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IFGTRFVGRMAVASVLAIAALPVIVPTAGSQSCPDIDVVFARGTAESPGVGGVGQRFVDSLRAQAFPRTV GVHGVNYPASDNFTGGTVFKLNIVEGVRDEANHVRGVVSVCPNTKLVLGGYSQGAVVTALATSGVVPTGI ARGAAPLPLPAGVADNVAAVVLFGTPAGWSATKYGAADIDVGPAYASKALEFCAPGDAVCSGTVPTQDHG PHQQYGVNGMADRAATFAMGRLAELKPESPAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3177 | - | - | 100% (243) | cutinase |
| M. gilvum PYR-GCK | Mflv_1037 | - | 1e-63 | 51.11% (225) | cutinase |
| M. gilvum PYR-GCK | Mflv_4439 | - | 1e-49 | 44.00% (225) | cutinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3751 | cut5 | 3e-51 | 44.02% (234) | cutinase precursor CUT5 |
| M. tuberculosis H37Rv | Rv1984c | cfp21 | 9e-42 | 42.17% (230) | cutinase precursor CFP21 |
| M. leprae Br4923 | MLBr_00099 | - | 7e-07 | 25.51% (243) | hypothetical protein MLBr_00099 |
| M. abscessus ATCC 19977 | MAB_3272c | - | 7e-37 | 44.33% (194) | cutinase Cut1 |
| M. marinum M | MMAR_5251 | cut5 | 1e-51 | 44.05% (227) | cutinase, Cut5 |
| M. avium 104 | MAV_0369 | - | 2e-55 | 46.64% (223) | serine esterase cutinase |
| M. smegmatis MC2 155 | MSMEG_5878 | - | 2e-53 | 47.77% (224) | serine esterase, cutinase family protein |
| M. thermoresistible (build 8) | TH_1243 | - | 8e-53 | 44.49% (236) | PROBABLE CUTINASE |
| M. ulcerans Agy99 | MUL_4327 | cut5 | 3e-50 | 42.73% (227) | cutinase, Cut5 |
| M. vanbaalenii PYR-1 | Mvan_5793 | - | 4e-64 | 52.00% (225) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5878|M.smegmatis_MC2_155 ---------------MNVLKLLG-AALVAFG--------ALPVIP---AS
Mvan_5793|M.vanbaalenii_PYR-1 ---------------MKMSRVAGIAGAVALG--------ACSAVTGLGAP
TH_1243|M.thermoresistible__bu MGWVDMRVTELPNRSRSMFRLIGVISAFVLAGSMACGIGFVSAVMGVGSP
MMAR_5251|M.marinum_M ------------MRNATWTRRLAVGAATAVT-------ALVG--WGIRVP
MUL_4327|M.ulcerans_Agy99 ------------MRNATWTRRLAVGAATAVT-------ALVG--GGIRVP
Mb3751|M.bovis_AF2122/97 ------------MDVIRWARRLAVVAGTAAA-------VTTPGLLSAHVP
MAV_0369|M.avium_104 ---------------MSFQVRAALTVLTAAA-------ALCVA-PMPGAP
MAB_3272c|M.abscessus_ATCC_199 --------------------------------------------------
Rv1984c|M.tuberculosis_H37Rv ------------MTPRSLVRIVGVVVATTLA--------LVSAPAG--GR
Mflv_3177|M.gilvum_PYR-GCK -----------MIFGTRFVGRMAVASVLAIA------------ALPVIVP
MLBr_00099|M.leprae_Br4923 ---MVEKVPRKRHRVLAWTAALSMAAVVALAIVAVVILLRSAESPRSSLP
MSMEG_5878|M.smegmatis_MC2_155 PASA------------------QPCPDVEVVFARGTFEPPGVG-------
Mvan_5793|M.vanbaalenii_PYR-1 SAAA------------------QPCPDVEVVFARGTSEPPGVG-------
TH_1243|M.thermoresistible__bu TAAA------------------QPCPDVEVIFARGTDEPPGVG-------
MMAR_5251|M.marinum_M FAAA------------------EPCPDVEVLFARGTGEPPGIG-------
MUL_4327|M.ulcerans_Agy99 FVAA------------------EPCPDVEVLFARGTGEPPGIG-------
Mb3751|M.bovis_AF2122/97 MVSA------------------EPCPDVEVVFARGTGEPPGIG-------
MAV_0369|M.avium_104 AAGA------------------DPCPDVEVVFARGSGEPPGIG-------
MAB_3272c|M.abscessus_ATCC_199 ------------------------------MFARGTFEPPGVG-------
Rv1984c|M.tuberculosis_H37Rv AAHA------------------DPCSDIAVVFARGTHQASGLG-------
Mflv_3177|M.gilvum_PYR-GCK TAGS------------------QSCPDIDVVFARGTAESPGVG-------
MLBr_00099|M.leprae_Br4923 PGVLPIPSTAPHPRKPRPAFQDVSCPDVQLLVVPGTWESSLQDNPLDPVQ
:.. *: :.. .
MSMEG_5878|M.smegmatis_MC2_155 ---VMGQAFVDTLRAQAAPRSVDVYPVDYPASGDFGDR----IAFARTVV
Mvan_5793|M.vanbaalenii_PYR-1 ---GVGQAFVDALRAQAAPRTVGVYAVNYPAANNFTDR----AAFAGTVI
TH_1243|M.thermoresistible__bu ---GVGQAFIDELRPRIGDRSLSVYAVNYPASSNFGAG----IEFARTVV
MMAR_5251|M.marinum_M ---GIGGSFVAALRSDIGAKSLAVYAVDYPASSDFSS-----SDFPRTVI
MUL_4327|M.ulcerans_Agy99 ---GIGGSFVAALRSDIGAKSSAVYAIDYPASSDFSS-----SDFPRTVI
Mb3751|M.bovis_AF2122/97 ---SVGGLFVDALRSQVGAKSLGVYAVNYPASNDFAS-----SDFPKTVI
MAV_0369|M.avium_104 ---GIGQPFVDALRSQIGSRSLAVYAVKYPASTDFSN-----PDFPATVI
MAB_3272c|M.abscessus_ATCC_199 ---GTGESFVNALRARTKGKSVEVYPVEYPASLAFAT-----------AA
Rv1984c|M.tuberculosis_H37Rv ---DVGEAFVDSLTSQVGGRSIGVYAVNYPASDDYRA----------SAS
Mflv_3177|M.gilvum_PYR-GCK ---GVGQRFVDSLRAQAFPRTVGVHGVNYPASDNFTGG----TVFKLNIV
MLBr_00099|M.leprae_Br4923 FPDALLRNSTMTIGQQFPTSRVQTYTIPYTAQFHNPLSGDKQMTYNDSRA
: .: : *.*
MSMEG_5878|M.smegmatis_MC2_155 DGIADAASHVEATADTCPDTRIVVGGYSQGAVVAGFVTAADIPAEIPAEY
Mvan_5793|M.vanbaalenii_PYR-1 DGIRDASNRLQAMSVNCPNTRLVLGGFSQGAVVSGFTTSDTVPSSVPAAA
TH_1243|M.thermoresistible__bu DGIRDAADRVQTTAANCPDTRIVLGGYSQGAALAGYVTAAAVPEEVPVEF
MMAR_5251|M.marinum_M EGIRDASSHIESMAAKCPATREVLGGYSQGAAVAGYVTSASVPPGVPAAA
MUL_4327|M.ulcerans_Agy99 DGIRDASSHIESMAAKCPATREVLGGYSQGAAVAGYVTSASVPPGVPAAA
Mb3751|M.bovis_AF2122/97 DGIRDAGSHIQSMAMSCPQTRQVLGGYSQGAAVAGYVTSAVVPPAVPVQA
MAV_0369|M.avium_104 DGIRDASSHLESMVASCPNTREVLGGYSQGAAVAGYTTSAVVPPGVPASA
MAB_3272c|M.abscessus_ATCC_199 DGVIDASNRVKDVAARCPNTKIVMGGFSQGAAVVAYTTADAVPPGFELPE
Rv1984c|M.tuberculosis_H37Rv NGSDDASAHIQRTVASCPNTRIVLGGYSQGATVIDLSTSA----------
Mflv_3177|M.gilvum_PYR-GCK EGVRDEANHVRGVVSVCPNTKLVLGGYSQGAVVTALATSGVVPTGIARGA
MLBr_00099|M.leprae_Br4923 EGTRAMVQEMINVNNKCPLTSYVLVGFSQGAVIAGDITSDIGNGHGPVDD
:* .: ** * *: *:****.: *:
MSMEG_5878|M.smegmatis_MC2_155 RQY--------------IPDPMPAEVSDHVAAVVLIGKPSDQFMRDIG--
Mvan_5793|M.vanbaalenii_PYR-1 -----------------APTPLPPKVAEHVAAVVLFGAPSGSFMEKYG--
TH_1243|M.thermoresistible__bu RSY--------------VPEPMPREVADHVAAVVLFAQPSSALLQRYG--
MMAR_5251|M.marinum_M -----------------VPKPMAPDIADHVAAVTLFGTPSEQFLQHYG--
MUL_4327|M.ulcerans_Agy99 -----------------VPKPMAPDIADYVAAVTLFGTPSEQFLQHYG--
Mb3751|M.bovis_AF2122/97 -----------------VPAPMAPEVANHVAAVTLFGAPSAQFLGQYG--
MAV_0369|M.avium_104 -----------------VPPPMPPEVAKHVAAVTLFGTPSGQFLQKYH--
MAB_3272c|M.abscessus_ATCC_199 G----------------ITGPMPAEVADHVAAVALFGKPSSGFLQRIDNT
Rv1984c|M.tuberculosis_H37Rv ---------------------MPPAVADHVAAVALFGEPSSGFSSMLWGG
Mflv_3177|M.gilvum_PYR-GCK -----------------APLPLPAGVADNVAAVVLFGTPAGWSATKYG--
MLBr_00099|M.leprae_Br4923 DLVLGVTLIADGRRQQGVGNDIGPNPPGEGAEVTLHEVPVLSGLGMTMTG
: . * *.* *
MSMEG_5878|M.smegmatis_MC2_155 APPIVIGPRYVDKTLNLCAPGDTICDGAPAGGPSFAHALYNVNGMMGQA-
Mvan_5793|M.vanbaalenii_PYR-1 APAVTVGPLYADRTVELCAAGDSICDGAPNGGPNLAHALYPVNGMVGQG-
TH_1243|M.thermoresistible__bu APPIAIGSVYQDKTLELCTEGDTICNGVADVMPTFAHVTYTWNGMPAEG-
MMAR_5251|M.marinum_M APPITIGPLYQPRTVELCASGDPVCS---GGNDAAAHALYAVNGMTGQG-
MUL_4327|M.ulcerans_Agy99 APPITIGPLYQPRTIELCASGDPVCS---GGNDAAAHALYAVNGMTGQG-
Mb3751|M.bovis_AF2122/97 APPIAIGPLYQPKTLQLCADGDSICG---DGNSPVAHGLYAVNGMVGQG-
MAV_0369|M.avium_104 APPLAIGPLYQPKTLQLCAVGDPICGTG-GGNDLAAHTSYPVNGMTNQA-
MAB_3272c|M.abscessus_ATCC_199 APPINIGHLYVAKTMDMCVPEDPICS--PDGSDNAAHGSYGDNGMTSQA-
Rv1984c|M.tuberculosis_H37Rv GSLPTIGPLYSSKTINLCAPDDPICT---GGGNIMAHVSYVQSGMTSQA-
Mflv_3177|M.gilvum_PYR-GCK AADIDVGPAYASKALEFCAPGDAVCSGTVPTQDHGPHQQYGVNGMADRA-
MLBr_00099|M.leprae_Br4923 ARPGGFG-VLHSRTNEICAPGDLICAAP-AEAFSVANLPATLNTLASGAG
. .* :: ::*. * :* .: . : .
MSMEG_5878|M.smegmatis_MC2_155 ----AQYVIDRL-----------------------------
Mvan_5793|M.vanbaalenii_PYR-1 ----ASYAAGRL-----------------------------
TH_1243|M.thermoresistible__bu ----AAFAADRL-----------------------------
MMAR_5251|M.marinum_M ----ADFAAHHL-----------------------------
MUL_4327|M.ulcerans_Agy99 ----ADFAAHHL-----------------------------
Mb3751|M.bovis_AF2122/97 ----ANFAASRL-----------------------------
MAV_0369|M.avium_104 ----AQYVFSHL-----------------------------
MAB_3272c|M.abscessus_ATCC_199 ----ADFAARQINSPTDTVSAAG------------------
Rv1984c|M.tuberculosis_H37Rv ----ATFAANRLDHAG-------------------------
Mflv_3177|M.gilvum_PYR-GCK ----ATFAMGRLAELKPESPAS-------------------
MLBr_00099|M.leprae_Br4923 QPIHAMYATAQFWDLDGAPATVWTLNWVHRLIEGAPHPKHG
* :. ::