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MMTTALWLLLYGGALAWLAPPVLRRMTGQGISPHMGVAAWLITVAATLAAWLVAVSMVIGATADSIRTGA VVTLCLELFGFSEHTPMAGRIGSVALIGMGTLTLGFGGLRMSRSLSRLRARSHEHAHAARIIGRPTGHPN VVVVDADRPAAYCVGGRLNTIIVTSAAIKTLNRSQLKAVLAHENAHISGRHHHILMGLRALAVTLPRLPL FATARHSVAELLEMCADDTAARRVGTRPLLAGLIALAGHQPPVHEGLAAAGTAVVARAERLVTPTRRHVR WRHRICLAAAIIAMLATPALIQLLCHH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2841 | - | - | 100% (307) | peptidase M48, Ste24p |
| M. gilvum PYR-GCK | Mflv_0897 | - | e-132 | 74.51% (306) | hypothetical protein Mflv_0897 |
| M. gilvum PYR-GCK | Mflv_2815 | - | 7e-60 | 43.79% (306) | peptidase M48, Ste24p |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1876c | - | 1e-19 | 28.35% (321) | hypothetical protein Mb1876c |
| M. tuberculosis H37Rv | Rv1845c | - | 1e-19 | 28.35% (321) | hypothetical protein Rv1845c |
| M. leprae Br4923 | MLBr_02064 | - | 4e-21 | 28.30% (318) | integral membrane protein |
| M. abscessus ATCC 19977 | MAB_4859 | - | 8e-53 | 37.95% (303) | hypothetical protein MAB_4859 |
| M. marinum M | MMAR_5059 | - | 3e-64 | 45.78% (308) | peptidase M48 like- protein |
| M. avium 104 | MAV_2870 | - | 1e-19 | 30.12% (249) | integral membrane protein |
| M. smegmatis MC2 155 | MSMEG_3631 | - | 1e-18 | 27.14% (280) | integral membrane protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4135 | - | 9e-61 | 44.48% (308) | peptidase M48 like- protein |
| M. vanbaalenii PYR-1 | Mvan_3654 | - | 1e-133 | 75.82% (306) | hypothetical protein Mvan_3654 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1876c|M.bovis_AF2122/97 --MSALAFTILAVLLAGPTPALLARATWPLRAPRAAMVLWQAIALAAVLS
Rv1845c|M.tuberculosis_H37Rv --MSALAFTILAVLLAGPTPALLARATWPLRAPRAAMVLWQAIALAAVLS
MLBr_02064|M.leprae_Br4923 --MSALAFTILAVLLVGPTPTLVARSTWPLRAPRAAMVLWQTIALAAALS
MAV_2870|M.avium_104 --MSALAFTILAVLLTGPVPAMLARARWPLRAPRAAMVLWQAVALAAVLS
MSMEG_3631|M.smegmatis_MC2_155 --MSALAFTLVALALVGPVPAMLARASWPLRAPRAAIVLWQSIALAAVLS
Mflv_2841|M.gilvum_PYR-GCK MMTTALWLLLYGGALAWLAPPVLRRMTGQGISPHMGVAAWLITVAATLAA
Mvan_3654|M.vanbaalenii_PYR-1 -MTTALWLVLYGAVLAWLAPPVLRRLTGGGVSPSMGVAAWLATVAAVLAA
MMAR_5059|M.marinum_M -MNAALLLFAYASALIWVGPVLLRRVTGTGVHPRLAVASWLSAVFAAIAA
MUL_4135|M.ulcerans_Agy99 -MNAALLLFAYASALIWVGPVLLRRVTGTGVHPRLAVASWLSAVFAAIAA
MAB_4859|M.abscessus_ATCC_1997 -MSIAVCLLLYSVAVLIFGPRLLRRLTRTGYAPRLAITAWLAAIVSVLGT
*: : . : * :: * * .:. * :. :
Mb1876c|M.bovis_AF2122/97 SFSAGIAIASRLLMPGPDGRPTTSFVGAAGRLGWPLWAAYITVFALTVLV
Rv1845c|M.tuberculosis_H37Rv SFSAGIAIASRLLMPGPDGRPTTSFVGAAGRLGWPLWAAYITVFALTVLV
MLBr_02064|M.leprae_Br4923 TFSAGIAIASRVLMPGPDGRLTASVIGAAGRLGWPLWAAYVAAFALTVLV
MAV_2870|M.avium_104 AFSAGIAIATRVLVPGPDGRPTTSILGAEGRLGWPLWTAYIGVFALTVLV
MSMEG_3631|M.smegmatis_MC2_155 AFSAGIAIASRLFVPGADGRPTATITSEIDVLGWPLWLLYVVVFSLTLFI
Mflv_2841|M.gilvum_PYR-GCK WLVAVSMVIGATADSIRTG---AVVTLCLELFGFSEHTPMAGRIG---SV
Mvan_3654|M.vanbaalenii_PYR-1 WLAAVVLVVNATSNSILDG---SVVTLCLELFGFSDHTPLAGRLG---SI
MMAR_5059|M.marinum_M WVGALVFLGAAVLDSIWRH---RALALCLKELGLAGELGLPRGIASALAV
MUL_4135|M.ulcerans_Agy99 WVGALVSLGAAVLDSIWRH---RALALCVKELGLAGELGLPRGIASALAV
MAB_4859|M.abscessus_ATCC_1997 WISAAALIVIDVVRHWNSP---AVVLAACAARLHAMLIGQAGAAAQVGLL
. * : . . . :
Mb1876c|M.bovis_AF2122/97 GARLAVAVVRVATATRRRRAHHRMVVDLVGVGHNGALAQPCARARDLRVL
Rv1845c|M.tuberculosis_H37Rv GARLAVAVVRVATATRRRRAHHRMVVDLVGVGHNGALAQPCARARDLRVL
MLBr_02064|M.leprae_Br4923 GARLIVAIVRVAIATRRRRAHHRMVVDLVGVGHNAALAQPCARARDLRVL
MAV_2870|M.avium_104 GARLMVAVVRVAIANRRRRAHHRMVVDLVGMGHGAALSQPCSRTRDLRVL
MSMEG_3631|M.smegmatis_MC2_155 GARLCVAIVQVGVATRRRRAHHRMMVDLLSKSRDAVPAHLRTPASGLRIL
Mflv_2841|M.gilvum_PYR-GCK ALIGMGTLTLGFGGLRMSRSLSRLRARSHEHAHAARIIGRPTGHPNVVVV
Mvan_3654|M.vanbaalenii_PYR-1 ALIGGGLLTSAVVALRLGRCLAGLRTRSHEHAHAARIVGRPTDHPHVVVV
MMAR_5059|M.marinum_M GVLSTGAVATVIACWRMGRQLRRQRSASRLHAATARTIGGASDWPGVVVV
MUL_4135|M.ulcerans_Agy99 GVLSTGAVATVIVCWRMGRQLRGQRSASRLHAATARTIGGVSDWPGVVVV
MAB_4859|M.abscessus_ATCC_1997 ALSAAGSIAAPALGVRLARTLIRLRDTAHEHAYAVHMVGRRTAEGDVMVL
. :. * * . : : ::
Mb1876c|M.bovis_AF2122/97 DVAQPLAYCLPGVRS-RVVVSEGTLTALADAEVAAILTHERAHLRARHDL
Rv1845c|M.tuberculosis_H37Rv DVAQPLAYCLPGVRS-RVVVSEGTLTALADAEVAAILTHERAHLRARHDL
MLBr_02064|M.leprae_Br4923 EVAQPLAYCLPGVRS-RVVVSEGALTKLNDTEVTAILTHERAHLRARHDL
MAV_2870|M.avium_104 DVPQPLAYCLPGVRS-RVVVSEGTLSTLADAEVSAILTHERAHLRARHDL
MSMEG_3631|M.smegmatis_MC2_155 DVAQPLAYCLPGVRS-RVVVSEGTLDTLSPDEVDAILTHERAHLRARHDL
Mflv_2841|M.gilvum_PYR-GCK DADRPAAYCVGGRLN-TIIVTSAAIKTLNRSQLKAVLAHENAHISGRHHH
Mvan_3654|M.vanbaalenii_PYR-1 EADLPAAYCVIGRPH-AIVVTSAAVKSLNRAQLKAVLAHENAHLTGHHHH
MMAR_5059|M.marinum_M PAPQPAAYCVTGRPNSVIVVTSGALGRLDEPQLAAVLAHEYAHLASRHHD
MUL_4135|M.ulcerans_Agy99 PAPQPAAYCVTGRPNSVIVVTSGALGRLDEPQLAAVLAHEYAHLASRHHD
MAB_4859|M.abscessus_ATCC_1997 EAPEAAAYCVAGRPS-AIVLTTGALAVLDDAQVAAILAHERAHLAGHHPQ
. . ***: * :::: .:: * :: *:*:** **: .:*
Mb1876c|M.bovis_AF2122/97 VLEAFTAVHAAFPRLVRSANALGAVQLLVELLADDAAVRAAGRTPLARAL
Rv1845c|M.tuberculosis_H37Rv VLEAFTAVHAAFPRLVRSANALGAVQLLVELLADDAAVRAAGRTPLARAL
MLBr_02064|M.leprae_Br4923 VLEAFTAVHAAFPRLVRSSAALSAVRLLVELLADDAAVRAAGRTPLARAL
MAV_2870|M.avium_104 VLEAFTAVHAAFPRLVRSANALGAVQLLVELLADDAAVRAAGRAPLARAL
MSMEG_3631|M.smegmatis_MC2_155 VLEMFTAVHAAFPRFVRSASALDAVRLLIELLADDAAVRIAGPTPLARAL
Mflv_2841|M.gilvum_PYR-GCK ILMGLRALAVTLPRLPLFATARHSVAELLEMCADDTAARRVGTRPLLAGL
Mvan_3654|M.vanbaalenii_PYR-1 ILMVLRALAATLPHLPLFACAHQAVAELLEMCADDTAARRVGTRPLLAGL
MMAR_5059|M.marinum_M LLMALRALASSLPRLPLFAAAAKVVADLLEMCADDVAVRSHGKMALLRGL
MUL_4135|M.ulcerans_Agy99 LLMALRALASSLPRLPLFAAAAKVVADLLEMCADDVAVRSHGKMALLRGL
MAB_4859|M.abscessus_ATCC_1997 LVSVLRALADVFPRVRLMTDGSAQISRLLEMCADDSAARHHGRGVLLSGL
:: : *: :*:. : . : *:*: *** *.* * * .*
Mb1876c|M.bovis_AF2122/97 VACASGRAP-SGALAVGGPSTVLRVRRLSGRGNSAVLSAAAYLAAAAVLV
Rv1845c|M.tuberculosis_H37Rv VACASGRAP-SGALAVGGPSTVLRVRRLSGRGNSAVLSAAAYLAAAAVLV
MLBr_02064|M.leprae_Br4923 VACASGQAP-SGALAAGGNTTVLRVRRLSGRSNSAVVSAAAYLAAAIVLL
MAV_2870|M.avium_104 VACASGRAP-SGALAAGGPSTVVRVRRLGGRGNSPLLSAAAYLAAAAVFV
MSMEG_3631|M.smegmatis_MC2_155 VTCAAGRTP-SGALAAGGPTTVIRVRRLGGKPNSLTLSVIAYLAAVAILV
Mflv_2841|M.gilvum_PYR-GCK IALAGHQPPVHEGLAAAGTAVVARAERLVTPTRRHVRWRHRICLAAAIIA
Mvan_3654|M.vanbaalenii_PYR-1 LALAGHRPPVTEGLAAAAMAVITRAERLVTPTRRHVQWRHRALLVAAIAT
MMAR_5059|M.marinum_M LALTEGPAMAPAALGAANTATVARAERLAISVSRRSWWQERLMLWATIGL
MUL_4135|M.ulcerans_Agy99 LALTEGPAMAPVALGAANTATVARAERLAISVSRRSWWQERLMLWATSGL
MAB_4859|M.abscessus_ATCC_1997 MDLAGTVP--AAAVGAANVAVLDRAERLLTPPEPPARAWARIALTMCVAA
: : . .:... :.: *..**
Mb1876c|M.bovis_AF2122/97 VPTVALAVPWLTQLQRLFIA--
Rv1845c|M.tuberculosis_H37Rv VPTVALAVPWLTQLQRLFIA--
MLBr_02064|M.leprae_Br4923 VPTVALAVPWLTELQRLFNI--
MAV_2870|M.avium_104 VPTVALAVPWLTELERLLNL--
MSMEG_3631|M.smegmatis_MC2_155 VPTVAVAVPWLTELHRLFSGLT
Mflv_2841|M.gilvum_PYR-GCK MLATPALIQLLCHH--------
Mvan_3654|M.vanbaalenii_PYR-1 MLATPAFIQVLCHH--------
MMAR_5059|M.marinum_M AVVSPMILGLACRL--------
MUL_4135|M.ulcerans_Agy99 AVVSSMFLGLACRL--------
MAB_4859|M.abscessus_ATCC_1997 ISAGPLVTIALATSGALLCSP-
. .