFGFSLLESVNYLE
MAB_3598c|M.abscessus_ATCC_199 -PSNDVVNAWLMSVVLFGVTIAIFGTAVIPYLIIQAIYGFTFLETVNYLE
MUL_2749|M.ulcerans_Agy99 -MRNDVLNAWIMSVVLFGALTAVFGWQVLPFLIIQGLFGASLLESVNYLE
***:*** *:::::* *:** ::*:::*..::* :**:*****
Mb3280c|M.bovis_AF2122/97 HYGLLR----QKSANGRYERCAPVHSWNSDHIVTNLFLYHLQRHSDHHAN
Rv3252c|M.tuberculosis_H37Rv HYGLLR----QKSANGRYERCAPVHSWNSDHIVTNLFLYHLQRHSDHHAN
MMAR_1291|M.marinum_M HYGLLR----QPTSNGRYERCAPVHSWNSDHIVTNLFLYHLQRHSDHHAN
MAV_4215|M.avium_104 HYGLLRRKIDSPSGKARYERCTPEHSWNSDHVVTNLFLYHLQRHSDHHAN
Mflv_4721|M.gilvum_PYR-GCK HYGLLR----QKLPSGRYERCAPVHSWNSDHIVTNLFLYHLQRHSDHHAN
Mvan_1742|M.vanbaalenii_PYR-1 HYGLLR----KKLDNGRYERCAPVHSWNSDHIVTNLFLYHLQRHSDHHAN
MSMEG_1839|M.smegmatis_MC2_155 HYGLLR----QKTPSGRYERCSPQHSWNSDHIVTNLFLYHLQRHSDHHAN
TH_0470|M.thermoresistible__bu HYGLLR----QKTASGRYERCTPEHSWNSDHLVTNLFLYHLQRHSDHHAN
MAB_3598c|M.abscessus_ATCC_199 HYGLLR----QKNGE-RYERCTPKHSWNSDHLVTNIFLYHLQRHSDHHAN
MUL_2749|M.ulcerans_Agy99 HYGLLR----QRTASGRYERCAPVHSWNSDHIVTNIFLYHLQRHSDHHAN
****** . . *****:* *******:***:**************
Mb3280c|M.bovis_AF2122/97 PTRRYQTLRSMAGAPNLPSGYASMISLTYFPPLWRKVMDHRVLEHYGGDI
Rv3252c|M.tuberculosis_H37Rv PTRRYQTLRSMAGAPNLPSGYASMISLTYFPPLWRKVMDHRVLEHYGGDI
MMAR_1291|M.marinum_M PTRRYQTLRSMDGAPNLPSGYASMISLTYFPPLWRKVMDHRVLEHYGGDI
MAV_4215|M.avium_104 PTRRYQTLRSLDGSPNLPSGYASMISLTYFPPLWRKVMDHRVLAHYGGDI
Mflv_4721|M.gilvum_PYR-GCK PTRRYQTLRSMEGAPNLPSGYASMIALTYFPPVWRMVMDHRVVDHYDGDL
Mvan_1742|M.vanbaalenii_PYR-1 PTRRYQTLRSMEGAPNLPSGYASMIGLTYFPPLWRRMMDHRVLAHYGGDI
MSMEG_1839|M.smegmatis_MC2_155 PTRRYQTLRSMDGAPNLPSGYASMIALTYFPPLWRKVMDHRVLDHYDGDI
TH_0470|M.thermoresistible__bu PTRRYQTLRSLDGSPNLPSGYATMIGLTYIPPLWRRVMDHRVLEHYGGDI
MAB_3598c|M.abscessus_ATCC_199 PTRRYQTLRSMDGAPNLPSGYATMLTLAYFPPLWRKVMDHRVLDHYDGDI
MUL_2749|M.ulcerans_Agy99 PLRRYQTLRSMDGAPNLPSGYATLITLTYFPPLWRKLMDHRVIEHYDGDI
* ********: *:********::: *:*:**:** :*****: **.**:
Mb3280c|M.bovis_AF2122/97 TRVNLHPRVREKALARYGASA-----------------------
Rv3252c|M.tuberculosis_H37Rv TRVNLHPRVREKALARYGASA-----------------------
MMAR_1291|M.marinum_M TKVNLHPRVRDKMLARYGASHQGIG-------------------
MAV_4215|M.avium_104 TRVNVSPRRRAKLLARYPVVTA----------------------
Mflv_4721|M.gilvum_PYR-GCK TRINIHPRVRDKVLARYGVRGGVDA-------------------
Mvan_1742|M.vanbaalenii_PYR-1 TQVNIQPRVRDKVLARYGAAADERSREEKKAADERSREEQGGKA
MSMEG_1839|M.smegmatis_MC2_155 TRVNIHPRVRENVLARYGSPE-VRA-------------------
TH_0470|M.thermoresistible__bu TKVNVHPRVREKVVAKYGGAR-----------------------
MAB_3598c|M.abscessus_ATCC_199 TRVNIQPSKRAKILARYGVTEGAA--------------------
MUL_2749|M.ulcerans_Agy99 TKVNIDPRKRDKILATYGVR------------------------
*::*: * * : :* *