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MKYLDEFRDPVAARTLVDRINRAATRTWTMMEVCGGQTHSIIRNGIDQLLEGSVEFVHGPGCPVCVTPLE VIDRALEIAARDDVIFCSFGDMLRVPGSHQDLFSVKARGGDVRIVYSPLDATRVAADNPDKQVVFFGVGF ETTAPANAMAVVHAKRLGLKNFSMLVSHVLVPPAMTAILSSPSNRVQGFLAAGHVCSVMGTSEYGPLVEK FDVPIVVTGFEPLDLLEGVRQLVDLLEAGTPELRNAYSRAVTAEGNVFAQQTLSEVFTVTDRQWRGIGMI PRSGWTLSPQYAEFDAELRFGVGHLQVAESAECRSGEVLQGLLKPNECPAFGKTCTPRNPLGATMVSSEG ACAAYYQFRRLEAAAHV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2275 | hypD | - | 100% (367) | hydrogenase expression/formation protein HypD |
| M. smegmatis MC2 155 | MSMEG_2702 | hypD | e-104 | 51.52% (363) | hydrogenase expression/formation protein HypD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3981 | - | 1e-150 | 70.44% (362) | hydrogenase expression/formation protein HypD |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1857 | hypD | 1e-106 | 52.15% (372) | hydrogenase-forming protein, HypD |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_0227 | hypD | 1e-104 | 50.94% (371) | hydrogenase expression/formation protein HypD |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2361 | - | 0.0 | 87.43% (366) | hydrogenase expression/formation protein HypD |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2275|M.smegmatis_MC2_155 MKYLDEFRDPVAARTLVDRINRAATR------TWTMMEVCGGQTHSIIRN
Mvan_2361|M.vanbaalenii_PYR-1 MRYLDEFRDPAAAAVLVDAIRRRATK------PWTVMEVCGGQTHSIIRN
Mflv_3981|M.gilvum_PYR-GCK MKYLDEFSNPELAHRLIEQIEAVATR------RWSIMEVCGGQTHSIIRH
MMAR_1857|M.marinum_M MKFVDEFRDPAAARKLLTAIEHLAHQPGAGPEHFKFMEVCGGHTHTIYRH
TH_0227|M.thermoresistible__bu MRFVDEFRDPAAARKLLAAIEVLAAG-GEDGAPFKFMEVCGGHTHTIYRH
*:::*** :* * *: *. * :..******:**:* *:
MSMEG_2275|M.smegmatis_MC2_155 GIDQLLEGSVEFVHGPGCPVCVTPLEVIDRALEIAARDDVIFCSFGDMLR
Mvan_2361|M.vanbaalenii_PYR-1 GIDQLLAGAVEFIHGPGCPVCVTPLEMIDRALAIAARPDVIFCSFGDMLR
Mflv_3981|M.gilvum_PYR-GCK GIDQLLPDTVEMIHGPGCPVCVTPLEIIDKALDIASRPEVIFCSFGDMLR
MMAR_1857|M.marinum_M GIEHLLPDNVELVHGPGCPVCVIPMGRIDDAMWLAGQPDVIFTCFGDMMR
TH_0227|M.thermoresistible__bu GIEHLLPPTVELVHGPGCPVCVIPMGRIDDAMWLAAQPDVIFTSFGDMMR
**::** **::********* *: ** *: :*.: :*** .****:*
MSMEG_2275|M.smegmatis_MC2_155 VPGSHQDLFSVKARGGDVRIVYSPLDATRVAADNPDKQVVFFGVGFETTA
Mvan_2361|M.vanbaalenii_PYR-1 VPGSSQDLFGVRARGGDVRIVYSPLDATRIAADNPDKQVVFFGVGFETTA
Mflv_3981|M.gilvum_PYR-GCK VPGSEKDLFRVKSEGADVRVVYSPLDALTIARDNPDRQVVFFGIGFETTA
MMAR_1857|M.marinum_M VPGSDGSLLDAKARGADVRFVYSPLDALKVAIDNPDKQVVFFAIGFETTA
TH_0227|M.thermoresistible__bu VPGSNGSLLDAKARGADVRFVYSPLDALKIAVDNPDKRVVYFAIGFETTA
**** .*: .::.*.***.******* :* ****::**:*.:******
MSMEG_2275|M.smegmatis_MC2_155 PANAMAVVHAKRLGLKNFSMLVSHVLVPPAMTAILSSPSNRVQGFLAAGH
Mvan_2361|M.vanbaalenii_PYR-1 PANAMAVLHAQRLGLTNFSMLVSHVLVPPAMTAILSSPTNRVQGFLAAGH
Mflv_3981|M.gilvum_PYR-GCK PANAMTVYQAKKLGIENFSLLVSHVLVPPAIAAIMESPTCRVQAFLAAGH
MMAR_1857|M.marinum_M PSTAVTLVRARDLELPNFSVFCNHVTIVPPIKAILESPDLRLSGFIGPGH
TH_0227|M.thermoresistible__bu PSTAVTLLRATELGLRNFSVFCNHVTIVPPIKAILESPDLRLSGFLGPGH
*:.*::: :* * : ***:: .** : *.: **:.** *:..*:..**
MSMEG_2275|M.smegmatis_MC2_155 VCSVMGTSEYGPLVEKFDVPIVVTGFEPLDLLEGVRQLVDLLEAGTPELR
Mvan_2361|M.vanbaalenii_PYR-1 VCSVMGTSEYEPLVTEFGVPIVVTGFEPLDLLEGVRQVVELLEEGTPALR
Mflv_3981|M.gilvum_PYR-GCK VCTVMGTDEYPPLCDKYGTPIVVTGFEPLDILEGIRRTVIQLEAGRHELE
MMAR_1857|M.marinum_M VSTVVGNRPYRFVPEVYHKPLVVAGFEPLDILASVTMLLRQIREGRCEVE
TH_0227|M.thermoresistible__bu VSTVVGIRPYRFVPEVYRKPLVVAGFEPLDILAAVAMLLRQIREGRCEVE
*.:*:* * : : *:**:******:* .: : :. * :.
MSMEG_2275|M.smegmatis_MC2_155 NAYSRAVTAEGNVFAQQTLSEVFTVTDR-QWRGIGMIPRSGWTLSPQYAE
Mvan_2361|M.vanbaalenii_PYR-1 NAYPRAVSAEGNLVAQKTLAEVFAVTDR-QWRGIGMIPRSGWTLSPRYAE
Mflv_3981|M.gilvum_PYR-GCK NAYPRAVQDTGNPAAKAMLLDVFDVTDR-TWRGIGMIASSGWRLSPAYRH
MMAR_1857|M.marinum_M NQYKRVVPEEGNPAALALMGKVFALRPHFEWRGLGFISQSALRLSDDFAE
TH_0227|M.thermoresistible__bu NQYSRIVAPQGNPAALGMLARVFELRPHFEWRGLGFISQSALKLRDEFAD
* * * * ** * : ** : : ***:*:*. *. * : .
MSMEG_2275|M.smegmatis_MC2_155 FDAELRFGVGHLQVAESAECRSGEVLQGLLKPNECPAFGKTCTPRNPLGA
Mvan_2361|M.vanbaalenii_PYR-1 FDAERRFGVGHLQVAESSDCRSGEVLQGLLKPNECPAFGRTCTPRTPLGA
Mflv_3981|M.gilvum_PYR-GCK FDAEHRFAATDLHNEESAICRSGEVLQGLIKPHECTAFGTSCTPRNPLGA
MMAR_1857|M.marinum_M FDAELRFAMPGVRVADPKACQCGEVLKGVLKPWECKVFGTACTPETPIGT
TH_0227|M.thermoresistible__bu YDAERLFDMPGVRVADPKACQCGEVLKGVLRPWECKVFGTACTPETPIGT
:*** * :: :. *:.****:*:::* ** .** :***..*:*:
MSMEG_2275|M.smegmatis_MC2_155 TMVSSEGACAAYYQFRRLEAAAHV--------
Mvan_2361|M.vanbaalenii_PYR-1 TMVSSEGACAAYYQFRRLETAAHA--------
Mflv_3981|M.gilvum_PYR-GCK TMVSSEGACAAYYLYRRLEVTHA---------
MMAR_1857|M.marinum_M CMVSPEGACAAYYNFGRLHRDAVKLVGQSGRA
TH_0227|M.thermoresistible__bu CMVSSEGACAAYYNFGRLHRDAATLVGQAGRG
***.******** : **.