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MPTLQRATRGITQRPETALAWHDRKRYVWLLALVIPTLVPMSALAAGLTGSGVFWWSGPFLMFVVIPLAD YLVGADSENPPDSALAMLENDRFYRWGTYAYLPAQYISLVLACWLWSGGAHIPMSDVDKVGLMLTVGGIA GVAINTAHELGHQRARSERWLSKIALAQTGYGHFYVEHNRGHHSRVATPDDPASSRLGESLYAFQFRSIL GSLRSAWRLERRRLNRRGKSVWTLHNDVLNSWLMTAALFSALIAGFGVEVLIWLIGQAIVGICLLESINY LEHYGLRRQRRRDGAYEQVRASHSWNSNSVISNVLLFHLQRHSDHHANPHRRYQALCHADEAPQLPSGYA TMVLLALFPPLWRRVMDPRVLAHYGGDVRRAALPRRARAQRRLLKRYG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3369 | - | - | 100% (398) | alkane 1-monooxygenase |
| M. gilvum PYR-GCK | Mflv_4721 | - | e-114 | 49.75% (404) | alkane 1-monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3280c | alkB | 1e-117 | 52.49% (402) | transmembrane alkane 1-monooxygenase AlkB |
| M. tuberculosis H37Rv | Rv3252c | alkB | 1e-117 | 52.49% (402) | transmembrane alkane 1-monooxygenase AlkB |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3598c | - | 1e-114 | 51.13% (397) | putative alkane-1-monooxygenase AlkB (fatty acid |
| M. marinum M | MMAR_3516 | alkB_1 | 1e-126 | 54.22% (391) | transmembrane alkane 1-monooxygenase AlkB_1 |
| M. avium 104 | MAV_4215 | - | 1e-115 | 50.99% (406) | alkane-1-monooxygenase |
| M. smegmatis MC2 155 | MSMEG_1839 | - | 1e-118 | 52.15% (395) | alkane 1-monooxygenase |
| M. thermoresistible (build 8) | TH_4585 | - | 1e-132 | 60.38% (366) | PUTATIVE alkane 1-monooxygenase |
| M. ulcerans Agy99 | MUL_2749 | alkB_1 | 1e-124 | 53.98% (389) | transmembrane alkane 1-monooxygenase AlkB_1 |
| M. vanbaalenii PYR-1 | Mvan_3100 | - | 0.0 | 81.91% (398) | alkane 1-monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3280c|M.bovis_AF2122/97 MTTQIGSGGPEAPRPPEVEEWRDKKRYLWLMGLIAPTALVVMLPLIWGMN
Rv3252c|M.tuberculosis_H37Rv MTTQIGSGGPEAPRPPEVEEWRDKKRYLWLMGLIAPTALVVMLPLIWGMN
MAV_4215|M.avium_104 MTT------VDLQQPSEPAAWRDKKRRLWLMGLIAPTALFVMLPLVWALN
MSMEG_1839|M.smegmatis_MC2_155 MVA-----EVDPSAVADVGEWRDKKRYLWLMGLIAPTALFVMLPVVWALN
MAB_3598c|M.abscessus_ATCC_199 MTS-----NLETGPAQPAAQWRDRKRYMWLYGMIPPTAIFIATALVYAMN
MMAR_3516|M.marinum_M MTS-----VAQPKSENPVQQWRDRKRYLWLVGLVLPTALPASLALAWVFG
MUL_2749|M.ulcerans_Agy99 MTS-----VAQPKSENPVQQRRDRKRYLWLVGLVLPTALPASLALAWVFG
Mflv_3369|M.gilvum_PYR-GCK MPTLQRATRGITQRPETALAWHDRKRYVWLLALVIPTLVPMSALAAGLTG
Mvan_3100|M.vanbaalenii_PYR-1 MPIQQRSPQRHSRAPVVAQAWRDQKRYGWLLGLVIPTLVPMSWAAAALTG
TH_4585|M.thermoresistible__bu ----VKSDWTAVRVP---RRWADG-RYVWFLGALPPALVYGSWHGVEQTG
* * *: . : *: : .
Mb3280c|M.bovis_AF2122/97 QLGWHAAAQVPLWIGPILLYVLLPLLDLRFGPDGQNPPDEVTDRLENDKY
Rv3252c|M.tuberculosis_H37Rv QLGWHAAAQVPLWIGPILLYVLLPLLDLRFGPDGQNPPDEVTDRLENDKY
MAV_4215|M.avium_104 RLGWHAAAQVPLWIGPILLYILLPILDLRFGPDGQNPPDEVMERLENDKY
MSMEG_1839|M.smegmatis_MC2_155 NAGWHAAAQVPFWIGPILLYVLLPLLDLKFGPDGQNPPDEVMERLENDRY
MAB_3598c|M.abscessus_ATCC_199 QLGWQQFSPVLFWIGPLLVYVILPLLDLNFGADGENAPDEVMEALENDKY
MMAR_3516|M.marinum_M KLGWTAVTPVLWWIGPFLLYLLLPALDVFFGPDGENPPDEVMERLENDKY
MUL_2749|M.ulcerans_Agy99 KLGWTAVTPVLWWIGPFLLYLLLPALDVFFGPDGENPPDEVMERLENDKY
Mflv_3369|M.gilvum_PYR-GCK -------SGVFWWSGPFLMFVVIPLADYLVGADSENPPDSALAMLENDRF
Mvan_3100|M.vanbaalenii_PYR-1 -------AGVFWWSGPALMFLVIPTLDYLVGPDADNPPDSALTWLENDRF
TH_4585|M.thermoresistible__bu -------WPAFWWSGVVVTFMVIPLIDRLVGTSTTNPPENLVPPLEAQRI
. * * : ::::* * .*.. *.*:. ** ::
Mb3280c|M.bovis_AF2122/97 YRYCTYIYIPFQYLSVVLGAYLFTAANLSWLGFDGALSWAGKLGVALSVG
Rv3252c|M.tuberculosis_H37Rv YRYCTYIYIPFQYLSVVLGAYLFTAANLSWLGFDGALSWAGKLGVALSVG
MAV_4215|M.avium_104 YRYCTYVYIPFQYLSVILGAYLFTATDLSWLGFHGGLGWAGKLGLALSVG
MSMEG_1839|M.smegmatis_MC2_155 YRYCTYAYIPFQYASVIVGAYLFTASDLGWLGFDGGLGWPAKIGLALSVG
MAB_3598c|M.abscessus_ATCC_199 YRYCTYIFIPFQYASFFLGAYYFTATDLSWIGFDHGISWISKLGIAASIG
MMAR_3516|M.marinum_M YRYCTYAFIPLQMVSLVLACYLWSADNLSWLGLGAGLGLISKIGLTMTIG
MUL_2749|M.ulcerans_Agy99 YRYCTYAFIPLQMVSLVLACYLWSADNLSWLGLGAGLGLISKIGLTMTIG
Mflv_3369|M.gilvum_PYR-GCK YRWGTYAYLPAQYISLVLACWLWSG------GAHIPMSDVDKVGLMLTVG
Mvan_3100|M.vanbaalenii_PYR-1 YRWATYLYLPAQYVSLMLACWLWSG------GGGVAMSDVDKVGLMLTIG
TH_4585|M.thermoresistible__bu FRWATYLFVVNQYLALIVACWLWSG------GGAAPMTFVDKLGLALTVG
:*: ** :: * :..:..: ::. * : *:*: ::*
Mb3280c|M.bovis_AF2122/97 VLGGVGINTAHEMGHKKDSLERWLSKITLAQTCYGHFYIEHNRGHHVRVS
Rv3252c|M.tuberculosis_H37Rv VLGGVGINTAHEMGHKKDSLERWLSKITLAQTCYGHFYIEHNRGHHVRVS
MAV_4215|M.avium_104 VLGGVGINTAHEMGHKKDSLERWLSKITLAQTCYGHFYIEHNRGHHVRVA
MSMEG_1839|M.smegmatis_MC2_155 VLGGVGINTAHELGHKKDSLERWLSKITLAQTWYGHFYIEHNRGHHVRVA
MAB_3598c|M.abscessus_ATCC_199 VLGGVGINTAHEMGHKKEELERWLSKITLAQTFYGHFYIEHNRGHHVRVA
MMAR_3516|M.marinum_M VVGGVGINTAHELGHKRENLERWLSKITLAQTLYGHFYIEHNRGHHVRVS
MUL_2749|M.ulcerans_Agy99 VVGGVGINTAHELGHKRENLEGWLSKITLAQTLYGHFYIEHNRGHHVRVA
Mflv_3369|M.gilvum_PYR-GCK GIAGVAINTAHELGHQRARSERWLSKIALAQTGYGHFYVEHNRGHHSRVA
Mvan_3100|M.vanbaalenii_PYR-1 GIGGVAINIAHELGHQRARSERRLSKIALAQTGYGHFFVEHNRGHHARVA
TH_4585|M.thermoresistible__bu LSGGLGINAAHELGHKRPAVERRLSKVALAQTCYGHFFVEHNRGHHARVA
.*:.** ***:**:: * ***::**** ****::******* **:
Mb3280c|M.bovis_AF2122/97 TPEDPASARFGETLWEFLPRSVIGGLRSAVHLEAQRLRRLGVSPWNPMTY
Rv3252c|M.tuberculosis_H37Rv TPEDPASARFGETLWEFLPRSVIGGLRSAVHLEAQRLRRLGVSPWNPMTY
MAV_4215|M.avium_104 TPEDPASARFGETFWEFLPRSVFGSLRSALRLEAQRLRRLGKNPWNPLTY
MSMEG_1839|M.smegmatis_MC2_155 TPEDPASARFGETFWEFLPRSVWGSLRSSWELEAKRLERAGKSKWH----
MAB_3598c|M.abscessus_ATCC_199 TPEDPASSRFGETFWGFWPRSVWGALRSSWNLEATRMKRLNRFVLHP---
MMAR_3516|M.marinum_M TPEDPASARFGESFWMFLPRSMFGSLKSAWELEKSRMQRINKPTLS----
MUL_2749|M.ulcerans_Agy99 TPEDPASARFGESFWMFLPRSMFGSLKSAWELEKSRMQRINKPTLS----
Mflv_3369|M.gilvum_PYR-GCK TPDDPASSRLGESLYAFQFRSILGSLRSAWRLERRRLNRRGKSVWT----
Mvan_3100|M.vanbaalenii_PYR-1 TPEDPASSRLGESIYTFQFRSVLGSLRSAWRLERRRLSRHGKSPWT----
TH_4585|M.thermoresistible__bu TPEDPASARFGESLYRFIPRSVVGGFRSAWRLECDRFERRERSPWT----
**:****:*:**::: * **: *.::*: .** *: *
Mb3280c|M.bovis_AF2122/97 LRNDVLNAWLMSVVLWGGLIAVFGPALIPFVIIQAVFGFSLLEAVNYLEH
Rv3252c|M.tuberculosis_H37Rv LRNDVLNAWLMSVVLWGGLIAVFGPALIPFVIIQAVFGFSLLEAVNYLEH
MAV_4215|M.avium_104 PSNDVLNAWAMSIVLWGVLIAVFGPGLIPFVVIQAVFGFSLLEAVNYLEH
MSMEG_1839|M.smegmatis_MC2_155 WSNDVLNAWAMSVVFYGVLIAVFGWGLIPYIVISAVFGFTLLETVNYLEH
MAB_3598c|M.abscessus_ATCC_199 -SNDVVNAWLMSVVLFGVTIAIFGTAVIPYLIIQAIYGFTFLETVNYLEH
MMAR_3516|M.marinum_M MRNDVLNAWIMSVVLFGALTAVFGWQVLPFLIIQGLFGASLLESVNYLEH
MUL_2749|M.ulcerans_Agy99 MRNDVLNAWIMSVVLFGALTAVFGWQVLPFLIIQGLFGASLLESVNYLEH
Mflv_3369|M.gilvum_PYR-GCK LHNDVLNSWLMTAALFSALIAGFGVEVLIWLIGQAIVGICLLESINYLEH
Mvan_3100|M.vanbaalenii_PYR-1 LRNDVLNSWLMTAALFAVLVAGFGVEVLPWLLGQAVVGICLLESINYLEH
TH_4585|M.thermoresistible__bu LRNDILNAWLLSVALFGGLCLWFGIGVLGWLVVQAVLGCCLLEAVNYIEH
**::*:* :: .::. ** :: ::: ..: * :**::**:**
Mb3280c|M.bovis_AF2122/97 YGLLRQK----SANGRYERCAPVHSWNSDHIVTNLFLYHLQRHSDHHANP
Rv3252c|M.tuberculosis_H37Rv YGLLRQK----SANGRYERCAPVHSWNSDHIVTNLFLYHLQRHSDHHANP
MAV_4215|M.avium_104 YGLLRRKIDSPSGKARYERCTPEHSWNSDHVVTNLFLYHLQRHSDHHANP
MSMEG_1839|M.smegmatis_MC2_155 YGLLRQK----TPSGRYERCSPQHSWNSDHIVTNLFLYHLQRHSDHHANP
MAB_3598c|M.abscessus_ATCC_199 YGLLRQK-----NGERYERCTPKHSWNSDHLVTNIFLYHLQRHSDHHANP
MMAR_3516|M.marinum_M YGLLRQR----TASGRYERCAPVHSWNSDHIVTNIFLYHLQRHSDHHANP
MUL_2749|M.ulcerans_Agy99 YGLLRQR----TASGRYERCAPVHSWNSDHIVTNIFLYHLQRHSDHHANP
Mflv_3369|M.gilvum_PYR-GCK YGLRRQR----RRDGAYEQVRASHSWNSNSVISNVLLFHLQRHSDHHANP
Mvan_3100|M.vanbaalenii_PYR-1 YGLRRQR----RADGTYEQVRPSHSWNSNSVISNVFLFHLQRHSDHHANP
TH_4585|M.thermoresistible__bu YGLRRQR----LPGGRYEPVRPEHSWNSDAMVTNVFLFQLQRHSDHHANP
*** *:: ** . *****: :::*::*::***********
Mb3280c|M.bovis_AF2122/97 TRRYQTLRSMAGAPNLPSGYASMISLTYFPPLWRKVMDHRVLEHYGGDIT
Rv3252c|M.tuberculosis_H37Rv TRRYQTLRSMAGAPNLPSGYASMISLTYFPPLWRKVMDHRVLEHYGGDIT
MAV_4215|M.avium_104 TRRYQTLRSLDGSPNLPSGYASMISLTYFPPLWRKVMDHRVLAHYGGDIT
MSMEG_1839|M.smegmatis_MC2_155 TRRYQTLRSMDGAPNLPSGYASMIALTYFPPLWRKVMDHRVLDHYDGDIT
MAB_3598c|M.abscessus_ATCC_199 TRRYQTLRSMDGAPNLPSGYATMLTLAYFPPLWRKVMDHRVLDHYDGDIT
MMAR_3516|M.marinum_M LRRYQTLRSMDGAPNLPSGYATLITLTYFPPLWRKVMDHRVIEHYDGDIT
MUL_2749|M.ulcerans_Agy99 LRRYQTLRSMDGAPNLPSGYATLITLTYFPPLWRKLMDHRVIEHYDGDIT
Mflv_3369|M.gilvum_PYR-GCK HRRYQALCHADEAPQLPSGYATMVLLALFPPLWRRVMDPRVLAHYGGDVR
Mvan_3100|M.vanbaalenii_PYR-1 HRRYQALCHADEAPQLPSGYATMVLLALFPPLWRRVMDGRVLAHYGGDIR
TH_4585|M.thermoresistible__bu MRRYQTLRHAEDAPQLPAGYAEMLLYALIPPLWRKIMDPRVVAHYGGDLS
****:* :*:**:*** :: : :*****::** **: **.**:
Mb3280c|M.bovis_AF2122/97 RVNLH--PRVREKALARYGASA------------
Rv3252c|M.tuberculosis_H37Rv RVNLH--PRVREKALARYGASA------------
MAV_4215|M.avium_104 RVNVS--PRRRAKLLARYPVVTA-----------
MSMEG_1839|M.smegmatis_MC2_155 RVNIH--PRVRENVLARYGSPEVRA---------
MAB_3598c|M.abscessus_ATCC_199 RVNIQ--PSKRAKILARYGVTEGAA---------
MMAR_3516|M.marinum_M KVNID--PRKRDKILATYGVR-------------
MUL_2749|M.ulcerans_Agy99 KVNID--PRKRDKILATYGVR-------------
Mflv_3369|M.gilvum_PYR-GCK RAALPRRARAQRRLLKRYG---------------
Mvan_3100|M.vanbaalenii_PYR-1 LAALS--PRKERRLLRRYG---------------
TH_4585|M.thermoresistible__bu LVALD--PRTHRRPGSVHAEQNPGVAGTHPIACG
. : . . . :