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AEAQWTVQGLLDLFDAEPTGDNMFTVQTGPAGEDERQVVEGTQILAASIVAAAKRFPDKSIRSVYTVFAR AVMVAAGPVELEIDVVSEGRSTATAVVTAKQNGKRCITTTVLADVPTGDVIRHHLPKPEVAGPAEAHLSP MPMAGRELRLVDVVDVNSPDEVGPPELYAWLHYDPIPDRDDLAKALIAYFTGHLGISTTMRAHEGIGTAQ AHLTVSTAPMTVSVSFHEPVTWGGWLLYTHESTQVGSGMSYVRGAVHTEEGELIASFTQDALIRPLRTTD TAIKEQSRL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3790 | - | - | 100% (290) | hypothetical protein Mflv_3790 |
| M. gilvum PYR-GCK | Mflv_2907 | - | 2e-17 | 26.43% (280) | acyl-CoA thioesterase |
| M. gilvum PYR-GCK | Mflv_1022 | - | 2e-11 | 25.82% (275) | acyl-CoA thioesterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2637c | tesB2 | 1e-06 | 27.52% (109) | acyl-CoA thioesterase II |
| M. tuberculosis H37Rv | Rv2605c | tesB2 | 1e-06 | 27.52% (109) | acyl-CoA thioesterase II |
| M. leprae Br4923 | MLBr_01278 | tesB | 8e-05 | 22.34% (282) | acyl CoA thioesterase II |
| M. abscessus ATCC 19977 | MAB_2638c | - | 2e-08 | 23.53% (255) | acyl-CoA thioesterase |
| M. marinum M | MMAR_0392 | - | 1e-124 | 73.87% (287) | hypothetical protein MMAR_0392 |
| M. avium 104 | MAV_5130 | - | 1e-127 | 76.39% (288) | hypothetical protein MAV_5130 |
| M. smegmatis MC2 155 | MSMEG_2997 | - | 1e-133 | 79.58% (289) | hypothetical protein MSMEG_2997 |
| M. thermoresistible (build 8) | TH_0539 | - | 1e-127 | 76.43% (280) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3249 | tesB2 | 2e-06 | 24.60% (252) | acyl-CoA thioesterase II TesB2 |
| M. vanbaalenii PYR-1 | Mvan_2604 | - | 1e-152 | 91.96% (286) | hypothetical protein Mvan_2604 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3790|M.gilvum_PYR-GCK ----------MAEAQWTVQGLLDLFDAEPTGDNMFTVQTG---PAGEDER
Mvan_2604|M.vanbaalenii_PYR-1 --MTTESAQTAGSVQWTVQGLLDLFDAEPAGEDTFTAQTG---PAGEDER
MSMEG_2997|M.smegmatis_MC2_155 MTTESTETAPGASVQWTLQMLLDLFEVEPAGENRFTAPTG---LAGADDR
TH_0539|M.thermoresistible__bu -------------------MLLDLFDVEPAGENRFTAPSG---IAGTDER
MMAR_0392|M.marinum_M ---MSALTTDSEQAQWSVDGLLELFQVRAEGVDRFTADTG---IAGHDGR
MAV_5130|M.avium_104 ---MSKVSQES--TEWTVQGLLDLFEVRPDGQDRFTADTAGDIGAGGDER
Mb2637c|M.bovis_AF2122/97 ------------------MSIEEILDLEQLEVNIYRGSVF---SPESGFL
Rv2605c|M.tuberculosis_H37Rv ------------------MSIEEILDLEQLEVNIYRGSVF---SPESGFL
MUL_3249|M.ulcerans_Agy99 ------------------MAIEEILDLEQLEVNIYRGSVF---SPESGFL
MLBr_01278|M.leprae_Br4923 -----MKRLWEKKTMSDFEELLAVLDLNRVADDLFIGSHP---SKNP---
MAB_2638c|M.abscessus_ATCC_199 ---------------------------------MFVGGHP---TVNP---
:
Mflv_3790|M.gilvum_PYR-GCK QVVEGTQILAASIVAAAKRFP-DKSIRSVYTVFARAVMVAAGPVELEIDV
Mvan_2604|M.vanbaalenii_PYR-1 QVVEGTQVLAQSIVAAAKRFP-DKSIRSVYSVFARAVMVGAGPVELEIDV
MSMEG_2997|M.smegmatis_MC2_155 QVVEGTQVLAQAIVAAAKRFP-DKSVRSVQAVFARAVLVGP-PVELDLDV
TH_0539|M.thermoresistible__bu QVVEGSQVLSAALVAAAKRFG-DKSIRSAYAVFARVVLVGP-PIEFDIDV
MMAR_0392|M.marinum_M QVVEGTQVVAQAIMAVASRFE-GKSVRSAHAVFCRAVIVGP-PLELVLDV
MAV_5130|M.avium_104 QVVEGTQVLAQAIVAVAKRFG-DKSVRSAHAVFSRAVAVGP-PIELVLDV
Mb2637c|M.bovis_AF2122/97 QRTFGGHVAGQSLVSAVRTVD-PRYMVHSLHGYFLRPGDAKERTVFLVER
Rv2605c|M.tuberculosis_H37Rv QRTFGGHVAGQSLVSAVRTVD-PRYMVHSLHGYFLRPGDAKERTVFLVER
MUL_3249|M.ulcerans_Agy99 QRTFGGHVAGQSLVSAVRTVD-PRYQVHSLHGYFLRSGDAQEPTVFLVER
MLBr_01278|M.leprae_Br4923 LRTFGGQLVAQSFVASSRTLIRDDLPPSAFSVHFINGGDTAKEIEFHVVR
MAB_2638c|M.abscessus_ATCC_199 PRTFGGQLMAQSLVASGRTVS-EKLSLAAISTHFVNGGDPELDIEFRVQR
. * :: . :::: . . : :
Mflv_3790|M.gilvum_PYR-GCK VSEGRSTATAVVTAKQNGKRCITTTVLADVPTGDVIRHHLPKPEVAGPAE
Mvan_2604|M.vanbaalenii_PYR-1 ISEGRSTASAVVTAKQNGKRCITTTVLADVPTDDVIRHHLPKPDVAGPAE
MSMEG_2997|M.smegmatis_MC2_155 VSEGRSTATAVVTASQNGKRCMTFTVFTDVPSADVIRHHLPRPDVAGPAD
TH_0539|M.thermoresistible__bu ISEGRSTTTAVVTASQNGKRCVTVTVLADVPSEDVIRHHLPRPQVVGPDE
MMAR_0392|M.marinum_M VHEGRSTATAIVAANQNGKRCLTVTVLADIPTGDVIKHHLPRPPVVAPAD
MAV_5130|M.avium_104 VAEGRSTATAVVAVHQNGRRCLSITVLADVPTGDVIRHQLPRPDVAGPAD
Mb2637c|M.bovis_AF2122/97 IRDGGSLCTRRVNAVQHG-ETIFSMAASFQTEQEGITHQDVMPAAPPPDG
Rv2605c|M.tuberculosis_H37Rv IRDGGSFCTRRVNAVQHG-ETIFSMAASFQTEQEGITHQDVMPAAPPPDG
MUL_3249|M.ulcerans_Agy99 TRDGGSFVTRRVNAVQHG-EVIFSMGASFQTAQNGISHQDAMPAAPPPDD
MLBr_01278|M.leprae_Br4923 LRDERRFANRRVDAIQDG-MLLSSAMASYMSGGCGLEHAVEPPEAAEPHT
MAB_2638c|M.abscessus_ATCC_199 LRDERNFANRRVDAVQGD-LLLSSALVSYLKDSPGLEHAVNPPVVADPET
: . * . * . : : : * * . *
Mflv_3790|M.gilvum_PYR-GCK AHLSPMPMAGRELRLVDVVD----------------VNSPDEVGPPELYA
Mvan_2604|M.vanbaalenii_PYR-1 ANASPMPMAGRELRLVDVVD----------------VNSPDEVGPPELYA
MSMEG_2997|M.smegmatis_MC2_155 ANVAHMPMTGRELRLVDVVD----------------VNSPDEVGPPELYA
TH_0539|M.thermoresistible__bu ANVCDMPMVGRQVKLVDIVD----------------VNSPDEVGPPEIHA
MMAR_0392|M.marinum_M ANVSEMPMAGRQLRLVDVVD----------------VNSPDEVGPPELYA
MAV_5130|M.avium_104 ANPSPMPMVGRELRLVDVVD----------------VNSPDEVGPPELYA
Mb2637c|M.bovis_AF2122/97 LPGLNSIKVFDDAGFRQFD------EWDVCIVPRERLRLLPGKASQQQVW
Rv2605c|M.tuberculosis_H37Rv LPGLNSIKVFDDAGFRQFD------EWDVCIVPRERLRLLPGKASQQQVW
MUL_3249|M.ulcerans_Agy99 LPGLRSVRVFDDAGFRQFE------EWDVRIVPRDLLAPLPGKASQQQVW
MLBr_01278|M.leprae_Br4923 RPPIGELLRGYEQIVQHFVNALQPVEWRYVNDPSWVMRNKGQRLAYNRVW
MAB_2638c|M.abscessus_ATCC_199 LPSIDEHLVGYEETVPMFVAALKPIEWRYDNDPAWVLKAKSQRLEHNRVW
: . . : :
Mflv_3790|M.gilvum_PYR-GCK WLHYDPIPDRDDLAKALIAYFTGHLGISTTMRAHEGIGTAQAHLTVSTAP
Mvan_2604|M.vanbaalenii_PYR-1 WLHYDPIPSRDDLAKALIAYFTGHLGISTTMRAHEGIGTAQAHLTVSTAP
MSMEG_2997|M.smegmatis_MC2_155 WLHYDPVPTRDDLAKALIAYFTGHLGISTTMRAHEGIGTAQAHLTVSTAP
TH_0539|M.thermoresistible__bu WLHYDPVPQRSDLAKALLAYFTGHLGISTTMRAHDGIGTAQSHVTVSTAP
MMAR_0392|M.marinum_M WLHYEPIPDRDDLAKALIAYFTGHLGISTTMRAHPGIGTSQAHLSVSTAP
MAV_5130|M.avium_104 WLHYDPIPTRDDLAKALLAYFTGHLGISTTMRAHPGIGTAQAHLTVSTAP
Mb2637c|M.bovis_AF2122/97 LRHRDPLPDDPVLHICALAYMSDLTLLGSAQVNHL---DVR--DQLQVAS
Rv2605c|M.tuberculosis_H37Rv LRHRDPLPDDPVLHICALAYMSDLTLLGSAQVNHL---DVR--DQLQVAS
MUL_3249|M.ulcerans_Agy99 FRHRDPLPDDPVLHICALAYMSDLTLLGSAQVTHL---AER--EHLQVAS
MLBr_01278|M.leprae_Br4923 VKALGALPNDPTLHTAAMLYSTDTTVLDSVITTHG---LSWGFDRIFAVS
MAB_2638c|M.abscessus_ATCC_199 MKTHAALPDDPVLHSAALVYSSDTTILDSIITTHG---LSWGYDRIFAAT
.:* * . : * :. :.: * : ...
Mflv_3790|M.gilvum_PYR-GCK MTVSVSFHEPVTWGGWLLYTHESTQVGSGMSYVRGAVHTEEGELIASFTQ
Mvan_2604|M.vanbaalenii_PYR-1 MTVSVSFHEPVRWDGWLLYSHESTQVGAGMSYVRGTVHTEEGELIASFTQ
MSMEG_2997|M.smegmatis_MC2_155 MTVNVSFHEPAAWDGWLLYSHESTQVGAGMSYVRGTVHTESGELIASFSQ
TH_0539|M.thermoresistible__bu MTISVSFHEPAGWDGWLLYSHESTQVGAGMSYVRGTVHTEAGELIASFTQ
MMAR_0392|M.marinum_M MTISVAFHEPVHWDGWLLYSHESTQVGAGMSYVRGTVHTEQGALIASFAQ
MAV_5130|M.avium_104 MSISVAFHEPVRWDGWLLYSHESTQVGAGMSYVRGTVHTEQGELLASFAQ
Mb2637c|M.bovis_AF2122/97 LDHAMWFMRPFRADEWLLYDQSSPSASGGRALTRGEIFTRSGEMVAAVMQ
Rv2605c|M.tuberculosis_H37Rv LDHAMWFMRPFRADEWLLYDQSSPSASGGRALTRGEIFTRSGEMVAAVMQ
MUL_3249|M.ulcerans_Agy99 LDHAMWFMRGFRADEWLLYDQSSPSAGGGRALTHGKIFTQGGELVAAVMQ
MLBr_01278|M.leprae_Br4923 ANHSVWFHRQVNFDDWVLYSTSSPVAADSRGLGTGHLFDRSGQLIATVVQ
MAB_2638c|M.abscessus_ATCC_199 INHSVWFHRPLRFDDWVLYATESPVASAGRGMGAGRYFDRDGALLASTIQ
: * . . *:** .*. .. . . * . . * ::*: *
Mflv_3790|M.gilvum_PYR-GCK DALIRPLRTTDTAIKEQSRL
Mvan_2604|M.vanbaalenii_PYR-1 DALIRPLRTTDTSIKHQSRL
MSMEG_2997|M.smegmatis_MC2_155 DAMIRPLRTVDTNISANARL
TH_0539|M.thermoresistible__bu DALIRPLRKIDAAIKEQARL
MMAR_0392|M.marinum_M EALIRPLRTSDTSIDARSRF
MAV_5130|M.avium_104 EALIRPLRTSDTAIDSRARF
Mb2637c|M.bovis_AF2122/97 EGLTRHRRGHRSVGQ-----
Rv2605c|M.tuberculosis_H37Rv EGLTRHRRGHRSVGQ-----
MUL_3249|M.ulcerans_Agy99 EGLTRYPSGYQPGEN-----
MLBr_01278|M.leprae_Br4923 EGVLKYFPASHR--------
MAB_2638c|M.abscessus_ATCC_199 EGIVKYFPGRS---------
:.: :