For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TSVAQPKSENPVQQRRDRKRYLWLVGLVLPTALPASLALAWVFGKLGWTAVTPVLWWIGPFLLYLLLPAL DVFFGPDGENPPDEVMERLENDKYYRYCTYAFIPLQMVSLVLACYLWSADNLSWLGLGAGLGLISKIGLT MTIGVVGGVGINTAHELGHKRENLEGWLSKITLAQTLYGHFYIEHNRGHHVRVATPEDPASARFGESFWM FLPRSMFGSLKSAWELEKSRMQRINKPTLSMRNDVLNAWIMSVVLFGALTAVFGWQVLPFLIIQGLFGAS LLESVNYLEHYGLLRQRTASGRYERCAPVHSWNSDHIVTNIFLYHLQRHSDHHANPLRRYQTLRSMDGAP NLPSGYATLITLTYFPPLWRKLMDHRVIEHYDGDITKVNIDPRKRDKILATYGVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2749 | alkB_1 | - | 100% (406) | transmembrane alkane 1-monooxygenase AlkB_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3280c | alkB | 1e-172 | 69.06% (404) | transmembrane alkane 1-monooxygenase AlkB |
| M. gilvum PYR-GCK | Mflv_4721 | - | 1e-180 | 72.19% (392) | alkane 1-monooxygenase |
| M. tuberculosis H37Rv | Rv3252c | alkB | 1e-172 | 69.06% (404) | transmembrane alkane 1-monooxygenase AlkB |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3598c | - | 1e-172 | 67.90% (405) | putative alkane-1-monooxygenase AlkB (fatty acid |
| M. marinum M | MMAR_3516 | alkB_1 | 0.0 | 99.01% (406) | transmembrane alkane 1-monooxygenase AlkB_1 |
| M. avium 104 | MAV_4215 | - | 1e-169 | 66.83% (413) | alkane-1-monooxygenase |
| M. smegmatis MC2 155 | MSMEG_1839 | - | 1e-177 | 69.85% (398) | alkane 1-monooxygenase |
| M. thermoresistible (build 8) | TH_0470 | - | 1e-174 | 71.13% (388) | PROBABLE TRANSMEMBRANE ALKANE 1-MONOOXYGENASE ALKB (ALKANE |
| M. vanbaalenii PYR-1 | Mvan_1742 | - | 1e-177 | 70.71% (396) | alkane 1-monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4721|M.gilvum_PYR-GCK ------MTTHDMLDKPDALQWRDKKRYLWLMGLIAPTALFVVLPLVWALN
Mvan_1742|M.vanbaalenii_PYR-1 ------------MSKPDVEQWRDKKRYLWLMGLIAPTALFVMLPLIWALN
MSMEG_1839|M.smegmatis_MC2_155 -----MVAEVDPSAVADVGEWRDKKRYLWLMGLIAPTALFVMLPVVWALN
TH_0470|M.thermoresistible__bu --------MTTELSNVDATVWRDKKRYLWLLGLVAPTALFFMLPVVWAFN
Mb3280c|M.bovis_AF2122/97 MTTQIGSGGPEAPRPPEVEEWRDKKRYLWLMGLIAPTALVVMLPLIWGMN
Rv3252c|M.tuberculosis_H37Rv MTTQIGSGGPEAPRPPEVEEWRDKKRYLWLMGLIAPTALVVMLPLIWGMN
MAV_4215|M.avium_104 MTT------VDLQQPSEPAAWRDKKRRLWLMGLIAPTALFVMLPLVWALN
MAB_3598c|M.abscessus_ATCC_199 -----MTSNLETGPAQPAAQWRDRKRYMWLYGMIPPTAIFIATALVYAMN
MUL_2749|M.ulcerans_Agy99 -----MTSVAQPKSENPVQQRRDRKRYLWLVGLVLPTALPASLALAWVFG
MMAR_3516|M.marinum_M -----MTSVAQPKSENPVQQWRDRKRYLWLVGLVLPTALPASLALAWVFG
**:** :** *:: ***: .: : :.
Mflv_4721|M.gilvum_PYR-GCK ALGWHAAAQVPLWIGPILLYVLLPTLDRFFGPDGQNPPDEVMERLENDKY
Mvan_1742|M.vanbaalenii_PYR-1 QFGWHVAAQVPLWIGPILLYILLPALDLKFGPDGQNPPDEVMERLENDKY
MSMEG_1839|M.smegmatis_MC2_155 NAGWHAAAQVPFWIGPILLYVLLPLLDLKFGPDGQNPPDEVMERLENDRY
TH_0470|M.thermoresistible__bu KLDWHIAAQVPFWIGPILVYVLLPILDLRFGPDGQNPPDEVMERLENDRY
Mb3280c|M.bovis_AF2122/97 QLGWHAAAQVPLWIGPILLYVLLPLLDLRFGPDGQNPPDEVTDRLENDKY
Rv3252c|M.tuberculosis_H37Rv QLGWHAAAQVPLWIGPILLYVLLPLLDLRFGPDGQNPPDEVTDRLENDKY
MAV_4215|M.avium_104 RLGWHAAAQVPLWIGPILLYILLPILDLRFGPDGQNPPDEVMERLENDKY
MAB_3598c|M.abscessus_ATCC_199 QLGWQQFSPVLFWIGPLLVYVILPLLDLNFGADGENAPDEVMEALENDKY
MUL_2749|M.ulcerans_Agy99 KLGWTAVTPVLWWIGPFLLYLLLPALDVFFGPDGENPPDEVMERLENDKY
MMAR_3516|M.marinum_M KLGWTAVTPVLWWIGPFLLYLLLPALDVFFGPDGENPPDEVMERLENDKY
.* : * ****:*:*::** ** **.**:*.**** : ****:*
Mflv_4721|M.gilvum_PYR-GCK YRYCTYLYIPFQYASVIFGAYLFTASDLGWLGFDGALPWPAKIGLALSVG
Mvan_1742|M.vanbaalenii_PYR-1 YRYCTYLYIPFQYASVIMGAYLFTASDLGWLGFEGGLSWPAKIGLALSVG
MSMEG_1839|M.smegmatis_MC2_155 YRYCTYAYIPFQYASVIVGAYLFTASDLGWLGFDGGLGWPAKIGLALSVG
TH_0470|M.thermoresistible__bu YRYCTYLYIPFQYASFIVGAYLFTATDLGWLGFDGGLGWPAKLGLALSVG
Mb3280c|M.bovis_AF2122/97 YRYCTYIYIPFQYLSVVLGAYLFTAANLSWLGFDGALSWAGKLGVALSVG
Rv3252c|M.tuberculosis_H37Rv YRYCTYIYIPFQYLSVVLGAYLFTAANLSWLGFDGALSWAGKLGVALSVG
MAV_4215|M.avium_104 YRYCTYVYIPFQYLSVILGAYLFTATDLSWLGFHGGLGWAGKLGLALSVG
MAB_3598c|M.abscessus_ATCC_199 YRYCTYIFIPFQYASFFLGAYYFTATDLSWIGFDHGISWISKLGIAASIG
MUL_2749|M.ulcerans_Agy99 YRYCTYAFIPLQMVSLVLACYLWSADNLSWLGLGAGLGLISKIGLTMTIG
MMAR_3516|M.marinum_M YRYCTYAFIPLQMVSLVLACYLWSADNLSWLGLGAGLGLISKIGLTMTIG
****** :**:* *.....* ::* :*.*:*: .: .*:*:: ::*
Mflv_4721|M.gilvum_PYR-GCK LLGGVGINTAHEMGHKKESLERWLAKITLAQTLYGHFYIEHNRGHHVRVA
Mvan_1742|M.vanbaalenii_PYR-1 LLGGVGINTAHEMGHKKDSLERWLAKITLAQTLYGHFYIEHNRGHHVRVA
MSMEG_1839|M.smegmatis_MC2_155 VLGGVGINTAHELGHKKDSLERWLSKITLAQTWYGHFYIEHNRGHHVRVA
TH_0470|M.thermoresistible__bu VLGGVGINTAHELGHKKDSLERWLSKITLAQTGYGHFYIEHNRGHHVRVA
Mb3280c|M.bovis_AF2122/97 VLGGVGINTAHEMGHKKDSLERWLSKITLAQTCYGHFYIEHNRGHHVRVS
Rv3252c|M.tuberculosis_H37Rv VLGGVGINTAHEMGHKKDSLERWLSKITLAQTCYGHFYIEHNRGHHVRVS
MAV_4215|M.avium_104 VLGGVGINTAHEMGHKKDSLERWLSKITLAQTCYGHFYIEHNRGHHVRVA
MAB_3598c|M.abscessus_ATCC_199 VLGGVGINTAHEMGHKKEELERWLSKITLAQTFYGHFYIEHNRGHHVRVA
MUL_2749|M.ulcerans_Agy99 VVGGVGINTAHELGHKRENLEGWLSKITLAQTLYGHFYIEHNRGHHVRVA
MMAR_3516|M.marinum_M VVGGVGINTAHELGHKRENLERWLSKITLAQTLYGHFYIEHNRGHHVRVS
::**********:***::.** **:******* ****************:
Mflv_4721|M.gilvum_PYR-GCK TPEDPASARFGETFWEFLPRSVFGSLKSAWELEAKRLERAGKPTWH----
Mvan_1742|M.vanbaalenii_PYR-1 TPEDPASARFGETFWEFLPRSVFGSLKSAWELEAKRLERAGKSKWH----
MSMEG_1839|M.smegmatis_MC2_155 TPEDPASARFGETFWEFLPRSVWGSLRSSWELEAKRLERAGKSKWH----
TH_0470|M.thermoresistible__bu TPEDPASARFGETFWEFLPRSVFGGLKSGWQLEAQRLRRAGKSPWH----
Mb3280c|M.bovis_AF2122/97 TPEDPASARFGETLWEFLPRSVIGGLRSAVHLEAQRLRRLGVSPWNPMTY
Rv3252c|M.tuberculosis_H37Rv TPEDPASARFGETLWEFLPRSVIGGLRSAVHLEAQRLRRLGVSPWNPMTY
MAV_4215|M.avium_104 TPEDPASARFGETFWEFLPRSVFGSLRSALRLEAQRLRRLGKNPWNPLTY
MAB_3598c|M.abscessus_ATCC_199 TPEDPASSRFGETFWGFWPRSVWGALRSSWNLEATRMKRLNRFVLH----
MUL_2749|M.ulcerans_Agy99 TPEDPASARFGESFWMFLPRSMFGSLKSAWELEKSRMQRINKPTLS----
MMAR_3516|M.marinum_M TPEDPASARFGESFWMFLPRSMFGSLKSAWELEKSRMQRINKPTLS----
*******:****::* * ***: *.*:*. .** *:.* .
Mflv_4721|M.gilvum_PYR-GCK WSNDVLNAWAMSVVFYGALIAVFGWALVPYILISAIFGFTLLETVNYLEH
Mvan_1742|M.vanbaalenii_PYR-1 WSNDVLNAWAMSVVLYGALIAVFGWALIPYILISAVFGFTLLEAVNYLEH
MSMEG_1839|M.smegmatis_MC2_155 WSNDVLNAWAMSVVFYGVLIAVFGWGLIPYIVISAVFGFTLLETVNYLEH
TH_0470|M.thermoresistible__bu PSNDVLNAWAMTVVLWGVLIAVFGVGVIPYLLIQAVFGFSLLESVNYLEH
Mb3280c|M.bovis_AF2122/97 LRNDVLNAWLMSVVLWGGLIAVFGPALIPFVIIQAVFGFSLLEAVNYLEH
Rv3252c|M.tuberculosis_H37Rv LRNDVLNAWLMSVVLWGGLIAVFGPALIPFVIIQAVFGFSLLEAVNYLEH
MAV_4215|M.avium_104 PSNDVLNAWAMSIVLWGVLIAVFGPGLIPFVVIQAVFGFSLLEAVNYLEH
MAB_3598c|M.abscessus_ATCC_199 PSNDVVNAWLMSVVLFGVTIAIFGTAVIPYLIIQAIYGFTFLETVNYLEH
MUL_2749|M.ulcerans_Agy99 MRNDVLNAWIMSVVLFGALTAVFGWQVLPFLIIQGLFGASLLESVNYLEH
MMAR_3516|M.marinum_M MRNDVLNAWIMSVVLFGALTAVFGWQVLPFLIIQGLFGASLLESVNYLEH
***:*** *::*::* *:** ::*:::*..::* ::**:******
Mflv_4721|M.gilvum_PYR-GCK YGLLRQK----LPSGRYERCAPVHSWNSDHIVTNLFLYHLQRHSDHHANP
Mvan_1742|M.vanbaalenii_PYR-1 YGLLRKK----LDNGRYERCAPVHSWNSDHIVTNLFLYHLQRHSDHHANP
MSMEG_1839|M.smegmatis_MC2_155 YGLLRQK----TPSGRYERCSPQHSWNSDHIVTNLFLYHLQRHSDHHANP
TH_0470|M.thermoresistible__bu YGLLRQK----TASGRYERCTPEHSWNSDHLVTNLFLYHLQRHSDHHANP
Mb3280c|M.bovis_AF2122/97 YGLLRQK----SANGRYERCAPVHSWNSDHIVTNLFLYHLQRHSDHHANP
Rv3252c|M.tuberculosis_H37Rv YGLLRQK----SANGRYERCAPVHSWNSDHIVTNLFLYHLQRHSDHHANP
MAV_4215|M.avium_104 YGLLRRKIDSPSGKARYERCTPEHSWNSDHVVTNLFLYHLQRHSDHHANP
MAB_3598c|M.abscessus_ATCC_199 YGLLRQK-----NGERYERCTPKHSWNSDHLVTNIFLYHLQRHSDHHANP
MUL_2749|M.ulcerans_Agy99 YGLLRQR----TASGRYERCAPVHSWNSDHIVTNIFLYHLQRHSDHHANP
MMAR_3516|M.marinum_M YGLLRQR----TASGRYERCAPVHSWNSDHIVTNIFLYHLQRHSDHHANP
*****:: *****:* *******:***:***************
Mflv_4721|M.gilvum_PYR-GCK TRRYQTLRSMEGAPNLPSGYASMIALTYFPPVWRMVMDHRVVDHYDGDLT
Mvan_1742|M.vanbaalenii_PYR-1 TRRYQTLRSMEGAPNLPSGYASMIGLTYFPPLWRRMMDHRVLAHYGGDIT
MSMEG_1839|M.smegmatis_MC2_155 TRRYQTLRSMDGAPNLPSGYASMIALTYFPPLWRKVMDHRVLDHYDGDIT
TH_0470|M.thermoresistible__bu TRRYQTLRSLDGSPNLPSGYATMIGLTYIPPLWRRVMDHRVLEHYGGDIT
Mb3280c|M.bovis_AF2122/97 TRRYQTLRSMAGAPNLPSGYASMISLTYFPPLWRKVMDHRVLEHYGGDIT
Rv3252c|M.tuberculosis_H37Rv TRRYQTLRSMAGAPNLPSGYASMISLTYFPPLWRKVMDHRVLEHYGGDIT
MAV_4215|M.avium_104 TRRYQTLRSLDGSPNLPSGYASMISLTYFPPLWRKVMDHRVLAHYGGDIT
MAB_3598c|M.abscessus_ATCC_199 TRRYQTLRSMDGAPNLPSGYATMLTLAYFPPLWRKVMDHRVLDHYDGDIT
MUL_2749|M.ulcerans_Agy99 LRRYQTLRSMDGAPNLPSGYATLITLTYFPPLWRKLMDHRVIEHYDGDIT
MMAR_3516|M.marinum_M LRRYQTLRSMDGAPNLPSGYATLITLTYFPPLWRKVMDHRVIEHYDGDIT
********: *:********::: *:*:**:** :*****: **.**:*
Mflv_4721|M.gilvum_PYR-GCK RINIHPRVRDKVLARYGVRGGVDA-------------------
Mvan_1742|M.vanbaalenii_PYR-1 QVNIQPRVRDKVLARYGAAADERSREEKKAADERSREEQGGKA
MSMEG_1839|M.smegmatis_MC2_155 RVNIHPRVRENVLARYGSPE-VRA-------------------
TH_0470|M.thermoresistible__bu KVNVHPRVREKVVAKYGGAR-----------------------
Mb3280c|M.bovis_AF2122/97 RVNLHPRVREKALARYGASA-----------------------
Rv3252c|M.tuberculosis_H37Rv RVNLHPRVREKALARYGASA-----------------------
MAV_4215|M.avium_104 RVNVSPRRRAKLLARYPVVTA----------------------
MAB_3598c|M.abscessus_ATCC_199 RVNIQPSKRAKILARYGVTEGAA--------------------
MUL_2749|M.ulcerans_Agy99 KVNIDPRKRDKILATYGVR------------------------
MMAR_3516|M.marinum_M KVNIDPRKRDKILATYGVR------------------------
::*: * * : :* *