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PYVLPNDGETVGVGQPIAIRFDENITNRVAAQQAITVTTNPPVEGAFYWLSNREVRWRPAEYWEPGTKVE VSVKAYGVDFGDGLFGQDDVTTRFTIGDQIIATADDATKTMTVRRNGEVVKTMPISMGKAKTPTDNGAYI VGDRYSFLVMDSSTYGVPVNSPDGYRTEVEWATQMSYSGIYVHSAPWSVGSQGIANVSHGCLNVNPANAR WFYDNTRRGDIVEVINTTGPTLSGTDGLGDWNIPWEQWKAGNANV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2844 | - | - | 100% (256) | ErfK/YbiS/YcfS/YnhG family protein |
| M. gilvum PYR-GCK | Mflv_0904 | - | e-151 | 97.66% (256) | ErfK/YbiS/YcfS/YnhG family protein |
| M. gilvum PYR-GCK | Mflv_2542 | - | e-126 | 78.52% (256) | ErfK/YbiS/YcfS/YnhG family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2547c | lppS | 1e-118 | 72.83% (254) | lipoprotein LppS |
| M. tuberculosis H37Rv | Rv2518c | lppS | 1e-118 | 72.83% (254) | lipoprotein LppS |
| M. leprae Br4923 | MLBr_00426 | lppS | 1e-118 | 71.48% (256) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_1530 | - | 1e-114 | 70.08% (254) | lipoprotein LppS |
| M. marinum M | MMAR_3872 | lppS | 1e-116 | 72.16% (255) | lipoprotein LppS |
| M. avium 104 | MAV_1661 | - | 1e-121 | 74.51% (255) | ErfK/YbiS/YcfS/YnhG family protein |
| M. smegmatis MC2 155 | MSMEG_4745 | - | 1e-126 | 80.08% (256) | ErfK/YbiS/YcfS/YnhG family protein |
| M. thermoresistible (build 8) | TH_1098 | lppS | 1e-125 | 77.34% (256) | PROBABLE CONSERVED LIPOPROTEIN LPPS |
| M. ulcerans Agy99 | MUL_3804 | lppS | 1e-116 | 71.76% (255) | lipoprotein LppS |
| M. vanbaalenii PYR-1 | Mvan_3651 | - | 1e-150 | 97.27% (256) | ErfK/YbiS/YcfS/YnhG family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_00426|M.leprae_Br4923 --------MGTATRRVQPKAWRALLTLLVISVVMP-GVACN-RGGGNVPV
MAV_1661|M.avium_104 ---------------------------------MG-AVACG-GGHTAAPP
Mb2547c|M.bovis_AF2122/97 -----MPKVGIAAQAGRTRVRRAWLTALMMTAVMIGAVACG-SGRGPAPI
Rv2518c|M.tuberculosis_H37Rv -----MPKVGIAAQAGRTRVRRAWLTALMMTAVMIGAVACG-SGRGPAPI
MMAR_3872|M.marinum_M --------MAPLSRR------RSWLAAILIPVAVL-AVACGGSSATPTAT
MUL_3804|M.ulcerans_Agy99 -------MMAPLSRR------RSWLAAILIPVAVL-AVACGGSSATPTAT
MAB_1530|M.abscessus_ATCC_1997 --------MTQGRPRLHAGARRRWVATLALPVVAM-AVLAGCAGATTQEP
Mflv_2844|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3651|M.vanbaalenii_PYR-1 MPQIGCPLPFRATTH-----WLRTTVLAVAVLLIA--TACTSSPAAAPTP
MSMEG_4745|M.smegmatis_MC2_155 --------MIRPRRS-----LFRSAVVAMVPALLFGLMACGKDEQDGPAP
TH_1098|M.thermoresistible__bu --------MTRPRWR-----SRWWLITGLLSVVVLALSACSGG-GASDQP
MLBr_00426|M.leprae_Br4923 NVIGDKGTPFADLLVPKLTASVTDGAVGVNVDMPVTVTVADGVLAAVTMI
MAV_1661|M.avium_104 KVIFDKGTPFADLLVPKLTASVSDGAVGVTVDAPVTVSVADGVLASVTMV
Mb2547c|M.bovis_AF2122/97 KVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLAAVTMV
Rv2518c|M.tuberculosis_H37Rv KVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLAAVTMV
MMAR_3872|M.marinum_M KVIENKGTPFADLLVPKLTASVTDGAVGVTVDAPVTVSVSDGVLAAVTMV
MUL_3804|M.ulcerans_Agy99 KVIENKGTPFADLLVPKLTASVTDGAVGVTVDAPVTVSVSDGVLAAVTMV
MAB_1530|M.abscessus_ATCC_1997 PKVIDKATPYADLLVPKLAMSVKDGAVGVAVDAPVTVTAGEGVLGSVTMV
Mflv_2844|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3651|M.vanbaalenii_PYR-1 DVITDKGTPYADLLVPKLEASVTDGAIGVAVDAPVTVTAGDGVLGQVSLT
MSMEG_4745|M.smegmatis_MC2_155 -VIADKGTPFGDLLVPRVNASVTDGAVGVTVESPVTVTAENGVLGGVSMT
TH_1098|M.thermoresistible__bu KVITDKGTPYGDLLVPRVTASVTDKAVGVPVDEPVTVSAENGVLGAVTMV
MLBr_00426|M.leprae_Br4923 NDNGRMINGQFSPDGLRWSTTEPLGFNRCYTLSAKALGLGGVVNRQMTFQ
MAV_1661|M.avium_104 NENGRSISGQLSPDGLRWSTTEQLGYNRRYTLTAKATGLGGAASKQMTFE
Mb2547c|M.bovis_AF2122/97 NDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATRQLTFQ
Rv2518c|M.tuberculosis_H37Rv NDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATRQLTFQ
MMAR_3872|M.marinum_M NESGKSISGKLSSDGLHWSTDEPLGYNRRYTLNAKALGLGGAATRQMTFQ
MUL_3804|M.ulcerans_Agy99 NESGKSISGKLSFDGLHWSTDEPLGYNRRYTLNAKALGLGGAATRQMTFQ
MAB_1530|M.abscessus_ATCC_1997 NSDGKEIAGEIGPDGVTWTTTEPLGYDKQYTINADARGLGGVARANATFR
Mflv_2844|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3651|M.vanbaalenii_PYR-1 NEAGELVDGQLSPDGVTWSSAEPLGYNKQYTLQAHAQGLGGTTSTSATFE
MSMEG_4745|M.smegmatis_MC2_155 DESGSPVAGTLSPDGLTWSTTDPLDYNEQYTLVAQSLGLGGVTNRRIQFE
TH_1098|M.thermoresistible__bu NEQGRTVEGEFSEDGVSWSTTEPLGYNRQYTITAQSLGLGGVTTREMTFE
MLBr_00426|M.leprae_Br4923 TSSPAHLTMPYVNPGNGEIVGIGEPVAIRFDENIANRLAAQKAITITANP
MAV_1661|M.avium_104 TSSPAHLTMPYVSPADGEVVGVGEPVAIRFDENIANRAAAQKAITITTNP
Mb2547c|M.bovis_AF2122/97 TSSPAHLTMPYVMPGDGEVVGVGEPVAIRFDENIADRGAAEKAIKITTNP
Rv2518c|M.tuberculosis_H37Rv TSSPAHLTMPYVMPGDGEVVGVGEPVAIRFDENIADRGAAEKAIKITTNP
MMAR_3872|M.marinum_M TSSPAHLTMPYVSPADGEVVGVGEPVAIRFDENIANRLAAEKAIKITTKP
MUL_3804|M.ulcerans_Agy99 TSSPAHLTMPYVSPADGEVVGVGEPVAIRFDENIANRLAAEKAIKITTKP
MAB_1530|M.abscessus_ATCC_1997 TQSPDNMTMPYVMPGDGEVVGVGQTVAIRFDENIPNRAAAEKAIKITTNP
Mflv_2844|M.gilvum_PYR-GCK --------MPYVLPNDGETVGVGQPIAIRFDENITNRVAAQQAITVTTNP
Mvan_3651|M.vanbaalenii_PYR-1 THSPENLTMPYVLPNDGETVGVGQPIAIRFDENITNRVAAQQAITVTTNP
MSMEG_4745|M.smegmatis_MC2_155 THSPQNLTMPYVLPNNGEVVGVGQPIAIRFDENISDRVAAQRAITVKTTP
TH_1098|M.thermoresistible__bu THSPANLTMPYVVPSPGEVVGVGQPVAVRFDENIPNRAAAERAIKVTTNP
**** * ** **:*:.:*:******.:* **::**.:.:.*
MLBr_00426|M.leprae_Br4923 PVEGAFYWLNNREVRWRPEHFWKSGTAVDVAVNTYGVDLGEGMFGEDNVK
MAV_1661|M.avium_104 PVEGAFYWLNNREVRWRPEHFWKSGTVIDVAVNTYGVDLGDGMFGEDNVK
Mb2547c|M.bovis_AF2122/97 PVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDLGEGMFGEDNVQ
Rv2518c|M.tuberculosis_H37Rv PVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDLGEGMFGEDNVQ
MMAR_3872|M.marinum_M AVEGAFYWLNNREVRWRPEHFWKSGTSVDVAVNTYGVDLGEGMFGEDNVK
MUL_3804|M.ulcerans_Agy99 AVEGAFYWLNNREVRWRPEHFWKSGTSVDVAVNTYGVDLGEGMFGEDNVK
MAB_1530|M.abscessus_ATCC_1997 PVEGAFYWLNNREVRWRPESFWDSGTSVDVKVNTYGVNLGDGVFGQDNVA
Mflv_2844|M.gilvum_PYR-GCK PVEGAFYWLSNREVRWRPAEYWEPGTKVEVSVKAYGVDFGDGLFGQDDVT
Mvan_3651|M.vanbaalenii_PYR-1 PVEGAFYWLSNREVRWRPAEYWEPGTHVEVSVEAYGVDFGDGLFGQEDVT
MSMEG_4745|M.smegmatis_MC2_155 PVEGAFYWLNNREVRWRPAEYWKPGTTVDVQVNTYGVELGDGLYGQDNVE
TH_1098|M.thermoresistible__bu PVEGAFYWLNNREVRWRPASYWKPGTTVEVEVNTYGVDLGDGLFGQRNTK
.********.******** :*..** ::* *::***::*:*::*: :.
MLBr_00426|M.leprae_Br4923 THFTIGDEVFATADDATKMLTVRVNGEVVKIMPTSMGKDSTPTANGIYIV
MAV_1661|M.avium_104 THFTIGDEVISTADDTTKTVTVRVNGEVVKTMPTSMGKDSTPTANGIYIV
Mb2547c|M.bovis_AF2122/97 THFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGKDSTPTANGIYIV
Rv2518c|M.tuberculosis_H37Rv THFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGKDSTPTANGIYIV
MMAR_3872|M.marinum_M THFTIGDEVIATADDNTKMLTIRVNGEVVKTMPTSMGKDSTPTANGIYIV
MUL_3804|M.ulcerans_Agy99 THFTIGDEVIATADDNTKMLTILVNGEVVKTMPTSMGKDSTPTANGIYIV
MAB_1530|M.abscessus_ATCC_1997 SHFTIGDAVISRVDDTNKILNIERNGEIIKTMPTSMGKDKAPTNNGTYII
Mflv_2844|M.gilvum_PYR-GCK TRFTIGDQIIATADDATKTMTVRRNGEVVKTMPISMGKAKTPTDNGAYIV
Mvan_3651|M.vanbaalenii_PYR-1 TRFTIGDHIIATADDATKTMTVRRNGEVVKTMPISMGKAKTPTDNGAYII
MSMEG_4745|M.smegmatis_MC2_155 THFKIGDEVIAVADDNTKTLTVRRNGEVVKTMPISMGKNSTPTNNGVYII
TH_1098|M.thermoresistible__bu THFTIGDEVISTVDDNTKTLTVRRNGEVVKTMPVSMGKDSTPTNNGVYIV
::*.*** ::: .** .* :.: ***::* ** **** .:** ** **:
MLBr_00426|M.leprae_Br4923 GARFKHIIMDSSTYGVPVNSPNGYRADVDWATQLSYSGVFLHSAPWSVGA
MAV_1661|M.avium_104 GARFKHIIMDSSTYGVPVNSPNGYRTEVDWATQMSYSGVFVHSAPWSVGA
Mb2547c|M.bovis_AF2122/97 GSRYKHIIMDSSTYGVPVNSPNGYRTDVDWATQISYSGVFVHSAPWSVGA
Rv2518c|M.tuberculosis_H37Rv GSRYKHIIMDSSTYGVPVNSPNGYRTDVDWATQISYSGVFVHSAPWSVGA
MMAR_3872|M.marinum_M GARFKHIIMDSSTYGVPVNSPNGYRTDVNWATQLSYSGVYVHSAPWSVGA
MUL_3804|M.ulcerans_Agy99 GARFKHIIMDSSTYGVPVNSPNGYRTDVNWATQLSYSGVYVHSAPWSVGA
MAB_1530|M.abscessus_ATCC_1997 GERFKDLIMDSSTYGVAVNSPDGYRTKVQYATQMSYSGIYVHAAPWSVGA
Mflv_2844|M.gilvum_PYR-GCK GDRYSFLVMDSSTYGVPVNSPDGYRTEVEWATQMSYSGIYVHSAPWSVGS
Mvan_3651|M.vanbaalenii_PYR-1 GDRYSFLVMDSSTYGVPVNSPDGYRTEVEWATQMSYSGIYVHSAPWSVGS
MSMEG_4745|M.smegmatis_MC2_155 GDRYEHLVMDSSTYGVPVNSPNGYRTEVDYATQMSYSGIYVHGAPWSVGS
TH_1098|M.thermoresistible__bu GDKRAHMVMDSSTYGVPVNSPNGYRTEVDWAVQMSYSGIYVHSAPWSVGS
* : ::********.****:***:.*::*.*:****:::*.******:
MLBr_00426|M.leprae_Br4923 QGHTNTSHGCLNVSPSNAQWFYDHVKRGDIVEVVNTVGDTLPGAEGLGDW
MAV_1661|M.avium_104 QGHTNTSHGCLNVSPSNAEWFYDHSKSGDIVEVVHTVGPTLPGTEGLGDW
Mb2547c|M.bovis_AF2122/97 QGHTNTSHGCLNVSPSNAQWFYDHVKRGDIVEVVNTVGGTLPGIDGLGDW
Rv2518c|M.tuberculosis_H37Rv QGHTNTSHGCLNVSPSNAQWFYDHVKRGDIVEVVNTVGGTLPGIDGLGDW
MMAR_3872|M.marinum_M QGHTNTSHGCLNVSPSNAEWFYDHIKTGDIVEVVNTVGGTLPGTEGLGDW
MUL_3804|M.ulcerans_Agy99 QGHTNTSHGCLNVSPSNAEWFYDHIKTGDIVEVVNTVGGTLPGTEGLGDW
MAB_1530|M.abscessus_ATCC_1997 QGRTNTSHGCLNVSTANAKWFYENTKRGDVVIVSNTVGPVLPGTEGLGDW
Mflv_2844|M.gilvum_PYR-GCK QGIANVSHGCLNVNPANARWFYDNTRRGDIVEVINTTGPTLSGTDGLGDW
Mvan_3651|M.vanbaalenii_PYR-1 QGIANVSHGCLNVNPANARWFYDNTRRGDIVEVINTTGATLSGTDGLGDW
MSMEG_4745|M.smegmatis_MC2_155 QGYSNVSHGCLNVSTANARWFYENTKRGDIVEVRNTVGSLLPGTDGLGDW
TH_1098|M.thermoresistible__bu QGYSNVSHGCINVSPSNAKWFYENSKRGDIIEVVNTVGTVLPGTDGLGDW
** :*.****:**..:**.***:: : **:: * :*.* *.* :*****
MLBr_00426|M.leprae_Br4923 NIPWEQWKAGNANI-
MAV_1661|M.avium_104 NIPWSQWKAGNANT-
Mb2547c|M.bovis_AF2122/97 NIPWDQWRAGNAKA-
Rv2518c|M.tuberculosis_H37Rv NIPWDQWRAGNAKA-
MMAR_3872|M.marinum_M NIPWEQWRAGNANA-
MUL_3804|M.ulcerans_Agy99 NIPWEQWRAGNANA-
MAB_1530|M.abscessus_ATCC_1997 NIPWAQWKAGNARQQ
Mflv_2844|M.gilvum_PYR-GCK NIPWEQWKAGNANV-
Mvan_3651|M.vanbaalenii_PYR-1 NIPWEQWKAGNANL-
MSMEG_4745|M.smegmatis_MC2_155 NIPWEQWRAGNASI-
TH_1098|M.thermoresistible__bu NIPWEQWKAGNANV-
**** **:****